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https://www.readbyqxmd.com/read/28340450/health-promotion-and-psychological-interventions-for-adolescent-and-young-adult-cancer-survivors-a-systematic-literature-review
#1
REVIEW
Natalie Katrina Bradford, Raymond Javan Chan
BACKGROUND: The effects of cancer and treatment have severe and long lasting negative impacts on quality of life. Adolescents and Young Adults (AYA) have high survival rates but may not reach their full life potential because of these consequences. This review aims to identify, appraise and synthesise the effects of health promotion and psychological interventions for AYA after cancer treatment. METHODS: The review was undertaken using the preferred reporting items for systematic reviews and meta-analyses guidelines...
March 6, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28339812/spending-on-hospital-care-and-pediatric-psychology-service-use-among-adolescents-and-young-adults-with-cancer
#2
Meghan E McGrady, James L Peugh, Gabriella A Brown, Ahna L H Pai
To examine the relationship between need-based pediatric psychology service use and spending on hospital care among adolescents and young adults (AYAs) with cancer. Billing data were obtained from 48 AYAs with cancer receiving need-based pediatric psychology services and a comparison cohort of 48 AYAs with cancer not receiving services. A factorial analysis of covariance examined group differences in spending for hospital care. Pending significant findings, a multivariate analysis of covariance was planned to examine the relationship between need-based pediatric psychology service use and spending for inpatient admissions, emergency department (ED) visits, and outpatient visits...
February 26, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28338380/the-association-between-physical-activity-with-cognitive-function-and-brain-derived-neurotrophic-factor-in-people-with-parkinson-s-disease-a-pilot-study
#3
Hanan Khalil, Mahmoud A Alomari, Omar Khabour, Aya Al-Hieshan, Jawad A Bajwa
OBJECTIVE: To examine the effect of physical capacity, on the relationship of Brain-Derived Neurotrophic Factor (BDNF) with cognitive function in people with PD. METHODS: Serum BDNF levels were measured in 29 PD participants and 30 healthy controls. Cognitive function was assessed using the Montreal Cognitive Assessment (MOCA) scale. Physical capacity was evaluated using the six minute walk distance (6-MWD). Participants were categorized into low or high physical capacity group according to their 50(th) percentile 6-MWD...
March 24, 2017: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/28338319/postmetalated-zirconium-metal-organic-frameworks-as-a-highly-potent-bactericide
#4
Boushra Mortada, Tamara Abou Matar, Aya Sakaya, Hala Atallah, Zeinab Kara Ali, Pierre Karam, Mohamad Hmadeh
Metal-organic frameworks (MOFs) have emerged as an important class of hybrid organic-inorganic materials. One of the reasons they have gained remarkable attention is attributed to the possibility of altering them by postsynthetic modification, thereby providing access to new and novel advanced materials. MOFs have been applied in catalysis, gas storage, gas separation, chemical sensing, and drug delivery. However, their bactericidal use has rarely been explored. Herein, we developed a two-step process for the synthesis of zirconium-based MOFs metalated with silver cations as a potent antibacterial agent...
March 24, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28337048/validity-of-a-new-kit-measuring-salivary-lactate-dehydrogenase-level-for-screening-gingivitis
#5
Daisuke Ekuni, Mayu Yamane-Takeuchi, Kota Kataoka, Aya Yokoi, Ayano Taniguchi-Tabata, Hirofumi Mizuno, Hisataka Miyai, Yoko Uchida, Daiki Fukuhara, Yoshio Sugiura, Takaaki Tomofuji, Manabu Morita
Aim. The aim of this study was to determine the usefulness of a new kit that can evaluate salivary lactate dehydrogenase (LD) level in real time for screening gingivitis. Materials and Methods. The study included 70 systemic healthy volunteers [29 males and 41 females; mean age ± SD: 24.1 ± 2.6 years]. Resting saliva was collected from each participant and LD level was evaluated in real time using the kit (a color-changing sheet with an integer scale ranging from 1 to 10). A dentist measured probing pocket depth, clinical attachment level, and the proportion of sites with bleeding on probing (% BOP) at six sites on all teeth...
