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https://www.readbyqxmd.com/read/28183235/cactus-cladodes-opuntia-humifusa-extract-minimizes-the-effects-of-uv-irradiation-on-keratinocytes-and-hairless-mice
#1
Kyungmi Park, Hyeon-Son Choi, Yang Hee Hong, Eun Young Jung, Hyung Joo Suh
CONTEXT: Cactus cladodes [Opuntia humifusa (Raf.) Raf. (Cactaceae)] is one of the cactus genera, which has long been used as a folk medicine for skin disorders. OBJECTIVE: This study investigated the skincare potential of cactus cladodes extract (OHE), including its ability to regulate ultraviolet B (UVB)-induced hyaluronic acid (HA) production. MATERIALS AND METHODS: Gene expression levels of hyaluronic acid synthases (HASs) and hyaluronidase (HYAL) were measured in UVB-irradiated HaCaT cells with OHE treatment (10, 25, 50, 100 μg/mL) by real-time polymerase chain reaction (PCR)...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28133878/acne-ra-1-2-a-novel-uv-selective-face-cream-for-patients-with-acne-efficacy-and-tolerability-results-of-a-randomized-placebo-controlled-clinical-study
#2
Enza Cestone, Angela Michelotti, Valentina Zanoletti, Andrea Zanardi, Raffaella Mantegazza, Maurizia Dossena
BACKGROUND: General skincare measures such as the use of moisturisers and products containing adequate photoprotection are important components of acne patients' management to complement the pharmacological regimen. Acne RA-1,2 is a novel dermato-cosmetic product which contains selective photofilters and active ingredients against the multifactorial pathophysiology of acne. OBJECTIVES: To evaluate the tolerability of Acne RA-1,2 and its effect on the clinical signs of acne...
January 29, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28120835/associations-among-personal-care-product-use-patterns-and-exogenous-hormone-use-in-the-niehs-sister-study
#3
Kyla W Taylor, Donna D Baird, Amy H Herring, Lawrence S Engel, Hazel B Nichols, Dale P Sandler, Melissa A Troester
It is hypothesized that certain chemicals in personal care products may alter the risk of adverse health outcomes. The primary aim of this study was to use a data-centered approach to classify complex patterns of exposure to personal care products and to understand how these patterns vary according to use of exogenous hormone exposures, oral contraceptives (OCs) and post-menopausal hormone therapy (HT). The NIEHS Sister Study is a prospective cohort study of 50,884 US women. Limiting the sample to non-Hispanic blacks and whites (N=47,019), latent class analysis (LCA) was used to identify groups of individuals with similar patterns of personal care product use based on responses to 48 survey questions...
January 25, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28115862/efficacy-of-a-twice-daily-3-step-over-the-counter-skincare-regimen-for-the-treatment-of-acne-vulgaris
#4
Katie Rodan, Kathy Fields, Timothy J Falla
BACKGROUND: Acne vulgaris (acne) is the most common skin disorder producing physical and emotional scars that can persist for years. An estimated 83% of acne sufferers self-treat, but there is lack of studies documenting the effectiveness of over-the-counter (OTC) acne treatment products. OBJECTIVE: This study was conducted to determine the effectiveness of an OTC, 3-step, anti-acne skincare regimen in treating acne and improving the appearance of red/inflamed facial skin...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28095574/managing-occupational-irritant-contact-dermatitis-using-a-two-step-skincare-regimen-designed-to-prevent-skin-damage-and-support-skin-recovery
#5
Erika C von Grote, Kiruthi Palaniswarmy, Matthew H Meckfessel
Occupational irritant contact dermatitis (ICD) affecting the hands is a common and difficult-to-manage condition. Occupations that necessitate contact with harsh chemicals, use of alcohol-based disinfectants, and frequent hand washing elevate the risk of ICD. Management strategies that do not adequately prevent accumulated damage and repair skin, can develop into chronic dermatoses which negatively impact work productivity and quality of life. A 2-step skin-care regimen (Excipial Daily Protection Hand Cream (EP) and Excipial Rapid Repair Hand Cream (ER), Galderma Laboratories, L...
