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https://www.readbyqxmd.com/read/29150394/efficacy-of-prostatic-artery-embolization-for-catheter-dependent-patients-with-large-prostate-sizes-and-high-comorbidity-scores
#1
Shivank Bhatia, Vishal K Sinha, Bruce R Kava, Christopher Gomez, Sardis Harward, Sanoj Punnen, Issam Kably, Jeffrey Miller, Dipen J Parekh
PURPOSE: To evaluate efficacy and safety of prostate artery embolization (PAE) in urinary catheter-dependent patients with large prostate volumes and high comorbidity scores. MATERIALS AND METHODS: A retrospective single-center review was conducted of 30 patients with urinary retention at time of PAE from November 2014 through February 2017. Mean (range) age was 73.1 years (48-94 y), age-adjusted Charlson comorbidity index was 4.5 (0-10), duration of urinary retention was 63...
November 15, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29145066/relationship-between-follicular-dynamics-and-oocyte-maturation-during-in%C3%A2-vitro-culture-as-a-non-invasive-sign-of-caprine-oocyte-meiotic-competence
#2
J Cadenas, C Maside, A C A Ferreira, L A Vieira, J Leiva-Revilla, V M Paes, B G Alves, F Z Brandão, A P R Rodrigues, M B Wheeler, J R Figueiredo
The search for non-invasive signs of oocyte meiotic competence is very important for the development of in vitro follicle culture (IVFC) systems. The aims of the present study were: (1) to investigate the effect of in vitro maturation (IVM) of in vivo grown goat COCs, in group or individually, on oocyte chromatin configuration (Experiment 1), and (2) the influence of IVFC period (12 vs. 18 days) on the ability of the oocyte to resume meiosis immediately after IVFC (before in vitro maturation; IVM), or after IVM (Experiment 2)...
November 4, 2017: Theriogenology
https://www.readbyqxmd.com/read/29145058/occurrence-distribution-and-ecological-risks-of-phthalate-esters-in-the-seawater-and-sediment-of-changjiang-river-estuary-and-its-adjacent-area
#3
Ze-Ming Zhang, Hong-Hai Zhang, Jing Zhang, Qian-Wen Wang, Gui-Peng Yang
A total of 133 seawater samples and 17 sediment samples were collected from 81 sampling sites in the Changjiang River Estuary and its adjacent area and were analyzed for 16 phthalate esters (PAEs). The Σ16 PAE concentrations in the seawater and sediment samples ranged from 180.3ng·L(-1) to 3421ng·L(-1) and from 0.48μg·g(-1) to 29.94μg·g(-1)dry weight (dw), respectively, with mean values of 943.6ng·L(-1) and 12.88μg·g(-1). The distribution of ∑16PAE concentrations in the water column showed that PAE concentrations in the bottom samples were higher than those in the surface samples (except the transect C located inside the Changjiang River Estuary), with the maxima appearing in the bottom layer at the offshore stations...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29137880/microbioma-and-probiotics-from-gut-to-mars
#4
EDITORIAL
Bruno Acatauassú Paes Barreto
No abstract text is available yet for this article.
