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traumatic brain trauma

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https://www.readbyqxmd.com/read/28921171/high-fibrin-fibrinogen-degradation-product-to-fibrinogen-ratio-is-associated-with-28-day-mortality-and-massive-transfusion-in-severe-trauma
#1
D H Lee, B K Lee, S M Noh, Y S Cho
PURPOSE: There is a lack of association between coagulation biomarkers and long-term mortality in severe trauma. We aimed to investigate the association between coagulation biomarkers on admission and outcome of late stage of trauma. METHODS: This retrospective observational study included patients admitted with severe trauma between 2012 and 2015. We used the area under the receiver operating characteristic curve (AUROC) of coagulation biomarkers to determine 28-day mortality...
September 18, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28919762/risk-of-post-traumatic-epilepsy-after-severe-head-injury-in-patients-with-at-least-one-seizure
#2
Wei Chen, Ming-De Li, Gui-Fang Wang, Xia-Feng Yang, Lin Liu, Fan-Gang Meng
BACKGROUND: To explore the incidence and risk factors, including type of seizures for post-traumatic epilepsy (PTE) after severe traumatic brain injury (TBI). SUBJECTS AND METHODS: This was a retrospective follow-up study of patients discharged from Liaocheng People's Hospital between March 2011 and June 2015 with a diagnosis of post-traumatic seizures. Risk factors for PTE were evaluated in 68 inpatients by using Kaplan-Meier curves and the Cox model. RESULTS: Complete clinical information was available for 68 patients...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28917584/pneumatoceles-in-pediatric-blunt-trauma-common-and-benign
#3
Lindsey B Armstrong, David P Mooney
INTRODUCTION: Traumatic pneumatoceles are reported to be rare in children and to have an uncertain clinical significance. We report a single institution series of traumatic pneumatoceles to better define their frequency and clinical significance. METHODS: After obtaining approval from the IRB, data were extracted from the trauma registry of a level 1 pediatric trauma center on children diagnosed with a pulmonary contusion (International Classification of Diseases-9th edition diagnosis codes: 861...
August 7, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28916852/pediatric-head-trauma-an-extensive-review-on-imaging-requisites-and-unique-imaging-findings
#4
REVIEW
F C Sarioglu, H Sahin, Y Pekcevik, O Sarioglu, O Oztekin
The effects of trauma in children are different due to association with some anatomical and physiological differences compared with adults. The role of neuroimaging gains importance in early detection of traumatic brain injuries and prevention of secondary post-traumatic complications. Many algorithms are described for children with head trauma to decide the necessity of a computed tomography scan. The aims of this article are to describe differences of these algorithms, the mechanism of traumatic brain injury with radiological imaging findings in the pediatric population, and explain complications of undiagnosed traumatic brain lesions...
September 15, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28912029/inclusion-of-highest-glasgow-coma-scale-motor-score-in-mortality-risk-adjustment-for-benchmarking-of-trauma-center-performance
#5
David Gomez, James P Byrne, Aziz S Alali, Wei Xiong, Chris Hoeft, Melanie Neal, Harris Subacius, Avery B Nathens
BACKGROUND: The Glasgow Coma Scale (GCS) score is the most widely utilized measure of traumatic brain injury (TBI) severity. Currently, the arrival GCS motor score (mGCS) is used in risk-adjustment models for external benchmarking of mortality. However, there is evidence that the highest mGCS in the first 24 hours after injury might be a better predictor of death. Our objective was to evaluate the impact of including highest mGCS on the performance of risk-adjustment models and subsequent external benchmarking results...
September 11, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28900824/external-nasal-neuralgia-an-update
#6
REVIEW
Hida Nierenburg, Morgane Swift Morris
PURPOSE OF REVIEW: External nasal neuralgia is a rare syndrome of atypical facial pain for which there is limited reports in the scientific literature. We aim to review diagnosis and provide an update on treatments for this rare condition. RECENT FINDINGS: Etiology has been documented as post-traumatic due to direct trauma to the nose area and in few case reports, idiopathic. Sensory innervation of the nose arises from the ophthalmic and maxillary divisions of the trigeminal nerve...
September 13, 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28889182/benign-extracerebral-fluid-collection-complicated-by-subdural-hematoma-and-fluid-collection-clinical-characteristics-and-management
#7
Hee Chang Lee, Sangjoon Chong, Ji Yeoun Lee, Jung-Eun Cheon, Ji Hoon Phi, Seung-Ki Kim, In-One Kim, Kyu-Chang Wang
INTRODUCTION: Benign extracerebral fluid collection (bECFC) can be complicated by subdural hematoma (SDH) or subdural fluid collection (SDFC). The etiology, natural history, and management strategy for SDH/SDFC in bECFC are not fully understood. We retrospectively reviewed the cases of bECFC patients complicated with SDH/SDFC and tried (1) to confirm the fact that bECFC children are vulnerable to SDH/SDFC, (2) to investigate the clinical significance of 'trauma history' witnessed by a caregiver, and (3) to determine optimal management for them...
