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https://www.readbyqxmd.com/read/29164778/open-label-study-assessing-the-efficacy-and-tolerability-of-topical-skincare-and-sun-protection-products-following-intense-pulsed-light-treatment
#1
Isabela T Jones, Isabella Guiha, Sabrina G Fabi
BACKGROUND: The visible signs of photodamage can be improved by intense pulsed light (IPL). Active ingredients in cosmeceuticals also have effects on skin quality and pigmentation, and can camouflage post-treatment side effects. Combination therapies utilizing different treatment modalities have been shown to optimize clinical outcomes for skin rejuvenation and patient satisfaction. AIM: To evaluate the efficacy of a combination of IPL with a daily topical skincare and sunscreen regimen for the treatment of facial photodamage and for the improvement of IPL treatment tolerability...
November 21, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29142178/actual-consumption-amount-of-personal-care-products-reflecting-japanese-cosmetic-habits
#2
Masahiko Yamaguchi, Daisuke Araki, Takeshi Kanamori, Yasuko Okiyama, Hirokazu Seto, Masaki Uda, Masahito Usami, Yutaka Yamamoto, Takuji Masunaga, Hitoshi Sasa
Safety assessments of cosmetics are carried out by identifying possible harmful effects of substances in cosmetic products and assessing the exposure to products containing these substances. The present study provided data on the amounts of cosmetic products consumed in Japan to enhance and complement the existing data from Europe and the United States, i.e., the West. The outcomes of this study increase the accuracy of exposure assessments and enable more sophisticated risk assessment as a part of the safety assessment of cosmetic products...
2017: Journal of Toxicological Sciences
https://www.readbyqxmd.com/read/29141061/a-randomized-investigator-blinded-comparison-of-two-topical-regimens-in-fitzpatrick-skin-types-iii-vi-with-moderate-to-severe-facial-hyperpigmentation
#3
Monique J Vanaman Wilson, Isabela T Jones, Joanna Bolton, Lisa Larsen, Douglas C Wu, Mitchel P Goldman
<p>Purpose: Though hydroquinone (HQ) remains the gold standard for treatment of hyperpigmentation, concerns about its safety have prompted the development of HQ-free topical skin lightening systems. OBJECTIVE: To compare the efficacy and tolerability of a new HQ-free system and a popular HQ-based system for the improvement of facial hyperpigmentation and photoaging in darker skin types. METHODS: This investigator-blinded trial randomized 30 subjects of Fitzpatrick skin types III to VI with moderate to severe hyperpigmentation to a new 7-product HQ-free system or a 7-product HQ-based system for 12 weeks...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29139362/efficacy-and-tolerability-of-a-twice-daily-three-step-men-s-skincare-regimen-in-improving-overall-skin-quality-and-reducing-shave-related-irritation
#4
Katie Rodan, Kathy Fields, Timothy J Falla
More men are beginning to take advantage of opportunities to improve the health and appearance of their skin; however, the effectiveness of men's skincare regimens has not been well studied. The authors investigated the efficacy and tolerance of a twice-daily, three-step men's skincare regimen in improving skin appearance and reducing shave-related issues. Twenty-nine men who used a wet-shaving method completed a specific, three-step, twice-daily facial regimen-a Shave Cleanser, a Post-Shave Treatment, and Day Protection-in place of their usual routine for 4 weeks...
2017: Skinmed
https://www.readbyqxmd.com/read/29067717/haptic-augmented-skin-surface-generation-toward-telepalpation-from-a-mobile-skin-image
#5
K Kim
BACKGROUND/PURPOSE: Very little is known about the methods of integrating palpation techniques to existing mobile teleskin imaging that delivers low quality tactile information (roughness) for telepalpation. However, no study has been reported yet regarding telehaptic palpation using mobile phone images for teledermatology or teleconsultations of skincare. METHODS: This study is therefore aimed at introducing a new algorithm accurately reconstructing a haptic augmented skin surface for telehaptic palpation using a low-cost clip-on microscope simply attached to a mobile phone...
