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surgical site infection prevention

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https://www.readbyqxmd.com/read/29674370/effect-of-a-single-prophylactic-preoperative-oral-antibiotic-dose-on-surgical-site-infection-following-complex-dermatological-procedures-on-the-nose-and-ear-a-prospective-randomised-controlled-double-blinded-trial
#1
Helena Rosengren, Clare F Heal, Petra G Buttner
OBJECTIVES: There is limited published research studying the effect of antibiotic prophylaxis on surgical site infection (SSI) in dermatological surgery, and there is no consensus for its use in higher-risk cases. The objective of this study was to determine the effectiveness of a single oral preoperative 2 g dose of cephalexin in preventing SSI following flap and graft dermatological closures on the nose and ear. DESIGN: Prospective double-blinded, randomised, placebo-controlled trial testing for difference in infection rates...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29672240/national-survey-of-operating-room-nurses-aseptic-techniques-and-interventions-for-patient-preparation-to-reduce-surgical-site-infections
#2
Camilla Wistrand, Karin Falk-Brynhildsen, Ulrica Nilsson
BACKGROUND: Surgical site infection (SSI), the third most common type of nosocomial infection in Sweden, is a patient injury that should be prevented. Methods of reducing SSIs include, for instance, disinfecting the skin, maintaining body temperature, and ensuring an aseptic environment. Guidelines for most of these interventions exist, but there is a lack of studies describing to what extent the preventive interventions have been implemented in clinical practice. We describe the daily clinical interventions Swedish operating room (OR) nurses performed to prevent SSIs following national guidelines...
April 19, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29663943/retrospective-review-of-surgical-outcomes-and-pair-housing-success-in-vasectomized-rhesus-macaques-macaca-mulatta
#3
Dilrukshi K Ekanayake-Alper, Steven R Wilson, Jodi A Scholz
Providing social housing for adult male macaques can be challenging. One successful strategy for long-term social housing of adult male macaques is to pair them with adult females; however, unwanted breeding must be prevented by sterilization of the male or female. Vasectomy is a simple, highly effective, and minimally invasive method of contraception that is used at our institution to facilitate social housing. We performed a retrospective review to analyze the surgical outcomes and rate of postoperative complications after vasectomy of adult rhesus macaques at our research facility...
April 2, 2018: Comparative Medicine
https://www.readbyqxmd.com/read/29662886/high-prevalence-of-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-among-clinical-isolates-from-cats-and-dogs-admitted-to-a-veterinary-hospital-in-switzerland
#4
Anna Lena Zogg, Sabrina Simmen, Katrin Zurfluh, Roger Stephan, Sarah N Schmitt, Magdalena Nüesch-Inderbinen
Objectives: This study aimed to identify and characterize extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae among clinical samples of companion animals. Methods: A total of 346 non-duplicate Enterobacteriaceae isolates were collected between 2012 and 2016 from diseased cats ( n  = 115) and dogs ( n  = 231). The presence of bla ESBL , PMQR genes, and the azithromycin resistance gene mph(A) was confirmed by PCR and sequencing of bla genes...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29655650/surgical-treatment-of-lisfranc-injury-with-plantar-plate-approach
#5
Deepal Dalal, Christian Curry, Ryan Carter, Colin Zdenek, Nicholas W Todd, Shannon M Rush, Richard Jensen
Midfoot injuries are the second most common athletic foot injury documented in the published data. High-energy Lisfranc dislocations are commonly seen secondary to traumatic etiologies and disrupt the strong midfoot ligaments supporting the arch. These injuries require immediate surgical intervention to prevent serious complications such as compartment syndrome and amputation. The present case series reports a new Lapidus plate system used in 3 patients who underwent arthrodesis procedures for Lisfranc joint dislocation...
