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https://www.readbyqxmd.com/read/29663676/a-single-center-pilot-study-evaluating-a-novel-trihex-peptide-and-botanical-containing-eye-treatment-compared-to-baseline
#1
Alex Reivitis, Kian Karimi, Chester Griffiths, Ashley Banayan
BACKGROUND: Topical treatments containing tripeptide and hexapeptide (TriHex technology) have been proven to contribute to youthful skin by clearing the extracellular matrix and stimulating collagen and elastin production. OBJECTIVE: Evaluate the efficacy of a novel eye treatment containing TriHex peptides and other synergistic ingredients for the daily treatment of fine lines/crow's feet around the eyes, under eye hollowing, under eye bags, and dark circles. PATIENTS/METHODS: In this study, 10 subjects (9 female and 1 male) aged 30-60 of Fitzpatrick skin type I, II, or III were selected to use an eye treatment containing TriHex peptides and active botanicals (Alastin Restorative Eye Treatment with TriHex Technology™, ALASTIN Skincare, Inc...
April 16, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29596731/prevention-and-treatment-of-diaper-dermatitis
#2
Ulrike Blume-Peytavi, Varvara Kanti
Diaper dermatitis (DD) is one of the most common skin conditions that infants suffer from and their caregivers manage in the first months post-birth. As such, questions of effective prevention and treatment of the condition often arise. Nonmedical skincare practices that support healthy skin barrier function can prevent DD manifestation or alleviate the condition in many cases. The usage of barrier emollients and improved diaper technology contributes to keeping moisture and irritants away from an infant's delicate skin...
March 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29577991/the-effect-of-an-exfoliating-skincare-regimen-on-the-numbers-of-epithelial-squames-on-the-skin-of-operating-theatre-staff-studied-by-surface-microscopy
#3
A G Wernham, O L Cain, A M Thomas
BACKGROUND: The shedding of epithelial squames (skin scales) by staff in operating theatre air is an important source for deep infection following joint replacement surgery. This is a serious complication resulting in significant morbidity for the patient and substantial cost implications for healthcare systems. Much effort has been put into providing clean-air in operating theatres, yet little attention has been given to reducing the shedding of surface skin scales at source. AIM: Our aim was to develop a novel method for calculating surface skin scale density using surface microscopy and to use it to evaluate the effect of a skin care regimen on operating theatre staff...
March 22, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29542253/facile-preparation-of-magnetic-molecularly-imprinted-polymers-for-the-selective-extraction-and-determination-of-dexamethasone-in-skincare-cosmetics-using-hplc
#4
Wei Du, Bilin Zhang, Pengqi Guo, Guoning Chen, Chun Chang, Qiang Fu
Dexamethasone-imprinted polymers were fabricated by reversible addition fragmentation chain transfer polymerization on the surface of magnetic nanoparticles under mild polymerization conditions, which exhibited a narrow polydispersity and high selectivity for dexamethasone extraction. The dexamethasone-imprinted polymers were characterized by scanning electron microscopy, transmission electron microscope, Fourier transform infrared spectroscopy, X-ray diffraction, energy dispersive spectrometry and vibrating sample magnetometry...
March 15, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29537448/addressing-male-facial-skin-concerns-clinical-efficacy-of-a-topical-skincare-treatment-product-for-men
#5
Elizabeth T Makino, Lily I Jiang, Priscilla Tan, Tsing Cheng, Rahul C Mehta
The growing male skincare market reflects the increased interest of men in addressing facial aging concerns and maintaining a healthy youthful appearance. Because of differences in skin structure and aging as well as in lifestyle and behavior, male facial skin presents unique challenges that may result in different priorities or treatment strategies compared to female skin. A clinical study was conducted to assess clinical efficacy and tolerability of a topical skincare treatment product that was developed to address several male facial skin concerns related to skin quality, skin aging, and shaving...
