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https://www.readbyqxmd.com/read/28529683/gd-eob-dtpa-based-magnetic-resonance-imaging-for-predicting-liver-response-to-portal-vein-embolization
#1
Janio Szklaruk, Gustavo Luersen, Jingfei Ma, Wei Wei, Michelle Underwood
AIM: To evaluate the correlation between degree of kinetic growth (kGR) of the liver following portal vein embolization (PVE) liver and the enhancement of the during the hepatobiliary phase of contrast administration and to evaluate if the enhancement can be used to predict response to PVE prior to the procedure. METHODS: Seventeen patients were consented for the prospective study. All patients had an MR of the abdomen with Gd-EOB-DTPA. Fourteen patients underwent PVE...
April 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28476245/twist-vibe-five-arterial-phase-technology-decreases-transient-severe-motion-after-bolus-injection-of-gd-eob-dtpa
#2
H Li, Y Xiao, S Wang, Y Li, X Zhong, W Situ, E Xiao, Z Zhang
AIM: To investigate whether time-resolved imaging with interleaved stochastic trajectories (TWIST)-volumetric interpolated breath-hold examination (VIBE) hepatic arterial phase imaging technique improves image quality in patients experiencing transient severe motion (TSM) during abdominal magnetic resonance imaging (MRI) with gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA). MATERIALS AND METHODS: This retrospective study compares TSM in MRI images from 28 patients with focal liver lesions imaged with gadopentetic acid (Gd-DTPA) and 28 patients with focal liver lesions imaged with Gd-EOB-DTPA...
May 2, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28474177/evaluation-of-biliary-ductal-anatomy-in-potential-living-liver-donors-comparison-between-mrcp-and-gd-eob-dtpa-enhanced-mri
#3
D Santosh, A Goel, I W Birchall, A Kumar, K H Lee, V H Patel, G Low
PURPOSE: To compare magnetic resonance cholangiopancreatography (MRCP) and Gd-EOB-DTPA-enhanced MRI in the evaluation of the biliary anatomy in potential living liver donors (LLDs). METHODS: A retrospective study was conducted in a tertiary care liver transplant center after obtaining ethics and institutional approvals. A total of 42 potential LLD MRI examinations were performed between November 2013 and March 2016. All patients underwent a standard MRI protocol which included MRCP and Gd-EOB-DTPA-enhanced MRI sequences in a single session...
May 4, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28472767/critical-analysis-of-the-major-and-ancillary-imaging-features-of-li-rads-on-127-proven-hccs-evaluated-with-functional-and-morphological-mri-lights-and-shadows
#4
Vincenza Granata, Roberta Fusco, Antonio Avallone, Francesco Filice, Fabiana Tatangelo, Mauro Piccirillo, Roberto Grassi, Francesco Izzo, Antonella Petrillo
PURPOSE: To report a critical analysis of major and ancillary MR imaging features in assessment of HCC. METHODS: Retrospectively we evaluated 70 cirrhotic patients with 173 nodules, which were subjected to MR study at 0 time (MR0), after 3 (MR3) and 6 months (MR6) using two different contrast media. EOB-GD-DTPA was injected at MR0 and MR6, while Gd-BT-DO3A at MR3. Three expert hepatic radiologists reviewed all images, recording, according to LI-RADS, the size, the presence and quality of arterial-phase hyperenhancement, washout and capsule appearance, threshold growth...
April 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28456818/hepatic-segmental-atrophy-and-nodular-elastosis-imaging-features
#5
Ishan Garg, Rondell P Graham, Wendaline M VanBuren, Ajit H Goenka, Michael S Torbenson, Sudhakar K Venkatesh
PURPOSE: To evaluate the imaging features of hepatic segmental atrophy and nodular elastosis. MATERIALS AND METHODS: In this Institutional review board (IRB)-approved, HIPAA-compliant study, we reviewed imaging features in six cases of histologically confirmed hepatic segmental atrophy (HSA) and nodular elastosis (NE). Retrospective review of ultrasound (US) in 2 patients, computed tomography (CT) in 5 patients, magnetic resonance imaging (MRI) in 4 patients, and positron emission tomography (PET) in 2 patients was performed...
