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Boman Chen, Min Cheng, Siqi Hong, Shuang Liao, Jiannan Ma, Tingsong Li, Li Jiang
PURPOSE: To assess the clinical outcome and evolution of recurrent afebrile seizures in children initially diagnosed with benign convulsions associated with mild gastroenteritis (CwG). METHODS: We reviewed and analyzed the medical records of 37 patients who were diagnosed as CwG at onset, followed by recurrent afebrile seizures and followed up for at least 24 months. RESULTS: The follow-up period ranged from 2 to 7 years (median, 40.1 months)...
May 30, 2018: Seizure: the Journal of the British Epilepsy Association
Jacob Robson, Molly O'Gorman, Amber McClain, Krishna Mutyala, Cassandra Davis, Carlos Barbagelata, Justin Wheeler, Rafael Firszt, Ken Smith, Raza Patel, Kathryn Peterson, Amy Lowichik, Stephen Guthery
BACKGROUND & AIMS: Eosinophilic esophagitis (EoE) is often detected in children and is considered to be a rare disease, with prevalence values reported to be below 60 cases per 100,000 persons. To determine whether the incidence of EoE in children in Utah exceeds estimates from regional reports, we calculated incidence and prevalence values over a 5-year period. METHODS: Using consensus guidelines for the diagnosis of EoE, we reviewed pathology records from in the Intermountain Healthcare pathology database, from July 1, 2011 through June 31, 2016...
June 20, 2018: Clinical Gastroenterology and Hepatology
Marcos Dellaretti, Daniel Ronconi, Danilo Malta Batista, Renata Ferreira de Souza, Carlos Eduardo Romeu de Almeida, Renato Rinco Fontoura, Paulo Ramos Botelho Antunes, Ricardo Sousa Quadros
BACKGROUND: Nowadays, the use of microsurgery for clipping aneurysms has decreased considerably. OBJECTIVE: To demonstrate the safety and effectiveness of surgical treatment of intracranial aneurysms even in less developed countries. METHODS: Retrospective review of the medical records of 320 patients with 416 aneurysms treated with microsurgical clipping from 2008 to 2016 in a single neurosurgical center in Brazil. This study evaluated postoperative outcome, using the modified Rankin Scale (mRS) on hospital discharge, treatment efficacy, assessed by digital subtraction angiography (DSA) performed postoperatively, and mortality...
June 20, 2018: World Neurosurgery
Ana L Creo, Bryan C Cannon, Siobhan T Pittock
BACKGROUND: A thyroid storm (TS) is a rare, but life-threatening condition in hyperthyroid patients. Mortality in adult TS patients may be as high as 10%. Typically, a trigger precipitates the storm in hyperthyroid patients. CASE PRESENTATION: We report the case of an adolescent girl with untreated hyperthyroidism who developed fulminant TS after a significant choking episode. Initially, she was found to have neck swelling and tachycardia leading providers to suspect infection...
June 23, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
P Kanzow, N Schuelper, D Witt, T Wassmann, S Sennhenn-Kirchner, A Wiegand, T Raupach
INTRODUCTION: Various scoring approaches for Multiple True-False (MTF) items exist. This study aimed at comparing scoring results obtained with different scoring approaches and to assess the effect of item cues on each scoring approaches' result. MATERIALS AND METHODS: Different scoring approaches (MTF, Count-2, Count-3, "Vorkauf-Method," PS50 , Dichotomized MTF, "Blasberg-Method," Multiple response (MR), Correction for Guessing, "Ripkey-Method," Morgan-Method, Balanced Scoring Method) were retrospectively applied to all MTF items used within electronic examinations of undergraduate dental students at the University Medical Center Göttingen in the winter term 2016/2017 (1297 marking events)...
June 22, 2018: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
Michele Wilson, Matt Wasserman, Taj Jadavi, Maarten Postma, Marie-Claude Breton, Francois Peloquin, Stephanie Earnshaw, Cheryl McDade, Heather Sings, Raymond Farkouh
INTRODUCTION: Pneumococcal conjugate vaccines (PCVs) have been available in Canada since 2001, with 13-valent PCV (PCV13) added to the infant routine immunization program throughout all Canadian provinces by 2011. The use of PCVs has dramatically reduced the burden of pneumococcal disease in Canada. As a result, decision-makers may consider switching from a more costly, higher-valent vaccine to a lower-cost, lower-valent vaccine in an attempt to allocate funds for other vaccine programs...
