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Tong Tang

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https://www.readbyqxmd.com/read/28637244/elevated-homocysteine-increases-the-risk-of-left-atrial-left-atrial-appendage-thrombus-in-non-valvular-atrial-fibrillation-with-low-cha2ds2-vasc-score
#1
Yan Yao, Mei-Sheng Shang, Li-Jian Gao, Jing-Hua Zhao, Xiao-Hui Yang, Tong Liu, Ri-Bo Tang, Chen-Xi Jiang, De-Yong Long, Man Ning, Hui Zhu, Qiang Lv, Rong Hu, Xin Du, Jian-Zeng Dong
Aims: To assess the association and the predictive value of plasma homocysteine (Hcy) levels with LA/LAA thrombus in non-valvular Atrial fibrillation (AF) patients with low CHA2DS2-VASc score. Methods and results: Eight hundred and eighty-eight consecutive patients in non-valvular AF with CHA2DS2-VASc score of 0 and 1 were enrolled. All patients routinely underwent transthoracic echocardiography and transoesophageal echocardiography. A total of thirty-two patients had LA/LAA thrombus...
June 16, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28624973/gracilibacillus-aidingensis-sp-nov-a-novel-moderately-halophilic-bacterium-isolated-from-aiding-salt-lake
#2
Tong-Wei Guan, Lei Tian, En-Yuan Li, Shu-Kun Tang, Xiao-Ping Zhang
A novel Gram-positive, aerobe, moderately halophilic bacterium was isolated from saline soil of Aiding lake in Xinjiang, north-west of China, designated strain YIM 98001(T). Cells were rod-shaped, motile and grew at 5-20% (w/v) NaCl (optimum 10%), pH 6-10 (optimum pH 7.0) and 4-45 °C (optimum 37 °C). The major cellular fatty acids were anteiso C15:0, anteiso C17:0, iso C15:0. The predominant respiratory quinone was MK-7. Diphosphatidylglycerol, phosphatidylglycerol, phosphoglycolipid were the major polar lipids...
June 17, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28621685/active-evolution-of-memory-b-cells-specific-to-viral-gh-gl-pul128-130-131-pentameric-complex-in-healthy-subjects-with-silent-human-cytomegalovirus-infection
#3
Lin Xia, Aimin Tang, Weixu Meng, Daniel C Freed, Linling He, Dai Wang, Fengsheng Li, Leike Li, Wei Xiong, Xun Gui, Robbie D Schultz, Haotai Chen, Xi He, Ryan Swoyer, Sha Ha, Yaping Liu, Charles D Morris, Yu Zhou, I-Ming Wang, Qinjian Zhao, Wenxin Luo, Ningshao Xia, Amy S Espeseth, Daria J Hazuda, Richard E Rupp, Alan D Barrett, Ningyan Zhang, Jiang Zhu, Tong-Ming Fu, Zhiqiang An
Human cytomegalovirus (HCMV) can cause life-threatening infection in immunosuppressed patients, and in utero infection that may lead to birth defects. No vaccine is currently available. HCMV infection in healthy subjects is generally asymptomatic, and virus persists as latent infection for life. Host immunity is effective against reactivation and super-infection with another strain. Thus, vaccine candidates able to elicit immune responses similar to those of natural infection may confer protection. Since neutralization is essential for prophylactic vaccines, it is important to understand how antiviral antibodies are developed in natural infection...
June 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/28608439/the-role-of-cold-inducible-rna-binding-protein-cirp-in-cell-stress-response
#4
REVIEW
Yi Liao, Lingying Tong, Liling Tang, Shiyong Wu
Cold-inducible RNA binding protein (CIRP) was discovered after the cells were exposed to a moderate cold shock because its production was induced. Other cellular stresses such as UV radiation and hypoxia also could increase its expression. Under stress conditions, CIRP could up regulate its own expression by self-transcriptional activation of alternative promoters. After relocating into cytoplasm from nucleus, CIRP assists cells in adapting to novel environmental conditions via stabilizing specific mRNAs and facilitating their translation...
June 12, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28596035/the-pharmacokinetic-and-pharmacodynamic-properties-of-site-specific-pegylated-genetically-modified-recombinant-human-interleukin-11-in-normal-and-thrombocytopenic-monkeys
#5
Shan-Shan Ma, Seong-Hyun Ho, Su-Yong Ma, Yue-Juan Li, Kai-Tong Li, Xiao-Chuang Tang, Guang-Rong Zhao, Song-Shan Xu
In order to improve the pharmacokinetic and pharmacodynamic properties of recombinant human interleukin-11 mutein (mIL-11) and to reduce the frequency of administration, we examined the feasibility of chemical modification of mIL-11 by methoxy polyethylene glycol succinimidyl carbonate (mPEG-SC). PEG-mIL-11 was prepared by a pH controlled amine specific method. Bioactivity of the protein was determined in a IL-11-dependent in vitro bioassay, its pharmacodynamic and pharmacokinetic properties were investigated by using normal and thrombocytopenic monkey models...
