keyword
MENU ▼
Read by QxMD icon Read
search

Optic

keyword
https://www.readbyqxmd.com/read/28743169/development-and-validation-of-an-optical-biosensor-for-rapid-monitoring-of-adalimumab-in-serum-of-patients-with-crohn-s-disease
#1
Sumin Bian, Jiadi Lu, Filip Delport, Séverine Vermeire, Dragana Spasic, Jeroen Lammertyn, Ann Gils
Therapeutic drug monitoring of adalimumab is recommended to improve therapeutic outcome in patients with Crohn's disease. Performing an ELISA requires a rather long time-to-result and the necessity of collecting multiple samples in order to decrease the cost per adalimumab determination. In this study, we aim to develop and validate a rapid assay suitable for measuring a single adalimumab serum sample using a fiber-optic surface plasmon resonance (FO-SPR) based sensor. Therefore, we have immobilized MA-ADM28B8 as capture antibody on a FO-probe and conjugated MA-ADM40D8 as detecting antibody to gold nanoparticles...
July 25, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28743087/quinoline-containing-acetyl-hydrazone-an-easily-accessible-switch-on-optical-chemosensor-for-zn-2
#2
Wei-Na Wu, Pan-Dong Mao, Yuan Wang, Xiao-Lei Zhao, Zhou-Qing Xu, Zhi-Hong Xu, Yuan Xue
A simple chemosensor, namely, N-((quinolin-8-yl)methylene)acetohydrazide (1) was synthesized and used as an off-on fluorescence sensor, which exhibits high selectivity toward Zn(2+) in aqueous media. The probe has large Stokes shift of >200nm, and its detection limit for Zn(2+) is 89.3nM. The binding process was confirmed through UV-vis absorption analysis, fluorescence measurements, mass spectroscopy study, (1)H NMR spectra and density functional theory calculation. The crystal structures of Zn(2+), Ni(2+), and Cu(2+) complexes based on 1 were determined through X-ray crystallographic analysis...
July 17, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28743030/reactive-ceo2-nanofluids-for-uv-protective-films
#3
Rafael Maniglia, Kenneth J Reed, John Texter
We investigate surface modification by organo-trimethoxysilanes of nano-ceria and if such surface-modified nano-ceria can be transformed into solvent-free nanofluids. We also examine whether simultaneous modification with ionic liquid salts and with acrylate groups yields nanofluids suitable for forming UV-protective films and clear coatings by UV-initiated polymerization. Nominally 3nm diameter CeO2 was successfully synthesized and surface decorated with an ionic liquid salt and with acrylate groups to produce a core/shell structured solvent-free nanofluid after ion exchange of chloride for a soft polyoxyethylene sulfonate anion...
July 18, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28743019/motion-vision-cortical-preferences-influenced-by-retinal-direction-selectivity
#4
Ryan D Morrie, Marla B Feller
A recent study shows that retinal direction selectivity influences a subset of cells in primary visual cortex which respond to the optic flow associated with forward motion, while other cortical direction selective cells perform this computation independently.
July 24, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28742969/fabrication-of-a-new-lineage-of-artificial-luciferases-from-natural-luciferase-pools
#5
Sung Bae Kim, Ryo Nishihara, Daniel Citterio, Koji Suzuki
The fabrication of artificial luciferases (ALucs) with unique optical properties can have a fundamental impact on bioassays and molecular imaging. In this study, we developed a new lineage of ALucs with unique substrate preferences by extracting consensus amino acids from the alignment of 25 copepod luciferase sequences available in published databases. The primary sequence was first created with a sequence logo generator resulting in a total of 11 sibling sequences. Phylogenetic analysis shows that the newly fabricated ALucs form an independent branch, genetically isolated from the natural luciferases and from a prior series of ALucs produced by our laboratory using a smaller basis set...
July 25, 2017: ACS Combinatorial Science
https://www.readbyqxmd.com/read/28742869/ultrasound-non-invasive-measurement-of-intracranial-pressure-in-neurointensive-care-a-prospective-observational-study
#6
Chiara Robba, Danilo Cardim, Tamara Tajsic, Justine Pietersen, Michael Bulman, Joseph Donnelly, Andrea Lavinio, Arun Gupta, David K Menon, Peter J A Hutchinson, Marek Czosnyka
BACKGROUND: The invasive nature of the current methods for monitoring of intracranial pressure (ICP) has prevented their use in many clinical situations. Several attempts have been made to develop methods to monitor ICP non-invasively. The aim of this study is to assess the relationship between ultrasound-based non-invasive ICP (nICP) and invasive ICP measurement in neurocritical care patients. METHODS AND FINDINGS: This was a prospective, single-cohort observational study of patients admitted to a tertiary neurocritical care unit...