April 11, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29649026/evidence-review-conducted-for-the-agency-for-healthcare-research-and-quality-safety-program-for-improving-surgical-care-and-recovery-focus-on-anesthesiology-for-colorectal-surgery
#6
Kristen A Ban, Melinda M Gibbons, Clifford Y Ko, Elizabeth C Wick, Maxime Cannesson, Michael J Scott, Michael C Grant, Christopher L Wu
The Agency for Healthcare Research and Quality, in partnership with the American College of Surgeons and the Johns Hopkins Medicine Armstrong Institute for Patient Safety and Quality, has developed the Safety Program for Improving Surgical Care and Recovery (ISCR), which is a national effort to disseminate best practices in perioperative care to more than 750 hospitals across multiple procedures in the next 5 years. The program will integrate evidence-based processes central to enhanced recovery and prevention of surgical site infection, venous thromboembolic events, catheter-associated urinary tract infections with socioadaptive interventions to improve surgical outcomes, patient experience, and perioperative safety culture...
April 11, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29628696/do-local-antibiotics-reduce-periprosthetic-joint-infections-a-retrospective-review-of-744-cases
#7
Craig Winkler, Joel Dennison, Adam Wooldridge, Eneko Larumbe, Cyrus Caroom, Mark Jenkins, George Brindley
Periprosthetic joint infections (PJI) are uncommon but not rare and have significant morbidity and financial implications. Local antibiotics have been used successfully in other areas of orthopedics to reduce postoperative infections, but this method has not been proven in total joint arthroplasty (TJA). Beginning January 1, 2014, our primary investigators began using surgical site lavage with providone-iodine solution and administering 2 g of vancomcyin powder in the surgical wound prior to capsule closure for all primary and revision total hip and knee arthroplasties...
March 2018: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29624019/therapeutic-activity-of-chlorhexidine-poloxamer-antiseptic-gel-on-wound-healing-in-rats-a-preclinical-study
#8
L Babickaite, A Grigonis, K Ramanauskiene, A P Matusevicius, G Zamokas, G Daunoras, M Ivaskiene
Despite the progress in curative and preventive medicine, skin lesions after injuries or surgical interventions are still a big problem. The aim of wound care is to get damaged tissues to heal as soon as possible. A gel-forming material helps to maintain proper humidity in the wound and promotes the healing process. For this purpose, a healing gel containing the active substance chlorhexidine based on poloxamer was prepared. The aim of this study was to assess in vivo the therapeutic efficacy of chlorhexidine-poloxamer gel in treatment of wounds caused experimentally and inoculated with bacteria, and the effect of an antiseptic gel applied on a healthy rat skin...
March 2018: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/29618877/infection-alveolar-osteitis-and-adverse-effects-using-metronidazole-in-healthy-patients-undergoing-third-molar-surgery-a-meta-analysis
#9
REVIEW
Mario Alberto Isiordia-Espinoza, Othoniel H Aragon-Martinez, Ronell E Bollogna-Molina, Ángel J Alonso-Castro
Purpose: The aim of this systematic review and meta-analysis was to evaluate the risk of surgical infection, alveolar osteitis, and adverse effects using systemic metronidazole in comparison with placebo in healthy patients undergoing third molar surgery. Materials and Methods: The eligible reports were identified from diverse science sources. Clinical trials meeting the inclusion and exclusion criteria and an acceptable Oxford Quality Score were included in this study...
June 2018: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29609860/prophylaxis-of-surgical-site-infection-in-adult-spine-surgery-a-systematic-review
#10
REVIEW
Reina Yao, Terence Tan, Jin Wee Tee, John Street
INTRODUCTION: Surgical site infection (SSI) remains a significant source of morbidity in spine surgery, with reported rates varying from 0.7 to 16%. OBJECTIVE: To systematically review and evaluate the evidence for strategies for prophylaxis of SSI in adult spine surgery in the last twenty years. METHODS: Two independent systematic searches were conducted, at two international spine centers, encompassing PubMed, ClinicalTrials.gov, Cochrane Database, EBSCO Medline, ScienceDirect, Ovid Medline, EMBASE (Ovid), and MEDLINE...
