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Apneas hypopnea

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https://www.readbyqxmd.com/read/29351040/respiratory-polysomnographic-findings-in-patients-treated-primarily-for-unilateral-cleft-lip-and-palate
#1
Davi Sandes Sobral, Gustavo Juliane Faller, Marcus Vinícius Martins Collares
Cleft lip and palate (CLP) is the most common congenital craniofacial abnormality. Obstructive sleep apnea syndrome (OSAS) is a highly prevalent but underdiagnosed disease and is frequently associated with craniofacial anomalies. There are few studies describing the sleep breathing pattern of children with CLP. This study sought to characterize the respiratory profile of 23 children with unilateral cleft lip and palate, aged 7-12 years, who had undergone cleft lip and nasal repair at age 3-4 months and palatoplasty at 12-15 months, with a particular focus on evaluating the presence of OSAS in children with CLP...
February 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29351000/age-effects-on-cerebral-oxygenation-and-behavior-in-children-with-sleep-disordered-breathing
#2
Knarik Tamanyan, Lisa M Walter, Aidan Weichard, Margot J Davey, Gillian M Nixon, Sarah N Biggs, Rosemary Sc Horne
RATIONALE: Childhood sleep disordered breathing ranges in severity from primary snoring to obstructive sleep apnea and is associated with behavioral and neurocognitive deficits. It remains unknown why children with primary snoring, who do not experience peripheral oxygen desaturation or sleep fragmentation, experience similar daytime deficits as those with obstructive sleep apnea or why effects are age dependent. OBJECTIVE: To examine cerebral tissue oxygenation and oxygen extraction as an explanation for daytime deficits in children with primary snoring...
January 19, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29344749/diagnosis-of-sleep-apnea-in-patients-with-stable-chronic-heart-failure-using-a-portable-sleep-test-diagnostic-device
#3
Inês Araújo, Filipa Marques, Sandra André, Manuel Araújo, Sara Marques, Rita Ferreira, Patrícia Moniz, Margarida Proença, Pedro Borrego, Cândida Fonseca
PURPOSE: ApneaLink is a portable device for the screening of sleep apnea, a prevalent and underdiagnosed comorbidity in heart failure patients. A prospective cross-sectional study in patients with chronic heart failure was carried out to assess the sensitivity and specificity of apnea-hypopnea index (AHI) measurements using ApneaLink against the standard polysomnography test. METHODS: Adult patients with a prior hospitalization in an acute heart failure hospital unit were recruited for the study...
January 17, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29343998/rationale-and-design-for-a-monocentric-prospective-study-sleep-apnea-diagnosis-using-a-novel-pacemaker-algorithm-and-link-with-aldosterone-plasma-level-in-patients-presenting-with-diastolic-dysfunction-sapaad-study
#4
Laure Champ-Rigot, Virginie Ferchaud, Jean-Noël Prévost, Pierre Moirot, Arnaud Pellissier, Damien Legallois, Joachim Alexandre, Patrice Scanu, Remy Morello, Eric Saloux, Paul Ursmar Milliez
Previous studies showed good agreement between pacemaker respiratory disturbance index (RDI) and polysomnography for diagnosis of severe sleep apnea (SA). The aim of this study is to investigate the diagnostic accuracy of RDI compared with apnea-hypopnea index (AHI) from a cardiorespiratory sleep study for the diagnosis of severe SA within patients requiring a pacemaker and meeting diastolic dysfunction criteria. Secondary objectives are as follows: correlation between plasma aldosterone level and SA severity, diagnostic accuracy of RDI for moderate SA, prevalence of SA among patients with diastolic dysfunction, occurrence of arrhythmias, and improvement of RDI with continuous positive airway pressure therapy...
2018: Clinical Medicine Insights. Cardiology
https://www.readbyqxmd.com/read/29343019/-advances-in-preoperative-screening-of-obstructive-sleep-apnea-hypopnea-syndrome
#5
S Zhang, H Liu, S M Qing
No abstract text is available yet for this article.
