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https://www.readbyqxmd.com/read/29756290/a-standardized-closed-loop-system-for-monitoring-pediatric-tracheostomy-related-adverse-events
#1
Mallory McKeon, Daphne Munhall, Brian K Walsh, Roger Nuss, Reza Rahbar, Mark Volk, Karen Watters
OBJECTIVES/HYPOTHESIS: Advancement in neonatal and pediatric intensive care has increased the need for chronic-care interventions, including tracheostomy. It is well established that children with a tracheostomy are at a high risk for adverse events, many of which are preventable. Despite this, there is no standardized method of monitoring tracheostomy-related adverse events (TRAEs). Our objective was to describe and assess a standardized, closed-loop system for monitoring TRAEs. STUDY DESIGN: Prospective Study...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29742617/cancer-risk-among-children-undergoing-renal-replacement-therapy-results-from-the-israel-national-renal-replacement-therapy-registry-1990-2012
#2
Naama Nuss, Carmit Libruder, Rita Dichtiar, Talia Weinstein, Lital Keinan-Boker, Tamy Shohat, Eliezer Golan
BACKGROUND: Patients with end-stage renal disease who undergo chronic renal replacement therapy (RRT) have a higher incidence of cancer. A limited number of studies addressed the risk for cancer in children exposed to RRT. The purpose of the present study was to examine whether children undergoing RRT in Israel are at increased risk for all-site and specific cancers. SUBJECTS AND METHODS: The study population comprised 674 children aged 0 to 19 years who were registered between January 1990 and December 2012 in the Israel National Renal Replacement Therapy Registry...
May 8, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29719984/the-usefulness-of-a-trans-illuminated-introducer-during-the-nuss-procedure
#3
In-Hag Song, Seung Jin Lee, Seock Yeol Lee
Background There has been an increase in the number of patients undergoing the Nuss procedure for cosmetic purposes, thus increasing the need for safer surgery. However, there are reports of massive hemorrhage and organ damage during the Nuss procedure which involves dissection of the anterior mediastinum. We have developed the trans-illuminated introducer that allows safe surgery while maintaining a small surgical incision of less than 1 cm. Methods This study was a retrospective review of 306 patients aged 3-40 years who underwent the Nuss procedure using the trans-illuminated introducer at our hospital between April 2006 and December 2014...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29716732/different-nuss-procedures-and-risk-management-for-pectus-excavatum-after-surgery-for-congenital-heart-disease
#4
Chenghao Chen, Xiaofeng Li, Na Zhang, Jie Yu, Dong Yan, Changqi Xu, Qi Zeng, Zhongzhi Li
PURPOSE: In Nuss procedure for pectus excavatum (PE) after surgery for congenital heart disease (CHD), retrosternal adhesion may increase the risk of cardiac injury. This study aimed to explore different Nuss procedures and their implications for reducing the incidence of serious complications and improving surgical safety. METHODS: We retrospectively reviewed 49 cases (29 male and 20 female) of Nuss procedures for PE after surgery for CHD that were performed between April 2003 and December 2016...
April 7, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29682380/lung-middle-lobe-laceration-needing-lobectomy-as-complication-of-nuss-bar-removal
#5
Brice Henry, Valérie Lacroix, Thierry Pirotte, Pierre-Louis Docquier
Minimally invasive procedure for the treatment of pectus excavatum as described by Nuss has been used from 1987. The bar initially introduced blindly is now introduced under thoracoscopic control to increase safety of the procedure. It is usually removed two to three years after its insertion in a one-day procedure. Complications of the bar removal are rare but potentially serious. We report the case of a serious complication which occurred immediately after the Nuss bar removal. A 15-year-old boy underwent a Nuss procedure for a severe pectus excavatum without relevant complication...
