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https://www.readbyqxmd.com/read/29766130/resuscitative-endovascular-balloon-occlusion-of-the-aorta-rupture-risk-and-implications-for-blind-inflation
#1
Philip J Wasicek, William A Teeter, Megan L Brenner, Melanie R Hoehn, Thomas M Scalea, Jonathan J Morrison
Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a torso hemorrhage control technique. To expedite deployment, inflation is frequently performed as a blind technique with minimal imaging, which carries a theoretical risk of aortic injury. The objective of this study was to examine the relationship between balloon inflation, deformation and the risk of aortic rupture. Methods: Compliant balloon catheters were incrementally inflated in segments of cadaveric swine aorta...
2018: Trauma surgery & acute care open
https://www.readbyqxmd.com/read/29763925/the-influence-of-hyperlipidemia-on-endothelial-function-of-fpn1-tek-cre-mice-and-the-intervention-effect-of-tetramethylpyrazine
#2
Ming-Yue Sun, Miao Zhang, Shui-Ling Chen, Shu-Ping Zhang, Chun-Yu Guo, Jing-Shang Wang, Xin Liu, Yang Miao, Hui-Jun Yin
BACKGROUND/AIMS: Systemic iron homeostasis is strictly governed in mammals; however, disordered iron metabolism (such as excess iron burden) is recognized as a risk factor for various types of diseases including AS (Atherosclerosis). The hepcidin-ferroportin axis plays the key role in regulation of iron homeostasis and modulation of this signaling could be a potential therapeutic strategy in the treatment of these diseases. TMP (Tetramethylpyrazine) has been reported to have therapeutical effect on AS...
May 9, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29753817/arch-augmentation-via-median-sternotomy-for-coarctation-of-aorta-with-proximal-arch-hypoplasia
#3
W Hampton Gray, Winfield J Wells, Vaughn A Starnes, S Ram Kumar
BACKGROUND: Coarctation of the aorta can be associated with hypoplasia of the proximal transverse aortic arch. One approach to manage this condition is via left thoracotomy and extended end-to-end anastomosis with the expectation that the proximal arch will grow over time. Our preferred approach is to augment the aorta via midline sternotomy. We hypothesized that this approach is safe, durable and allows reliable growth of the aorta. METHODS: We identified the records of patients with biventricular anatomy who had coarctation of the aorta, hypoplasia of the proximal transverse arch, and no other cardiac lesion that would mandate cardiopulmonary bypass use and midline sternotomy...
May 10, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29751180/radiographic-study-of-lumbar-sympathetic-trunk-in-the-oblique-lateral-interbody-fusion-surgery
#4
Hongli Wang, Yuxuan Zhang, Xiaosheng Ma, Xinlei Xia, Feizhou Lu, Jianyuan Jiang
BACKGROUND: Oblique lateral interbody fusion (OLIF) surgery provides a convenient and minimal access to the lesion disc with few complications, however, the left lumbar sympathetic trunk (LST) lies in the surgical field with an certain incidence of injury. The aim of this study was to describe the anatomical structures of the left LST at risk for injury during oblique lateral interbody fusion at different lumbar segment levels based on radiological evaluations. METHODS: 44 healthy young people (22 males and 22 females) were recruited and routine lumbar MR radiograph were performed...
May 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29750927/frozen-elephant-trunk-for-acute-type-b-dissection-involving-the-distal-arch-in-the-hybrid-repair-era
#5
Rui-Dong Qi, Jun-Ming Zhu, Yong-Min Liu, Lei Chen, Cheng-Nan Li, Xiao-Yan Xing, Nan Zhang, Li-Zhong Sun
BACKGROUND: Hybrid repair of complicated acute type B aortic dissection(ATBAD) with aortic arch involvement is associated with a high rate of endoleak, stroke, and retrograde aortic dissection. Optimal management of this lesion remains uncertain. In this hybrid repair era, surgical results of ATBAD with distal aortic arch involvement using a frozen elephant trunk(FET) procedure with left subclavian artery(LSCA)-left common carotid artery(LCCA) transposition is reported. METHODS: From April 2011 to April 2016, 53 patients with complicated ATBAD with distal aortic arch involvement underwent a FET procedure with LSCA-LCCA transposition...