September 9, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28888667/preimmunization-with-a-heat-killed-preparation-of-mycobacterium-vaccae-enhances-fear-extinction-in-the-fear-potentiated-startle-paradigm
#8
James H Fox, James E Hassell, Philip H Siebler, Mathew R Arnold, Andrew K Lamb, David G Smith, Heidi E W Day, Tessa M Smith, Emma M Simmerman, Alexander A Outzen, Kaley S Holmes, Christopher J Brazell, Christopher A Lowry
The hygiene hypothesis or "Old Friends" hypothesis proposes that inflammatory diseases are increasing in modern urban societies, due in part to reduced exposure to microorganisms that drive immunoregulatory circuits, and a failure to terminate inappropriate inflammatory responses. Inappropriate inflammation is also emerging as a risk factor for trauma-related, anxiety, and affective disorders, including posttraumatic stress disorder (PTSD), which is characterized as persistent re-experiencing of the trauma after a traumatic experience...
September 6, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28886498/the-neurobiology-of-brain-recovery-from-traumatic-stress-a-longitudinal-dti-study
#9
Linghui Meng, Ying Chen, Xin Xu, Taolin Chen, Su Lui, Xiaoqi Huang, John A Sweeney, Kaiming Li, Qiyong Gong
BACKGROUND: Previous studies demonstrated decreased brain microstructure integrity in people that were exposed to extreme life stress but did not meet posttraumatic stress disorder (PTSD) diagnostic criteria. It is unclear how the brain recovers from traumatic stress in these trauma-exposed non-PTSD people (TENP). METHODS: Twenty-two TENP individuals were recruited from the most affected area of Wenchuan quake, and scanned twenty-five days after the quake and at a two-year follow-up...
August 30, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28884559/artificial-neural-network-predicts-hemorrhagic-contusions-following-decompressive-craniotomy-in-traumatic-brain-injury
#10
Jian-Li Wang, Guo-Liang Jin, Zi-Gang Yuan
OBJECTIVE: This study aimed to explore relevant factors of hemorrhagic contusions following decompressive craniotomy (DC) in traumatic brain injury (TBI), and create an artificial neural network (ANN) prediction model of the risk factors of hemorrhagic contusions. METHODS: This study analyzed 425 patients with TBI who underwent DC in the Neurosurgery Department of Shaoxing People's Hospital between 2009 and 2014. Patients were divided into two groups according to the first postoperative CT scans: hemorrhage group and non-hemorrhage group...
September 7, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28884427/effect-of-oleuropein-on-cognitive-deficits-and-changes-in-hippocampal-brain-derived-neurotrophic-factor-and-cytokine-expression-in-a-rat-model-of-post-traumatic-stress-disorder
#11
Bombi Lee, Insop Shim, Hyejung Lee, Dae-Hyun Hahm
Post-traumatic stress disorder (PTSD) is a condition that develops after an individual has experienced a major trauma. This psychopathological response to traumatic stressors induces learning and memory deficits in rats. Oleuropein (OLE), a major compound in olive leaves, has been reported to possess several pharmacological properties, including anti-cancer, anti-diabetic, anti-atherosclerotic and neuroprotective activities. However, the cognitive effects of OLE and its mechanism of action have remained unclear in PTSD...
September 7, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/28884108/characteristics-and-clinical-aspects-of-patients-with-spinal-cord-injury-undergoing-surgery
#12
João Simão de Melo-Neto, Lara Eduarda Leite Vidotto, Fabiana de Campos Gomes, Dionei Freitas de Morais, Waldir Antonio Tognola
OBJECTIVE: To identify the characteristics of patients with spinal cord injury (SCI) undergoing surgery. METHODS: Previously, 321 patients with SCI were selected. Clinical and socio-demographic variables were collected. RESULTS: A total of 211 patients were submitted to surgery. Fall and injuries in the upper cervical and lumbosacral regions were associated with conservative treatment. Patients with lesions in the lower cervical spine, worse neurological status, and unstable injuries were associated with surgery...
June 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28882376/a-novel-approach-to-improving-the-interpretation-of-ct-brain-in-trauma
#13
L R Evans, M C Fitzgerald, D Varma, B Mitra
BACKGROUND: Computed tomography of the brain (CTB) has a fundamental role in the diagnosis and management of traumatic brain injury (TBI). There may be substantial discordance between initial CTB interpretation by emergency clinicians and the final radiology report. This study aimed to assess the utility of a structured reporting template in improving the accuracy of CTB interpretation by emergency clinicians. METHOD: A prospective pre- and post-intervention cohort study was undertaken using a study population of emergency medicine trainees...
September 4, 2017: Injury
https://www.readbyqxmd.com/read/28881256/structural-brain-correlates-of-resilience-to-traumatic-stress-in-dutch-police-officers
#14
Steven J A van der Werff, Bernet M Elzinga, Annika S Smit, Nic J A van der Wee
OBJECTIVE: Neurobiological research has traditionally focused on vulnerability rather than on resilience to severe stress. So far, only a few neuroimaging studies examining resilience have used designs that allow disentangling of the neural correlates of resilience from those related to psychopathology or trauma-exposure. The aim of this study was to identify structural brain correlates of resilience, and their correlations with behavioral measures. METHOD: MRI scanning was performed in three groups of police officers: (1) a resilient group (N=29; trauma-exposed, no psychopathology), (2) a vulnerable group (N=33; trauma-exposed, psychopathology), and (3) a control group (N=19; no trauma, no psychopathology)...