June 5, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28593346/the-first-identified-cathelicidin-from-tree-frogs-possesses-anti-inflammatory-and-partial-lps-neutralization-activities
#6
Lixian Mu, Lei Zhou, Juanjuan Yang, Li Zhuang, Jing Tang, Tong Liu, Jing Wu, Hailong Yang
As of February 2017, approximately 7639 amphibian species have been described in the AmphibiaWeb database. However, only 20 cathelicidin-like antimicrobial peptides have been identified to date from 10 amphibian species. Half of these peptides were identified from genome sequences and have not yet been functionally characterized. In this study, a novel cathelicidin-like peptide designated cathelicidin-PP was purified from the skin of tree frog Polypedates puerensis. Cathelicidin-PP is a 32 residue peptide of sequence ASENGKCNLLCLVKKKLRAVGNVIKTVVGKIA...
June 7, 2017: Amino Acids
https://www.readbyqxmd.com/read/28591966/-the-value-of-early-diastolic-transmitral-velocity-to-early-mitral-anulus-diastolic-velocity-ratio-for-pulmonary-edema-in-severe-sepsis-patients
#7
Wan-Hong Yin, Yi Li, Yao Qin, Yan Kang, Ji-Yuan Zhao, Tong-Juan Zou, Zhi-Yun Tang
OBJECTIVES: To determine the association between the value of early diastolic transmitral velocity to early mitral anulus diastolic velocity ratio (E/E')measured by bedside ultrasound and pulmonary edema in severe sepsis (including septic shock) patients. METHODS: Data were obtained from the critical ultrasound database between November 2014 and August 2015. The severe sepsis (including septic shock) patients were eligible, but those with chronic heart disease or acute heart failure were excluded...
July 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28578297/targeting-and-destroying-tumor-vasculature-with-a-near-infrared-laser-activated-nanobomb-for-efficient-tumor-ablation
#8
Wen Gao, Shuangshuang Li, Zhenhua Liu, Yuhui Sun, Wenhua Cao, Lili Tong, Guanwei Cui, Bo Tang
Attacking the supportive vasculature network of a tumor offers an important new avenue for cancer therapy. Herein, a near-infrared (NIR) laser-activated "nanobomb" was developed as a noninvasive and targeted physical therapeutic strategy to effectively disrupt tumor neovasculature in an accurate and expeditious manner. This "nanobomb" was rationally fabricated via the encapsulation of vinyl azide (VA) into c(RGDfE) peptide-functionalized, hollow copper sulfide (HCuS) nanoparticles. The resulting RGD@HCuS(VA) was selectively internalized into integrin αvβ3-expressing tumor vasculature endothelial cells and dramatically increased the photoacoustic signals from the tumor neovasculature, achieving a maximum signal-to-noise ratio at 4 h post-injection...
September 2017: Biomaterials
https://www.readbyqxmd.com/read/28577180/olivibacter-flavus-sp-nov-a-novel-endophytic-bacterium-isolated-from-the-root-of-camellia-sinensis
#9
Lei Tian, Tong-Wei Guan, Ling-Ling Yang, Kai-Yang Lu, Bing-Bing Liu, Wei-Xun ChunYu, Min Yin, En-Yuan Li, Yang Ji, Xiao-Ping Zhang, Shu-Kun Tang
A novel Gram-negative rod, endophytic bacterium, designated strain TMCC 8258(T), was isolated from the root of Camellia sinensis collected from Puer, south-west China. Comparative 16S rRNA gene sequence analysis showed that the strain belongs to the family Sphingobacteriaceae and a neighbour-joining phylogenetic tree suggested that strain TMCC 8258(T) formed a cluster with the type strain of Olivibacter ginsengisoli (showed the highest 16S rRNA gene sequence similarity of 95.8%). Chemotaxonomic data [major fatty acid iso-C15:0, summed feature 3 (C16:1 ω7c and/or C16:1 ω6c), iso-C17:0 3-OH and major respiratory quinone MK-7] confirmed the affiliation of strain TMCC 8258(T) to the genus Olivibacter...