2017: Disease Markers
https://www.readbyqxmd.com/read/28335426/elevated-serum-hepcidin-levels-during-an-intensified-training-period-in-well-trained-female-long-distance-runners
#6
Aya Ishibashi, Naho Maeda, Daichi Sumi, Kazushige Goto
Iron is essential for providing oxygen to working muscles during exercise, and iron deficiency leads to decreased exercise capacity during endurance events. However, the mechanism of iron deficiency among endurance athletes remains unclear. In this study, we compared iron status between two periods involving different training regimens. Sixteen female long-distance runners participated. Over a seven-month period, fasting blood samples were collected during their regular training period (LOW; middle of February) and during an intensified training period (INT; late of August) to determine blood hematological, iron, and inflammatory parameters...
March 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28335230/fluorescent-nanocomposite-of-embedded-ceria-nanoparticles-in-crosslinked-pva-electrospun-nanofibers
#7
Nader Shehata, Soha Gaballah, Effat Samir, Aya Hamed, Marwa Saad
This paper introduces a new fluorescent nanocomposite of electrospun biodegradable nanofibers embedded with optical nanoparticles. In detail, this work introduces the fluorescence properties of PVA nanofibers generated by the electrospinning technique with embedded cerium oxide (ceria) nanoparticles. Under near-ultra violet excitation, the synthesized nanocomposite generates a visible fluorescent emission at 520 nm, varying its intensity peak according to the concentration of in situ embedded ceria nanoparticles...
June 1, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334600/undercover-power-of-endocannabinoids-postsynaptic-ion-channel-modulator
#8
Aya Matsui, Veronica A Alvarez
In this issue of Neuron, Gantz and Bean (2017) show that the endocannabinoid 2-arachidonoyl glycerol (2-AG) can directly alter the properties of native ion-channel Kv4.3 and accelerate the pacemaker activity of rodent dopamine neurons. These findings are one of the first demonstrations of postsynaptic, cell-autonomous actions of endocannabinoids in the mammalian brain.
March 22, 2017: Neuron
https://www.readbyqxmd.com/read/28334337/birth-outcomes-among-adolescent-and-young-adult-cancer-survivors
#9
Chelsea Anderson, Stephanie M Engel, Jennifer E Mersereau, Kristin Z Black, William A Wood, Carey K Anders, Hazel B Nichols
Importance: Cancer diagnosis and treatment may adversely affect reproductive outcomes among female cancer survivors. Objective: To compare the birth outcomes of adolescent and young adult cancer survivors (AYA [diagnosed at ages 15-39 years]) with those of women without a cancer diagnosis. Design, Setting, and Participants: The North Carolina Central Cancer Registry (CCR) was used to identify female AYA cancer survivors diagnosed from January 2000 to December 2013; CCR records were linked to statewide birth certificate files from January 2000 to December 2014 to identify postdiagnosis live births to AYA survivors (n = 2598)...
March 23, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28332006/prenatal-nicotine-exposure-decreases-the-release-of-dopamine-in-the-medial-frontal-cortex-and-induces-atomoxetine-responsive-neurobehavioral-deficits-in-mice
#10
Tursun Alkam, Takayoshi Mamiya, Nami Kimura, Aya Yoshida, Daisuke Kihara, Yuki Tsunoda, Yuki Aoyama, Masayuki Hiramatsu, Hyoung-Chun Kim, Toshitaka Nabeshima
Increased risk of attention-deficit/hyperactivity disorder (AD/HD) is partly associated with the early developmental exposure to nicotine in tobacco smoke. Emerging reports link tobacco smoke exposure or prenatal nicotine exposure (PNE) with AD/HD-like behaviors in rodent models. We have previously reported that PNE induces cognitive behavioral deficits in offspring and decreases the contents of dopamine (DA) and its turnover in the prefrontal cortex (PFC) of offspring It is well known that the dysfunction of DAergic system in the brain is one of the core factors in the pathophysiology of AD/HD...