April 29, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28444420/periportal-lymphatic-system-on-post-hepatobiliary-phase-gd-eob-dtpa-enhanced-mr-imaging-in-normal-subjects-and-patients-with-chronic-hepatitis-c
#6
Yasunari Yamada, Shunro Matsumoto, Hiromu Mori, Ryo Takaji, Maki Kiyonaga, Naoki Hijiya, Rika Tanoue, Kenichiro Tomonari, Shuichi Tanoue, Norio Hongo, Masayuki Ohta, Masataka Seike, Masafumi Inomata, Kazunari Murakami, Masatsugu Moriyama
PURPOSE: We sought to evaluate visualization of periportal lymphatics and lymph nodes (lymphatic system) on Gd-EOB-DTPA-enhanced magnetic resonance (MR) images using a fat-suppressed T2-weighted sequence with 3-dimensional (3D) volume isotropic turbo spin echo acquisition (VISTA) at 3.0 T in normal subjects and patients with chronic hepatitis C. METHODS: MR imaging was performed in 254 subjects between June 2013 and May 2016. After applying inclusion and exclusion criteria, the final population was 31 normal subjects and 34 patients with chronic hepatitis C...
April 25, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28396918/comparison-of-10-and-20-min-hepatobiliary-phase-images-on-gd-eob-dtpa-enhanced-mri-t1-mapping-for-liver-function-assessment-in-clinic
#7
Zhi-Peng Zhou, Li-Ling Long, Wei-Jia Qiu, Ge Cheng, Li-Juan Huang, Teng-Fei Yang, Zhong-Kui Huang
PURPOSE: To compare hepatobiliary phase (HBP) images obtained 10 and 20 min after Gd-EOB-DTPA-enhanced MRI for liver function assessment in clinic on 3.0 T MR imaging. METHODS: 103 patients were separated into four groups: 38 patients for the normal liver function (NLF) group, 33 patients for the liver cirrhosis with Child-Pugh A (LCA) group, 21 patients for the liver cirrhosis with Child-Pugh B group, and 11 patients for a liver cirrhosis with Child-Pugh C group...
April 10, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28365784/magnetic-resonance-findings-of-hepatic-epithelioid-hemangioendothelioma-emphasis-on-hepatobiliary-phase-using-gd-eob-dtpa
#8
Jeong Hyun Lee, Woo Kyoung Jeong, Young Kon Kim, Won Jae Lee, Sang Yun Ha, Kyoung Won Kim, Jihun Kim
PURPOSE: To examine the characteristic features of hepatic epithelioid hemangioendothelioma (HEH) on magnetic resonance imaging (MRI) using Gd-EOB-DTPA. MATERIAL AND METHODS: Twelve patients (mean age, 50 years; male:female = 6:6) who were pathologically confirmed to have HEH in two tertiary institutions were retrospectively investigated. For qualitative analysis, the MRI features of HEH including core pattern were characterized, and lesions were divided into core and non-core groups...
April 1, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28355258/the-value-of-gd-eob-dtpa-enhanced-mr-imaging-in-characterizing-cirrhotic-nodules-with-atypical-enhancement-on-gd-dtpa-enhanced-mr-images
#9
Yi-Chun Wang, Chen-Te Chou, Ching-Po Lin, Yao-Li Chen, Yung-Fang Chen, Ran-Chou Chen
PURPOSE: To evaluate the utility of Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) in characterizing atypically enhanced cirrhotic nodules detected on conventional Gd-DTPA-enhanced MR images. MATERIALS AND METHODS: We enrolled 61 consecutive patients with 88 atypical nodules seen on conventional Gd-DTPA-enhanced MR images who underwent Gd-EOB-DTPA-enhanced MRI within a 3-month period. Using a reference standard, we determined that 58 of the nodules were hepatocellular carcinoma (HCC) and 30 were dysplastic nodules (DNs)...
2017: PloS One
https://www.readbyqxmd.com/read/28314197/use-of-hepatobiliary-phase-images-in-gd-eob-dtpa-enhanced-mri-of-breast-cancer-hepatic-metastasis-to-predict-response-to-chemotherapy
#10
Hyun Ji Lee, Chang Hee Lee, Jeong Woo Kim, Yang Shin Park, Jongmee Lee, Kyeong Ah Kim
OBJECTIVES: To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer. METHODS: 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a "target" or "non-target" appearance. The relationship of appearance or SI ratio with tumor response was analyzed. RESULTS: A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77...
May 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28271531/value-of-contrast-enhanced-sonography-of-small-hepatocellular-carcinoma-with-sonazoid-prior-to-radiofrequency-ablation
#11
So Jung Lee, Hyung Jin Won, Kyung Won Kim, Yong Moon Shin, Pyo Nyun Kim
BACKGROUND: We aimed to determine the value of contrast-enhanced sonography (CEUS) with Sonazoid prior to percutaneous radiofrequency ablation (RFA) of small (<3 cm) hepatocellular carcinoma (HCC). METHODS: This prospective study was approved by our institutional review board and informed consent was obtained. The following criteria were used for study enrollment: (1) cirrhotic patients with HCCs found by contrast-enhanced CT or Gd-EOB-DTPA-enhanced MRI; (2) a single HCC <3 cm in longest diameter or multinodular HCCs (<3) with each tumor <3 cm in longest diameter; and (3) indeterminate identification of the index tumor from the surrounding cirrhosis-related pseudolesions on conventional US...