January 12, 2018: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29340766/wanted-a%C3%A2-better-cut-off-value-for-the-epworth-sleepiness-scale
#6
Karin Trimmel, Magdalena Żebrowska, Marion Böck, Andrijana Stefanic, Daniel Mayer, Gerhard Klösch, Eduard Auff, Stefan Seidel
BACKGROUND: Excessive daytime sleepiness (EDS) is the main complaint in many neurological sleep disorders, such as idiopathic hypersomnia, narcolepsy, or obstructive sleep apnea/hypopnea syndrome (OSAS). The validity of the Epworth Sleepiness Scale (ESS) as a screening tool for EDS remains controversial. We therefore investigated (1) the interrelation of the ESS total score and the mean sleep latency (MSL) during the multiple sleep latency test (MSLT) and (2) the diagnostic accuracy of the ESS total score to detect EDS in patients with the chief complaint of subjective EDS...
January 16, 2018: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29340495/validation-of-the-stop-bang-questionnaire-as-a-means-of-screening-for-obstructive-sleep-apnea-in-adults-in-brazil
#7
Ricardo Luiz de Menezes Duarte, Lorena Barbosa de Moraes Fonseca, Flavio José Magalhães-da-Silveira, Erika Aparecida da Silveira, Marcelo Fouad Rabahi
OBJECTIVE: To validate the Portuguese-language version of the STOP-Bang (acronym for Snoring, Tiredness, Observed apnea, high blood Pressure, Body mass index, Age, Neck circumference, and Gender) questionnaire, culturally adapted for use in Brazil, as a means of screening for obstructive sleep apnea (OSA) in adults. METHODS: In this validation study, we enrolled patients ≥ 18 years of age, recruited between May of 2015 and November of 2016. All patients completed the STOP-Bang questionnaire and underwent overnight polysomnography...
November 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29339206/objective-sleep-measures-in-subacute-stroke-inpatients-associated-with-levels-and-improvements-in-activities-of-daily-living
#8
Ren-Jing Huang, Ching-Hsiang Lai, Shin-Da Lee, Fang-Yu Pai, Shen-Wen Chang, Ai-Hui Chung, Yi-Fang Chang, Hua Ting
OBJECTIVE: To investigate whether objective polysomnographic measures of prevalent sleep problems such as sleep-disordered-breathing (SDB) and insomnia are associated with activities of daily living levels in inpatients at rehabilitation units DESIGN: Retrospective and observational study SETTING: Single rehabilitation center PARTICIPANTS: One hundred twenty-three enrolled subacute stroke inpatients (61.6 ± 13.1 years; 23.8 ± 3.4 kg/m2; 33% female; 90.5 ± 36.7 days post-stroke) underwent a one-night polysomnography study and one-month-long inpatient rehabilitation program...
January 12, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29339193/a-pilot-study-on-the-biomechanical-assessment-of-obstructive-sleep-apnea-pre-and-post-bariatric-surgery
#9
Ahmed M Al-Jumaily, Sherif Ashaat, Bryn Martin, Rachael Pohle-Krauza, Matthew Krauza, Adrian Dan, John Zografakis
Obesity is a major risk factor for obstructive sleep apnea patients. In obese patients the severity of this risk can be reduced by bariatric surgery. This pilot study investigates the perioperative effects of bariatric surgery on obstructive sleep apnea and on the physical and biomechanical characteristics of the upper airway. Polysomnography and computer tomography data for 10 morbid obese patients promoted for bariatric surgery were conducted before surgery and at 6 and 12 months postoperatively for assessment of the oropharyngeal anatomy, and subsequent three-dimensional modelling of the airway...
January 12, 2018: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29338120/the-association-between-different-features-of-sleep-disordered-breathing-and-blood-pressure-a-cross-sectional-study
#10
Shayan Khoshkish, Mathias Hohl, Benedikt Linz, Michael Arzt, Felix Mahfoud, Mathias Baumert, Jakob Schöpe, Michael Böhm, Dominik Linz
Sleep disordered breathing (SDB) is highly prevalent in patients with high blood pressure (BP). Severity of SDB can be evaluated by the number of apneas and hypopneas per hour (AHI) or by measures of hypoxia. The objective of this study was to assess the association between different measures of SDB and BP. In 134 consecutive patients, polygraphy was performed to determine the AHI. Pulse oximetry was used to determine hypoxemic burden (time below 90% oxygen saturation [T90] and hypoxia load [HL], representing the integrated area above the curve of desaturation)...