October 25, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28983938/effects-of-moisturizing-skincare-on-skin-barrier-function-and-the-prevention-of-skin-problems-in-3-month-old-infants-a-randomized-controlled-trial
#6
Kaori Yonezawa, Megumi Haruna, Masayo Matsuzaki, Mie Shiraishi, Reiji Kojima
An effective newborn skincare protocol has not been established. We aimed to evaluate the effects of moisturizing skincare, including using lotion and reducing routine bathing. Our hypothesis was that moisturizing skincare would improve skin barrier function. This randomized controlled trial included 227 healthy Asian newborns between 1 week and 3 months old. We compared moisturizing skincare (bathing every 2 days and using lotion daily; intervention, n = 113) to daily bathing without lotion (control, n = 114)...
October 6, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28963772/bacterial-cellulose-skin-masks-properties-and-sensory-tests
#7
Guilherme Pacheco, Carolina Véspoli de Mello, Bruna Galdorfini Chiari-Andréo, Vera Lucia Borges Isaac, Sidney José Lima Ribeiro, Édison Pecoraro, Eliane Trovatti
BACKGROUND: Bacterial cellulose (BC) is a versatile material produced by microorganisms in the form of a membranous hydrogel, totally biocompatible, and endowed with high mechanical strength. Its high water-holding capacity based on its highly porous nanofibrillar structure allows BC to incorporate and to release substances very fast, thus being suitable for the preparation of skincare masks. AIMS: The preparation and characterization of cosmetic masks based on BC membranes and active cosmetics...
September 29, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28961169/anti-inflammatory-thioredoxin-family-proteins-for-medicare-healthcare-and-aging-care
#8
REVIEW
Junji Yodoi, Yoshiyuki Matsuo, Hai Tian, Hiroshi Masutani, Takashi Inamoto
Human thioredoxin (TRX) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys-, which is induced by biological stress due to oxidative damage, metabolic dysfunction, chemicals, infection/inflammation, irradiation, or hypoxia/ischemia-reperfusion. Our research has demonstrated that exogenous TRX is effective in a wide variety of inflammatory diseases, including viral pneumonia, acute lung injury, gastric injury, and dermatitis, as well as in the prevention and amelioration of food allergies...
September 29, 2017: Nutrients
https://www.readbyqxmd.com/read/28947284/dermatology-in-orbit-anticipating-skincare-requirements-in-the-space-age
#9
EDITORIAL
Audrey Rutherford, Donald A Glass, Stephanie Savory
No abstract text is available yet for this article.
September 22, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28912875/inhibitory-effect-of-burdock-leaves-on-elastase-and-tyrosinase-activity
#10
Chi-Ting Horng, Hsing-Chen Wu, Ni-Na Chiang, Chiu-Fang Lee, Yu-Syuan Huang, Hui-Yun Wang, Jai-Sing Yang, Fu-An Chen
Burdock (Arctium lappa L.) leaves generate a considerable amount of waste following burdock root harvest in Taiwan. To increase the use of burdock leaves, the present study investigated the optimal methods for producing burdock leaf extract (BLE) with high antioxidant polyphenolic content, including drying methods and solvent extraction concentration. In addition, the elastase and tyrosinase inhibitory activity of BLE was examined. Burdock leaves were dried by four methods: Shadow drying, oven drying, sun drying and freeze-drying...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28884844/an-open-label-clinical-trial-assessing-the-efficacy-and-safety-of-bend-skincare-anti-aging-formula-on-minimal-erythema-dose-in-skin
#11
Nancy L Morse, Anna-Jean Reid, Marc St-Onge
BACKGROUND/PURPOSE: Sunburn and other health risks associated with excess sun exposure place huge economic burdens on societies, and create discomfort and disease within susceptible individuals. Oral supplements that reduce sunburn may be advantageous. This study evaluated the safety and efficacy of Bend Skincare Anti-Aging Formula to ameliorate sunburn induced with a solar simulator. METHODS: Subjects (n = 28) with Fitzpatrick skin phototypes I, II, or III took 4 capsules daily of the supplement providing 1400 mg of eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA), 120 mg of gamma-linolenic acid (GLA), 5 mg of lutein, 2...
