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MR Plaque

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https://www.readbyqxmd.com/read/28629953/3d-black-blood-mr-angiography-of-the-carotid-arteries-a-simple-sequence-for-plaque-hemorrhage-and-stenosis-evaluation
#1
Monica Sigovan, Clément Bidet, Sébastien Bros, Loic Boussel, Laura Mechtouff, Philip M Robson, Zahi A Fayad, Antoine Millon, Philippe Douek
OBJECTIVES: To evaluate the diagnostic performance of a new three-dimensional T1-weighted turbo-spin-echo sequence (3D T1-w TSE) compared to 3D contrast-enhanced angiography (CE-MRA) for stenosis measurement and compared to 2D T1-w TSE for intra-plaque hemorrhage (IPH) detection. METHODS: Eighty three patients underwent carotid MRI, using a new elliptic-centric phase encoding T1-weighted 3D TSE sequence in addition to the clinical protocol. Two observers evaluated image quality, presence of flow artifacts, and presence of intra-plaque hemorrhage, and computed the NASCET degree of stenosis for CE-MRA and for the new sequence...
June 16, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28629561/multi-contrast-and-three-dimensional-assessment-of-the-aortic-wall-using-3t-mri
#2
Thomas Wehrum, Iulius Dragonu, Christoph Strecker, Jürgen Hennig, Andreas Harloff
OBJECTIVES: To develop a 3D-multi-contrast MRI protocol allowing for high resolution imaging of the wall and of atheroma in the thoracic aorta. METHODS: Eleven healthy volunteers and eleven acute stroke patients with aortic plaques detected by TEE underwent MRI at 3T. The MRI-protocol consisted of a T1w-bright-blood, a T2w- and a PDw-black-blood sequence (spatial resolution=1.15mm(3)). Image quality was assessed by two blinded investigators using a 3-point score and intra- and inter-rater agreement was tested...
June 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28548886/association-of-preventive-maintenance-therapy-compliance-and-peri-implant-diseases-a-cross-sectional-study
#3
Alberto Monje, Hom-Lay Wang, José Nart
AIM: This study was aimed at investigating the association between peri-implant maintenance therapy (PIMT) and the frequency of peri-implant diseases, and to further identify the factors that contribute to failure of PIMT compliance. MATERIAL AND METHODS: A cross-sectional study on healthy partial edentulous patients was conducted. These were grouped in the following categories according to the PIMT compliance: regular compliers (RC) (≥2 PIMT/year), erratic compliers (EC) (<2 PIMT/year), and non-compliers (NC) (0 PIMT/year)...
May 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28540212/infarct-characterization-using-ct
#4
REVIEW
Ludovico La Grutta, Patrizia Toia, Erica Maffei, Filippo Cademartiri, Roberto Lagalla, Massimo Midiri
Myocardial infarction (MI) is a major cause of death and disability worldwide. The incidence is not expected to diminish, despite better prevention, diagnosis and treatment, because of the ageing population in industrialized countries and unhealthy lifestyles in developing countries. Nowadays it is highly requested an imaging tool able to evaluate MI and viability. Technology improvements determined an expansion of clinical indications from coronary plaque evaluation to functional applications (perfusion, ischemia and viability after MI) integrating additional phases and information in the mainstream examination...
April 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28536522/a-high-resolution-mri-study-of-relationship-between-remodeling-patterns-and-ischemic-stroke-in-patients-with-atherosclerotic-middle-cerebral-artery-stenosis
#5
Dan-Feng Zhang, Yu-Chen Chen, Huiyou Chen, Wei-Dong Zhang, Jun Sun, Cun-Nan Mao, Wen Su, Peng Wang, Xindao Yin
Purpose: Recently, high-resolution magnetic resonance imaging (HR-MRI) has been used to depict the wall characteristics of the intracranial arteries. The aim of this study was to explain the relationship between the remodeling patterns and acute ischemic stroke in patients with atherosclerotic middle cerebral artery (MCA) stenosis using HR-MRI. Materials and Methods: From August 2015 to May 2016, we prospectively screened 33 consecutive patients with unilateral MCA stenosis using time-to-flight MR angiography, including 15 patients with symptomatic MCA stenosis and 18 patients with asymptomatic MCA stenosis...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28514220/case-242-radiation-induced-angiosarcoma
#6
Meredith Disharoon, Kamilia F Kozlowski, Jessica M Kaniowski
History In 2004, this woman received a diagnosis of invasive mammillary carcinoma, tubular variant, strongly positive for estrogen and progesterone receptors. Her lesion was found at screening mammography performed at an outside institution when she was 59 years old. She underwent partial mastectomy, with partial axillary node dissection and sentinel node mapping. A 0.6 × 0.5 cm Nottingham grade 1 infiltrating ductal carcinoma was removed from the right upper outer quadrant, margins were free of tumor, and there was no angiolymphatic invasion...
