Read by QxMD icon Read

subclinical hypothyroidism

Changhwan Seo, Seonghun Kim, Misol Lee, Min-Uk Cha, Hyoungnae Kim, Seohyun Park, Hae-Ryong Yun, Jong Hyun Jhee, Youn Kyung Kee, Seung Hyeok Han, Tae-Hyun Yoo, Shin-Wook Kang, Jung Tak Park
OBJECTIVE: Patients with diabetic nephropathy (DMN) have an increased risk of cardiovascular disease (CVD). However, strategies to reduce this risk are limited. Thyroid hormone replacement therapy (THRT) in patients with hypothyroidism has been shown to reduce several surrogate markers of CVD. Therefore, we performed a study to determine if THRT would reduce CVD risk in patients with subclinical hypothyroidism (SCH) and DMN. METHODS: This was a retrospective, nonrandomized study of patients with type 2 diabetes, DMN, and SCH...
March 2018: Endocrine Practice
Kecheng Yao, Tianming Zhao, Linghai Zeng, Jianming Yang, Yanqun Liu, Qian He, Xiulan Zou
It has been reported that subclinical hypothyroidism (SCH) is closely related to subclinical atherosclerosis. According to the impact of SCH on noninvasive markers of cardiovascular risk, we fulfilled a meta-analysis of included studies to provide an integrated overview. We searched electronic databases and included all relevant studies involving SCH and epicardial adipose tissue (EAT), carotid intima-media thickness (CIMT), pulse wave velocity (PWV), flow-mediated dilation (FMD) and glyceryl trinitrate-induced dilation (GNT- induced dilation)...
March 15, 2018: Scientific Reports
Jin Yang, Yang Liu, Hongjie Liu, Heming Zheng, Xiaofeng Li, Lin Zhu, Zhe Wang
OBJECTIVE: The study aimed to explore the effects of maternal iodine status and thyroid diseases on adverse pregnancy outcomes. METHODS: A prospective study was conducted on 2347 pregnant women, who provided 2347 urinary samples tested for iodine, 1082 serum samples tested for thyroid function, and 2347 questionnaires about demographic information. Their pregnancy outcomes were recorded and compared between different urinary iodine concentration (UIC) and thyroid function groups...
May 2018: Journal of Trace Elements in Medicine and Biology
Shatha A Al Shanqeeti, Yasser N Alkhudairy, Alwaleed A Alabdulwahed, Anwar E Ahmed, Maysoon S Al-Adham, Naveed M Mahmood
To estimate the prevalence of subclinical hypothyroidism (SCH) in Saudi Arabia and assess the need for an SCH screening program. Methods: This cross-sectional study was conducted at King Abdulaziz Medical City and the Khashmulaan Clinic at the National Guard Health Affairs, Riyadh, Saudi Arabia in August 2016. All women attending the antenatal clinics were  invited to participate in the study. In addition, data were retrieved from the files of pregnant women who had been screened for hypothyroidism from January 2016 to August 2016...
March 2018: Saudi Medical Journal
Tatjana Barišić, Vjekoslav Mandić, Anja Vasilj, Dejan Tiric
OBJECTIVE: To determine the frequency of subclinical hypothyroidism in women with pathological pregnancies and the association between elevated thyroid-stimulating hormone (TSH) and pregnancy outcome. SUBJECTS AND METHODS: A cross-sectional prospective study investigated value of TSH and free thyroxine (FT4) in: 1. pregnant women with hypertension (HTA) (N = 62) or preeclampsia (PE) (N = 50), 2.women with gestational diabetes mellitus (GDM) (N = 92) in pregnancy and 3...
March 14, 2018: Journal of Maternal-fetal & Neonatal Medicine
Subhodip Pramanik, Sujoy Ghosh, Pradip Mukhopadhyay, Rana Bhattacharjee, Bidisha Mukherjee, Samim Ali Mondal, Ipsita Ghosh, Ranajit Bari, Subhankar Chowdhury
Objective: Type 2 diabetes mellitus and thyroid dysfunction (TD) are two major public health endocrine problem, but the prevalence of TD and iodine status in patients with T2 DM in India is less studied. The study objective was to explore the prevalence of TD and to evaluate iodine health in type 2 diabetes patients attending a tertiary care center in Eastern India. Methods: Consecutive 100 patients with diabetes attending outpatient department were evaluated clinically and biochemically (thyrotropin [TSH], free thyroxine, anti-TPO antibody, and urinary iodine)...
January 2018: Indian Journal of Endocrinology and Metabolism
Jeong-Min Lee, Jeonghoon Ha, Kwanhoon Jo, Yejee Lim, Min-Hee Kim, Chan-Kwan Jung, So-Lyung Jung, Moo-Il Kang, Bong-Yun Cha, Dong-Jun Lim
Background/Aims: Lymphocytic thyroiditis as cytology diagnosis from fine needle aspiration (FNA) is frequently detected in patients with thyroid nodules. However, the clinical outcome for upcoming hypothyroid events has been rarely clarified in euthyroid patients. Methods: We retrospectively reviewed the data of patient who had lymphocytic thyroitidis on FNA cytology of thyroid nodule from January 2005 to December 2010 at a tertiary referral hospital. In total, 109 patients with follow-up thyroid function tests (TFT) were enrolled...
