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Yong-Yon Won, Dong-Woo Suh, Bark-Lynn Lew, Woo-Young Sim
Syringoid eccrine carcinoma (SEC) is a rare cutaneous malignant tumor thought to be derived from eccrine sweat apparatus. It is usually present in the head, neck and trunk region, and often occurs in the fourth to seventh decades of life. A 94-year-old male patient visited our department with an 80-year history of a lesion showing a 2×2 cm sized well-demarcated round shaped erythematous to pinkish colored nodule with ulcer on his left thigh. Histological findings revealed a tumor consisted mainly of numerous small cords and nests forming luminal or tubular structures and tumor cells showing variable atypia...
December 2017: Annals of Dermatology
Woo Cheal Cho, Brian Wagner, Melissa Gulosh, Zendee Elaba
Syringoid eccrine carcinoma is a rare malignant adnexal tumor that typically presents in the head and neck region. Involvement of the extremities is uncommon, with only a few cases reported in the literature. Here, we report our experience with a rare case of syringoid eccrine carcinoma occurring on the plantar surface of the right foot in a 47-year-old African American woman. Histologically, incisional biopsy revealed a tumor consisting of tubulocystic structures lined by basaloid cells with an infiltrative growth pattern, extending from the reticular dermis to the deep biopsy margin...
May 1, 2017: International Journal of Surgical Pathology
Syed Morteza Abedi, Ryan Yu, Samih Salama, Salem Alowami
No abstract text is available yet for this article.
September 2015: Cutis; Cutaneous Medicine for the Practitioner
Manjool M Shah, Eric A Steele, Kevin P White, David J Wilson
No abstract text is available yet for this article.
2014: International Journal of Ophthalmology
John F Grady, Yelena Boumendjel, Maliha S Tahniyath
Syringoid eccrine carcinoma is a very rare skin cancer. We present a case of a 22-year-old woman with a presentation of syringoid eccrine carcinoma in the subungual region of the hallux. This clinical case demonstrates our work-up that led to a proper diagnosis and management of this pathology. We discuss our surgical procedure of choice and the outcome. This report adds valuable information to a limited database of knowledge available on the diagnosis and management of syringoid eccrine carcinomas.
September 2014: Journal of the American Podiatric Medical Association
Elisa Piovano, Annamaria Ferrero, Nicoletta Ravarino, F Martra, Paola Modaffari, Paolo Zola
► Syringoid eccrine carcinoma (SEC) is a rare tumor. ► There are no published reports describing diagnosis of this tumor on the vulva. ► We report a case of a 58-year-old female with a SEC of left labia majora.
2011: Gynecologic Oncology Case Reports
Pierluigi Ballardini, Guido Margutti, Massimo Pedriali, Patrizia Querzoli
Syringoid eccrine carcinoma is a very rare skin tumor. Herein we describe a 72-year-old male patient presenting with a syringoid eccrine carcinoma of the nipple with associated axillary lymph node metastases. Surgery associated with adjuvant radiotherapy was performed. To the best of our knowledge, this is the first case of syringoid eccrine carcinoma of the nipple ever reported.
2012: International Medical Case Reports Journal
Prachi G Agrawal, Sunanda A Mahajan, Uday S Khopkar, Vidya D Kharkar
Epidermodysplasia verruciformis (EV) is a rare, life-long heritable disease caused due to a unique susceptibility to human papilloma virus. The disseminated verrucous lesions and pityriasis versicolor-like lesions persist from early childhood and can transform into a cutaneous malignancy in a fourth of patients. Malignant transformation into syringoid eccrine carcinoma (SEC) has been reported only once so far. SEC is an extremely invasive, rare, locally destructive, slowly growing adnexal tumor. We hereby report the association of EV with SEC in a 29-year-old male...
January 2013: Indian Journal of Dermatology, Venereology and Leprology
M Sidiropoulos, S Sade, A Al-Habeeb, D Ghazarian
BACKGROUND: Syringoid eccrine carcinoma (SEC) is a rare malignant adnexal tumour with variable presentations. AIM: To examine the clinicopathological and immunohistochemical features of SEC. METHODS: Four cases were reviewed by three dermatopathologists and the immunohistochemical profile was examined using antibodies against CK5/6, CK7, CK14, CK20, LMWK, HMWK, EMA, mCEA, p63, ER, PR, AR, S-100 and Ber-EP4. RESULTS: The cases occurred in two men and two women, ranging in age from 61 to 87 years (mean 68...
September 2011: Journal of Clinical Pathology
Chuieng-Yi Lu, Shih-Ming Jung, Yu-Te Lin
We present a case of sclerosing syringoid carcinoma of the finger, a type of eccrine sweat duct malignancy that is rare and mimics the appearance of a benign lesion, but is locally aggressive and has a tendency to recur. It has seldom been reported in the literature. It has a predilection for the head and neck region but is rare in the extremities. We believe this is the second reported case of sclerosing syringoid carcinoma in the finger, after the diagnosis was determined from a histological and immunohistochemical study...
January 2011: Chang Gung Medical Journal
Mohamed Khalifa Ahmed, Takashi Ishino, Katsuhiro Hirakawa, Koji Arihiro
First described in 1969, syringoid eccrine carcinoma (SEC) is a rare cutaneous tumor with some controversy regarding its correct definition. It consists of solid nests and small cords in a dense fibrocollagenous stroma. As it is rare, its clinical appearance is not well characterized and its biological behaviour is not defined. It usually affects skin of the scalp, extremities and more rarely, other sites. It behaves as locally aggressive tumor but metastases are rare. Although there have been some previous reports describing clinical presentation and management of SEC in the skin, there has been no previous reports describing clinical findings and management of this tumor in the external auditory canal...