June 2017: Radiology
https://www.readbyqxmd.com/read/28500539/hybrid-pet-ct-and-pet-mri-imaging-of-vulnerable-coronary-plaque-and-myocardial-scar-tissue-in-acute-myocardial-infarction
#7
Stephanie Marchesseau, Aruni Seneviratna, A Therese Sjöholm, Daphne Liang Qin, Jamie X M Ho, Derek J Hausenloy, David W Townsend, A Mark Richards, John J Totman, Mark Y Y Chan
BACKGROUND: Following an acute coronary syndrome, combined CT and PET with (18)F-NaF can identify coronary atherosclerotic plaques that have ruptured or eroded. However, the processes behind (18)F-NaF uptake in vulnerable plaques remain unclear. METHODS AND RESULTS: Ten patients with STEMI were scanned after (18)F-NaF injection, for 75 minutes in a Siemens PET/MR scanner using delayed enhancement (LGE). They were then scanned in a Siemens PET/CT scanner for 10 minutes...
May 12, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28473341/neuroradiologists-compared-with-non-neuroradiologists-in-the-detection-of-new-multiple-sclerosis-plaques
#8
W Wang, J van Heerden, M A Tacey, F Gaillard
BACKGROUND AND PURPOSE: Multiple sclerosis monitoring is based on the detection of new lesions on brain MR imaging. Outside of study populations, MS imaging studies are reported by radiologists with varying expertise. The aim of this study was to investigate the accuracy of MS reporting performed by neuroradiologists (someone who had spent at least 1 year in neuroradiology subspecialty training) versus non-neuroradiologists. MATERIALS AND METHODS: Patients with ≥2 MS studies with 3T MR imaging that included a volumetric T2 FLAIR sequence performed between 2009 and 2011 inclusive were recruited into this study...
May 4, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28470406/targeting-mannose-receptor-expression-on-macrophages-in-atherosclerotic-plaques-of-apolipoprotein-e-knockout-mice-using-111-in-tilmanocept
#9
Zohreh Varasteh, Fabien Hyafil, Nadège Anizan, Devy Diallo, Rachida Aid-Launais, Sarajo Mohanta, Yuanfang Li, Miriam Braeuer, Katja Steiger, Jonathan Vigne, Zhengtao Qin, Stephan G Nekolla, Jean-Etienne Fabre, Yvonne Döring, Dominique Le Guludec, Andreas Habenicht, David R Vera, Markus Schwaiger
BACKGROUND: Atherosclerotic plaque phenotypes are classified based on the extent of macrophage infiltration into the lesions, and the presence of certain macrophage subsets might be a sign for plaque vulnerability. The mannose receptor (MR) is over-expressed in activated macrophages. Tilmanocept is a tracer that targets MR and is approved in Europe and the USA for the detection of sentinel lymph nodes. In this study, our aim was to evaluate the potential of (111)In-labelled tilmanocept for the detection of MR-positive macrophages in atherosclerotic plaques of apolipoprotein E-knockout (ApoE-KO) mouse model...
December 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28438779/human-alternative-macrophages-populate-calcified-areas-of-atherosclerotic-lesions-and-display-impaired-rankl-induced-osteoclastic-bone-resorption-activity
#10
Giulia Chinetti-Gbaguidi, Mehdi Daoudi, Mickael Rosa, Manjula Vinod, Loïc Louvet, Corinne Copin, Melanie Fanchon, Jonathan Vanhoutte, Bruno Derudas, Loic Belloy, Stephan Haulon, Christophe Zawadzki, Sophie Susen, Ziad A Massy, Jérôme Eeckhoute, Bart Staels
Rationale: Vascular calcification is a process similar to bone formation leading to an inappropriate deposition of calcium phosphate minerals in advanced atherosclerotic plaques. Monocyte-derived macrophages, located in atherosclerotic lesions and presenting heterogeneous phenotypes, from classical pro-inflammatory M1 to alternative anti-inflammatory M2 macrophages, could potentially display osteoclast-like functions. Objective: To characterize the phenotype of macrophages located in areas surrounding the calcium deposits in human atherosclerotic plaques...