March 8, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28266528/gd-eob-dtpa-enhanced-mri-for-evaluation-of-liver-function-comparison-between-signal-intensity-based-indices-and-t1-relaxometry
#12
Michael Haimerl, Niklas Verloh, Florian Zeman, Claudia Fellner, Dominik Nickel, Sven A Lang, Andreas Teufel, Christian Stroszczynski, Philipp Wiggermann
Gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) is a paramagnetic hepatobiliary magnetic resonance (MR) contrast agent. Due to its OATP1B1/B3-dependent hepatocyte-specific uptake and paramagnetic properties increasing evidence has emerged to suggest that Gd-EOB-DTPA-enhanced MRI can be potentially used for evaluation of liver function. In this paper we compare the diagnostic performance of Gd-EOB-DTPA-enhanced relaxometry-based and commonly used signal-intensity (SI)-based indices, including the hepatocellular uptake index (HUI) and SI-based indices corrected by spleen or muscle, for evaluation of liver function, determined using the Indocyanin green clearance (ICG) test...
March 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28249571/evaluating-segmental-liver-function-using-t1-mapping-on-gd-eob-dtpa-enhanced-mri-with-a-3-0-tesla
#13
Zhi-Peng Zhou, Li-Ling Long, Wei-Jia Qiu, Ge Cheng, Li-Juan Huang, Teng-Fei Yang, Zhong-Kui Huang
BACKGROUND: Assessing the liver function provides valuable information to evaluate surgical risk and plan accordingly. Current studies focus on whole liver function evaluation. However, assessment of segmental liver function is equally important in the clinical practice. The purpose of this study was to investigate whether Gd-EOB-DTPA-enhanced MRI can evaluate the liver function of each segment by using T1 mapping at 3 Tesla MRI. METHODS: One hundred three patients were classified into one of 4 groups: a normal liver function (NLF) group (n = 38), a liver cirrhosis with Child-Pugh A (LCA) group (n = 33), a liver cirrhosis with Child-Pugh B (LCB) group (n = 21), and a liver cirrhosis with Child-Pugh C (LCC) group (n = 11)...
March 1, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28240635/comparison-of-the-timing-of-hepatic-arterial-phase-and-image-quality-using-test-bolus-and-bolus-tracking-techniques-in-gadolinium-ethoxybenzyl-diethylenetriamine-pentaacetic-acid-enhanced-hepatic-dynamic-magnetic-resonance-imaging
#14
Yuji Iyama, Takeshi Nakaura, Koichi Yokoyama, Masafumi Kidoh, Daisuke Utsunomiya, Seitaro Oda, Tomohiro Namimoto, Yasuyuki Yamashita
OBJECTIVES: The aim of this study was to compare the image quality, the degree of artifacts and the percentage of timing of the optimal hepatic arterial phase (HAP) between test-bolus and bolus-tracking methods on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI). METHODS: In this prospective study, 60 patients who underwent 3-dimensional dynamic Gd-EOB-DTPA-enhanced hepatic 3-T MRI were enrolled in this study...
February 24, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28238007/radiation-induced-liver-injury-after-3d-conformal-radiotherapy-for-hepatocellular-carcinoma-quantitative-assessment-using-gd-eob-dtpa-enhanced-mri
#15
Yoshiyuki Fukugawa, Tomohiro Namimoto, Ryo Toya, Tetsuo Saito, Hideaki Yuki, Tomohiko Matsuyama, Osamu Ikeda, Yasuyuki Yamashita, Natsuo Oya
Focal liver reaction (FLR) appears in the hepatobiliary-phase images of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging (Gd-EOB-DTPA-enhanced MRI) following radiotherapy (RT). We investigated the threshold dose (TD) for FLR development in 13 patients with hepatocellular carcinoma (HCC) who underwent three-dimensional conformal radiotherapy (3D-CRT) with 45 Gy in 15 fractions. FLR volumes (FLRVs) were calculated based on planning CT images by referring to fused hepatobiliary- phase images...