2018: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29681955/ropivacaine-has-no-advantage-over-bupivacaine-in-thoracic-epidural-analgesia-for-patients-with-pectus-excavatum-undergoing-the-nuss-procedure-a-single-blind-randomized-clinical-trial-comparing-efficacy-and-safety
#6
Małgorzata Walaszczyk, Rafał Wiench, Maja Copik, Jacek Karpe, Małgorzata Łowicka, Anna Pióro, Piotr Knapik, Hanna Misiołek
Introduction: Pectus excavatum repair (Nuss procedure) is a painful procedure requiring effective postoperative analgesia. Aim: To establish whether thoracic epidural analgesia with ropivacaine is non-inferior to epidural analgesia with bupivacaine following the Nuss procedure in children. Material and methods: The prospective, randomized, controlled, single blind study included 81 children. Computer-generated random numbers were used to allocate treatment...
March 2018: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29674896/deep-intraspecific-dna-barcode-splits-and-hybridisation-in-the-udea-alpinalis-group-insecta-lepidoptera-crambidae-an-integrative-revision
#7
Richard Mally, Peter Huemer, Matthias Nuss
The analysis of mitochondrial COI data for the European-Centroasian montane Udea alpinalis species group finds deep intraspecific splits. Specimens of U. austriacalis and U. rhododendronalis separate into several biogeographical groups. These allopatric groups are not recovered in the analyses of the two nuclear markers wingless and Elongation factor 1-alpha, except for U. austriacalis from the Pyrenees and the French Massif Central. The latter populations are also morphologically distinct and conspecific with Scopula donzelalis Guenée, 1854, which is removed from synonymy and reinstated as Udea donzelalis (Guenée, 1854) stat...
2018: ZooKeys
https://www.readbyqxmd.com/read/29672193/cryoanalgesia-in-patients-undergoing-nuss-repair-of-pectus-excavatum-technique-modification-and-early-results
#8
Nicole Morikawa, Nicole Laferriere, Sylvia Koo, Sidney Johnson, Russell Woo, Devin Puapong
PURPOSE: The Nuss procedure for surgical correction of pectus excavatum often causes severe postoperative pain. Cryoanalgesia of intercostal nerves is an alternative modality for pain control. We describe our modification of the cryoICE™ probe that allows for nerve ablation through the ipsilateral chest along with early results utilizing this technique. METHODS: To allow for ipsilateral nerve ablation, a 20-French chest tube was cut and secured to the cryoICE probe, thus providing insulation for the malleable end of the probe...
April 19, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29649225/insulin-receptor-knockdown-blocks-filarial-parasite-development-and-alters-egg-production-in-the-southern-house-mosquito-culex-quinquefasciatus
#9
Andrew Bradley Nuss, Mark R Brown, Upadhyayula Suryanarayana Murty, Monika Gulia-Nuss
Lymphatic filariasis, commonly known as elephantiasis, is a painful and profoundly disfiguring disease. Wuchreria bancrofti (Wb) is responsible for >90% of infections and the remainder are caused by Brugia spp. Mosquitoes of the genera Culex (in urban and semi-urban areas), Anopheles (in rural areas of Africa and elsewhere), and Aedes (in Pacific islands) are the major vectors of W. bancrofti. A preventive chemotherapy called mass drug administration (MDA), including albendazole with ivermectin or diethylcarbamazine citrate (DEC) is used in endemic areas...
April 12, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29644376/sr-5-os-3-o-13-a-mixed-valence-osmium-v-vi-layered-perovskite-variant-exhibiting-temperature-dependent-charge-distribution
#10
Shrikant A Mohitkar, Jürgen Nuss, Henning A Höppe, Claudia Felser, Martin Jansen
New Sr5Os3O13, as synthesized from binary constituents, exhibits several uncommon features. Its crystal structure is dominated by quasi-2D poly-oxoanions that correspond to unprecedented cutouts of the perovskite type of structure, where corner sharing (OsO6) octahedra aggregate to form terraced slabs. The Os5+/Os6+ mixed valence oxide displays a particular charge ordering scheme. One osmium atom (Os1) per formula unit is in the valence state of 5+ in the whole temperature range studied, while the two remaining sites (Os2A and Os2B) show full charge disorder at high temperatures, resulting in an average charge of 5...
