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https://www.readbyqxmd.com/read/29873839/a-novel-method-to-measure-skin-mechanical-properties-with-three-dimensional-digital-image-correlation
#1
Z Xu, J Dela Cruz, C Fthenakis, C Saliou
BACKGROUND: Measuring skin mechanical properties has been of great interest in the skincare industry. It is a high accuracy and non-invasive optical technique which quantitatively tracks skin movement and deformation under mechanical perturbations. METHODS: A study was conducted with female subjects (25-65 years old). A refined speckle pattern applied onto the skin surface was used for DIC measurements. A unidirectional force pulled the skin at a constant velocity, while the deformation process was quantified by the DIC...
June 6, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29773006/antimelanogenesis-and-anti-inflammatory-activity-of-selected-culinary-medicinal-mushrooms
#2
Hazwani Mat Saad, Kae Shin Sim, Yee Shin Tan
Five culinary-medicinal mushrooms are commonly available in the Malaysian market: Agaricus bisporus (white and brown), Ganoderma lucidum, Hypsizygus marmoreus, Pleurotus floridanus, and P. pulmonarius. These species were selected for use in the current study, the aim of which was to investigate the antimelanogenesis and anti-inflammatory activity of these mushrooms in an attempt to evaluate their potential use in cosmeceuticals. Mushroom fruiting bodies were extracted with hot water, and the extracts were freeze-dried before testing...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29768726/ribes-nigrum-l-prevents-uvb-mediated-photoaging-in-human-dermal-fibroblasts-potential-antioxidant-and-anti-inflammatory-activity
#3
Lu Li, Eunson Hwang, Hien T T Ngo, Seul A Seo, Pei Lin, Wei Gao, Ying Liu, Tae-Hoo Yi
Black currants (Ribes nigrum L, RN) are known as a "super fruit" to possess for their many potential health benefits such as the alleviation of oxidative stress-related disorders. However, little skin photoaging-related research has been done on the use of this agent. In the present study, we investigated the protective effects of RN in UVB-irradiated human dermal fibroblasts (NHDFs). RN treatment in UVB-irradiated skin models alleviated UVB-mediated photoaging through several mechanisms: Treatment with RN downregulated MAPK-related signaling models, such as those of activation protein 1 (AP-1) and nuclear factor kappa B (NF-κB)...
May 16, 2018: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29749695/promoting-new-concepts-of-skincare-via-skinomics-and-systems-biology-from-traditional-skincare-and-efficacy-based-skincare-to-precision-skincare
#4
REVIEW
Biao Jiang, Yan Jia, Congfen He
Traditional skincare involves the subjective classification of skin into 4 categories (oily, dry, mixed, and neutral) prior to skin treatment. Following the development of noninvasive methods in skin and skin imaging technology, scientists have developed efficacy-based skincare products based on the physiological characteristics of skin under different conditions. Currently, the emergence of skinomics and systems biology has facilitated the development of precision skincare. In this article, the evolution of skincare based on the physiological states of the skin (from traditional skincare and efficacy-based skincare to precision skincare) is described...
May 11, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29734825/skin-and-eye-irritation-assessment-of-oil-palm-elaeis-guineensis-leaf-extract-for-topical-application
#5
Nor Zuliana Yusof, Siti Salwa Abd Gani, Zafarizal Aldrin Azizul Hasan, Zainab Idris
Many types of phytochemicals have been found to be present in oil palm leaf and could potentially be used as functional ingredients for skincare product. However, as of today, there is no published report on hazard identification and safety assessment of oil palm ( Elaeis guineensis) leaf extract (OPLE), particularly on skin and eye irritation. In this study, potential hazard of OPLE on skin and eye irritation was evaluated as an initial step to the safety assessment of OPLE. In vitro cell viability study of OPLE on normal human dermal fibroblasts showed that OPLE was nontoxic to the cells with percentage viability more than 90% after 24 and 48 hours of incubation...