March 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29526880/emu-oil-reduces-lps-induced-production-of-nitric-oxide-and-tnf-%C3%AE-but-not-phagocytosis-in-raw-264-macrophages
#6
Tadayoshi Miyashita, Kazuhiro Minami, Minoru Ito, Ryosuke Koizumi, Yoshimasa Sagane, Toshihiro Watanabe, Koichi Niwa
Emu is the second-largest extant bird native to Australia. Emu oil, obtained from the emu's fat deposits, is used as an ingredient in cosmetic skincare products. Emu oil has been reported to improve several inflammatory symptoms; however, the mechanisms of these anti-inflammatory effects are largely unknown. This study investigated the effects of emu oil on the inflammatory macrophage response in vitro. A murine macrophage cell line, RAW 264, was incubated in culture media supplemented with or without emu oil and stimulated with lipopolysaccharide (LPS)...
March 9, 2018: Journal of Oleo Science
https://www.readbyqxmd.com/read/29493714/prevention-of-hand-eczema-effect-of-an-educational-program-versus-treatment-as-usual-results-of-the-randomized-clinical-prevex-trial
#7
Maja H Fisker, Niels E Ebbehøj, Søren Grove Vejlstrup, Jane Lindschou, Christian Gluud, Per Winkel, Jens Peter Bonde, Tove Agner
Objective Occupational hand eczema has adverse health and socioeconomic impacts for the afflicted individuals and society. Prevention and treatment strategies are needed. This study aimed to assess the effectiveness of an educational intervention on sickness absence, quality of life and severity of hand eczema. Methods PREVEX (PreVention of EXema) is an individually randomized, parallel-group superiority trial investigating the pros and cons of one-time, 2-hour, group-based education in skin-protective behavior versus treatment as usual among patients with newly notified occupational hand eczema, with follow-up after one year...
March 1, 2018: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/29470423/3-5-6-7-8-3-4-heptamethoxyflavone-a-citrus-flavonoid-inhibits-collagenase-activity-and-induces-type-i-procollagen-synthesis-in-hdfn-cells
#8
Hong-Il Kim, Yong-Un Jeong, Jong-Hyeon Kim, Young-Jin Park
Citrus fruits contain various types of flavonoids with powerful anti-aging and photoprotective effects on the skin, and have thus been attracting attention as potential, efficacious skincare agents. Here, we aimed to investigate the chemical composition of Citrus unshiu and its protective effects on photoaging. We isolated and identified a bioactive compound, 3,5,6,7,8,3',4'-heptamethoxyflavone (HMF), from C. unshiu peels using ethanol extraction and hexane fractionation. HMF inhibited collagenase activity and increased type I procollagen content in UV-induced human dermal fibroblast neonatal (HDFn) cells...
February 22, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29467107/associations-between-personal-care-product-use-patterns-and-breast-cancer-risk-among-white-and-black-women-in-the-sister-study
#9
Kyla W Taylor, Melissa A Troester, Amy H Herring, Lawrence S Engel, Hazel B Nichols, Dale P Sandler, Donna D Baird
BACKGROUND: Many personal care products include chemicals that might act as endocrine disruptors and thus increase the risk of breast cancer. OBJECTIVE: We examined the association between usage patterns of beauty, hair, and skin-related personal care products and breast cancer incidence in the Sister Study, a national prospective cohort study (enrollment 2003-2009). METHODS: Non-Hispanic black (4,452) and white women (n=42,453) were examined separately using latent class analysis (LCA) to identify groups of individuals with similar patterns of self-reported product use in three categories (beauty, skin, hair)...
February 21, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29450142/arborvitae-thuja-plicata-essential-oil-significantly-inhibited-critical-inflammation-and-tissue-remodeling-related-proteins-and-genes-in-human-dermal-fibroblasts
#10
Xuesheng Han, Tory L Parker
Arborvitae ( Thuja plicata ) essential oil (AEO) is becoming increasingly popular in skincare, although its biological activity in human skin cells has not been investigated. Therefore, we sought to study AEO's effect on 17 important protein biomarkers that are closely related to inflammation and tissue remodeling by using a pre-inflamed human dermal fibroblast culture model. AEO significantly inhibited the expression of vascular cell adhesion molecule 1 (VCAM-1), intracellular cell adhesion molecule 1 (ICAM-1), interferon gamma-induced protein 10 (IP-10), interferon-inducible T-cell chemoattractant (I-TAC), monokine induced by interferon gamma (MIG), and macrophage colony-stimulating factor (M-CSF)...
