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surgical site infection prevention

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https://www.readbyqxmd.com/read/28637037/surgical-site-infection-after-hepatectomy-for-hepatocellular-carcinoma
#1
Chikara Shirata, Kiyoshi Hasegawa, Takashi Kokudo, Junichi Arita, Nobuhisa Akamatsu, Junichi Kaneko, Yoshihiro Sakamoto, Masatoshi Makuuchi, Norihiro Kokudo
AIMS: To clarify the clinical impact, risk factors, and preventive methods for surgical site infection (SSI) after hepatectomy for hepatocellular carcinoma (HCC). METHODS: We included 879 consecutive patients who underwent hepatectomy for HCC between 2002 and 2011. Univariate and multivariate analyses were conducted to identify the risk factors for incisional and organ/space SSIs. ORs and 95% CIs are reported. RESULTS: The incidences of incisional and organ/space SSIs were 24 (2...
June 21, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28631985/effect-of-a-standardized-protocol-of-antibiotic-therapy-on-surgical-site-infection-after-laparoscopic-surgery-for-complicated-appendicitis
#2
Hyoung-Chul Park, Min Jeong Kim, Bong Hwa Lee
BACKGROUND: Although it is accepted that complicated appendicitis requires antibiotic therapy to prevent post-operative surgical infections, consensus protocols on the duration and regimens of treatment are not well established. This study aimed to compare the outcome of post-operative infectious complications in patients receiving old non-standardized and new standard antibiotic protocols, involving either 5 or 10 days of treatment, respectively. METHODS: We enrolled 1,343 patients who underwent laparoscopic surgery for complicated appendicitis between January 2009 and December 2014...
June 20, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28620749/bundles-prevent-surgical-site-infections-after-colorectal-surgery-meta-analysis-and-systematic-review
#3
Aleksander Zywot, Christine S M Lau, H Stephen Fletcher, Subroto Paul
INTRODUCTION: Colorectal surgeries (CRS) have one of the highest rates of surgical site infections (SSIs) with rates 15 to >30%. Prevention "bundles" or sets of evidence-based interventions are structured ways to improve patient outcomes. The aim sof this study is to evaluate CRS SSI prevention bundles, bundle components, and implementation and compliance strategies. METHODS: A meta-analysis of studies with pre- and post-implementation data was conducted to assess the impact of bundles on SSI rates (superficial, deep, and organ/space)...
June 15, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28614192/perioperative-antibiotic-prophylaxis-to-prevent-surgical-site-infections-in-solid-organ-transplantation
#4
Judith A Anesi, Emily A Blumberg, Lilian M Abbo
Antibiotic prophylaxis in the perioperative period is the standard of care for nearly all surgical procedures and routinely prescribed during solid organ transplantation (SOT). The primary goal of perioperative antibiotic prophylaxis is to minimize postoperative surgical site infections (SSIs). SSIs are a significant issue in SOT. Depending on the organ transplanted, SSIs occur in 3 to 53% of patients, with the highest rates observed in small bowel/multivisceral, liver, and pancreas transplant recipients. SOT recipients are also at increased risk of developing SSIs with antimicrobial-resistant organisms...
June 13, 2017: Transplantation
https://www.readbyqxmd.com/read/28613991/microbial-characteristics-of-nosocomial-infections-and-their-association-with-the-utilization-of-hand-hygiene-products-a-hospital-wide-analysis-of-78-344-cases
#5
Song Liu, Meng Wang, Gefei Wang, Xiuwen Wu, Wenxian Guan, Jianan Ren
BACKGROUND: Nosocomial infections are the main adverse events during health care delivery. Hand hygiene is the fundamental strategy for the prevention of nosocomial infections. Microbial characteristics of nosocomial infections in the Asia-Pacific region have not been investigated fully. Correlation between the use of hand hygiene products and the incidence of nosocomial infections is still unknown. This study investigates the microbial characteristics of nosocomial infections in the Asia-Pacific region and analyzes the association between the utilization of hand hygiene products and the incidence of nosocomial infections...