March 30, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29600816/comparison-of-chlorhexidine-isopropanol-with-isopropanol-skin-antisepsis-for-prevention-of-surgical-site-infection-after-abdominal-surgery
#11
J C Harnoss, O Assadian, A Kramer, P Probst, C Müller-Lantzsch, L Scheerer, T Bruckner, M K Diener, M W Büchler, A B Ulrich
BACKGROUND: Prevention of surgical-site infection (SSI) has received increasing attention. Clinical trials have focused on the role of skin antisepsis in preventing SSI. The benefit of combining antiseptic chlorhexidine with alcohol has not been compared with alcohol-based skin preparation alone in a prospective controlled clinical trial. METHODS: Between August and October 2014, patients undergoing abdominal surgery received preoperative skin antisepsis with 70 per cent isopropanol (PA)...
March 30, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29596598/a-survey-of-practice-and-opinions-on-the-use-of-topical-antibiotics-to-prevent-surgical-site-infection-more-confusion-than-consensus
#12
Charlotte Cooper, Carolyne Horner, Gavin Barlow, Jan Stryja, Kylie Sandy-Hodgetts, Tracey Guise, Hilary Humphreys
Background: Surgical site infection (SSI) is one of the most common causes of healthcare-associated infection. Although the use of topical antibiotics to prevent SSI is not recommended by current guidelines, published studies document conflicting results and conclusions. Objectives: The objectives of this survey were to: (i) determine the extent of the use of topical antibiotics to prevent SSI in clinical practice; and (ii) gather the opinions of healthcare professionals most likely to be involved in their use...
March 27, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29595893/postoperative-strategies-aimed-at-preventing-surgical-site-infections
#13
Lisa Hauk
No abstract text is available yet for this article.
April 2018: AORN Journal
https://www.readbyqxmd.com/read/29580355/a-cost-benefit-analysis-of-reducing-surgical-site-infections
#14
Alexander Rosemurgy, Jacqueline Whitaker, Kenneth Luberice, Christian Rodriguez, Darrell Downs, Sharona Ross
Surgical Site Infections (SSI) represent an onerous burden on our health-care system. This study was undertaken to determine the impact of a protocol aimed at reducing SSIs on the frequency and cost of SSIs after abdominal surgery. Beginning in 2013, 811 patients undergoing gastrointestinal operations were prospectively followed. In 2014, we initiated a protocol to reduce SSIs. SSIs were monitored before and after protocol implementation, and differences in SSI incidence and associated costs were determined...
February 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29578875/strategies-for-the-prevention-and-treatment-of-surgical-site-infection-in-the-lumbar-spine
#15
Joseph S Butler, Scott C Wagner, Patrick B Morrissey, Ian D Kaye, Arjun S Sebastian, Gregory D Schroeder, Kristen Radcliff, Alexander R Vaccaro
Surgical site infection (SSI) following spine surgery can be devastating for both the patient and the surgeon. It leads to significant morbidity and associated health care costs, from readmissions, reoperations, and subsequent poor clinical outcomes. Complications associated with SSI following spine surgery include pseudarthrosis, neurological deterioration, sepsis, and death. Its management can be very challenging. The diagnosis of SSI involves the interpretation of combined clinical, laboratory, and occasionally radiologic findings...
March 23, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29574803/preventive-effect-of-polynucleotide-on-post-thyroidectomy-scars-a-randomized-double-blinded-controlled-trial
#16
Ji Hee Kim, Jong Ju Jeong, Young In Lee, Won Jai Lee, Chorok Lee, Woong Youn Chung, Kee-Hyun Nam, Ju Hee Lee
BACKGROUND AND OBJECTIVE: Polynucleotide (PN) provides a structural scaffold to induce anti-inflammatory and enhanced wound healing properties, and this study aimed to assess the efficacy of PN administration in the prevention of post-operative scars after conventional open total thyroidectomy. STUDY DESIGN MATERIALS AND METHODS: Forty-two patients with thyroid carcinoma who underwent total thyroidectomy were randomly assigned to the study (PN administration) or control (normal saline) group...