December 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28095567/evidence-based-skincare-the-importance-of-offering-moisturization-relief-and-protection-in-common-skin-disorders
#6
https://www.readbyqxmd.com/read/28095558/clinical-evaluation-of-a-4-hydroquinone-1-retinol-treatment-regimen-for-improving-melasma-and-photodamage-in-fitzpatrick-skin-types-iii-vi
#7
Marta I Rendon, Sylvia Barkovic
The bene ts of monotherapy with hydroquinone for melasma and retinoids for photodamaged skin is well established. Here we report results of a hydroquinone skincare regimen designed for melasma treatment combined with a cosmetic retinol cream on subjects presenting with both melasma and facial photodamage in a 24-week study. Improvement in melasma and photodamage ef cacy pa- rameters of melasma pigmentation intensity and melasma area and severity index (MASI), as well as overall photodamage and mottled hyperpigmentation were found by week 4, the rst post-baseline time point...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28018771/skincare-bootcamp-the-evolving-role-of-skincare
#8
Katie Rodan, Kathy Fields, George Majewski, Timothy Falla
BACKGROUND: Although cosmetic procedures have a significant impact on certain aspects of aging, such as deep, wrinkling, sagging, and volume loss, they fail to address the overall quality of the skin. METHODS: Daily skincare routines potentially can have a significant long-term impact on the overall quality of a person's complexion. RESULTS: By expanding our product knowledge, we can help our patients individualize their at-home skincare routine using effective products and ingredients designed to address their specific skin concern and support the professional care we deliver...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27760249/multidirectional-in-vivo-characterization-of-skin-using-wiener-nonlinear-stochastic-system-identification-techniques
#9
Matthew D Parker, Lynette A Jones, Ian W Hunter, A J Taberner, M P Nash, P M F Nielsen
A triaxial force-sensitive microrobot was developed to dynamically perturb skin in multiple deformation modes, in vivo. Wiener static nonlinear identification was used to extract the linear dynamics and static nonlinearity of the force-displacement behavior of skin. Stochastic input forces were applied to the volar forearm and thenar eminence of the hand, producing probe tip perturbations in indentation and extension. Wiener static nonlinear approaches increased the variance accounted for by 0.1 % to 3.4 % over linear approaches, to 94 % to 97 %...
October 19, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27602981/the-effects-of-a-daily-skincare-regimen-on-maintaining-the-benefits-obtained-from-previous-chemical-resurfacing-treatments
#10
Suzanne Bruce, Wendy Roberts, Craig Teller, Lora Colvan
BACKGROUND: Chemical peels are versatile treatments that involve chemical exfoliation of the skin for cosmetic improvement. Deeper peels produce more significant results, but can be associated with longer healing time and potential complications. Novel chemical resurfacing treatments (AGE and MELA) were developed in Europe to produce skin resurfacing via controlled inflammation to promote cell regeneration with minimum negative effects associated with conventional peelings. The AGE Resurfacing regimen is indicated for the treatment of photoaging, and consists of multi-ingredient peeling solution with trichloroacetic acid, pyruvic acid, salicylic acid, mandelic acid, and lactobionic acid...
September 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/27602972/an-open-label-clinical-trial-of-a-peptide-treatment-serum-and-supporting-regimen-designed-to-improve-the-appearance-of-aging-facial-skin
#11
Zoe Diana Draelos, Tatiana Kononov, Theresa Fox
A 14-week single-center clinical usage study was conducted to test the efficacy of a peptide treatment serum and supporting skincare regimen in 29 women with mild to moderately photodamaged facial skin. The peptide treatment serum contained gamma-aminobutyric acid (GABA) and various peptides with neurotransmitter inhibiting and cell signaling properties. It was hypothesized that the peptide treatment serum would ameliorate eye and facial expression lines including crow's feet and forehead lines. The efficacy of the supporting skincare regimen was also evaluated...
September 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/27546316/evaluation-of-skin-firmness-by-the-dynaskin-a-novel-non-contact-compression-device-and-its-use-in-revealing-the-efficacy-of-a-skincare-regimen-featuring-a-novel-anti-ageing-ingredient-acetyl-aspartic-acid
#12
E M Kearney, C Messaraa, G Grennan, G Koeller, A Mavon, E Merinville
BACKGROUND: One of the key strategies for anti-ageing in the cosmetics industry today is to target the structural changes responsible for ptosis of the skin, given its impact on age perception. Several objective and non-invasive methods are available to characterise the biomechanical properties of the skin, which are operator-dependent, involving skin contact and providing single-dimensional numerical descriptions of skin behaviour. The research introduces the DynaSKIN, a device using non-contact mechanical pressure in combination with fringe projection to quantify and visualise the skin response in 3-dimensions...
August 21, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27539897/characterization-and-mechanisms-of-photoageing-related-changes-in-skin-damages-of-basement-membrane-and-dermal-structures
#13
REVIEW
Satoshi Amano
Sun-exposed skin is characterized by superficial changes such as wrinkles, sagging and pigmentary changes, and also many internal changes in the structure and function of epidermis, basement membrane (BM) and dermis. These changes (so-called photoageing) are predominantly induced by the ultraviolet (UV) component of sunlight. Epidermis of UV-irradiated skin produced several enzymes such as matrix metalloproteinases (MMPs), urinary plasminogen activator (uPA)/plasmin and heparanase, which degrade dermal collagen fibres and elastic fibres in the dermis, and components of epidermal BM...
August 2016: Experimental Dermatology
https://www.readbyqxmd.com/read/27498661/investigation-of-the-efficacy-of-dr-michaels%C3%A2-soratinex%C3%A2-family-in-maintaining-a-symptom-free-state-for-patients-with-psoriasis-in-remission-a-retrospective-comparative-study
#14
J Hercogovấ, M Fioranelli, S Gianfaldoni, A A Chokoeva, G Tchernev, U Wollina, M Tirant, F Novotny, M G Roccia, G K Maximov, K França, T Lotti
Psoriasis is a chronic inflammatory disease, affecting about 3% of the worldwide population. Although there are many therapeutic options available today for psoriasis, none of them can be considered as the gold standard treatment for maintaining a sustained period of remission. The aim of this study was to investigate whether a maintenance dosage of Michaels® Soratinex® product family is effective in maintaining a symptom-free state for patients in remission. Fifty patients (23 male, 27 female), aged 18-58-years-old (mean age: 38...