June 14, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28612116/prevention-of-parastomal-hernia-in-the-emergency-setting
#6
Anna Lykke, Johnny F B Andersen, Lars N Jorgensen, Tommie Mynster
AIM: This study assessed safety and efficacy associated with hernia prophylaxis using a retromuscular slowly resorbable synthetic mesh for stoma reinforcement. METHOD: This was a cohort study with a historic reference group. The study took place in a high-volume surgical department. During a 2-year period (July 2012-July 2014), we included 109 patients undergoing emergency surgery with formation of ileostomy or colostomy. All patients received a retromuscular slowly resorbable synthetic mesh (TIGR®, Novus Scientific) at the stoma site...
June 14, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28608250/the-efficacy-of-active-drainage-for-preventing-postoperative-organ-space-surgical-site-infections-in-patients-with-crohn-s-disease
#7
Ryo Ikeshima, Tsunekazu Mizushima, Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Taishi Hata, Chu Matsuda, Masakazu Ikenaga, Kiyokazu Nakajima, Hirofumi Yamamoto, Kohei Murata, Yuichiro Doki, Masaki Mori
PURPOSE: Patients with Crohn's disease (CD) show a higher incidence of surgical site infections (SSIs) after bowel resection in comparison to other patient populations because CD patients commonly suffer from anemia, malnutrition, and immunosuppression. In comparison to conventional passive drainage, active drainage using a closed-suction drain reportedly reduces postoperative wound-related complications in several diseases. In the present study, we aimed to investigate the incidence of SSI and to identify the risk factors for SSI in patients with CD...
June 12, 2017: Surgery Today
https://www.readbyqxmd.com/read/28608019/the-benefits-of-a-wound-protector-in-preventing-incisional-surgical-site-infection-in-elective-open-digestive-surgery-a-large-scale-cohort-study
#8
Keita Itatsu, Yukihiro Yokoyama, Gen Sugawara, Satoaki Kamiya, Masaki Terasaki, Atsushi Morioka, Shinsuke Iyomasa, Kazuhisa Shirai, Masahiko Ando, Masato Nagino
BACKGROUND: The objective of this study was to evaluate the benefits of wound protectors (WPs) in preventing incisional surgical site infection (I-SSI) in open elective digestive surgery using data from a large-scale, multi-institutional cohort study. METHODS: Patients who had elective digestive surgery for malignant neoplasms between November 2009 and February 2011 were included. The protective value of WPs against I-SSI was evaluated. RESULTS: A total of 3201 patients were analyzed...
June 12, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28607871/prevention-of-surgical-site-infections-and-biofilms-pharmacokinetics-of-subcutaneous-cefazolin-and-metronidazole-in-a-tumescent-lidocaine-solution
#9
Jeffrey A Klein, Loralie J Langman
BACKGROUND: Tumescent anesthesia antibiotic delivery (TAAD) consists of subcutaneous infiltration of antibiotic(s) dissolved tumescent lidocaine anesthesia. Tumescent lidocaine anesthesia contains lidocaine (≤ 1 g/L), epinephrine (≤ 1 mg/L), sodium bicarbonate (10 mEq/L) in 0.9% saline. Our aim was to measure cefazolin and metronidazole concentrations over time in subcutaneous tumescent interstitial fluid (TISF) after TAAD, in serum after TAAD and after intravenous antibiotic delivery (IVAD)...
May 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28607014/np108-an-antimicrobial-polymer-with-activity-against-methicillin-and-mupirocin-resistant-staphylococcus-aureus
#10
Derry K Mercer, Laura K Katvars, Fiona Hewitt, Daniel W Smith, Jennifer Robertson, Deborah A O'Neil
Staphylococcus aureus is a clinically significant human pathogen that causes infectious diseases ranging from skin and soft tissue infections (SSTI), healthcare associated infections (HAI) to potentially fatal bacteraemia and endocarditis. Nasal carriage of S. aureus, especially persistent carriage, is associated with an increased risk of subsequent infection, particularly nosocomial and surgical site infections (SSI), usually via autoinfection. NP108 is a cationic antimicrobial polymer composed of Generally Recognized as Safe (GRAS) amino acid building blocks...