August 2010: Auris, Nasus, Larynx
Jorge O Güerrissi, Juan Pablo Quiroga
Adnexal carcinomas of the skin are rare and they derive from structures such as sweat glands, sebaceous glands, and hair follicles. Adnexal tumors represent 1-2% of skin cancers. Between 1998 and 2004, eight patients with malignant adnexal tumors of the head and neck were treated in the Plastic Surgery Service in Argerich Hospital in Buenos Aires, Argentina. Four (50%) of them had malignant cylindromas, two (25%) had sebaceous carcinoma, and the other two (25%) syringoid eccrine carcinoma. Tumor resection and local flaps were made in all cases...
July 2008: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
Umberto Goglia, Carlo Toncini, Massimo Giusti, Christian Gastaldi, Carlo Ambruosi, Simona Sola, Jean-Louis Ravetti, Giorgio Carmignani, Francesco Minuto, Diego Ferone
No abstract text is available yet for this article.
January 2008: Journal of Andrology
Aya Nishizawa, Yukihiro Nakanishi, Yuko Sasajima, Naoya Yamazaki, Akifumi Yamamoto
No abstract text is available yet for this article.
October 2006: International Journal of Dermatology
Y Minami, K Uede, K Sagawa, A Kimura, T Tsuji, F Furukawa
BACKGROUND: Recently, the novel antimicrobial peptide named dermcidin (DCD) was reported in human eccrine sweat glands. OBJECTIVES: We investigated the expression of DCD in a variety of cutaneous tumours in order to assess the usefulness of the monoclonal antibody (G-81), which recognizes a fragment of DCD. PATIENTS/METHODS: We studied the immunoreactivity of the G-81 antibody on 197 cutaneous tumours. RESULTS: A total of 13 of 26 cutaneous mixed tumours showed substantial immunoreactivity...
July 2004: British Journal of Dermatology
Takamitsu Ohnishi, Sakae Kaneko, Motoko Egi, Hajime Takizawa, Shinichi Watanabe
Syringoid eccrine carcinoma is an extremely rare cutaneous malignant tumor, thought to be derived from eccrine sweat apparatus. We report a case of syringoid eccrine carcinoma occurring on the scalp of a 66-year-old woman and analyzed its cytokeratin expression immunohistochemically to clarify its histogenesis. The tumor consisted mainly of numerous small cords and nests extending from the reticular dermis to the subcutaneous tissue, which formed luminal or tubular structures mimicking the nests of syringoma...
October 2002: American Journal of Dermatopathology
T Gregurek-Novak, J Talan-Hranilović, N Troskot, M Vucić, B Kruslin
A rare case of a syringoid eccrine carcinoma in a 52-year-old male patient is described. During the first hospitalization, syringoma was diagnosed, both clinically and histologically, keeping in mind the possibility of its malignant alteration. Difficulties in making a diagnosis with histological and immunohistochemical examinations are reported. The possibility of differential diagnosis of primary breast carcinoma and methods of its exclusion are also described. Treatment of the patient was surgical with good results...
March 2001: Journal of the European Academy of Dermatology and Venereology: JEADV
C M Stefanato, D A Simkin, J Bhawan
The intimate association of nevomelanocytic nevi with eccrine ducts commonly seen in congenital nevi was emphasized by Mishima, who described as eccrine-centered nevi those lesions characterized by nevomelanocytic cells predominantly proliferating around and within the eccrine sweat duct walls. However, there were no changes in the overlying epidermis, dermis, or eccrine acrosyringeal or dermal duct proliferation in these lesions. We present the case of a 16-year-old boy with a 1-year-history of a 0.6-cm diameter single tan papule on the right heel, clinically thought to be a Spitz nevus...
April 2001: American Journal of Dermatopathology
D Ramos, C Monteagudo, C Carda, E Montesinos, J Ferrer, A Peydro-Olaya
Syringoid carcinoma (syringoid "eccrine" carcinoma or eccrine epithelioma) is a rare cutaneous tumor with some controversy regarding its correct definition. It may also be difficult to differentiate from its benign counterpart (syringoma), other adnexal carcinomas, and cutaneous metastasis from adenocarcinomas. We present a case of a syringoid carcinoma of the clear cell variant complemented with an immunohistochemical and ultrastructural study, the latter revealing cytoplasmic accumulation of glycogen and presence of intercellular and intracellular lumina in clear tumor cells, as well as diverse hallmarks of malignancy (i...
February 2000: American Journal of Dermatopathology
G Ferrara, O Nappi, M R Wick
Low-grade adenosquamous carcinoma of the breast (LASCB) is a relatively recently-described, rare histotype of breast cancer that has a favorable prognosis. Its principal microscopic features are the presence of "syringoid" ("tadpole"-shaped) ductal profiles of tumor cells, a bland and modestly cellular stromal background, and the variable presence of keratinizing ("epidermoid") cell groups. As such, the basic image of LASCB is quite similar to that of microcystic adnexal or adenosquamous carcinoma of the skin or "syringomatous adenoma" of the nipple...
January 1999: Diagnostic Cytopathology
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