June 2017: Biochimie Open
https://www.readbyqxmd.com/read/29421853/anti-photoaging-effect-of-prunus-yeonesis-blossom-extract-via-inhibition-of-mapk-ap-1-and-regulation-of-the-tgf-%C3%AE-i-smad-and-nrf2-are-signaling-pathways
#11
Lu Li, Eunson Hwang, Hien T T Ngo, Pei Lin, Wei Gao, Ying Liu, Tae-Hoo Yi
Cherry blossoms have attracted attention as an ingredient with potential for use in skincare products. However, no skin photoaging-related research has been performed with this plant. In the present study, cherry blossom extract (CBE) at 1, 10, and 100 μg/mL was investigated for its skin anti-photoaging effects in UVB-irradiated normal human dermal fibroblasts (NHDF) cells in vitro. Our results showed that CBE markedly increased type I procollagen during UVB exposure via two pathways. Firstly, transcription activator protein-1 expression and MAP kinases were downregulated, consequently reducing the production of matrix metalloproteinase (MMP)-1 and MMP-3...
February 8, 2018: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29384713/taking-a-proactive-approach-to-mild-to-moderate-chronic-oedema-a-case-study
#12
Diane Jehu, Linda Jenkins, Karen Morgan, Melanie J Thomas
This case study demonstrates the benefits of early intervention and a proactive approach for a patient with chronic oedema living in the community. These benefited the patient and also supported value-based healthcare in the NHS. The patient's health and wellbeing significantly improved with an assessment of his chronic oedema and a management plan consisting of skincare, an exercise and movement programme and the introduction of a class 1 British standard compression garment.
February 2, 2018: British Journal of Community Nursing
https://www.readbyqxmd.com/read/29164778/open-label-study-assessing-the-efficacy-and-tolerability-of-topical-skincare-and-sun-protection-products-following-intense-pulsed-light-treatment
#13
Isabela T Jones, Isabella Guiha, Sabrina G Fabi
BACKGROUND: The visible signs of photodamage can be improved by intense pulsed light (IPL). Active ingredients in cosmeceuticals also have effects on skin quality and pigmentation, and can camouflage post-treatment side effects. Combination therapies utilizing different treatment modalities have been shown to optimize clinical outcomes for skin rejuvenation and patient satisfaction. AIM: To evaluate the efficacy of a combination of IPL with a daily topical skincare and sunscreen regimen for the treatment of facial photodamage and for the improvement of IPL treatment tolerability...
November 21, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29142178/actual-consumption-amount-of-personal-care-products-reflecting-japanese-cosmetic-habits
#14
Masahiko Yamaguchi, Daisuke Araki, Takeshi Kanamori, Yasuko Okiyama, Hirokazu Seto, Masaki Uda, Masahito Usami, Yutaka Yamamoto, Takuji Masunaga, Hitoshi Sasa
Safety assessments of cosmetics are carried out by identifying possible harmful effects of substances in cosmetic products and assessing the exposure to products containing these substances. The present study provided data on the amounts of cosmetic products consumed in Japan to enhance and complement the existing data from Europe and the United States, i.e., the West. The outcomes of this study increase the accuracy of exposure assessments and enable more sophisticated risk assessment as a part of the safety assessment of cosmetic products...