January 1, 2018: International Journal of Toxicology
https://www.readbyqxmd.com/read/29692619/personalized-skincare-from-molecular-basis-to-clinical-and-commercial-applications
#6
REVIEW
Ewa Markiewicz, Olusola Clement Idowu
Individual responses of human skin to the environmental stress are determined by differences in the anatomy and physiology that are closely linked to the genetic characteristics such as pigmentation. Ethnic skin phenotypes can be distinguished based on defined genotypic traits, structural organization and compartmentalized sensitivity to distinct extrinsic aging factors. These differences are not only responsible for the variation in skin performance after exposure to damaging conditions, but can also affect the mechanisms of drug absorption, sensitization and other longer term effects...
2018: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29663676/a-single-center-pilot-study-evaluating-a-novel-trihex-peptide-and-botanical-containing-eye-treatment-compared-to-baseline
#7
Alex Reivitis, Kian Karimi, Chester Griffiths, Ashley Banayan
BACKGROUND: Topical treatments containing tripeptide and hexapeptide (TriHex technology) have been proven to contribute to youthful skin by clearing the extracellular matrix and stimulating collagen and elastin production. OBJECTIVE: Evaluate the efficacy of a novel eye treatment containing TriHex peptides and other synergistic ingredients for the daily treatment of fine lines/crow's feet around the eyes, under eye hollowing, under eye bags, and dark circles. PATIENTS/METHODS: In this study, 10 subjects (9 female and 1 male) aged 30-60 of Fitzpatrick skin type I, II, or III were selected to use an eye treatment containing TriHex peptides and active botanicals (Alastin Restorative Eye Treatment with TriHex Technology™, ALASTIN Skincare, Inc...
June 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29596731/prevention-and-treatment-of-diaper-dermatitis
#8
Ulrike Blume-Peytavi, Varvara Kanti
Diaper dermatitis (DD) is one of the most common skin conditions that infants suffer from and their caregivers manage in the first months post-birth. As such, questions of effective prevention and treatment of the condition often arise. Nonmedical skincare practices that support healthy skin barrier function can prevent DD manifestation or alleviate the condition in many cases. The usage of barrier emollients and improved diaper technology contributes to keeping moisture and irritants away from an infant's delicate skin...
March 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29577991/effect-of-an-exfoliating-skincare-regimen-on-the-numbers-of-epithelial-squames-on-the-skin-of-operating-theatre-staff-studied-by-surface-microscopy
#9
A G Wernham, O L Cain, A M Thomas
BACKGROUND: The shedding of epithelial squames (skin scales) by staff in operating theatre air is an important source of deep infection following joint replacement surgery. This is a serious complication, resulting in significant morbidity for the patient and substantial cost implications for healthcare systems. Much effort has been put into providing clean air in operating theatres, yet little attention has been given to reducing the shedding of surface skin scales at source. AIM: To develop a novel method for calculating surface skin scale density using surface microscopy, and to use it to evaluate the effect of a skincare regimen on operating theatre staff...
March 23, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29542253/facile-preparation-of-magnetic-molecularly-imprinted-polymers-for-the-selective-extraction-and-determination-of-dexamethasone-in-skincare-cosmetics-using-hplc
#10
Wei Du, Bilin Zhang, Pengqi Guo, Guoning Chen, Chun Chang, Qiang Fu
Dexamethasone-imprinted polymers were fabricated by reversible addition-fragmentation chain transfer polymerization on the surface of magnetic nanoparticles under mild polymerization conditions, which exhibited a narrow polydispersity and high selectivity for dexamethasone extraction. The dexamethasone-imprinted polymers were characterized by scanning electron microscopy, transmission electron microscope, Fourier transform infrared spectroscopy, X-ray diffraction, energy dispersive spectrometry, and vibrating sample magnetometry...
March 15, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29537448/addressing-male-facial-skin-concerns-clinical-efficacy-of-a-topical-skincare-treatment-product-for-men
#11
Elizabeth T Makino, Lily I Jiang, Priscilla Tan, Tsing Cheng, Rahul C Mehta
The growing male skincare market reflects the increased interest of men in addressing facial aging concerns and maintaining a healthy youthful appearance. Because of differences in skin structure and aging as well as in lifestyle and behavior, male facial skin presents unique challenges that may result in different priorities or treatment strategies compared to female skin. A clinical study was conducted to assess clinical efficacy and tolerability of a topical skincare treatment product that was developed to address several male facial skin concerns related to skin quality, skin aging, and shaving...