September 8, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28844799/exposure-to-benzophenone-3-and-reproductive-toxicity-a-systematic-review-of-human-and-animal-studies
#12
REVIEW
Marya Ghazipura, Richard McGowan, Alan Arslan, Tanzib Hossain
Hydroxy-4-methoxybenzophenone, also known as benzophenone-3 (BP-3), is a commonly used ultraviolet filter in skincare and as a food additive. Large concentrations of similar phenolic compounds have been detected in urine, amniotic fluid, and placental tissue, thereby raising questions about its impact on reproduction. The objective of this paper was to investigate the reproductive toxicity of BP-3 in humans and animals. In humans, studies showed that high levels of BP-3 exposure could be linked to an increase in male birth weight but a decline in female birth weight and male gestational age...
August 24, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28697226/randomized-split-face-d%C3%A3-collet%C3%A3-comparative-trial-of-procedure-enhancement-system-for-fractional-non-ablative-laser-resurfacing-treatment
#13
Deanne Mraz Robinson, Ashton P Frulla
<p>INTRODUCTION: A topical proprietary procedural enhancement system (PES) containing a combination of active ingredients including a tripeptide and hexapeptide (TriHex Technology™, Alastin Procedure Enhancement Invasive System, ALASTIN Skincare™, Inc., Carlsbad, CA) has been used successfully to aid in healing and improve symptomatology following resurfacing procedures.</p> <p>METHODS: PES (Gentle Cleanser, Regenerating Skin Nectar with TriHex Technology™, Ultra Nourishing Moisturizer with TriHex Technology™, Soothe + Protect Recovery Balm, Broad Spectrum 30+ Sunscreen) was compared to a basic regimen (Aquaphor™, Cerave™ cleanser, Vanicream™, Alastin Broad Spectrum 30+ Sunscreen) in a split face/ décolleté trial following fractional non-ablative thulium-doped resurfacing treatment to the face or décolleté...
July 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28659037/myrcene-an-aromatic-volatile-compound-ameliorates-human-skin-extrinsic-aging-via-regulation-of-mmps-production
#14
Eunson Hwang, Hien T T Ngo, Bom Park, Seul-A Seo, Jung-Eun Yang, Tae-Hoo Yi
Myrcene is an aromatic volatile compound that is commercially well-known as a flavor ingredient in the food industry and a fragrance in the soap and detergent industry. Given the worldwide interest in natural antiphotoaging products, we investigated the protective effects of myrcene in UVB-irradiated human dermal fibroblasts (NHDFs). NHDFs were subjected to 144[Formula: see text]mJ/cm(2)of UVB irradiation. The expression of intracellular reactive oxygen species (ROS), matrix metalloproteinase-1 (MMP-1), MMP-3, interleukin-6 (IL-6), transforming growth factor (TGF-[Formula: see text]1) and type I procollagen were examined...
2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28652793/evaluation-of-a-novel-very-high-sun-protection-factor-moisturizer-in-adults-with-rosacea-prone-sensitive-skin
#15
Mathieu Grivet-Seyve, Francine Santoro, Nadège Lachmann
BACKGROUND/OBJECTIVE: Rosacea-prone sensitive skin requires high sun-protection factor (SPF) moisturizers. This study evaluated Daylong Extreme SPF 50+ lotion, a novel cream containing five ultraviolet filters, two emollients, and three skin conditioners. SUBJECTS AND METHODS: This was an open-label, single-center study. On day 1, before treatment, subjects answered a questionnaire on their skin conditions and sunscreen habits, and both subjects and dermatologist evaluated skin status...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28600081/a-daily-skincare-regimen-with-a-unique-ceramide-and-filaggrin-formulation-rapidly-improves-chronic-xerosis-pruritus-and-quality-of-life-in-older-adults
#16
Anne Lynn S Chang, Suephy C Chen, Lars Osterberg, Staci Brandt, Erika C von Grote, Matthew H Meckfessel
A skin care regimen which significantly improved atopic dermatitis and pruritus was evaluated for its efficacy and acceptability in senior subjects diagnosed with xerosis who also suffer from pruritus. This was an open-label, single-center study, designed to evaluate the daily use of a skin care regimen for 15 days. Assessments were made at baseline, day 8 and day 15 for visual skin dryness, transepidermal water loss (TEWL), hydration, desquamation, subject-perceived itch and quality of life (QoL). Twenty-five subjects, ages 60-73 years, had significantly improved skin visual dryness, hydration, desquamation, itch and QoL at days 8 and 15, relative to baseline (P < ...