June 2, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28573482/glycomyces-xinjiangensis-sp-nov-a-novel-actinomycete-isolated-from-a-hypersaline-habitat
#10
Tong-Wei Guan, Hui-Ping Xiang, Peng-Hao Wang, Lei Tian, Shu-Kun Tang, Shun-Xian Zhao, Xi-Chao Zhang
A novel actinomycete strain, designated XHU 5301(T), was isolated from a hypersaline habitat, China. The strain was aerobic, Gram-stain positive and the optimum NaCl concentration for growth was 7-9% (w/v). Phylogenetic analysis based on an almost-complete 16S rRNA gene sequence of strain XHU 5301(T) showed that the organism was most closely related to Glycomyces halotolerans TRM 40137(T) (96.0%). The whole-cell sugar pattern consisted of glucose and galactose. The predominant menaquinone was MK-10(H4), MK-10(H2), and MK-9(H4)...
June 1, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28558874/identification-of-c-geranylated-flavonoids-from-paulownia-catalpifolia-gong-tong-fruits-by-hplc-dad-esi-ms-ms-and-their-anti-aging-effects-on-2bs-cells-induced-by-h2o2
#11
Wen-Zhao Tang, Ying-Ai Wang, Tian-Yang Gao, Xiao-Jing Wang, Yun-Xue Zhao
The fruits of Paulownia catalpifolia Gong Tong are used as a Chinese folk herbal medicine for the treatment of enteritis, tonsillitis, bronchitis, and dysentery, etc. Our previous study has identified new C-geranylated flavanones with obvious anti-proliferative effects in lung cancer A549 cells. In the present study, a new C-geranylated flavone, paucatalinone C (1) and five known C-geranylated flavanones (2-6) were isolated. In addition, a total of 34 C-geranylated flavonoids were detected by HPLC-DAD-ESI-MS/MS coupling techniques from the CH2Cl2 extract of P...
May 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28556122/role-of-procalcitonin-in-differentiating-between-infectious-and-non-infectious-fevers-among-patients-with-lymphoma
#12
Xiao Jun Wang, Thuan Tong Tan, Soon Thye Lim, Mohamad Farid, Miriam Tao, Richard Quek, Alexandre Chan, Tiffany Tang
OBJECTIVE: The primary objective of this study is to prospectively evaluate the role of procalcitonin (PCT) in distinguishing infectious fever from non-infectious fever (NIF) among febrile lymphoma patients. The secondary objective is to evaluate the usefulness of PCT in distinguishing between bloodstream infections (BSI), local infections and unidentified infections (LIUI), and NIF. METHODS: Patients with lymphoma and fever were prospectively recruited between August 2014 and November 2015...
May 28, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28551548/quantitative-evaluation-of-atherosclerotic-plaques-and-intraplaque-neovascularization-using-contrast-enhanced-ultrasound-after-treatment-with-atorvastatin-in-rabbits
#13
Hong-Yu Liu, Jia Zhou, Hai Tong, Yan Tang, Xiao-Fang Wang, Qi-Chang Zhou
INTRODUCTION: This study is supposed to investigate the value of contrast-enhanced ultrasound (CEUS) in quantitative evaluation of atherosclerotic plaques and intraplaque neovascularization after treatment with atorvastatin (ATV) in rabbits. MATERIAL AND METHODS: Forty-five New Zealand white rabbits were enrolled to construct the rabbit model of AS. All rabbits were assigned into the control, AS group and ATV groups (n=15 individually). The AS plaque formation and relative parameters were observed and calculated by CEUS respectively...
August 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28551109/early-visual-analysis-tool-using-magnetoencephalography-for-treatment-and-recovery-of-neuronal-dysfunction
#14
Waqas Rasheed, Yee Yik Neoh, Nor Hisham Bin Hamid, Faruque Reza, Zamzuri Idris, Tong Boon Tang
Functional neuroimaging modalities play an important role in deciding the diagnosis and course of treatment of neuronal dysfunction and degeneration. This article presents an analytical tool with visualization by exploiting the strengths of the MEG (magnetoencephalographic) neuroimaging technique. The tool automates MEG data import (in tSSS format), channel information extraction, time/frequency decomposition, and circular graph visualization (connectogram) for simple result inspection. For advanced users, the tool also provides magnitude squared coherence (MSC) values allowing personalized threshold levels, and the computation of default model from MEG data of control population...
May 11, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28550390/clinical-patterns-and-characteristics-of-ankylosing-spondylitis-in-china
#15
Qiaoxia Qian, Xia Xu, Hongjun He, Hengdong Ji, Hui Zhang, Yue Ding, Sheng-Ming Dai, Yaohong Zou, Qi Zhu, Chengde Yang, Shuang Ye, Lindi Jiang, Jian-Ping Tang, Qiang Tong, Dongyi He, Dongbao Zhao, Yuan Li, Yanyun Ma, Jingru Zhou, Ziyu Yuan, Juan Zhang, Li Jin, Xiaodong Zhou, John D Reveille, Hejian Zou, Jiucun Wang
The study aimed to determine whether unique clinical patterns of AS may exist in China, specifically to explore the different clinical manifestations caused by gender, HLA-B27 status, and age at disease onset. The multicenter cross-sectional survey was conducted and 1251 patients were enrolled across China, representing a broad spectrum of Chinese AS patients. The mean age at onset and diagnosis were 29.2 (11.4) and 33.5 (12.6) years, respectively. The male/female ratio was 2.7:1. Acute anterior uveitis (AAU) was experienced in 10...