March 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29526880/emu-oil-reduces-lps-induced-production-of-nitric-oxide-and-tnf-%C3%AE-but-not-phagocytosis-in-raw-264-macrophages
#12
Tadayoshi Miyashita, Kazuhiro Minami, Minoru Ito, Ryosuke Koizumi, Yoshimasa Sagane, Toshihiro Watanabe, Koichi Niwa
Emu is the second-largest extant bird native to Australia. Emu oil, obtained from the emu's fat deposits, is used as an ingredient in cosmetic skincare products. Emu oil has been reported to improve several inflammatory symptoms; however, the mechanisms of these anti-inflammatory effects are largely unknown. This study investigated the effects of emu oil on the inflammatory macrophage response in vitro. A murine macrophage cell line, RAW 264, was incubated in culture media supplemented with or without emu oil and stimulated with lipopolysaccharide (LPS)...
April 1, 2018: Journal of Oleo Science
https://www.readbyqxmd.com/read/29493714/prevention-of-hand-eczema-effect-of-an-educational-program-versus-treatment-as-usual-results-of-the-randomized-clinical-prevex-trial
#13
Maja H Fisker, Niels E Ebbehøj, Søren Grove Vejlstrup, Jane Lindschou, Christian Gluud, Per Winkel, Jens Peter Bonde, Tove Agner
Objective Occupational hand eczema has adverse health and socioeconomic impacts for the afflicted individuals and society. Prevention and treatment strategies are needed. This study aimed to assess the effectiveness of an educational intervention on sickness absence, quality of life and severity of hand eczema. Methods PREVEX (PreVention of EXema) is an individually randomized, parallel-group superiority trial investigating the pros and cons of one-time, 2-hour, group-based education in skin-protective behavior versus treatment as usual among patients with newly notified occupational hand eczema, with follow-up after one year...
March 1, 2018: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/29470423/3-5-6-7-8-3-4-heptamethoxyflavone-a-citrus-flavonoid-inhibits-collagenase-activity-and-induces-type-i-procollagen-synthesis-in-hdfn-cells
#14
Hong-Il Kim, Yong-Un Jeong, Jong-Hyeon Kim, Young-Jin Park
Citrus fruits contain various types of flavonoids with powerful anti-aging and photoprotective effects on the skin, and have thus been attracting attention as potential, efficacious skincare agents. Here, we aimed to investigate the chemical composition of Citrus unshiu and its protective effects on photoaging. We isolated and identified a bioactive compound, 3,5,6,7,8,3',4'-heptamethoxyflavone (HMF), from C. unshiu peels using ethanol extraction and hexane fractionation. HMF inhibited collagenase activity and increased type I procollagen content in UV-induced human dermal fibroblast neonatal (HDFn) cells...
February 22, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29467107/associations-between-personal-care-product-use-patterns-and-breast-cancer-risk-among-white-and-black-women-in-the-sister-study
#15
Kyla W Taylor, Melissa A Troester, Amy H Herring, Lawrence S Engel, Hazel B Nichols, Dale P Sandler, Donna D Baird
BACKGROUND: Many personal care products include chemicals that might act as endocrine disruptors and thus increase the risk of breast cancer. OBJECTIVE: We examined the association between usage patterns of beauty, hair, and skin-related personal care products and breast cancer incidence in the Sister Study, a national prospective cohort study (enrollment 2003-2009). METHODS: Non-Hispanic black (4,452) and white women (n=42,453) were examined separately using latent class analysis (LCA) to identify groups of individuals with similar patterns of self-reported product use in three categories (beauty, skin, hair)...