February 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/28237298/assessment-of-liver-fibrosis-using-t1-mapping-on-gd-eob-dtpa-enhanced-magnetic-resonance
#16
Ruo Fan Sheng, He Qing Wang, Li Yang, Kai Pu Jin, Yan Hong Xie, Cai Xia Fu, Meng Su Zeng
BACKGROUND: Few studies have investigated the value of Gd-EOB-DTPA-enhanced T1 mapping in exact fibrosis staging, especially its correlation with hepatic molecular transporters. AIMS: To investigate the diagnostic value of Gd-EOB-DTPA-enhanced T1 mapping in staging liver fibrosis and its relationship with hepatic molecular transporters. METHODS: Thirty rats were divided into the carbon tetrachloride-induced fibrosis groups and a control group...
February 22, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28217239/diagnostic-accuracy-of-gd-eob-dtpa-for-detection-hepatocellular-carcinoma-hcc-a-comparative-study-with-dynamic-contrast-enhanced-magnetic-resonance-imaging-mri-and-dynamic-contrast-enhanced-computed-tomography-ct
#17
Massimo Imbriaco, Serena De Luca, Milena Coppola, Mario Fusari, Michele Klain, Marta Puglia, Pierpaolo Mainenti, Raffaele Liuzzi, Simone Maurea
BACKGROUND: To compare the diagnostic accuracy of hepato-biliary (HB) phase with gadolinium-ethoxybenzyl-diethylenetriamine-pentaacetic acid (Gd-EOB-DTPA) with dynamic contrast-enhanced MR imaging (DCEMRI) and contrast-enhanced CT (DCECT) for hepatocellular carcinoma (HCC) detection. MATERIAL/METHODS: 73 patients underwent DCECT and Gd-EOB-DTPA-3T-MR. Lesions were classified using a five-point confidence scale. Reference standard was a combination of pathological evidence and tumor growth at follow-up CT/MR at 12 months...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28195848/influence-of-indocyanine-green-on-hepatic-gd-eob-dtpa-uptake-a-proof-of-concept-study-in-mice
#18
Hiroyuki Akai, Koichiro Yasaka, Masanori Nojima, Yusuke Inoue, Kuni Ohtomo, Shigeru Kiryu
OBJECTIVES: The aim of this study was to explore the influence of indocyanine green (ICG) on hepatic uptake of gadolinium ethoxybenzyldiethylenetriaminepenta-acetic acid (Gd-EOB-DTPA). MATERIALS AND METHODS: Groups of 6 female C57BL6 mice were injected with 5 mg/kg ICG, 20 mg/kg ICG, or phosphate-buffered saline (control group) 10 minutes before the injection of Gd-EOB-DTPA; identical 3-dimensional gradient echo T1-weighted images were subsequently obtained to create time-intensity curves and to measure the peak contrast ratios (CRs) of liver parenchyma...
February 10, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28181823/diagnostic-value-of-gd-eob-dtpa-enhanced-mr-cholangiography-in-non-invasive-detection-of-postoperative-bile-leakage
#19
Melahat Kul, Ayşe Erden, Ebru Düşünceli Atman
OBJECTIVE: To assess the diagnostic value of dynamic T1 weighted (T1w) gadolinium ethoxybenzyl diethylenetriamine penta-acetic acid (Gd-EOB-DTPA)-enhanced MR cholangiography (MRC) for the detection of active bile leaks. METHODS: A total of 28 patients with suspected biliary leakage who underwent routine T2 weighted (T2w) MRC and T1w GD-EOB-DTPA-enhanced MRC at our institution from February 2013 to June 2016 were included in this study. The image sets were retrospectively analyzed in consensus by three radiologists...
April 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28166142/detection-and-viability-of-colorectal-liver-metastases-after-neoadjuvant-chemotherapy-a-multiparametric-pet-ct-mri-study
#20
COMPARATIVE STUDY
Vincent Dunet, Nermin Halkic, John O Prior, Anass Anaye, Reto A Meuli, Christine Sempoux, Alban Denys, Sabine Schmidt
PURPOSE: The aim of this study was to compare combined gadolinium-ethoxybenzyl-diethylenetriamine-pentaacetic acid (Gd-EOB-DTPA)-enhanced and diffusion-weighted (DW) MRI with IV contrast-enhanced F-FDG PET/CT to detect and assess the viability of colorectal liver metastases (CLMs) after neoadjuvant chemotherapy (NAC). PATIENTS AND METHODS: After NAC, 45 patients with CLMs were prospectively enrolled and underwent combined Gd-EOB-DTPA-enhanced and DW-MRI and contrast-enhanced F-FDG PET/CT...
April 2017: Clinical Nuclear Medicine
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