June 12, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28602643/the-use-of-negative-pressure-wound-therapy-to-prevent-post-operative-surgical-site-infections-following-pancreaticoduodenectomy
#11
Richard A Burkhart, Ammar A Javed, Sean Ronnekleiv-Kelly, Michael J Wright, Katherine E Poruk, Frederic Eckhauser, Martin A Makary, John L Cameron, Christopher L Wolfgang, Jin He, Matthew J Weiss
BACKGROUND: Rates of superficial surgical site infection (SSI) following pancreaticoduodenectomy remain high. Following resection for cancer, complications such as SSI impact adjuvant therapy delivery and portend worse survival. An incisional negative pressure dressing (iVAC) has been demonstrated to reduce SSI in other high-risk cohorts. METHODS: Following a comprehensive effort to identify patients at high risk for SSI, the practice patterns at a single academic center shifted and iVAC use increased...
June 8, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28602223/is-enhanced-recovery-enough-for-reducing-30-d-readmissions-after-surgery
#12
Anne C Fabrizio, Michael C Grant, Zishan Siddiqui, Yewande Alimi, Susan L Gearhart, Christopher Wu, Jonathan E Efron, Elizabeth C Wick
BACKGROUND: Few enhanced recovery pathways (ERPs) include processes related to the hospital to home transfer. Little has been reported regarding readmissions in enhanced recovery programs. This study evaluates readmissions and identifies areas to optimize ERPs to prevent readmissions. METHODS: We conducted an observational, retrospective study at a single tertiary care center. Patients in an ERP for colorectal surgery were compared with a similar cohort who underwent surgery before protocol implementation...
April 22, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28601329/predictors-of-readmission-in-nonagenarians-analysis-of-the-american-college-of-surgeons-national-surgical-quality-improvement-project-dataset
#13
Zachary Hothem, Dustin Baker, Christina S Jenkins, Jason Douglas, Rose E Callahan, Catherine C Shuell, Graham W Long, Robert J Welsh
BACKGROUND: Increased longevity has led to more nonagenarians undergoing elective surgery. Development of predictive models for hospital readmission may identify patients who benefit from preoperative optimization and postoperative transition of care intervention. Our goal was to identify significant predictors of 30-d readmission in nonagenarians undergoing elective surgery. METHODS: Nonagenarians undergoing elective surgery from January 2011 to December 2012 were identified using the American College of Surgeons National Surgical Quality Improvement Project participant use data files...
June 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28599578/antimicrobial-and-bone-forming-activity-of-a-copper-coated-implant-in-a-rabbit-model
#14
Cornelia Prinz, Mohamed Elhensheri, Joachim Rychly, Hans-Georg Neumann
Current strategies in implant technology are directed to generate bioactive implants that are capable to activate the regenerative potential of the surrounding tissue. On the other hand, implant-related infections are a common problem in orthopaedic trauma patients. To meet both challenges, i.e. to generate a bone implant with regenerative and antimicrobial characteristics, we tested the use of copper coated nails for surgical fixation in a rabbit model. Copper acetate was galvanically deposited with a copper load of 1 µg/mm(2) onto a porous oxide layer of Ti6Al4V nails, which were used for the fixation of a tibia fracture, inoculated with bacteria...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28597284/comparison-of-single-incision-laparoscopic-percutaneous-extraperitoneal-closure-silpec-and-open-repair-for-pediatric-inguinal-hernia-a-single-center-retrospective-cohort-study-of-2028-cases
#15
Hizuru Amano, Yujiro Tanaka, Hiroshi Kawashima, Kyoichi Deie, Michimasa Fujiogi, Keisuke Suzuki, Kaori Morita, Tadashi Iwanaka, Hiroo Uchida
BACKGROUD: Recently, laparoscopic percutaneous extraperitoneal closure (LPEC) has gained increased popularity for pediatric inguinal hernia repair. To improve cosmesis, we developed single incision LPEC (SILPEC). The aim of this study was to assess the safety and feasibility of SILPEC compared with traditional open repair (OR). METHODS: This was a single-center retrospective cohort study of 2028 children who underwent inguinal hernia repair between April 2005 and August 2014...