March 25, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29572838/efficacy-of-prophylactic-probiotics-in-combination-with-antibiotics-versus-antibiotics-alone-for-colorectal-surgery-a-meta-analysis-of-randomized-controlled-trials
#17
REVIEW
Xiang-Dong Wu, Wei Xu, Meng-Meng Liu, Ke-Jia Hu, Ya-Ying Sun, Xue-Fei Yang, Gui-Qi Zhu, Zi-Wei Wang, Wei Huang
This meta-analysis aimed to determine whether prophylactic probiotics in combination with antibiotics are superior to antibiotics alone in the prevention of surgical site infection (SSI) after colorectal surgery. Fourteen trials involving 1524 participants were included. Compared with antibiotics alone, prophylactic probiotics in combination with antibiotics reduced the risk of SSI as well as other complications, shortened the cumulative duration of antibiotic therapy. Current evidence suggested that probiotics in combination with antibiotics could be recommended...
March 24, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29565953/unique-complications-of-percutaneous-endoscopic-lumbar-discectomy-and-percutaneous-endoscopic-interlaminar-discectomy
#18
Chuanli Zhou, Guoqing Zhang, Ripul R Panchal, Xianfeng Ren, Hongfei Xiang, Ma Xuexiao, Xiaoliang Chen, Gu Tongtong, Wang Hong, Alana D Dixson
BACKGROUND: Percutaneous endoscopic discectomy (PED) includes 2 main procedures: percutaneous endoscopic lumbar discectomy (PELD) and percutaneous endoscopic interlaminar discectomy (PEID), both of which are minimally invasive surgical procedures that effectively deal with lumbar degenerative disorders. Because of the challenging learning curve for the surgeon and the individual characteristics of each patient, preventing and avoiding complications is difficult. The most common complications, such as nucleus pulposus omission, nerve root injury, dural tear, visceral injury, nerve root induced hyperalgesia or burning-like nerve root pain, postoperative dysesthesia, posterior neck pain, and surgical site infection, are difficult to avoid; however, more focus on these issues perioperatively may be in order...
March 2018: Pain Physician
https://www.readbyqxmd.com/read/29561866/risk-prediction-for-staphylococcus-aureus-surgical-site-infection-following-cardiothoracic-surgery-a-secondary-analysis-of-the-v710-p003-trial
#19
Fleur P Paling, Karina Olsen, Kristin Ohneberg, Martin Wolkewitz, Vance G Fowler, Mark J DiNubile, Hasan S Jafri, Frangiscos Sifakis, Marc J M Bonten, Stephan J Harbarth, Jan A J W Kluytmans
BACKGROUND: Identifying patients undergoing cardiothoracic surgery at high risk of Staphylococcus aureus surgical site infection (SSI) is a prerequisite for implementing effective preventive interventions. The objective of this study was to develop a risk prediction model for S. aureus SSI or bacteremia after cardiothoracic surgery based on pre-operative variables. MATERIALS/METHODS: Data from the Merck Phase IIb/III S. aureus vaccine (V710-P003) clinical trial were analyzed...
2018: PloS One
https://www.readbyqxmd.com/read/29560408/postoperative-prophylactic-antibiotics-in-total-joint-arthroplasty
#20
Adolph J Yates
The Center for Disease Control and Prevention recently released their 2017 Guideline for the Prevention of Surgical Site Infection. One of their recommendations is the ordering of a single dose of preoperative prophylactic antibiotics with no subsequent postoperative dosing; this recommendation includes perioperative antibiotics for patients undergoing total joint arthroplasty. At this time, the American Association of Hip and Knee Surgeons (AAHKS) does not agree with this recommendation vis-a-vis total joint arthroplasty because it contradicts current international standards of care with limited evidence and study...
March 2018: Arthroplasty Today
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