July 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28742840/glaucomatous-changes-in-lamina-pores-shape-within-the-lamina-cribrosa-using-wide-bandwidth-femtosecond-mode-locked-laser-oct
#7
Takuhei Shoji, Hiroto Kuroda, Masayuki Suzuki, Hisashi Ibuki, Makoto Araie, Shin Yoneya
PURPOSE: The lamina cribrosa (LC) is known to play a critical role in the pathogenesis of glaucoma. Although it has been reported that striae-shaped or slit-shaped lamina pores are more frequent in eyes with primary open angle glaucoma (POAG), this observation is based only on fundus photography. The primary object of this study is to perform layer-by-layer comparisons of the shape of lamina pores within the LC in vivo. DESIGN: Cross-sectional study. METHODS: Optic nerve head B-scans were obtained using custom-made broad-wavelength optical coherence tomography with a mode-locked laser...
2017: PloS One
https://www.readbyqxmd.com/read/28742641/does-nocturnal-hypotension-play-a-causal-role-in-nonarteritic-anterior-ischemic-optic-neuropathy-response
#8
Anthony C Arnold
No abstract text is available yet for this article.
July 24, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28742640/role-of-nocturnal-arterial-hypotension-in-nonarteritic-anterior-ischemic-optic-neuropathy
#9
Sohan Singh Hayreh
No abstract text is available yet for this article.
July 24, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28742359/pressure-induced-structural-and-optical-properties-of-inorganic-halide-perovskite-cspbbr3
#10
Long Zhang, Qingxin Zeng, Kai Wang
Perovskite photovoltaic materials are gaining sustained attention because of their excellent photovoltaic properties and extensive practical applicability. In this letter, we discussed the changes in the structure and optical properties of CsPbBr3 under high pressure. As the pressure increases, the band gap initially begun to redshift before 1.0 GPa followed by continuous blue shift until the crystal was completely amorphized. An isostructural phase transition at 1.2 GPa was determined by high-pressure synchrotron X-ray and Raman spectroscopy...
July 25, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28742348/an-observation-of-structural-wavepacket-motion-the-umbrella-mode-in-rydberg-excited-n-methyl-morpholine
#11
Yao Zhang, Sanghamitra Deb, Hannes Jonsson, Peter M M Weber
We have observed time-resolved, structural dynamics of a coherent vibrational wavepacket in Rydberg-excited N-methyl morpholine, a molecule with 48 internal degrees of freedom. The molecular structure was established by associating the time-dependent Rydberg electron binding energy, obtained from time-resolved photoionization-photoelectron spectroscopy, to the molecular structure using self-interaction corrected density functional calculations. Optical excitation at 226 nm launches an oscillatory wavepacket in the amine umbrella coordinate with a 650 fs period...
July 25, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28742331/deep-ultraviolet-nonlinear-optical-material-k3sr3li2al4b6o20f-addressing-the-structural-instability-problem-in-kbe2bo3f2
#12
Hongping Wu, Hongwei Yu, Shilie Pan, P Shiv Halasyamani
A beryllium-free deep-ultraviolet (DUV) nonlinear-optical (NLO) material, K3Sr3Al4Li2B6O20F, has been synthesized and characterized. Unlike KBe2BO3F2 (KBBF), the reported NLO material does not require the use of toxic BeO in the synthesis, and through the judicious selection of cations, strong interlayer interactions are observed that facilitate the crystal growth. K3Sr3Al4Li2B6O20F exhibits second-harmonic generation (SHG) at both 1064 and 532 nm with efficiencies of 1.7KH2PO4 and 0.3β-BaB2O4 and has an absorption edge of 190 nm...
July 25, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28742256/effect-of-chenopodium-ambrosioides-on-the-healing-process-of-the-in-vivo-bone-tissue
#13
Elizandra Silva da Penha, Rogério Lacerda-Santos, Maria Goretti Freire de Carvalho, Patrícia Teixeira de Oliveira
The focus of this double-blind randomized study was on evaluating the effect of an aqueous extract of Mastruz (Chenopodium ambrosioides L.) on the bone repair process in vivo. In total, 36 male Wistar rats were randomly selected for this study, and divided into 3 groups (n = 12): Group HS (Hemostatic Sponge), Group SM (Hemostatic Sponge with Mastruz) and Group BC (Blood Clot). In each animal, bone defects measuring 2 mm in diameter were performed in both tibias for placement of the substances. After 3 and 10 days, the animals were sacrificed, and the tissues were analyzed under an optical microscope relative to the following events: inflammatory infiltrate; necrosis; young fibroblasts; osteoclastic and osteoblastic activity; endosteal and periosteal bone formation; and bone repair...
July 25, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28742160/sub-classification-of-myopic-glaucomatous-eyes-according-to-optic-disc-and-peripapillary-features
#14
Seungbong Han, Kyung Rim Sung, Jimin Park, Joo Young Yoon, Joong Won Shin
PURPOSE: To investigate the sub-classification of myopic glaucomatous eyes by optic disc and peripapillary features. METHODS: Optic disc tilt and torsion were determined from retinal nerve fiber layer photographs. Based on the location of the Bruch's membrane (BM) opening within the β-zone of the peripapillary atrophy (PPA) area, the widths of β-zone PPA (PPA1W), PPA+BM (PPA2W), and PPA-BM (PPA3W) were measured with enhanced depth imaging spectral-domain optical coherence tomography...