April 24, 2017: Circulation Research
https://www.readbyqxmd.com/read/28432519/carotid-plaque-with-expansive-arterial-remodeling-is-a-risk-factor-for-ischemic-complication-following-carotid-artery-stenting
#11
Daina Kashiwazaki, Naoya Kuwayama, Naoki Akioka, Kyo Noguchi, Satoshi Kuroda
BACKGROUND: Carotid artery stenting (CAS) is associated with a higher risk of periprocedural stroke than carotid endarterectomy. For better patient selection, more accurate risk factors should be identified. The aim of this study was to determine whether expansive arterial remodeling can predict ischemic complications in patients undergoing CAS. METHODS: This retrospective study included 82 patients with carotid stenosis treated by CAS. The plaque component was evaluated using MR plaque imaging before the procedure...
July 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28412421/change-in-carotid-plaque-components-a-4-year-follow-up-study-with-serial-mr-imaging
#12
Laura Pletsch-Borba, Mariana Selwaness, Aad van der Lugt, Albert Hofman, Oscar H Franco, Meike W Vernooij
OBJECTIVES: The goal of this study was to determine how carotid plaque components (e.g., intraplaque hemorrhage [IPH], calcification, lipid core) change over time and which cardiovascular risk factors are associated with the development of each component. BACKGROUND: Carotid atherosclerotic plaque components are important markers of plaque vulnerability. How these components change and which factors lead to the development and changes in the components remain unclear...
April 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28386716/importance-of-variants-in-cerebrovascular-anatomy-for-potential-retrograde-embolization-in-cryptogenic-stroke
#13
Michael Markl, Edouard Semaan, LeRoy Stromberg, James Carr, Shyam Prabhakaran, Jeremy Collins
OBJECTIVES: To test the hypothesis that variants in cerebrovascular anatomy will affect the number of patients demonstrating a plausible retrograde embolization mechanism from plaques in the descending aorta (DAo). METHODS: Thirty-five patients (aged 63 ± 17 years) with cryptogenic stroke underwent 4D flow MRI for the assessment of aortic 3D blood flow and MR angiography for the evaluation of circle of Willis, posterior circulation, and aortic arch architecture...
April 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28386172/angiotensin-ii-accelerated-vulnerability-of-carotid-plaque-in-a-cholesterol-fed-rabbit-model-assessed-with-magnetic-resonance-imaging-comparing-to-histopathology
#14
Beibei Sun, Huilin Zhao, Xiao Li, Hong Yao, Xiaosheng Liu, Qing Lu, Jieqing Wan, Jianrong Xu
This study sought to reveal the effect of angiotensin II (Ang II)-induced atherosclerotic vulnerability in rabbits and to determine whether in vivo magnetic resonance imaging (MRI) can determine the effect of Ang II on atherosclerotic development over time. In total, 24 elderly male New Zealand white rabbits underwent an intravascular balloon injury in the left common carotid artery (LCCA) and were subsequently fed a high cholesterol diet for 12 weeks. At 8 weeks, rabbits were randomly assigned to receive either Ang II (1...
March 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28321471/feasibility-of-in-vivo-18-f-florbetaben-pet-mr-imaging-of-human-carotid-amyloid-%C3%AE
#15
Jan Bucerius, Henryk Barthel, Solveig Tiepolt, Peter Werner, Judith C Sluimer, Joachim E Wildberger, Marianne Patt, Swen Hesse, Hermann-Josef Gertz, Erik A L Biessen, Felix M Mottaghy, Osama Sabri
PURPOSE: Amyloid-beta (Aβ) peptides are involved in the inflammatory pathology of atherosclerosis. (18)F-Florbetaben is a PET tracer for clinical imaging of cerebral Aβ plaques in Alzheimer's disease (AD). We sought to determine whether specific uptake of (18)F-florbetaben in the carotid arteries can be identified using a fully integrated hybrid PET/MRI system and whether this uptake is associated with clinical cardiovascular disease (CVD) risk factors. METHODS: Carotid (18)F-florbetaben uptake was quantified as the mean of the maximum target-to-background ratio (meanTBRmax) in 40 cognitively impaired subjects (age 68...