January 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29332687/similarities-and-differences-in-estimates-of-sleep-duration-by-polysomnography-actigraphy-diary-and-self-reported-habitual-sleep-in-a-community-sample
#11
Karen A Matthews, Sanjay R Patel, Elizabeth J Pantesco, Daniel J Buysse, Thomas W Kamarck, Laisze Lee, Martica H Hall
OBJECTIVES: To compare estimates of sleep duration defined by polysomnography (PSG), actigraphy, daily diary, and retrospective questionnaire and to identify characteristics associated with differences between measures. DESIGN: Cross-sectional. SETTING: Community sample. PARTICIPANTS: The sample consisted of 223 Black, White, and Asian middle- to older-aged men and women residing in the Pittsburgh, PA area. INTERVENTIONS: Not applicable...
February 2018: Sleep Health
https://www.readbyqxmd.com/read/29330970/gamma-glutamyl-transferase-activity-as-a-predictive-marker-for-severity-of-obstructive-sleep-apnea-syndrome-and-concomitant-hypertension
#12
Bozkus Fulsen
BACKGROUND: Chronic intermittent hypoxia, inflammation and oxidative stress are involved in resultant obstructive sleep apnea syndrome (OSAS), which may affect numerous regulatory mechanisms that play a role in the regulation of blood pressure. Gamma glutamyl transferase (GGT) is a novel marker in the prediction of cardiovascular risk. OBJECTIVE: The objective of this study was to investigate the correlation of serum levels of GGT with hypertension and the degree of the upper airway obstruction in subjects with OSAS...
January 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29330769/comorbid-insomnia-and-sleep-apnea-in-veterans-with-post-traumatic-stress-disorder
#13
Ali A El-Solh, David Adamo, Thomas Kufel
PURPOSE: The purpose of this study was to determine the impact of insomnia in Veterans with post-traumatic stress disorder (PTSD) and obstructive sleep apnea (OSA) on health-related outcomes before and after 12 weeks of continuous positive airway pressure (CPAP) treatment. METHODS: We conducted a prospective cohort study of Veterans with PTSD and documented apnea hypopnea index (AHI) ≥ 5 with and without clinically significant insomnia as determined by the Insomnia Severity Index (ISI)...
January 10, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29327348/respiratory-dysfunction-progresses-with-age-in-kcna1-null-mice-a-model-of-sudden-unexpected-death-in-epilepsy
#14
Kristina A Simeone, Jodi Hallgren, Charles S Bockman, Ankita Aggarwal, Vikash Kansal, Lauren Netzel, Shruthi H Iyer, Stephanie A Matthews, Malavika Deodhar, Peter J Oldenburg, Peter W Abel, Timothy A Simeone
OBJECTIVE: Increased breathing rate, apnea, and respiratory failure are associated with sudden unexpected death in epilepsy (SUDEP). We recently demonstrated the progressive nature of epilepsy and mortality in Kcna1-/- mice, a model of temporal lobe epilepsy and SUDEP. Here we tested the hypothesis that respiratory dysfunction progresses with age in Kcna1-/- mice, thereby increasing risk of respiratory failure and sudden death (SD). METHODS: Respiratory parameters were determined in conscious mice at baseline and following increasing doses of methacholine (MCh) using noninvasive airway mechanics (NAM) systems...
January 12, 2018: Epilepsia
https://www.readbyqxmd.com/read/29327119/nocturnal-hypoxemic-burden-is-associated-with-epicardial-fat-volume-in-patients-with-acute-myocardial-infarction
#15
Dominik Linz, Stefan Colling, Wolfgang Nußstein, Kurt Debl, Mathias Hohl, Claudia Fellner, Michael Böhm, Lars S Maier, Okka W Hamer, Stefan Buchner, Michael Arzt
BACKGROUND: Increased epicardial fat volume (EFV) is a common feature of patients with sleep-disordered breathing (SDB), is considered as an established marker of cardiovascular risk, and is associated with adverse cardiovascular events after myocardial infarction (MI). METHODS: To investigate the association between different measures of SDB severity and EFV after acute MI, we enrolled 105 patients with acute MI in this study. Unattended in-hospital polysomnography was performed to determine the number of apneas and hypopneas per hour during sleep (apnea-hypopnea index, AHI)...