April 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27498652/a-european-prospective-randomized-placebo-controlled-doubleblind-study-on-the-efficacy-and-safety-of-dr-michaels%C3%A2-also-branded-as-soratinex%C3%A2-product-family-for-stable-chronic-plaque-psoriasis
#15
K França, J Hercogovấ, M Fioranelli, S Gianfaldoni, A A Chokoeva, G Tchernev, U Wollina, M Tirant, F Novotny, M G Roccia, G K Maximov, T Lotti
Psoriasis is a chronic, inflammatory, recurrent, genetically determined dermatitis that affects the skin and joints. Many patients affected by this condition seek alternatives and complementary treatment options such as herbal medicines. In order to establish the safety of these products, trials, according to medical standards should be performed to provide the highest quality of data. The aim of this study was to assess the efficacy and safety of an Australian series of herbal skincare products [Dr. Michaels® (Soratinex®) skin-care products for psoriasis] for the management of stable chronic plaque psoriasis...
April 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27496663/fifty-years-of-research-and-development-of-cosmeceuticals-a-contemporary-review
#16
REVIEW
Chun-Man Lee
Facial rejuvenation can be categorized into skincare and facial contouring. Research and development of cosmeceuticals is aimed at addressing the major signs of photoaging: wrinkles, dyschromia, and sallowness. Assessment of photoaging comes in clinical and photographic forms; a photonumeric scale developed by Griffiths et al. has been assured of its validity and reliability for the assessment of severity of photoaging in qualitative studies. Treatment of photoaging comes in two categories: preventive and reversal of signs; whilst sunfactors are the most efficient and essential in preventing photodamage, research and development of cosmeceuticals for facial rejuvenation has been robust, thanks to several landmark studies in the last fifty years, funded by some of the forerunners in contemporary cosmetic industry...
December 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27427424/hypersensitivity-pneumonitis-in-a-beautician
#17
Thibaud Soumagne, Gabriel Reboux, Bruno Degano, Jean Charles Dalphin
A 52-year-old non-smoking beautician using a skincare device spraying steam and ozone (a "vapozone" facial steamer) was referred for progressive dyspnea and dry cough during working periods. Although spirometry was normal, she had decreased diffusing capacity of the lung for carbon monoxide, bronchiolitis with air trapping on high-resolution CT scan and 60% lymphocytosis by bronchoalveolar lavage. Twenty-six antigens were tested and serum-specific precipitins were found mainly against Pseudomonas sp. and Mycobacterium mucogenicum...
July 18, 2016: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/27427381/prospective-audit-showing-improved-patient-assessed-skin-toxicity-with-use-of-betamethasone-cream-for-those-at-high-risk-of-radiation-dermatitis
#18
Sara C Erridge, Marie McCabe, Mandy K Porter, Patricia Simpson, Alison L Stillie
This audit was conducted before and after introduction of a risk-based skincare policy with prophylactic steroids recommended for those at high risk. Comparison of the two cohorts confirmed results seen in trials with significant reduction in redness, itch, discomfort, sleep disturbance, and use of analgesia with the addition of steroids.
July 14, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27251017/attractiveness-of-volatiles-from-different-body-parts-to-the-malaria-mosquito-anopheles-coluzzii-is-affected-by-deodorant-compounds
#19
Niels O Verhulst, Berhane T Weldegergis, David Menger, Willem Takken
Mosquitoes display biting preferences among different sites of the human body. In addition to height or convection currents, body odour may play a role in the selection of these biting sites. Previous studies have shown that skin emanations are important host-finding cues for mosquitoes. In this study, skin emanations were collected from armpits, hands and feet; the volatile profiles were analysed and tested for their attractiveness to the malaria mosquito Anopheles coluzzii. Skin emanations collected from armpits were less attractive to An...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27180442/formulation-development-of-topical-cream-loaded-with-ananas-comosus-extract-in-vivo-evaluation-for-changes-in-skin-barrier-function-using-biophysical-techniques
#20
Atif I Arshad, Shoaib H M Khan, Naveed Akhtar
The prime objective of current investigation was to develop a topical skin care cream (w/o) loaded with Ananas comosus extract versus placebo control, and evaluated non-invasively for changes in skin barrier function i.e., epidermal hydration levels and transepidermal water loss (TEWL), on healthy human volunteers. Active cream carrying 2% extract of Ananas comosus in the internal phase of w/o emulsion was prepared while placebo contained no extract. Stability assessment of both creams was performed at various storage conditions 8, 25, 40 degrees C, 40 degrees C + 75% RH (relative humidity) and 50 degrees C...
March 2016: Acta Poloniae Pharmaceutica
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