March 23, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28331797/paradoxical-response-with-increased-tumor-necrosis-factor-%C3%AE-levels-to-anti-tuberculosis-treatment-in-a-patient-with-disseminated-tuberculosis
#11
Sho Watanabe, Yugo Kaneko, Hironori Kawamoto, Tomoki Maehara, Yuri Baba, Ikumi Fujisaki, Nayuta Saito, Kai Ryu, Aya Seki, Tsugumi Horikiri, Akira Kinoshita, Hiroshi Takeda, Keisuke Saito, Kazuyosi Kuwano
It has been reported that tuberculosis (TB) worsens after cessation of tumor necrosis factor-α inhibitors and starting anti-TB treatment. Little is known about the immunological pathogenesis of this paradoxical response (PR). We report the first case of a TB patient in whom PR occurred concurrently with elevation of circulating tumor necrosis factor-α (TNFα) levels. A 75-year-old woman, who had been treated with adalimumab for SAPHO syndrome, developed disseminated TB. Soon after administration of anti-TB treatment (isoniazid, rifampicin, pyrazinamide, and ethambutol), and after discontinuation of adalimumab, a PR occurred...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28331145/modified-marionette-technique-for-laparoscopic-colorectal-surgery
#12
Seiichi Shinji, Hayato Kan, Takeshi Yamada, Michihiro Koizumi, Aya Yamagishi, Yasuyuki Yokoyama, Goro Takahashi, Takuma Iwai, Keisuke Hara, Kohki Takeda, Keiichiro Ohta, Eiji Uchida
INTRODUCTION: Single-port laparoscopic surgery has some technical limitations with respect to control of the forceps inserted through the single-access site, which results in increased internal collisions due to coaxial alignment of the instruments, as well as and decreased range of motion and visualization. To overcome these limitations, we employ a "modified marionette technique" as a way to carry out laparoscopic colorectal surgery. Materials and Surgical Technique: The procedures for the modified marionette technique are performed as follows: An Internal Organ Retractor (IOR)™ and an atraumatic clip designed to firmly grasp tissue, with 1-0 nylon thread, are inserted through a 12-mm trocar and secured in place where adequate visualization and traction for cutting with a radio knife is required...
2017: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/28330405/the-fukushima-nuclear-accident-affected-mothers-depression-but-not-maternal-confidence
#13
Aya Goto, Evelyn J Bromet, Misao Ota, Akira Ohtsuru, Seiji Yasumura, Keiya Fujimori
The Fukushima nuclear power plant accident caused widespread radiation contamination. Mothers of young children were at risk of negative emotional and mental health consequences. Using data from 2 independent prefecture-wide surveys of pregnant women, we examined the associations of disaster-related stressors with both maternal self-confidence and depressive symptoms. Two postal surveys were conducted targeting women who registered their pregnancies in Fukushima Prefecture (n = 6686 in 2012 and n = 6423 in 2013)...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28330403/communicating-with-residents-about-risks-following-the-fukushima-nuclear-accident
#14
Michio Murakami, Akiko Sato, Shiro Matsui, Aya Goto, Atsushi Kumagai, Masaharu Tsubokura, Makiko Orita, Noboru Takamura, Yujiro Kuroda, Sae Ochi
The Fukushima nuclear accident in March 2011 posed major threats to public health. In response, medical professionals have tried to communicate the risks to residents. To investigate forms of risk communication and to share lessons learned, we reviewed medical professionals' activities in Fukushima Prefecture from the prefectural level to the individual level: public communication through Fukushima Health Management Surveys, a Yorozu ("general") health consultation project, communications of radiological conditions and health promotion in Iitate and Kawauchi villages, dialogues based on whole-body counter, and science communications through online media...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28330402/fukushima-mothers-concerns-and-associated-factors-after-the-fukushima-nuclear-power-plant-disaster
#15
Shinya Ito, Aya Goto, Kayoko Ishii, Misao Ota, Seiji Yasumura, Keiya Fujimori
This study aimed to clarify the frequency of and temporal changes in the content of mothers' free written opinions obtained in the Fukushima Health Management Survey Pregnancy and Birth Survey from 2011 to 2013. A self-administered questionnaire was mailed to women who delivered babies in Fukushima Prefecture. The questionnaire asked about maternal and child health. Expression of mothers' concerns about radiation decreased over time. Common to the top 5 codes across the 3 years were "radiation effect on fetus and infant" and "information provision including survey results...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28330401/pregnancy-and-birth-survey-of-the-fukushima-health-management-survey