May 8, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29749315/irisin-in-coronary-bypass-surgery
#6
Suna Aydin, Zekiye Catak, Mehmet Nesimi Eren, Suleyman Aydin, Askin Ender Topal
INTRODUCTION: In coronary bypass surgery, after cardiopulmonary bypass is initiated by arterial cannulation in the ascending aorta and venous cannulation through a single vein generally in the right atrium, the process of cooling the patient is started. There is a relation between cooling the patient and irisin, which is responsible for releasing heat. OBJECTIVE: Therefore, the main objective of the present study is to explore how irisin concentrations and some other panel of myocardium injury in patients undergoing coronary artery bypass surgery changes...
May 11, 2018: Cardiovascular & Hematological Disorders Drug Targets
https://www.readbyqxmd.com/read/29748101/results-from-the-study-to-assess-outcomes-after-endovascular-repair-for-multiple-thoracic-aortic-diseases-summit
#7
Nikolaos Tsilimparis, Sebastian Debus, Min Chen, Qing Zhou, Mary-Margaret Seale, Tilo Kölbel
OBJECTIVE: Thoracic endovascular aortic repair (TEVAR) is currently the treatment of choice for most diseases of the descending thoracic aorta. Using data from the Study to Assess Outcomes After Endovascular Repair for Multiple Thoracic Aortic Diseases (SUMMIT) study we investigated the outcomes of TEVAR for different aortic diseases and risk factors associated with the outcomes. METHODS: The SUMMIT study included aggregated data of 521 TEVAR patients from five Cook-sponsored multicenter trials evaluating thoracic endografts of the Zenith platform (William Cook Europe, ApS, Bjaeverskov, Denmark)...
May 7, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29739656/hip-dislocations-and-concurrent-injuries-in-motor-vehicle-collisions
#8
Joseph Cooper, Justin Tilan, Alexis D Rounds, Santano Rosario, Kenji Inaba, Geoffrey S Marecek
INTRODUCTION: Motor Vehicle Collisions (MVC) can cause high energy hip dislocations associated with serious injury profiles impacting triage. Changes in safety and regulation of restraint devices have likely lowered serious injuries from what was previously reported in the 1990s. This study aims to describe modern-day injury profile of patients with traumatic hip dislocations, with special attention to aortic injury. METHODS: Retrospective review of a prospectively maintained trauma database at an urban level 1 trauma center was conducted...
April 27, 2018: Injury
https://www.readbyqxmd.com/read/29737475/effect-of-a-stellate-ganglion-block-on-acute-lung-injury-in-septic-rats
#9
Yong Chen, Lian Guo, Haili Lang, Xiaolan Hu, Sun Jing, Mengsi Luo, Guohai Xu, Zhidong Zhou
A stellate ganglion block (SGB) is a clinical sympathetic block which can inhibit the body systemic inflammatory response. However, whether and how SGB can attenuate the sepsis-induced acute lung injury remains unclear. Here, we evaluated the effect of SGB on sepsis-induced acute lung injury in rats. Ninety healthy Sprague Dawley (SD) male rats were divided into three groups: the sham operation group (S group), sepsis group (Sep group), and SGB group. The sepsis model rats were produced by cecum ligation and puncture (CLP), and blood samples were taken from the abdominal aorta of the rats at different time points for evaluating the concentration of TNF-α, IL-6, and IL-10 by enzyme-linked immunosorbent assay (ELISA)...
May 8, 2018: Inflammation
https://www.readbyqxmd.com/read/29725558/aortic-rupture-during-surgical-management-of-tubercular-spondylodiscitis
#10
Phani Krishna Karthik Yelamarthy, Rajat Mahajan, Tarush Rustagi, Vikas Tandon, Gururaj Sangondimath, Harvinder Singh Chhabra
Aortic rupture is a rare but possible complication during spine surgery. It may manifest as severe intraoperative hemorrhage or present in a delayed manner after the formation of an aneurysm or an arteriovenous fistula. Though it is commonly encountered during anterior surgeries involving the surgical field close to the thoracic or abdominal aorta, it can also occur during a posterior surgery. Aortic injury could be associated with surgeries ranging from the commonly performed pedicle screw instrumentation to a complex three-column osteotomy...