October 27, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29133319/identification-of-factors-associated-with-resilience-in-medical-students-through-a-cross-sectional-census
#5
Anna Christina Pinho de Oliveira, André Paes Goulart Machado, Renata Nunes Aranha
OBJECTIVES: Research on resilience has been gaining momentum, and it has already been shown that increased resilience creates positive changes at the individual and collective levels. Understanding of the factors associated with resilience may guide specific actions directed towards different populations. The objective of this study was to investigate these associated factors within a population of medical students. DESIGN: Cross-sectional census. SETTING: A public medical school in the state of Rio de Janeiro, Brazil...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29130704/-relationship-between-anthropometric-health-indexes-with-food-consumption-in-physically-active-elderly
#6
Pablo Antonio Valdés-Badilla, Andrés Godoy-Cumillaf, Jenny Ortega-Spuler, Daniela Díaz-Aravena, Nibaldo Castro-Garrido, Luis Sandoval-Muñoz, Tomás Herrera-Valenzuela, Antonio López-Fuenzalida, Rodrigo Vargas-Vitoria, Samuel Durán-Aguero
INTRODUCTION: Programs focused on active aging do not always have actions to guide the elderly about healthy eating. Therefore, the concordance between the feeding habits and the morphological characteristics of this population group is little known. OBJECTIVE: To correlate the anthropometric health indexes with the frequency of food consumption in physically active elderly (PAE). METHODS: The sample consisted of 307 physically active Chilean elders of both sexes (8...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29130355/adherence-and-outcomes-a-systematic-review-of-palivizumab-utilization
#7
Sophie K Wong, Abby Li, Krista L Lanctôt, Bosco Paes
Palivizumab is a humanized monoclonal antibody used for respiratory syncytial virus (RSV) prophylaxis. RSV is the primary cause of lower respiratory tract infection in children aged <2 years, and can give rise to high-burden hospitalization and respiratory complications in later life. Adherence to a monthly dosing regimen, both in timing and injection number, is essential to sustain therapeutic levels of palivizumab and maintain protective status. Deviation from the approved dosing schedule may reduce the efficacy of palivizumab and increase the risk of breakthrough RSV infection and hospitalization...
November 13, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/29128622/efficacy-and-tolerability-of-pharmacological-interventions-for-pulmonary-arterial-hypertension-a-network-meta-analysis
#8
Hongjing Lin, Mupeng Wang, Ying Yu, Zeyu Qin, Xin Zhong, Jiahui Ma, Fangbo Zhao, Xueli Zhang
PURPOSE: This network meta-analysis (NMA) is designed to compare the efficacy and tolerability of various therapies and combinations for pulmonary arterial hypertension (PAH). METHOD: We conducted a systematic search in databases PubMed, Embase, and Cochrane Library. Treatment efficacy and tolerability were compared by synthesizing direct and indirect evidence. The surface under the curve ranking area was utilized to rank multiple interventions. RESULT: A total of 43 randomized clinical trials were included in our NMA...
November 8, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29121962/direct-interaction-with-14-3-3%C3%AE-promotes-surface-expression-of-best1-channel-in-astrocyte
#9
Soo-Jin Oh, Junsung Woo, Young-Sun Lee, Minhee Cho, Eunju Kim, Nam-Chul Cho, Jae-Yong Park, Ae Nim Pae, C Justin Lee, Eun Mi Hwang
BACKGROUND: Bestrophin-1 (Best1) is a calcium-activated anion channel (CAAC) that is expressed broadly in mammalian tissues including the brain. We have previously reported that Best1 is expressed in hippocampal astrocytes at the distal peri-synaptic regions, called microdomains, right next to synaptic junctions, and that it disappears from the microdomains in Alzheimer's disease mouse model. Although Best1 appears to be dynamically regulated, the mechanism of its regulation and modulation is poorly understood...
November 9, 2017: Molecular Brain
https://www.readbyqxmd.com/read/29120886/comparison-of-alcohol-related-neurodevelopmental-disorders-and-neurodevelopmental-disorders-associated-with-prenatal-alcohol-exposure-diagnostic-criteria
#10
Sean Johnson, Chelsie Leigh Moyer, Marilyn G Klug, Larry Burd
OBJECTIVE: Recently, increased attention has been focused on the diagnosis of the most prevalent category of fetal alcohol spectrum disorders, alcohol-related neurodevelopmental disorders (ARNDs). In 2013, proposed criteria for neurodevelopmental disorders associated with prenatal alcohol exposure (ND-PAE) were included in the appendix of the latest revision of the Diagnostic and Statistical Manual of Mental Disorders. The concordance of the 2 sets of criteria is unknown. This study examines the overlap in diagnostic criteria for ND-PAE and the ARND Behavioral Checklist in children...