March 13, 2018: Korean Journal of Internal Medicine
Ronit Koren, Yifat Wiener, Karen Or, Carlos A Benbassat, Shlomit Koren
OBJECTIVES: To study the current practices in the management of subclinical hypothyroidism (SCH) and thyroid nodules during pregnancy of obstetricians/gynecologists (OB/GYNs) and endocrinologists in Israel. METHODS: An electronic questionnaire was sent by email to all members of the Israeli Endocrine Society and the Israel Society of Obstetrics and Gynecology. Questionnaires included demographic data and clinical scenarios with questions regarding the screening and management of pregnant women with SCH, hypothyroxinemia, and a palpable thyroid nodule...
March 2018: Israel Medical Association Journal: IMAJ
Daniela Metro, Valeria Cernaro, Mattia Papa, Salvatore Benvenga
Some natural compounds decrease serum levels of thyroid autoantibodies, but results are inconsistent and thyroid function has been evaluated infrequently; moreover, the effects of Aloe on thyroid autoimmunity and function have been examined in very few studies. This study stems from the observation of one co-author, who has Hashimoto's thyroiditis (HT)-related subclinical hypothyroidism (SCH). Upon checking her biochemical thyroid panel when taking daily Aloe barbardensis Miller juice (ABMJ) for thyroid-unrelated reasons, she noticed a decrease in serum thyroperoxidase autoantibodies (TPOAb) and thyrotropin (TSH) and an increase in serum free thyroxine (FT4)...
March 2018: Journal of Clinical & Translational Endocrinology
Jing Xue, Ru Feng, Haixia Fu, Qian Jiang, Hao Jiang, Jing Lu, Hui Liu, Jingwen Wang, Ting Niu, Xin Wang, Yandi Xie, Hao Wang, Lanping Xu, Kaiyan Liu, Xiaojun Huang, Xiaohui Zhang
The aim of the present study was to investigate the relationship between hypothyroidism and thrombocytopenia in hepatitis Brelated compensatory liver cirrhosis and to determine whether treatment with levothyroxine and prednisone is superior in a multicenter, open-label, observational study in China. In total, 125 consecutive hepatitis B-related compensated liver cirrhosis patients with severe thrombocytopenia accompanied by hypothyroidism were included. The patients were divided into four groups according to treatment strategy: a control group (n=29), a prednisone group (n=25), a levothyroxine group (n=32) and a prednisone plus levothyroxine group (n=39)...
March 8, 2018: Science China. Life Sciences
Jeonghoon Ha, Jeongmin Lee, Kwanhoon Jo, Dong Jun Lim, Moo Il Kang, Bong Yun Cha, Min Hee Kim
OBJECTIVE: To investigate the prevalence of subclinical hypothyroidism (SCH) in Korean adults and identify the risk factors for the occurrence of SCH by sex. DESIGN AND METHODS: This study used data from KNHANES VI, a cross-sectional, nationally representative survey, which comprises a health interview survey, a health examination survey, and a nutrition survey. To examine SCH, the thyroid-stimulating hormone (TSH) reference range was defined using both the range provided by the test kit manufacturer (SCH-M) and a population-based range (SCH-P)...
March 7, 2018: Endocrine Connections
Olcay Güngör, Ahmet Kağan Özkaya, Fatih Temiz
The aim of this study was to evaluate the thyroid function alterations in a group of epileptic children taking antiepileptic drugs. The study included a total of 183 pediatric epilepsy patients, aged 15 months-16 years, comprising 114 patients treated with valproic acid, 69 patients treated with phenobarbital, and 151 age-matched healthy volunteers as the control group. Serum levels of thyroid hormones were measured before the beginning of the antiepileptic therapy and after 12 months of treatment. Thyroid-stimulating hormone levels were significantly higher in the 12th month of phenobarbital and valproic acid treatment...
March 5, 2018: Acta Neurologica Belgica
Mukesh Kumar, Shilpi Modi, Poonam Rana, Pawan Kumar, Ratnesh Kanwar, Tarun Sekhri, Maria D'souza, Subash Khushu
Subclinical hypothyroidism (SCH) is characterized by mild elevation of thyroid stimulating hormone (TSH) (range 5-10 μIU/ml) and normal free triiodothyronine (FT3) and free thyroxine (FT4). The cognitive function impairment is well known in thyroid disorders such as hypothyroidism and hyperthyroidism, but little is known about deficits in brain functions in SCH subjects. Also, whether hormone-replacement treatment is necessary or not in SCH subjects is still debatable. In order to have an insight into the cognition of SCH subjects, intrinsic and extrinsic functional connectivity (FC) of the resting state networks (RSNs) was studied...