June 6, 2017: Geriatric Nursing
https://www.readbyqxmd.com/read/28590053/bryostatin-and-its-synthetic-analog-picolog-rescue-dermal-fibroblasts-from-prolonged-stress-and-contribute-to-survival-and-rejuvenation-of-human-skin-equivalents
#17
Tapan K Khan, Paul A Wender, Daniel L Alkon
Skin health is associated with the day-to-day activity of fibroblasts. The primary function of fibroblasts is to synthesize structural proteins, such as collagen, extracellular matrix proteins, and other proteins that support the structural integrity of the skin and are associated with younger, firmer, and more elastic skin that is better able to resist and recover from injury. At sub-nanomolar concentrations (0.03-0.3 nM), bryostatin-1 and its synthetic analog, picolog (0.1-10 nM) sustained the survival and activation of human dermal fibroblasts cultured under the stressful condition of prolonged serum deprivation...
February 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28573779/a-skincare-combined-with-combination-of-adapalene-and-benzoyl-peroxide-provides-a-significant-adjunctive-efficacy-and-local-tolerance-benefit-in-adult-women-with-mild-acne
#18
A Bouloc, E Roo, B Imko-Walczuk, A Moga, B Chadoutaud, B Dréno
INTRODUCTION: Acne in adult women is an increasing reason for dermatological consultations. OBJECTIVE: The aim of this study was to assess in adult women with mild acne the efficacy and tolerance of a daily adjunctive application of a skincare (Normaderm(®) , Laboratoires Vichy, France) to a fixed combination of adapalene/benzoyl peroxide daily or every other evening and a standard emollient. METHODS: Subjects were randomized to receive the fixed combination applied either every evening or every other evening and a daily application of the standard emollient and the test care or a once daily application of the fixed combination and the standard emollient alone...
October 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28552036/in-vitro-evaluation-of-spirulina-platensis-extract-incorporated-skin-cream-with-its-wound-healing-and-antioxidant-activities
#19
Seda Gunes, Sedef Tamburaci, Meltem Conk Dalay, Ismet Deliloglu Gurhan
CONTEXT: Algae have gained importance in cosmeceutical product development due to their beneficial effects on skin health and therapeutical value with bioactive compounds. Spirulina platensis Parachas (Phormidiaceae) is renowned as a potential source of high-value chemicals and recently used in skincare products. OBJECTIVE: This study develops and evaluates skin creams incorporated with bioactive S. platensis extract. MATERIALS AND METHODS: Spirulina platensis was cultivated, the aqueous crude extract was prepared and in vitro cytotoxicity of S...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28287048/lycium-barbarum-polysaccharide-protects-human-keratinocytes-against-uvb-induced-photo-damage
#20
Huaping Li, Zhenjie Li, Liqian Peng, Na Jiang, Qing Liu, Erting Zhang, Bihua Liang, Runxiang Li, Huilan Zhu
Ultraviolet B (UVB) irradiation plays a key role in skin damage, which induces oxidative and inflammatory damages, thereby causing photoaging or photocarcinogenesis. Lycium barbarum polysaccharide (LBP), the most biologically active fraction of wolfberry, possesses significant antioxidative and anti-inflammatory effects on multiple tissues. In the present study, the photoprotective effects and potential underlying molecular mechanisms of LBP against UVB-induced photo-damage were investigated in immortalized human keratinocytes (HaCaT cells)...
February 2017: Free Radical Research
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