March 1, 2018: Curēus
https://www.readbyqxmd.com/read/29724533/targeting-phosphodiesterase-5-by-vardenafil-improves-vascular-graft-function
#11
Gábor Veres, Martin Hagenhoff, Harald Schmidt, Tamás Radovits, Sivakkanan Loganathan, Yang Bai, Sevil Korkmaz-Icöz, Paige Brlecic, Alex Ali Sayour, Matthias Karck, Gábor Szabó
OBJECTIVES: Ischaemia reperfusion (IR) injury occurs during vascular graft harvesting and implantation during vascular/cardiac surgery. Elevated intracellular cyclic guanosine monophosphate (cGMP) levels contribute to an effective endothelial protection in different pathophysiological conditions. The hypothesis that the phosphodiesterase-5 inhibitor vardenafil would protect vascular grafts against IR injury by upregulating the nitric oxide-cGMP pathway in the vessel wall of the bypass graft was investigated...
May 1, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29709584/resuscitative-endovascular-balloon-occlusion-of-the-aorta-implementation-and-preliminary-results-at-an-academic-level-i-trauma-center
#12
Marcus D Darrabie, Chasen A Croft, Scott C Brakenridge, Alicia M Mohr, Martin A Rosenthal, Frederick A Moore, R Stephen Smith
BACKGROUND: REBOA is a novel method of controlling subdiaphragmatic hemorrhage while improving hemodynamic stability. This procedure achieves many of the goals of resuscitative thoracotomy (RT), but is less invasive. Herein, we present the initial experience with REBOA at a level 1 academic trauma center. STUDY DESIGN: A retrospective review was performed. Orientation of surgeons and residents to REBOA was accomplished by an educational program including a hands-on simulation session (1...
April 11, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29708335/inhibitive-effects-of-quercetin-on-myeloperoxidase-dependent-hypochlorous-acid-formation-and-vascular-endothelial-injury
#13
Naihao Lu, Yinhua Sui, Rong Tian, Yiyuan Peng
Myeloperoxidase (MPO) from activated neutrophils plays important roles in multiple human inflammatory diseases by catalyzing the formation of powerful oxidant hypochlorous acid (HOCl). As a major flavonoid in the human diet, quercetin has been suggested to act as antioxidant and anti-inflammatory agent in vitro and in vivo. In this study, we showed that quercetin inhibited MPO-mediated HOCl formation (75.0±6.2% for 10 μM quercetin versus 100±5.2% for control group, P<0.01) and cytotoxicity to endothelial cells in vitro, while this flavonoid was nontoxic to endothelial cell cultures (P > 0...
April 30, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29707550/complications-on-minimally-invasive-oblique-lumbar-interbody-fusion-at-l2-l5-levels-a-review-of-the-literature-and-surgical-strategies
#14
REVIEW
Javier Quillo-Olvera, Guang-Xun Lin, Hyun-Jin Jo, Jin-Sung Kim
Fusion is the cornerstone in the treatment of an unstable degenerative lumbar spinal disease. Various techniques have been developed. Amongst these techniques exists the oblique lumbar interbody fusion (OLIF), which is the ante-psoas approach. Adequate restoration of disc height with large cages placed in the intervertebral space, indirect decompression, and correction of sagittal and coronal alignment can be achieved with OLIF procedure with the advantage of minimal risk for the psoas muscle and lumbar plexus...
March 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29705775/the-effect-of-age-and-body-mass-index-on-the-surgical-anatomy-of-supraumbilical-port-insertion-implications-for-laparoscopic-and-robotic-surgery
#15
Mohamed A Bedaiwy, Paul J Yong, Tarek A Farghaly, Faten F Abdelhafez, Justin Tan, Rachel Pope, William W Hurd, James H Liu, Kristine Zanotti
BACKGROUND: Minimally invasive surgery is the preferred approach for performing many gynecologic procedures. Occasionally, supraumbilical port placement may be preferable to optimize visibility and maneuverability although the risks of complications are less well characterized compared to umbilical entry. METHODS: We conducted a retrospective review of computed tomograms from 92 patients to evaluate the anatomic considerations for umbilical and supraumbilical port entry based on patient age, body mass index (BMI), parity, abdominal wall thickness, and distance to the great vessels...