#16
Kayoko Ishii, Aya Goto, Misao Ota, Seiji Yasumura, Keiya Fujimori
The Pregnancy and Birth Survey was started by Fukushima Medical University as part of the Fukushima Health Management Survey in 2011 in order to assess the physical and mental health of mothers and provide parenting support (telephone counseling) for those in need. The present study reviewed the major findings from 4 annual surveys conducted from 2011 to 2014. Overall proportions of preterm deliveries, low birth weight infants, and congenital anomalies in the first year were almost the same as those in national surveillance data...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28329009/the-expression-and-localization-of-rnase-and-rnase-inhibitor-in-blood-cells-and-vascular-endothelial-cells-in-homeostasis-of-the-vascular-system
#17
Ayaka Ohashi, Aya Murata, Yuichiro Cho, Shizuko Ichinose, Yuriko Sakamaki, Miwako Nishio, Osamu Hoshi, Silvia Fischer, Klaus T Preissner, Takatoshi Koyama
RNA may be released from vascular cells including endothelial cells in the event of injury and in vascular disease. Extracellular RNAs have been recognized as novel procoagulant and permeability-increasing factors. Extracellular RNA may function as inflammatory host alarm signals that serve to amplify the defense mechanism, but it may provide important links to thrombus formation. Extracellular RNA is degraded by RNase. We propose that RNase and its inhibitor RNase inhibitor (RI) act as modulators of homeostasis in the vasculature to control the functions of extracellular RNA...
2017: PloS One
https://www.readbyqxmd.com/read/28328172/acute-lymphoblastic-leukemia-in-adolescents-and-young-adults
#18
REVIEW
Michael E Rytting, Elias J Jabbour, Susan M O'Brien, Hagop M Kantarjian
Acute lymphoblastic leukemia (ALL) in the adolescent and young adult (AYA) population is a difficult clinical problem. The AYA population, generally regarded as patients aged 15 to 39 years, currently draws a good deal of attention, particularly in the area of therapy selection. The current trend is to treat this group of patients with leukemia regimens based on pediatric protocols, and results comparing pediatric approaches versus adult approaches to treatment are maturing. Results are pending from a large US trial in which pediatric-based treatment is given to AYA patients with ALL...
March 22, 2017: Cancer
https://www.readbyqxmd.com/read/28326342/short-term-intermittent-administration-of-parathyroid-hormone-facilitates-osteogenesis-by-different-mechanisms-in-cancellous-and-cortical-bone
#19
Kenji Ogura, Tadahiro Iimura, Yuji Makino, Ayano Sugie-Oya, Aya Takakura, Ryoko Takao-Kawabata, Toshinori Ishizuya, Keiji Moriyama, Akira Yamaguchi
Intermittent administration of human parathyroid hormone (1-34)[hPTH(1-34)] induces anabolic action on the bones. To understand the mechanism underlying the early phase of hPTH(1-34)-induced anabolic action, we investigated the expression profiles of osterix and sclerostin after short-term intermittent administration of hPTH(1-34) using immunohistochemistry in adult rats. In the cancellous bone, hPTH(1-34) administration greatly increased the number of osterix-positive cells in the bone marrow on day 1, but the cells gradually decreased on days 3 and 5...
December 2016: Bone Reports
https://www.readbyqxmd.com/read/28326211/early-onset-signet-ring-cell-adenocarcinoma-of-the-colon-a-case-report-and-review-of-the-literature
#20
Maliha Khan, Krittiya Korphaisarn, Aneeqa Saif, Wai C Foo, Scott Kopetz
Colorectal cancer (CRC) remains the second leading cause of cancer-related deaths in the United States. While a decline has been observed in the older population, the occurrence of CRC in the adolescent and young adult (AYA) population has increased over the past two decades. The histopathologic characteristics and clinical behavior of CRC in AYA patients have been shown to be distinct from those of CRC in older adults. The rarer subtypes of CRC such as mucinous adenocarcinoma and signet-ring cell carcinoma are associated with a poorer prognosis compared to the more common subtypes...
2017: Case Reports in Oncological Medicine
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