2017: PloS One
https://www.readbyqxmd.com/read/28742142/effects-of-water-drinking-test-on-ocular-blood-flow-waveform-parameters-a-laser-speckle-flowgraphy-study
#15
Mehwish Saba Bhatti, Tong Boon Tang, Augustinus Laude
The water-drinking test (WDT) is a provocative test used in glaucoma research to assess the effects of elevated intraocular pressure (IOP). Defective autoregulation due to changes in perfusion pressure may play a role in the pathophysiology of several ocular diseases. This study aims to examine the effects of WDT on ocular blood flow (in the form of pulse waveform parameters obtained using laser speckle flowgraphy) to gain insight into the physiology of ocular blood flow and its autoregulation in healthy individuals...
2017: PloS One
https://www.readbyqxmd.com/read/28742058/ito-with-embedded-silver-grids-as-transparent-conductive-electrodes-for-large-area-organic-solar-cells
#16
Bhushan Ramesh Patil, Mina Mirsafaei, Pawel Piotr Cielecki, Andre Luis Fernandes Cauduro, Jacek Fiutowski, Horst-Guenter Rubahn, Morten Madsen
In this work, development of semi-transparent electrodes for efficient large area organic solar cells (OSCs) has been demonstrated. Electron beam evaporated silver grids were embedded in commercially available ITO coatings on glass, through a standard negative photolithography process, in order to improve the conductivity of planar ITO substrates. The fabricated electrodes with embedded line and square patterned Ag grids reduced the sheet resistance of ITO by 25 % and 40 %, respectively, showing optical transmittance drops of less than 6 % within the complete visible light spectrum for both patterns...
July 25, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28742054/laue-lens-for-radiotherapy-applications-through-a-focused-hard-x-ray-beam-a-feasibility-study-on-requirements-and-tolerances
#17
Riccardo Camattari
Focusing a hard X-ray beam would represent an innovative technique for tumour treatment, since such a beam may deliver a dose to a tumour located at a given depth under the skin, sparing the surrounding healthy cells. A detailed study of a focusing system for hard X-ray aimed at radiotherapy is here presented. Such a focusing system, named Laue lens, exploits X-ray diffraction and consists of a series of crystals disposed as concentric rings capable of concentrating a flux of X-rays toward a focusing point...
July 25, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28741935/super-photostable-phosphole-based-dye-for-multiple-acquisition-stimulated-emission-depletion-imaging
#18
Chenguang Wang, Masayasu Taki, Yoshikatsu Sato, Aiko Fukazawa, Tetsuya Higashiyama, Shigehiro Yamaguchi
As stimulated emission depletion (STED) microscopy can provide structural details of cells with an optical resolution beyond the diffraction limit, it has become an indispensable tool in cell biology. However, the intense STED laser beam usually causes rapid photobleaching of the employed fluorescent dyes, which significantly limits the utility of STED microscopy from a practical perspective. Herein we report a new design of super-photostable dye, PhoxBright 430 (PB430), comprising a fully ring-fused π-conjugated skeleton with an electron-accepting phosphole P-oxide unit...
July 25, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28741927/rapid-antibiotic-susceptibility-testing-of-uropathogenic-e-coli-by-tracking-sub-micron-scale-motion-of-single-bacterial-cells
#19
Karan Syal, Simon Shen, Yunze Yang, Shaopeng Wang, Shelley E Haydel, Nongjian Tao
To combat antibiotic resistance, a rapid antibiotic susceptibility testing (AST) technology that can identify resistant infections at disease onset is required. Current clinical AST technologies take 1-3 days, which is often too slow for accurate treatment. Here we demonstrate a rapid AST method by tracking sub-µm scale bacterial motion with an optical imaging and tracking technique. We apply the method to clinically relevant bacterial pathogens, Escherichia coli O157: H7 and uropathogenic E. coli (UPEC) loosely tethered to a glass surface...
July 25, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28741866/a-review-of-available-laser-and-intense-light-source-home-devices-a-dermatologist-s-perspective
#20
REVIEW
Margit Lw Juhász, Melissa K Levin, Ellen S Marmur
BACKGROUND: Home optical devices are becoming an increasingly popular treatment modality sought out by patients for dermatologic pathologies such as acne, hair removal and anti-aging, as these devices are a low-cost and convenient therapy choice. METHODS: An Internet search using PubMed.gov was completed with search terms, "home device dermatology," "home device acne," "home device hair" or "hair removal," and "home device aging." RESULTS: Currently, there are multiple home optical devices available on the market...
July 25, 2017: Journal of Cosmetic Dermatology
keyword
keyword
4240
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"