June 8, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28594825/intraoperative-hypothermia-and-its-clinical-outcomes-in-patients-undergoing-general-anesthesia-national-study-in-china
#16
Jie Yi, Yongjing Lei, Shiyuan Xu, Yongyu Si, Shiyang Li, Zhongyuan Xia, Yisa Shi, Xiaoping Gu, Jianshe Yu, Guohai Xu, Erwei Gu, Yonghao Yu, Yanqing Chen, Hequn Jia, Yinglin Wang, Xiuli Wang, Xiaoqing Chai, Xiaoju Jin, Junping Chen, Meiying Xu, Junyu Xiong, Guonian Wang, Kaizhi Lu, Wenli Yu, Weifu Lei, Zaisheng Qin, Jingguo Xiang, Longyun Li, Ziyong Xiang, Shuang Pan, Lujing Zhan, Kai Qiu, Min Yao, Yuguang Huang
BACKGROUND/OBJECTIVE: Inadvertent intraoperative hypothermia (core temperature <36°C) is a frequently preventable complication with several adverse consequences. Our study aimed to determine the overall incidence of inadvertent intraoperative hypothermia and its risk factors associated with clinical outcomes in this national survey in China. METHODS: We conducted a national cross-sectional study with 30 days postoperative follow-up from November 2014 through August 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28584431/hospital-acquired-infection-prevalence-and-outcome-in-infants-undergoing-open-heart-surgery-in-the-present-era
#17
Manoj Kumar Sahu, Ch Bharat Siddharth, Velayudham Devagouru, Sachin Talwar, Sarvesh Pal Singh, Shiv Chaudhary, Balram Airan
BACKGROUND: The aim of this study is to evaluate the causal relation between hospital-acquired infection (HAI) and clinical outcomes following cardiac surgery in neonates and infants and to identify the risk factors for the development of HAI in this subset of patients. MATERIALS AND METHODS: After Ethics committee approval, one hundred consecutive infants undergoing open heart surgery (OHS) between June 2015 and June 2016 were included in this prospective observational study...
May 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28583892/preoperative-chlorhexidine-versus-povidone-iodine-antisepsis-for-preventing-surgical-site-infection-a-meta-analysis-and-trial-sequential-analysis-of-randomized-controlled-trials
#18
REVIEW
Dan Zhang, Xi-Chen Wang, Zeng-Xi Yang, Jian-Xin Gan, Jie-Bin Pan, Lan-Ning Yin
BACKGROUNDS: Updated guidelines for surgical site infections (SSIs) suggested that chlorhexidine (CH) or povidone-iodine (PVI) product was equally appropriate to be applied in preoperative disinfection, but which one was optimal remained ambiguous. Moreover, recent studies reported inconsistent results. Thus, an updated meta-analysis was conducted to clarify the superiority of CH or PVI for prevention of SSIs in clean and clean-contaminated surgery. METHODS: From the inception to November 2016, Pubmed, Embase, and the Cochrane library were systematically searched for randomized controlled trials (RCTs) which explored preoperative antisepsis schemes (CH or PVI) for prevention of SSIs in clean and clean-contaminated surgery...
June 2, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28573554/-prevention-of-postoperative-infections-risk-factors-and-the-current-who-guidelines-in-musculoskeletal-surgery
#19
REVIEW
Christian Willy, Hayo Rieger, Marcus Stichling
BACKGROUND: Despite the many scientific and technological advances postoperative infection continues to be a large problem for trauma and orthopedic surgeons. Based on a review of the current literature, this study provides a comprehensive overview of the risk factors (RF) and possible preventive measures to control surgical site infections. METHODS: Medline search and analysis from 1968-2017 (as of 01 March 2017). Selection of trauma and orthopedic relevant RFs and comparison with WHO recommendations (global guidelines for the prevention of surgical site infection, Nov...
June 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28571692/understanding-long-term-silver-release-from-surface-modified-porous-titanium-implants
#20
Anish Shivaram, Susmita Bose, Amit Bandyopadhyay
Prevention of orthopedic device related infection (ODRI) using antibiotics has met with limited amount of success and is still a big concern during post-surgery. As an alternative, use of silver as an antibiotic treatment to prevent surgical infections is being used due to the well-established antimicrobial properties of silver. However, in most cases silver is used in particulate form with wound dressings or with short-term devices such as catheters but not with load-bearing implants. We hypothesize that strongly adherent silver to load-bearing implants can offer longer term solution to infection in vivo...
May 29, 2017: Acta Biomaterialia
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