April 27, 2018: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/29705370/clinical-outcomes-of-vasoring-connector-in-patients-with-acute-type-a-aortic-dissection
#16
I-Ming Chen, Po-Lin Chen, Shih-Hsien Weng, Chiao-Po Hsu, Chun-Che Shih, Hsiao-Huang Chang, Jeng Wei
BACKGROUND: Outcomes of acute type A aortic dissection (TAAD) repair may be improved when VasoRing connectors (VRC) are employed to facilitate aortic anastomosis. In the present study, we compared the results of acute TAAD repair using VRC and conventional suture technique. METHODS: A total of 68 patients who underwent acute TAAD repair by total arch replacement and antegrade frozen elephant trunk procedure at our institution were enrolled. Records of patients receiving aorta anastomosis with VRC (n = 33) and conventional suture (n =35) were retrospectively compared...
April 26, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29699730/defining-degree-of-aortic-occlusion-for-partial-reboa-a-computed-tomography-study-on-large-animals
#17
Viktor A Reva, Yosuke Matsumura, Igor M Samokhvalov, Alexander A Pochtarnik, Igor S Zheleznyak, Ekaterina M Mikhailovskaya, Jonathan J Morrison
INTRODUCTION: Partial resuscitative endovascular balloon occlusion of the aorta (P-REBOA) is a modified REBOA technique designed to help ameliorate ischemia-reperfusion injury. The balloon is partially deflated, allowing a proportion of aortic flow distal to the balloon. The aim of this study is to use an ovine model of haemorrhagic shock to correlate the degree of occlusion to several hemodynamic indices. MATERIALS AND METHODS: Six sheep weighing 35-46 kg underwent a controlled venous haemorrhage inside a CT scanner until the systolic arterial pressure (AP) dropped to <90 mmHg...
April 20, 2018: Injury
https://www.readbyqxmd.com/read/29697519/intraoperative-combination-of-resuscitative-endovascular-balloon-occlusion-of-the-aorta-and-a-median-sternotomy-in-hemodynamically-unstable-patients-with-penetrating-chest-trauma-is-this-feasible
#18
Carlos A Ordoñez, Michael W Parra, Ramiro Manzano-Nunez, Juan P Herrera-Escobar, Jose J Serna, Paola Rodriguez Ossa, David Mejia, Ana M Del Valle, Alexander Salcedo, Juan C Salamea, Fernando Rodriguez
BACKGROUND: Recent evidence suggests that resuscitative endovascular balloon occlusion of the aorta (REBOA) is an effective life-saving intervention in patients with severe torso trauma. However, the deployment of REBOA in patients with isolated penetrating intrathoracic injuries remains controversial. We propose that a median sternotomy be performed in conjunction with REBOA as a feasible and effective means of hemorrhage control in patients suffering from penetrating chest trauma who present hemodynamically unstable...
May 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29685515/cerebral-embolization-during-endovascular-infrarenal-juxtarenal-and-suprarenal-aortic-aneurysm-repair-high-risk-maneuvers-and-associated-neurologic-outcomes
#19
Ruth A Benson, David Matthews, Vanessa Loftus, Grainne Nicholson, David Tropman, Ian M Loftus
BACKGROUND: Risk factors for postoperative cognitive decline after noncardiac surgery are multifactorial and poorly understood. Evidence suggests that perioperative microembolic damage to the brain on movement of wires and catheters during endovascular aortic procedures may play an important role. Endovascular aortic aneurysm repair requires invasive manipulation of wires and cannulas within the aorta, but research into cerebral emboli during aortic aneurysm repair and cognitive or neurologic injury is scarce and limited to thoracic aneurysms...
April 20, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29685373/resuscitative-endovascular-balloon-occlusion-of-the-aorta-improves-cardiac-compression-fraction-versus-resuscitative-thoracotomy-in-patients-in-traumatic-arrest
#20
William Teeter, Anna Romagnoli, Philip Wasicek, Peter Hu, Shiming Yang, Deborah Stein, Thomas Scalea, Megan Brenner
STUDY OBJECTIVE: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is emerging as an alternative to resuscitative thoracotomy for proximal aortic control in select patients with exsanguinating hemorrhage below the diaphragm. The purpose of this study is to compare interruptions in closed chest compression or open chest cardiac massage during REBOA versus resuscitative thoracotomy. METHODS: From May 2014 to December 2016, patients in arrest who received aortic occlusion with REBOA or resuscitative thoracotomy were included...
April 20, 2018: Annals of Emergency Medicine
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