2017: Journal of Toxicological Sciences
https://www.readbyqxmd.com/read/29141061/a-randomized-investigator-blinded-comparison-of-two-topical-regimens-in-fitzpatrick-skin-types-iii-vi-with-moderate-to-severe-facial-hyperpigmentation
#15
Monique J Vanaman Wilson, Isabela T Jones, Joanna Bolton, Lisa Larsen, Douglas C Wu, Mitchel P Goldman
<p>Purpose: Though hydroquinone (HQ) remains the gold standard for treatment of hyperpigmentation, concerns about its safety have prompted the development of HQ-free topical skin lightening systems. OBJECTIVE: To compare the efficacy and tolerability of a new HQ-free system and a popular HQ-based system for the improvement of facial hyperpigmentation and photoaging in darker skin types. METHODS: This investigator-blinded trial randomized 30 subjects of Fitzpatrick skin types III to VI with moderate to severe hyperpigmentation to a new 7-product HQ-free system or a 7-product HQ-based system for 12 weeks...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29139362/efficacy-and-tolerability-of-a-twice-daily-three-step-men-s-skincare-regimen-in-improving-overall-skin-quality-and-reducing-shave-related-irritation
#16
Katie Rodan, Kathy Fields, Timothy J Falla
More men are beginning to take advantage of opportunities to improve the health and appearance of their skin; however, the effectiveness of men's skincare regimens has not been well studied. The authors investigated the efficacy and tolerance of a twice-daily, three-step men's skincare regimen in improving skin appearance and reducing shave-related issues. Twenty-nine men who used a wet-shaving method completed a specific, three-step, twice-daily facial regimen-a Shave Cleanser, a Post-Shave Treatment, and Day Protection-in place of their usual routine for 4 weeks...
2017: Skinmed
https://www.readbyqxmd.com/read/29067717/haptic-augmented-skin-surface-generation-toward-telepalpation-from-a-mobile-skin-image
#17
K Kim
BACKGROUND/PURPOSE: Very little is known about the methods of integrating palpation techniques to existing mobile teleskin imaging that delivers low quality tactile information (roughness) for telepalpation. However, no study has been reported yet regarding telehaptic palpation using mobile phone images for teledermatology or teleconsultations of skincare. METHODS: This study is therefore aimed at introducing a new algorithm accurately reconstructing a haptic augmented skin surface for telehaptic palpation using a low-cost clip-on microscope simply attached to a mobile phone...
October 25, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28983938/effects-of-moisturizing-skincare-on-skin-barrier-function-and-the-prevention-of-skin-problems-in-3-month-old-infants-a-randomized-controlled-trial
#18
Kaori Yonezawa, Megumi Haruna, Masayo Matsuzaki, Mie Shiraishi, Reiji Kojima
An effective newborn skincare protocol has not been established. We aimed to evaluate the effects of moisturizing skincare, including using lotion and reducing routine bathing. Our hypothesis was that moisturizing skincare would improve skin barrier function. This randomized controlled trial included 227 healthy Asian newborns between 1 week and 3 months old. We compared moisturizing skincare (bathing every 2 days and using lotion daily; intervention, n = 113) to daily bathing without lotion (control, n = 114)...
January 2018: Journal of Dermatology
https://www.readbyqxmd.com/read/28963772/bacterial-cellulose-skin-masks-properties-and-sensory-tests
#19
Guilherme Pacheco, Carolina Véspoli de Mello, Bruna Galdorfini Chiari-Andréo, Vera Lucia Borges Isaac, Sidney José Lima Ribeiro, Édison Pecoraro, Eliane Trovatti
BACKGROUND: Bacterial cellulose (BC) is a versatile material produced by microorganisms in the form of a membranous hydrogel, totally biocompatible, and endowed with high mechanical strength. Its high water-holding capacity based on its highly porous nanofibrillar structure allows BC to incorporate and to release substances very fast, thus being suitable for the preparation of skincare masks. AIMS: The preparation and characterization of cosmetic masks based on BC membranes and active cosmetics...
September 29, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28961169/anti-inflammatory-thioredoxin-family-proteins-for-medicare-healthcare-and-aging-care
#20
REVIEW
Junji Yodoi, Yoshiyuki Matsuo, Hai Tian, Hiroshi Masutani, Takashi Inamoto
Human thioredoxin (TRX) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys-, which is induced by biological stress due to oxidative damage, metabolic dysfunction, chemicals, infection/inflammation, irradiation, or hypoxia/ischemia-reperfusion. Our research has demonstrated that exogenous TRX is effective in a wide variety of inflammatory diseases, including viral pneumonia, acute lung injury, gastric injury, and dermatitis, as well as in the prevention and amelioration of food allergies...
September 29, 2017: Nutrients
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