June 22, 2018: Infectious Diseases and Therapy
Markus Bruder, Sepide Kashefiolasl, Fee Keil, Nina Brawanski, Sae-Yeon Won, Volker Seifert, Juergen Konczalla
Acetylsalicylic acid (ASA) is a well-known and widely used analgesic for acute pain. Patients with acute headache due to subarachnoid hemorrhage (SAH) are inclined to take ASA in this situation. Due to the antithrombotic effects, ASA intake is related to higher bleeding rates in case of hemorrhage or surgical treatment. Between January 2006 and December 2016, 941 patients without continuous antithrombotic or anticoagulant medication were treated due to SAH in our institution. Fourteen of them (1.5%) had taken ASA as a single dose because of headache within 24 h before hospital admission...
June 22, 2018: Neurosurgical Review
T Godel, M Pham
CLINICAL/METHODICAL ISSUE: Entrapment syndromes of peripheral nerves at the elbow are common and are often diagnostically challenging disorders. Difficulties consist in lesion localization and recognition of complex spatial lesion patterns as well as in differentiation of focal and multifocal disorders. STANDARD DIAGNOSTIC METHODS: Medical history taking, neurological examination and neurophysiological tests represent the gold standard in the diagnosis of peripheral nerve lesions at the elbow, but have known methodical limitations...
June 22, 2018: Der Radiologe
Anne G Sammarco, Daniel M Morgan, Neil S Kamdar, Carolyn W Swenson
OBJECTIVES: To (1) determine the proportion of hysterectomy cases with documentation of pessary counseling prior to prolapse surgery and (2) identify variables associated with women offered a pessary. STUDY DESIGN: The Michigan Surgical Quality Collaborative (MSQC) is a hysterectomy improvement initiative. Hysterectomies from 2013 to 2015 in which prolapse was the principal diagnosis were included. "Pessary offer" was defined as documentation showing the patient declined, could not tolerate, or failed a pessary trial...
June 22, 2018: International Urogynecology Journal
Stephanie Padberg, Christoph Bührer, Juliane Menzel, Cornelia Weikert, Christof Schaefer, Klaus Abraham
Although breast milk is the best diet in the first few months of life, risks can arise for the breast-fed infant. The article gives a comprehensive overview of possible risks regarding xenobiotics and pathogens in mother's milk, including medications, smoking, alcohol consumption, coffee consumption, persistent environmental contaminants and residues as well as infections.Where drug therapy is indicated, suitable medications are available for most conditions nowadays, so that prolonged nursing breaks or even weaning is not required...
June 22, 2018: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Mohammad Abdelghani, Martina Nassif, Nico A Blom, Martijn S Van Mourik, Bart Straver, David R Koolbergen, Jolanda Kluin, Jan G Tijssen, Barbara J M Mulder, Berto J Bouma, Robbert J de Winter
BACKGROUND: Infective endocarditis (IE) after transcatheter pulmonary valve implantation (TPVI) in dysfunctioning right ventricular outflow tract conduits has evoked growing concerns. We aimed to investigate the incidence and the natural history of IE after TPVI with the Melody valve through a systematic review of published data. METHODS AND RESULTS: PubMed, EMBASE, and Web of Science databases were systematically searched for articles published until March 2017, reporting on IE after TPVI with the Melody valve...
June 22, 2018: Journal of the American Heart Association
Leslie Martin, Ameen Patel, Katrina Piggott, Arthur Wong, Alexandra Patel, Matthew Patel, Yudong Liu, Sukhbinder Dhesy-Thind, Parveen Wasi, John J You
BACKGROUND: Allied health care professionals can contribute meaningfully to goals-of-care discussions with seriously ill hospitalized patients and their families. We sought to explore the perspective of hospital-based allied health care professionals on their role in goals-of-care discussions and to identify barriers to their participation. METHODS: We surveyed allied health care professionals (social workers, physiotherapists, occupational therapists, registered dietitians, speech-language pathologists and pharmacists) on internal medicine, hematology-oncology, medical oncology and radiation oncology wards at 2 tertiary care hospitals in Hamilton, Ontario, from April 2013 to May 2014...
April 2018: CMAJ Open
Ralph M Turner, Qinli Ma, Kate Lorig, Jay Greenberg, Andrea R DeVries
BACKGROUND: An estimated 30.3 million Americans have diabetes mellitus. The US Department of Health and Human Services created national objectives via its Healthy People 2020 initiative to improve the quality of life for people who either have or are at risk for diabetes mellitus, and hence, lower the personal and national economic burden of this debilitating chronic disease. Diabetes self-management education interventions are a primary focus of this initiative. OBJECTIVE: The aim of this study was to evaluate the impact of the Better Choices Better Health Diabetes (BCBH-D) self-management program on comorbid illness related to diabetes mellitus, health care utilization, and cost...