May 27, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28548944/the-adenosine-a2b-receptor-promotes-tumor-progression-of-bladder-urothelial-carcinoma-by-enhancing-mapk-signaling-pathway
#16
Yihong Zhou, Xi Chu, Fei Deng, Liang Tong, Guoxiong Tong, Ye Yi, Jianye Liu, Jin Tang, Yuxin Tang, Yang Xia, Yingbo Dai
The adenosine A2b receptor (A2bR) was considered to play an oncogenic role in many human malignancies. However, the expression and molecular function of A2bR in bladder urothelial carcinoma (BUC) have not been well elucidated. Herein, we found that the expression of A2bR was higher than other adenosine receptors in BUC tissues and cells, and it was upregulated in BUC tissues compared with matched normal bladder tissues. Furthermore, high expression of A2bR was associated with poor prognosis of patients with BUC...
May 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28541352/copper-i-mediated-carboamination-of-vinyl-azides-by-aryldiazonium-salts-synthesis-of-n-2-substituted-1-2-3-triazoles
#17
Zhenhua Liu, Huimin Ji, Wen Gao, Guangyu Zhu, Lili Tong, Fengcai Lei, Bo Tang
A copper(i)-mediated carboamination cascade reaction between vinyl azides and aryldiazonium salts is described. Functionally diverse N(2)-substituted 1,2,3-triazoles were obtained in moderate to good yields through novel difunctionalization of vinyl azides by aryldiazonium salt sources. This method has a wide scope, good functional-group tolerance and insensitivity to an ambient atmosphere.
June 6, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28535566/the-analgesic-effects-of-celecoxib-on-the-formalin-induced-short-and-long-term-inflammatory-pain
#18
Ya-Qun Zhao, Hai-Yan Wang, Jun-Bin Yin, Yan Sun, Yong Wang, Jin-Chuan Liang, Xiao-Ju Guo, Ke Tang, Yu-Tong Wang
The non-steroidal anti-inflammatory drug celecoxib has long been used for reducing pain, in spite of moderate gastrointestinal side effects. In previous studies, it has been shown that celecoxib can inhibit formalin-induced spontaneous pain and secondary hyperalgesia. Injecting formalin into a rodent's hind paw not only induces acute pain behaviors, but also produces long-lasting hyperalgesia. Whether celecoxib can also have long-lasting effects is still unknown. Our results show that pretreatment with an intraperitoneal injection of celecoxib at one hour before formalin injection induced inhibition on the spontaneous flinch and licking behaviors in the second phase but not the first phase...
May 2017: Pain Physician
https://www.readbyqxmd.com/read/28535433/a-highly-selective-surface-coating-for-enhanced-membrane-rejection-of-endocrine-disrupting-compounds-mechanistic-insights-and-implications
#19
Hao Guo, Yu Deng, Zhikan Yao, Zhe Yang, Jianqiang Wang, Chuner Lin, Tong Zhang, Baoku Zhu, Chuyang Y Tang
We designed a highly selective surface coating to achieve enhanced rejection of endocrine disrupting compounds (EDCs) by nanofiltration membranes. A commercial NF90 membrane was first coated with polydopamine (PDA) followed by in situ immobilization of silver nanoparticles (AgNPs). This PDA/AgNPs coating greatly improved EDC rejection at the expense of slight water permeability loss (4-10%). This improvement in rejection can be attributed to a combination of enhanced size exclusion and suppressed hydrophobic interaction...
May 18, 2017: Water Research
https://www.readbyqxmd.com/read/28528230/effect-of-childhood-trauma-on-cognitive-functions-in-a-sample-of-chinese-patients-with-schizophrenia
#20
Xian-Bin Li, Qi-Jing Bo, Guang-Ping Zhang, Wei Zheng, Zhi-Min Wang, An-Ning Li, Qing Tian, Jin-Tong Liu, Yi-Lang Tang, Chuan-Yue Wang
In this study, we aimed to determine the influence of various types of childhood trauma (CT) on cognitive functions in Chinese patients presented with schizophrenia. One hundred sixty-two patients were assessed with the Childhood Trauma Questionnaire-Short Form (CTQ-SF) and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). We investigated the correlations between various types of CT, demographic characteristics, and cognitive functions. Significant negative correlations were observed in physical abuse (PA) and sexual abuse (SA) with the language score (r=-0...
July 2017: Comprehensive Psychiatry
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