July 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28275562/a-comprehensive-literatures-update-of-clinical-researches-of-superparamagnetic-resonance-iron-oxide-nanoparticles-for-magnetic-resonance-imaging
#16
REVIEW
Yì Xiáng J Wáng, Jean-Marc Idée
This paper aims to update the clinical researches using superparamagnetic iron oxide (SPIO) nanoparticles as magnetic resonance imaging (MRI) contrast agent published during the past five years. PubMed database was used for literature search, and the search terms were (SPIO OR superparamagnetic iron oxide OR Resovist OR Ferumoxytol OR Ferumoxtran-10) AND (MRI OR magnetic resonance imaging). The literature search results show clinical research on SPIO remains robust, particularly fuelled by the approval of ferumoxytol for intravenously administration...
February 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28256903/mr-imaging-in-patients-with-male-to-female-sex-reassignment-surgery-postoperative-anatomy-and-complications
#17
Michele Bertolotto, Giovanni Liguori, Stefano Bucci, Mariano Iannelli, Francesca Vedovo, Nicola Pavan, Carlo Trombetta, Lorenzo E Derchi
OBJECTIVE: To investigate the role of MRI in the evaluation of both the new female anatomy and complications in male-to-female sex reassignment surgery (MtF-SRS). METHODS: 71 consecutive patients with MtF-SRS had 74 MRI [age range, 21-63 years; mean (±standard deviation) age, 36 ± 10 years; median age, 37 years]. In 47 patients, MRI was performed to rule out early post-operative complications after gender conversion (n = 40), vaginoplasty (n = 6) or remodelling of the labia majora (n = 1)...
April 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28252427/renal-function-markers-for-long-term-cardiovascular-prediction-in-individuals-after-myocardial-revascularization
#18
E Levitskaya
Goal - assessment of the renal dysfunction impact on the probability of cardiovascular complications development in the long-term period after myocardial revascularization. 90 patients with ischemic heart disease (IHD) and myocardial revascularization indications were involved in the study. All the patients underwent coronary angiography (CAG), by determining the method of myocardial revascularization (MR) - coronary artery bypass grafting or coronary artery stenting. Traditional risk factors and renal dysfunction markers (albuminuria in the range of 30-300 mg/L, β2-microglobulinuria) were revealed in all the patients examined...
January 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28245785/vascular-consequences-of-aldosterone-excess-and-mineralocorticoid-receptor-antagonism
#19
Sophocles Chrissobolis
Aldosterone binds to mineralocorticoid receptors (MRs) on renal epithelial cells to regulate sodium and water reabsorption, and therefore blood pressure. Recently, the actions of aldosterone outside the kidney have been extensively investigated, with numerous reports of aldosterone having detrimental actions, including in the vasculature. Notably, elevated aldosterone levels are an independent cardiovascular risk factor, and in addition to causing an increase in blood pressure, aldosterone can have blood pressure-dependent and -independent effects commonly manifested in the vasculature in cardiovascular diseases, including vascular oxidative stress, endothelial dysfunction, inflammation, remodeling, stiffening, and plaque formation...
February 28, 2017: Current Hypertension Reviews
https://www.readbyqxmd.com/read/28216518/optimization-of-t1-weighted-imaging-parameters-in-mr-carotid-plaque-imaging-influence-for-the-quantitative-evaluation-among-different-mri-scanner-types
#20
Takanori Naka, Mitsuyuki Takahashi, Koutarou Takeda, Tarou Igarashi, Tetsukazu Hondera
Carotid artery plaques with high-signal intensity on T1 weighted image (T1 WI) are known to cause cerebral ischemic disease. Signal intensity ratio (SIR), which is calculated from T1 WI in the quantitative evaluation of plaque characterization have been used. However, the various sequences in T1 WI and difference in the sequences were utilized among institutions. Therefore, difference in sequence may influence SIR. The purpose of this study was to evaluate the optimization of T1 WI sequence in MR carotid plaque imaging...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
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