April 12, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29643965/video-assisted-thoracoscopic-surgery-in-left-to-right-nuss-procedure-for-pectus-excavatum-for-prevention-of-serious-complications-technical-aspects-based-on-1006-patients
#11
Krystian Pawlak, Łukasz Gąsiorowski, Piotr Gabryel, Wojciech Dyszkiewicz
Introduction: Additional use of the video-assisted thoracoscopic surgery (VATS) technique in the Nuss procedure has been globally accepted for the improvement of safety of surgical treatment as well as for decreased frequency of serious intraoperative and postoperative complications. Aim: To evaluate VATS in surgical treatment of patients with pectus excavatum by the left-to-right Nuss procedure for prevention of serious intra- and postoperative complications. Material and methods: From 2002 to 2016, 1006 patients with pectus excavatum aged 7 to 62 years (mean: 18...
March 2018: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/29627175/multivariate-analysis-of-risk-factors-for-nuss-bar-infections-a-single-center-study
#12
Robert J Obermeyer, Nina S Cohen, Sheema Gaffar, Robert E Kelly, M Ann Kuhn, Frazier W Frantz, Margaret M McGuire, James F Paulson
BACKGROUND/PURPOSE: Our previously published data suggested several risk factors for infection after the Nuss procedure. We aimed to further elucidate these findings. METHODS: An IRB-approved (14-03-WC-0034), single institution, retrospective review was performed to evaluate the incidence of postoperative Nuss bar infections associated with seven variables. These were subjected to bivariate and multivariable analyses. A broad definition of infection was used including cellulitis, superficial infection with drainage, or deep infection occurring at any time postoperatively...
March 8, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29618472/angiotensin-ii-type-1-receptor-autoantibodies-in-postural-tachycardia-syndrome
#13
Xichun Yu, Hongliang Li, Taylor A Murphy, Zachary Nuss, Jonathan Liles, Campbell Liles, Christopher E Aston, Satish R Raj, Artur Fedorowski, David C Kem
BACKGROUND: Both the adrenergic and renin-angiotensin systems contribute to orthostatic circulatory homeostasis, which is impaired in postural orthostatic tachycardia syndrome (POTS). Activating autoantibodies to the α1-adrenergic and β1/2-adrenergic receptors have previously been found in sera from patients with POTS. We hypothesized that patients with POTS might also harbor activating autoantibodies to the angiotensin II type 1 receptor (AT1R) independently of antiadrenergic autoimmunity...
April 4, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29608431/postoperative-pain-outcomes-after-nuss-procedures-comparison-of-epidural-analgesia-continuous-infusion-of-local-anesthetic-and-preoperative-self-hypnosis-training
#14
Renee C B Manworren, Matthew N Anderson, Eric D Girard, Kimberly A Ruscher, Ana Maria Verissimo, Hannah Palac, Richard Weiss, Christine Rader, Donald Hight
BACKGROUND/PURPOSE: The Nuss procedure to correct pectus excavatum is associated with severe postoperative pain. The purpose of this retrospective study was to compare pain management outcomes of thoracic epidural analgesia and continuous infusion of local anesthetic (CILA) with and without preoperative self-hypnosis training (SHT) after Nuss procedure (4 treatment groups). METHODS: Between February 2010 and December 2013, 24 of 53 adolescents who underwent Nuss procedure received SHT...
April 2, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29607200/initial-experience-with-a-3d-printed-model-for-preoperative-simulation-of-the-nuss-procedure-for-pectus-excavatum
#15
Naoto Matsuo, Keitaro Matsumoto, Yasuaki Taura, Yuka Sakakibara, Daisuke Taniguchi, Katsunori Takagi, Yusuke Yamane, Masayuki Obatake, Naoya Yamasaki, Takeshi Nagayasu
The incidence of pectus excavatum has been estimated to be between 0.1% and 0.8% though a large autopsy series reports. After publication of the Nuss procedure for pectus excavatum, it became widely accepted. However, there are still some complications, such as over-correction and recurrence. To reduce differences in the procedure due to surgeons' experience level, preoperative simulation may be useful. Thus, we performed simulated surgery using a specific patient's three-dimensional (3D) chest wall model made by a 3D printer before operation...