November 8, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29119699/effect-of-follistatin-on-pre-implantational-development-of-pig-parthenogenetic-embryos
#11
Yunsheng Li, Xing Liu, Zhen Chen, Dandan Song, Jie Yang, Xiaoyuan Zuo, Zubing Cao, Ya Liu, Yunhai Zhang
The present study was designed to explore effects of follistatin (FST) on pre-implantational development of parthenogenetically activated embryos (PAEs) in pigs. First, we investigated the FST messenger RNA expression level and dynamic FST protein expression patterns in porcine oocytes and PAEs. Then, PAEs were placed in embryo culture medium supplemented with 10 ng/mL of FST-288, FST-300, and FST-315. Next, PAEs were cultured with 0, 1, 10 and 100 ng/mL of FST-315 protein throughout the in vitro culture (IVC) duration...
November 9, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/29119403/evaluation-of-the-efficiency-of-single-inhaler-combination-therapy-with-budesonide-formoterol-fumarate-in-patients-with-bronchial-asthma-in-daily-clinical-practice
#12
Michał Pirożyński, Piotr Hantulik, Agnieszka Almgren-Rachtan, Jerzy Chudek
INTRODUCTION: The effectiveness of single-inhaler budesonide/formoterol fumarate combination therapy for asthma has been previously shown for the original product. The aim of this nonrandomized, open-label, postauthorization efficacy study (PAES) real-life clinical assessment was to evaluate the clinical effectiveness of a second product (Bufomix Easyhaler(®)) in the daily clinical practice of asthma therapy. METHODS: This multicenter PAES was conducted by 220 unselected allergologists and pulmonologists who enrolled 2200 adult outpatients (age 49...
November 8, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/29116313/solitary-pancreatic-metastasis-from-breast-cancer-case-report-and-review-of-literature
#13
Márcio Apodaca-Rueda, Fábio Henrique Mendonça Chaim, Milena da Silva Garcia, Helena Paes de Almeida de Saito, Martinho Antonio Gestic, Murillo Pimentel Utrini, Francisco Callejas-Neto, Elinton Adami Chaim, Everton Cazzo
ABSTRACT: HASH(0x4336418) CONTEXT: Pancreatic metastases from primary malignant tumors at other sites are rare, constituting about 2% of the neoplasms that affect the pancreas. Pancreatic metastasis from breast cancer is extremely rare and difficult to diagnose, because its clinical and radiological presentation is similar to that of a primary pancreatic tumor. CASE REPORT: A 64-year-old female developed a lesion in the pancreatic tail 24 months after neoadjuvant therapy, surgery and adjuvant radiation therapy for right-side breast cancer (ductal carcinoma)...
November 6, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29112835/biodegradation-of-di-n-butyl-phthalate-dbp-by-a-novel-endophytic-bacillus-megaterium-strain-yjb3
#14
Nai-Xian Feng, Jiao Yu, Ce-Hui Mo, Hai-Ming Zhao, Yan-Wen Li, Bing-Xiao Wu, Quan-Ying Cai, Hui Li, Dong-Mei Zhou, Ming-Hung Wong
Phthalic acid esters (PAEs) are a group of recalcitrant and hazardous organic compounds that pose a great threat to both ecosystem and human beings. A novel endophytic strain YJB3 that could utilize a wide range of PAEs as the sole carbon and energy sources for cell growth was isolated from Canna indica root tissue. It was identified as Bacillus megaterium based on morphological characteristics and 16S rDNA sequence homology analysis. The degradation capability of the strain YJB3 was investigated by incubation in mineral salt medium containing di-n-butyl-phthalate (DBP), one of important PAEs under different environmental conditions, showing 82...
November 4, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29110638/application-of-the-2016-diagnostic-approach-for-autoimmune-encephalitis-from-lancet-neurology-to-chinese-patients
#15
Lin Li, Lin Sun, Rong Du, Yuanchu Zheng, Feifei Dai, Qiuying Ma, Jiawei Wang
BACKGROUND: A unified clinical approach to diagnose autoimmune encephalitis was published in Lancet Neurology in 2016. Purpose of our study is to examine the feasibility and reasonability of the 2016 "A clinical approach to diagnosis of autoimmune encephalitis" in China with a retrospective study. METHODS: We retrospectively collected 95 cases of autoimmune encephalitis and non autoimmune encephalitis cases with detailed clinical data from Beijing Tongren Hospital and the China National Knowledge Infrastructure (CNKI)...