February 21, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29450142/arborvitae-thuja-plicata-essential-oil-significantly-inhibited-critical-inflammation-and-tissue-remodeling-related-proteins-and-genes-in-human-dermal-fibroblasts
#16
Xuesheng Han, Tory L Parker
Arborvitae ( Thuja plicata ) essential oil (AEO) is becoming increasingly popular in skincare, although its biological activity in human skin cells has not been investigated. Therefore, we sought to study AEO's effect on 17 important protein biomarkers that are closely related to inflammation and tissue remodeling by using a pre-inflamed human dermal fibroblast culture model. AEO significantly inhibited the expression of vascular cell adhesion molecule 1 (VCAM-1), intracellular cell adhesion molecule 1 (ICAM-1), interferon gamma-induced protein 10 (IP-10), interferon-inducible T-cell chemoattractant (I-TAC), monokine induced by interferon gamma (MIG), and macrophage colony-stimulating factor (M-CSF)...
June 2017: Biochimie Open
https://www.readbyqxmd.com/read/29421853/antiphotoaging-effect-of-prunus-yeonesis-blossom-extract-via-inhibition-of-mapk-ap-1-and-regulation-of-the-tgf-%C3%AE-i-smad-and-nrf2-are-signaling-pathways
#17
Lu Li, Eunson Hwang, Hien T T Ngo, Pei Lin, Wei Gao, Ying Liu, Tae-Hoo Yi
Cherry blossoms have attracted attention as an ingredient with potential for use in skincare products. However, no skin photoaging-related research has been performed with this plant. In this study, cherry blossom extract (CBE) at 1, 10 and 100 μg mL-1 was investigated for its skin antiphotoaging effects in UVB-irradiated normal human dermal fibroblasts (NHDF) cells in vitro. Our results showed that CBE markedly increased type-I procollagen during UVB exposure via two pathways. Firstly, transcription activator protein-1 expression and MAP kinases were downregulated, consequently reducing the production of matrix metalloproteinase (MMP)-1 and MMP-3...
February 8, 2018: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29384713/taking-a-proactive-approach-to-mild-to-moderate-chronic-oedema-a-case-study
#18
Diane Jehu, Linda Jenkins, Karen Morgan, Melanie J Thomas
This case study demonstrates the benefits of early intervention and a proactive approach for a patient with chronic oedema living in the community. These benefited the patient and also supported value-based healthcare in the NHS. The patient's health and wellbeing significantly improved with an assessment of his chronic oedema and a management plan consisting of skincare, an exercise and movement programme and the introduction of a class 1 British standard compression garment.
February 2, 2018: British Journal of Community Nursing
https://www.readbyqxmd.com/read/29164778/open-label-study-assessing-the-efficacy-and-tolerability-of-topical-skincare-and-sun-protection-products-following-intense-pulsed-light-treatment
#19
Isabela T Jones, Isabella Guiha, Sabrina G Fabi
BACKGROUND: The visible signs of photodamage can be improved by intense pulsed light (IPL). Active ingredients in cosmeceuticals also have effects on skin quality and pigmentation, and can camouflage post-treatment side effects. Combination therapies utilizing different treatment modalities have been shown to optimize clinical outcomes for skin rejuvenation and patient satisfaction. AIM: To evaluate the efficacy of a combination of IPL with a daily topical skincare and sunscreen regimen for the treatment of facial photodamage and for the improvement of IPL treatment tolerability...
November 21, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29142178/actual-consumption-amount-of-personal-care-products-reflecting-japanese-cosmetic-habits
#20
COMPARATIVE STUDY
Masahiko Yamaguchi, Daisuke Araki, Takeshi Kanamori, Yasuko Okiyama, Hirokazu Seto, Masaki Uda, Masahito Usami, Yutaka Yamamoto, Takuji Masunaga, Hitoshi Sasa
Safety assessments of cosmetics are carried out by identifying possible harmful effects of substances in cosmetic products and assessing the exposure to products containing these substances. The present study provided data on the amounts of cosmetic products consumed in Japan to enhance and complement the existing data from Europe and the United States, i.e., the West. The outcomes of this study increase the accuracy of exposure assessments and enable more sophisticated risk assessment as a part of the safety assessment of cosmetic products...
2017: Journal of Toxicological Sciences
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