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29600099/massive-pericardial-effusion-after-nuss-procedure-to-drain-or-not-to-drain
#16
Peter S Y Yu, Vikki W K Ng, Rainbow W H Lau, Calvin S H Ng
A 11-year-old boy presented with refractory fever and dyspnoea after Nuss procedure. Massive pericardial effusion was detected on computer tomography scan performed under corticosteroid cover for his asthmatic history. With rapid clinical improvement following corticosteroids, a clinical diagnosis of post-pericardiotomy syndrome (PPS) was made. Following a course of oral prednisolone, serial blood test and echocardiogram showed gradual resolution of inflammation and pericardial effusion. This rarely-reported case serves as a poignant reminder to PPS after Nuss procedure as a cause of febrile massive pericardial effusion...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29575173/vascular-supply-of-the-femoral-head-in-sheep-implications-for-the-ovine-femoroacetabular-impingement-model
#17
Moritz Tannast, Nadja Wolfer, Michael K Ryan, Katja M Nuss, Brigitte von Rechenberg, Simon D Steppacher
Sheep hips have a natural non-spherical head similar to a cam-type deformity in human beings. By performing an intertrochanteric varus osteotomy, cam-type femoroacetabular impingement can be induced experimentally. In sheep, the aspherical portion is located superiorly-exactly matching the region where the superior retinacular vessels enter the femoral head-neck junction in human beings. In order to fully exploit the potential of this experimental FAI model, a safe osteochondroplasty of the superior asphericity would need to be done without the risk of avascular necrosis...
March 25, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29550038/changes-in-resting-pulmonary-function-testing-over-time-after-the-nuss-procedure-a-systematic-review-and-meta-analysis
#18
REVIEW
Quan Wang, Shulei Fan, Chun Wu, Xianqing Jin, Zhengxia Pan, Daqing Hong
BACKGROUND: Pectus excavatum, the most common congenital chest wall deformity in pediatric patients, leads to pulmonary dysfunction. There is no consensus regarding the effectiveness of the Nuss procedure for recovering pulmonary function. In this meta- analysis, we focused on the changes that occur in pulmonary function after the Nuss procedure. METHODS: We performed a literature search in the MEDLINE, Embase, Cochrane library and PubMed databases. The included studies were required to contain pulmonary function tests with results adjusted to predicted values both before and after the Nuss procedure...
February 21, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29544705/gene-expression-profiling-of-low-grade-endometrial-stromal-sarcoma-indicates-fusion-protein-mediated-activation-of-the-wnt-signaling-pathway
#19
Joanna Przybyl, Lukasz Kidzinski, Trevor Hastie, Maria Debiec-Rychter, Roel Nusse, Matt van de Rijn
OBJECTIVE: Low-grade endometrial stromal sarcomas (LGESS) harbor chromosomal translocations that affect proteins associated with chromatin remodeling Polycomb Repressive Complex 2 (PRC2), including SUZ12, PHF1 and EPC1. Roughly half of LGESS also demonstrate nuclear accumulation of β-catenin, which is a hallmark of Wnt signaling activation. However, the targets affected by the fusion proteins and the role of Wnt signaling in the pathogenesis of these tumors remain largely unknown. METHODS: Here we report the results of a meta-analysis of three independent gene expression profiling studies on LGESS and immunohistochemical evaluation of nuclear expression of β-catenin and Lef1 in 112 uterine sarcoma specimens obtained from 20 LGESS and 89 LMS patients...
March 12, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29543638/patch-testing-for-the-evaluation-of-metal-hypersensitivity-in-the-nuss-procedure-a-review-of-the-literature
#20
Annika Selvick, Rita Lloyd
The Nuss procedure has become the predominant reason for the use of metal implants by pediatric general and thoracic surgeons. Current guidelines recommend preimplant testing for all patients undergoing the Nuss procedure, which differs from the guidelines for all other orthopedic procedures. This review was done to further evaluate this discrepancy.
February 28, 2018: Dermatitis
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