November 6, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29107713/the-enduring-impact-of-neurulation-stage-alcohol-exposure-a-combined-behavioral-and-structural-neuroimaging-study-in-adult-male-and-female-c57bl-6j-mice
#16
E W Fish, L A Wieczorek, A Rumple, M Suttie, S S Moy, P Hammond, S E Parnell
Prenatal alcohol exposure (PAE) can cause behavioral and brain alterations over the lifespan. In animal models, these effects can occur following PAE confined to critical developmental periods, equivalent to the third and fourth weeks of human gestation, before pregnancy is usually recognized. The current study focuses on PAE during early neurulation and examines the behavioral and brain structural consequences that appear in adulthood. On gestational day 8 C57BL/6J dams received two alcohol (2.8g/kg, i.p), or vehicle, administrations, four hours apart...
October 28, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29107425/novel-lck-fms-inhibitors-based-on-phenoxypyrimidine-scaffold-as-potential-treatment-for-inflammatory-disorders
#17
Ahmed Karam Farag, Ahmed Elkamhawy, Ashwini M Londhe, Kyung-Tae Lee, Ae Nim Pae, Eun Joo Roh
Tyrosine kinases including LCK and FMS are involved in inflammatory disorders as well as many types of cancer. Our team has designed and synthesized thirty novel pyrimidine based inhibitors targeting LCK, classified into four different series (amides, ureas, imines (Schiff base) and benzylamines). Twelve of them showed nanomolar IC50 values. Compound 7g showed excellent selectivity profile and was selectively potent over FMS kinase (IC50 value of 4.6 nM). Molecular docking study was performed to help us rationalize the obtained results and predict the possible binding mode for our compounds in both LCK and FMS...
December 1, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29102194/biological-responses-of-neotropical-freshwater-fish-lophiosilurus-alexandri-exposed-to-ammonia-and-nitrite
#18
Márcio José Dos Santos Silva, Franklin Fernando Batista da Costa, Fabiola Paes Leme, Rodrigo Takata, Deliane Cristina Costa, Cristiano Campos Mattioli, Ronald Kennedy Luz, Kleber Campos Miranda-Filho
This study aimed to elucidate the responses of the Neotropical fish Lophiosilurus alexandri exposed to ammonia and nitrite, following a period of recovering. Acute toxicity tests lasted 96h, subchronic toxicity tests lasted eight days and the detoxification trial lasted four days. Groups of 12 juveniles were maintained in 90-L tanks and treated with increasing concentrations of ammonia and nitrite, except during the recovery test. All treatments were performed with two replicates. The median lethal concentrations (LC50) of 24, 48, 72 and 96h were estimated at 30...
October 25, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29101691/a-national-assessment-of-the-effect-of-intensive-agro-land-use-practices-on-nonpoint-source-pollution-using-emission-scenarios-and-geo-spatial-data
#19
Dong Zhuo, Liming Liu, Huirong Yu, Chengcheng Yuan
China's intensive agriculture has led to a broad range of adverse impacts upon ecosystems and thereby caused environmental quality degradation. One of the fundamental problems that face land managers when dealing with agricultural nonpoint source (NPS) pollution is to quantitatively assess the NPS pollution loads from different sources at a national scale. In this study, export scenarios and geo-spatial data were used to calculate the agricultural NPS pollution loads of nutrient, pesticide, plastic film residue, and crop straw burning in China...
November 3, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29096413/the-physical-activity-environment-and-academic-achievement-in-massachusetts-schoolchildren
#20
Sarah A Amin, Catherine M Wright, Rebecca Boulos, Virginia R Chomitz, Kenneth Chui, Christina D Economos, Jennifer M Sacheck
BACKGROUND: A supportive school-based physical activity environment (PAE) is integral to children's physical activity behaviors, but less understood is its association with academic achievement. We aimed to assess the association between PAE and academic performance and whether a stronger relationship exists in lower-income schools (LIS) compared to middle-income schools (MIS). METHODS: Schoolchildren (grades 3rd to 5th) were recruited from 17 Massachusetts public schools...
December 2017: Journal of School Health
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