August 26, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28880678/assault-related-mild-traumatic-brain-injury-expectations-of-injury-outcome-and-the-effect-of-different-perpetrators-a-vignette-study
#15
Karen A Sullivan, Christina Wade
Few studies have examined the effect of varying the assault perpetrator on expectations of outcome from mild TBI. Using a cross sectional between groups design, individuals with no history of mild TBI were randomly allocated to one of two vignette conditions. The vignette depicted a mild TBI with fixed injury parameters and a different assault perpetrator (partner, n = 27; or stranger, n = 27). The participants were instructed to imagine that they had been injured as per the depiction, and then to anticipate the injury consequences 6-months later...
September 7, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28879082/hemodynamic-variability-in-soldiers-with-trauma-implications-for-functional-mri-connectivity-studies
#16
D Rangaprakash, Michael N Dretsch, Wenjing Yan, Jeffrey S Katz, Thomas S Denney, Gopikrishna Deshpande
Functional MRI (fMRI) is an indirect measure of neural activity as a result of the convolution of the hemodynamic response function (HRF) and latent (unmeasured) neural activity. Recent studies have shown variability of HRF across brain regions (intra-subject spatial variability) and between subjects (inter-subject variability). Ignoring this HRF variability during data analysis could impair the reliability of such fMRI results. Using whole-brain resting-state fMRI (rs-fMRI), we employed hemodynamic deconvolution to estimate voxel-wise HRF...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28876149/acute-post-concussive-symptoms-in-young-children
#17
Coco Bernard, Audrey McKinlay, David Krieser, Renee Testa, And Jennie Ponsford
OBJECTIVES: Despite peaks of mild traumatic brain injury (mTBI) incidence in young children, few studies have examined the nature of post-concussive symptoms (PCSs) in children under the age of eight, whilst controlling for pre-injury symptoms and effects of trauma. The current study aimed to identify which PCSs differentiate children with mTBI from trauma controls early post-injury, and whether these differed among preschool and school-aged children. METHODS: The sample comprised 101 children aged 2-12 presenting to an emergency department, with concussion or other minor bodily injury (control)...
September 6, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28876146/effects-of-concomitant-mild-traumatic-brain-injury-on-resuming-work-after-suffering-from-an-isolated-limb-fracture-a-cohort-study
#18
Marianne Jodoin, Dominique M Rouleau, Camille Larson-Dupuis, Benoit Benoit, Stéphane Leduc, G-Yves Laflamme, Nadia Gosselin, Meriem Sabir, Louis De Beaumont
BACKGROUND: The objective is to explore the effects of concomitant mild traumatic brain injury (mTBI) on return to work (RTW), among patients suffering from an isolated limb fracture. This follow-up study included a total of 170 working age subjects with an isolated limb fracture, and was conducted in a phone interview approximately 1-year post trauma. 41 had experienced an mTBI and 129 did not. METHODS: Data were obtained through a phone interview conducted on average 20...
September 6, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28875887/the-spectrum-and-outcome-of-paediatric-traumatic-brain-injury-in-kwazulu-natal-province-south-africa-has-not-changed-over-the-last-two-decades
#19
J J P Buitendag, V Y Kong, J L Bruce, G L Laing, D L Clarke, P Brysiewicz
OBJECTIVES: This retrospective review of a prospectively entered and maintained hybrid electronic trauma registry was intended to develop a comprehensive overview of traumatic brain injury (TBI) in children and adolescents and to compare it with previous audits from our local environment and from other developing world centres. All TBI patients admitted to hospital were included in this study. We reviewed the age, gender, outcomes, radiological findings and treatment of the patients. METHODS: All patients aged ≤18 years old who were admitted by the Pietermaritzburg Metropolitan Trauma Service (PMTS) with TBI between December 2012 and December 2016 were included in this audit...
August 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28874926/craniosacral-therapy-and-visceral-manipulation-a-new-treatment-intervention-for-concussion-recovery
#20
Gail Wetzler, Melinda Roland, Sally Fryer-Dietz, Dee Dettmann-Ahern
Background: Military service members and veterans face health issues related to traumatic brain injury (TBI), especially during combat, use of heavy equipment, and exposures to environmental hazards and explosives. There were 400,000 TBIs reported in deployed U.S. troops in 2012. Athletes are also subject to TBI. Studies have indicated that some manual therapies could be helpful for treating patients who have post-concussive syndrome. Objective: This case series report describes the effects of CranioSacral Therapy (CST), Visceral Manipulation (VM), and Neural Manipulation (NM) modalities for treating patients who have post-concussion syndrome...
August 1, 2017: Medical Acupuncture
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