January 11, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29325335/-association-between-serum-adipocyte-fatty-acid-binding-protein-level-and-insulin-resistance-in-patients-with-osas
#16
Y B Wang, X F Li, R Chen, J H Shen, Y H Zhang
Objective: To investigate the association between serum adipocyte fatty acid binding protein (A-FABP) level and insulin resistance in patients with obstructive sleep apnea syndromes (OSAS). Methods: Eighty patients with snoring were monitored by overnight polysomnography (PSG) from September 2015 to July 2017, and there were 59 males and 21 females, aged from 22 to 77 years old (mean age 47±14 years old). Based on the apnea-hypopnea index (AHI), these patients were divided into three groups: primary snoring group (AHI<5/h, n=19), mild-moderate OSAS groups (5/h≤AHI≤30/h, n=23) and severe OSAS groups (AHI>30/h, n=38)...
December 26, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29325332/-gender-differences-of-rem-related-obstructive-sleep-apnea-hypopnea-syndrome
#17
M Xie, R Ren, J M He, X F Xue, T M Li, L Tan, F Lei, X D Tang, L H Yang
Objective: To explore the gender differences of rapid-eye-movement (REM) related obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: Consecutive patients with primary complaint of snoring from Sleep Medicine Center of West China Hospital between January 2016 and November 2016 were included in the study. All participants underwent one night polysomnography (PSG) and Epworth sleep scale (ESS) was estimated. The patients diagnosed with OSAHS were classified as REM related OSAHS (REM-OSAHS group) and non-rapid-eye-movement (NREM) related OSAHS (NREM-OSAHS group) based on the PSG parameters...
December 26, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29322708/high-prevalence-of-obstructive-sleep-apnea-among-people-with-type-2-diabetes-mellitus-in-a-tertiary-care-center
#18
Vijay Viswanathan, Indira Priyadarshini Ramalingam, Nagarajan Ramakrishnan
Purpose: Untreated obstructive sleep apnea (OSA) is a risk factor for hypertension and cardiac events, and is associated with increased mortality. Recent studies indicate that majority of people with type 2 diabetes also has OSA. The aim of this study was to assess the prevalence and severity of OSA and risk factors contributing to it among people with chronic and severe type 2 diabetes. Methods: A total of 203 people with type 2 diabetes (mean age: 54±8 years, 145 males, 58 females, HbA1c ≥7% [53mmol/mol]) attending a diabetes specialty hospital were included in the study; all were subjected to comprehensive diabetic evaluation and Apnea Hypopnea Index (AHI) was used to evaluate OSA...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29321408/the-factors-affecting-the-non-dipper-pattern-in-japanese-patients-with-severe-obstructive-sleep-apnea
#19
Hiromitsu Sekizuka, Naohiko Osada, Yoshihiro J Akashi
Objective Obstructive sleep apnea (OSA) is assumed to influence the circadian blood pressure (BP) fluctuation, particularly causing nocturnal hypertension and changing the dipping pattern of nocturnal BP. This study aimed to clarify the triggers of the non-dipper pattern in nocturnal BP in Japanese patients with severe OSA (the apnea-hypopnea index ≥30/h). Methods Of 541 patients with OSA diagnosed using polysomnography (PSG) and ambulatory BP monitoring (ABPM), 163 patients <60 years of age (Younger group) and 101 patients ≥60 years of age (Older group) were stratified into the dipper or non-dipper pattern groups...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29319596/obstructive-sleep-apnea-assessed-by-overnight-polysomnography-in-patients-with-keratoconus
#20
Emilio Pedrotti, Christian Luigi Demasi, Adriano Fasolo, Erika Bonacci, Tommaso Brighenti, Nicola Gennaro, Marcello Ferrari, Giorgio Marchini
PURPOSE: To determine the prevalence of obstructive sleep apnea (OSA) in patients with keratoconus (KCN) and to evaluate the association between the severity of KCN and OSA. METHODS: OSA was diagnosed with an overnight home sleep apnea test. As estimated by home monitoring, an apnea-hypopnea index threshold of ≥5 sleep-related obstructive breathing events per hour was considered suggestive of OSA. For grading KCN severity (Amsler-Krumeich classification), slit-lamp biomicroscopy, corneal topography, and pachymetry measurements were performed...
January 9, 2018: Cornea
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