June 22, 2018: Journal of Medical Internet Research
Su Young Jung, Hyung-Sik Kim, Jin-Young Min, Kyoung Jin Hwang, Sung Wan Kim
OBJECTIVE: Sleep hygiene-related conditions are factors that affect the symptoms experienced by patients with obstructive sleep apnea (OSA). However, very few studies have investigated the association between sleep hygiene and sleep symptoms, especially in patients with mild or moderate OSA. This study evaluated the relationship between factors related to sleep hygiene and clinical symptoms in patients with mild to moderate OSA. METHODS: One hundred and seventy-four patients who visited the Sleep Breathing Disorder Center at a tertiary academic center to evaluate suspected OSA were included...
June 19, 2018: Auris, Nasus, Larynx
Verónica Vidal, Cristina Albiach, Josep Gradolí, José Leandro Pérez, Vicente Montagud, Joaquina Belchí, Salvador Morell, Lorenzo Fácila
Prosthetic valve endocarditis is a major diagnostic challenge in clinical practice, due to the lower sensitivity of the modified Duke criteria and a higher percentage of cases with negative or inconclusive echocardiography results. The delay in establishing medical and surgical treatment increases the morbidity/mortality rate. New imaging techniques and 18F-FDG PET/CT in particular have meant a significant advance in cases of high clinical suspicion and negative or inconclusive echocardiography, increasing the overall sensitivity of the modified Duke criteria...
June 19, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Geraud Souteyrand, Louis Viallard, Nicolas Combaret, Bruno Pereira, Guillaume Clerfond, Guilhem Malcles, Nicolas Barber Chamoux, Francesco Prati, Pascal Motreff
BACKGROUND: A two-step strategy of invasive management without stenting, guided by optical coherence tomography (OCT), in selected patients with acute coronary syndrome (ACS), might avoid systematic stent implantation and allow medical therapy alone. AIMS: To assess the feasibility and safety of such a procedure, and to define coronary imaging characteristics in a specific population. METHODS: This single-centre proof-of-concept study included all patients with ACS who benefited from a two-step revascularization procedure with optimal reperfusion during primary percutaneous coronary intervention followed by delayed angiography and OCT...
June 19, 2018: Archives of Cardiovascular Diseases
Sarah Kleemann, Ian Mosley, Mark Fitzgerald
BACKGROUND: Traumatic spinal cord injury (SCI) is a devastating injury, frequently resulting in paralysis and a lifetime of medical and social problems. Reducing time to surgery may improve patient outcomes. A vital first step to reduce times is to map current pathways of care from injury to surgery, identify rapid care pathways and factors associated with rapid care pathway times. METHODS: A retrospective review of the Alfred Trauma Service records was undertaken for all cases of spinal injury recorded in the Alfred Trauma Registry over a three year period...
June 18, 2018: Injury
Brandon C Perry, Christopher R Ingraham, Brent K Stewart, Karim Valji, Kalpana M Kanal
RATIONALE AND OBJECTIVES: To assess the implementation of radiation dose monitoring software, create a process for clinical follow-up and documentation of high-dose cases, and quantify the number of patient reported radiation-induced tissue reactions in fluoroscopically guided interventional radiology (IR) and neuro-interventional radiology (NIR) procedures. MATERIALS AND METHODS: Web-based radiation dose monitoring software was installed at our institution and a process to flag all procedures with reference point air kerma (Ka,r ) > 5000 mGy was implemented...
June 19, 2018: Academic Radiology
Catherina Zadeh, Loubna Tayara
AIM: Tuberculosis is a contagious disease caused by Mycobacterium tuberculosis. It represents, according to WHO, one of the most leading causes of death worldwide.1 BACKGROUND: Based on our regional conditions, such as Syrian immigration, poor nutritional status, are contributors for the development of the disease. METHODS: This was a retrospective analytical cross sectional study done to review all cases of tuberculosis newly diagnosed at RHUH during 10 years period (2005-2015)...
July 2018: Indian Journal of Tuberculosis
Francky Teddy Endomba, Charlie Romain Mbega, Joel Noutakdie Tochie, Saint-Just N Petnga
BACKGROUND: Giant congenital melanocytic nevus is a very rare condition characterized by a large skin lesion and an increased risk of complications like neurocutaneous melanosis and malignant transformation. Reports of giant congenital melanocytic nevus are scarce in the sub-Saharan African literature and here we present a case of this disease in a Cameroonian adolescent. CASE PRESENTATION: A 12-year-old Cameroonian girl from the "Baka" ethnic group, with no relevant family and medical histories presented with a progressively extensive brownish-black nodular hypertrophic skin lesion of approximately 45 cm, which she had had since she was 2-days old...
June 23, 2018: Journal of Medical Case Reports
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