March 5, 2018: Journal of Neuroendocrinology
Agata Czarnywojtek, Nadia Sawicka-Gutaj, Izabela Miechowicz, Magdalena Borowska, Kosma Woliński, Maria Teresa Płazińska, Ariadna Zybek-Kocik, Ewa Straburzyńska-Migaj, Małgorzata Zgorzalewicz-Stachowiak, Aleksandra Hernik, Ewelina Szczepanek-Parulska, Marek Ruchała
INTRODUCTION: Cardiovascular diseases constitute a major cause of health problems and death in developed countries across the world. The increased value of the index of distribution of red blood cells volume (RDW) may be a prognostic marker in patients diagnosed with chronic heart failure (CHF). Hypothyroid patients present higher RDW values if compared to healthy controls. Taking into consideration that RDW might be both affected by thyroid status and CHF, we decided to determine the effect of concomitant hypothyroidism following radioiodine therapy (RIT) and CHF on hematological parameters...
March 5, 2018: Endokrynologia Polska
Harald Dobnig, Karin Amrein
Background Monopolar radiofrequency ablation is currently deemed an exotic treatment option for benign thyroid nodules in many central European countries. The aim of this study was to prospectively evaluate safety and efficacy of this method in a large patient cohort following its introduction in Austria. Patients and methods Peri- and post-interventional complications were analyzed for 277 patients. Efficacy was determined for 300 and 154 nodules at, respectively, 3 and 12 months post-treatment. All treatments were performed with an internally-cooled 18G radiofrequency electrode using a free-hand, so-called "moving-shot" technique following subcutaneous and local perithyroidal anesthesia...
February 28, 2018: Thyroid: Official Journal of the American Thyroid Association
Tinh-Hai Collet, Gerasimos P Sykiotis, Carole E Aubert, Christine Baumgartner, Manuel R Blum, Martin Feller, Christoph Stettler, Nicolas Rodondi
Subclinical hypothyroidism, defined as an elevated level of thyrotropin hormone (TSH) and normal thyroxin, is more frequent in women and above 65 years old. This condition is associated with an increased cardiovascular risk, in particular with TSH > 10,0 mIU/L. Although overt hypothyroidism is rare (prevalence of 0,3 %), levothyroxine has become the most prescribed medication in the US, while its indications are still debated. The European-funded TRUST trial showed no improvement in Hypothyroid Symptoms and Tiredness scores among patients ≥ 65 years with subclinical hypothyroidism treated with levothyroxine, and no improvement in blood pressure, weight, muscle strength and cognition...
February 28, 2018: Revue Médicale Suisse
Aris Giannakopoulos, Anni Katelaris, Maria Noni, Theodore Karakonstantakis, Christina Kanaka-Gantenbein, Stavros Doudounakis
Patients with cystic fibrosis (CF) commonly present with an elevated TSH concentration, suggesting subclinical hypothyroidism. Its relation to concomitant pancreatic insufficiency and its natural course upon initiation of enzyme replacement have not been adequately studied. Herein, we investigated the thyroid function in newly diagnosed infants with CF and monitored the course of thyroid function response to pancreatic enzyme substitution treatment. Fourteen, newly diagnosed infants with CF and pancreatic insufficiency, were followed every 6-8 weeks for 6 months ensuing onset of pancreatic enzyme substitution therapy...
February 27, 2018: European Journal of Pediatrics
Mary H Samuels
No abstract text is available yet for this article.
February 22, 2018: Journal of Clinical Endocrinology and Metabolism
Kamal K Solanki, Mahmood Al-Majmuei, Douglas H N White
BACKGROUND: Autoimmune thyroid disease affects 1% of the general population, and autoimmune thyroid antibodies are noted in up to 15%. OBJECTIVE: We hypothesized systemic sclerosis (SSc) is associated with higher prevalence of antithyroglobulin (anti-Tg) and anti-thyroid peroxidase (anti-TPO) antibodies) to justify monitoring of thyroid function for earlier detection and treatment. METHODS: Waikato Hospital SSc clinic patients were prospectively tested for thyroid function tests and antithyroid antibodies (ATAs)...
February 15, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
Marta Aguado Lobo, Elena Sierra Gonzalo, José Jiménez-Reyes
Eosinophilic annular erythema (EAE) is an uncommon eosinophilic dermatosis. Clinically it is characterized by recurrent episodes of annular or figurative plaques. The histopathological study shows a perivascular inflammatory infiltrate in the superficial and deep dermis, composed of lymphocytes and eosinophils. It was originally described in children. We report an adult woman who presented with recurrent erythematous annular plaques on the trunk and extremities. A biopsy showed a mainly perivascular lymphocytic infiltrate with numerous eosinophils in the dermis...
October 15, 2017: Dermatology Online Journal
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"