keyword
MENU ▼
Read by QxMD icon Read
search

Scrub typhus

keyword
https://www.readbyqxmd.com/read/28612320/scrub-typhus-causing-neonatal-hepatitis-with-acute-liver-failure-a-case-series
#1
Shailja Vajpayee, R K Gupta, M L Gupta
Neonatal hepatitis with acute liver failure due to varied etiology including various infections is reported in the past. Scrub typhus as a cause of neonatal hepatitis has rarely been reported in literature. A high index of clinical suspicion is required for early diagnosis and timely treatment. Severity and prognosis of the disease varies widely because several different strains of Orientia tsutsugamushi exist with different virulence. Delayed diagnosis can result in complication and significant morbidity and mortality...
June 14, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28607239/scrub-typhus-in-bhutan-a-synthesis-of-data-from-2009-to-2014
#2
REVIEW
Tshokey Tshokey, Tashi Choden, Ragunath Sharma
Scrub typhus is an acute, febrile illness, caused by the bacterium Orientia tsutsugamushi, that affects millions annually in the endemic Asia-Pacific region. In untreated cases, the case-fatality rates range from 6% to 35%. In Bhutan, there was a probable outbreak in Gedu in 2009, which resulted in heightened awareness of the disease. Nevertheless, information on scrub typhus in Bhutan is limited and scattered and the epidemiology has yet to be established. To report the current picture of scrub typhus in Bhutan, this review gathered data from scholarly databases, surveillance reports, the Annual health bulletin, research publications and laboratory test reports from hospitals...
September 2016: WHO South-East Asia Journal of Public Health
https://www.readbyqxmd.com/read/28604564/acute-cerebellitis-in-a-child-with-scrub-typhus
#3
Siyaram Didel, Aseem Basha M, Manisha Biswal, Renu Suthar, Naveen Sankhyan
No abstract text is available yet for this article.
July 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28601091/an-elisa-assay-using-a-combination-of-recombinant-proteins-from-multiple-strains-of-orientia-tsutsugamushi-offers-an-accurate-diagnosis-for-scrub-typhus
#4
Chien-Chung Chao, Zhiwen Zhang, Tatyana Belinskaya, Wilawan Thipmontree, Wiwit Tantibhedyangkul, Saowaluk Silpasakorn, Ekkarat Wongsawat, Yupin Suputtamongkol, Wei-Mei Ching
BACKGROUND: Scrub typhus (ST) is a disease caused by an obligate intracellular bacterium, Orientia tsutsugamushi, an organism that requires a BSL3 laboratory for propagation. The disease is hallmarked by an eschar at the site of the chigger bite, followed by the development of fever, malaise, myalgia, anorexia, and papulomacular rash. Indirect immunofluorescent assay (IFA) is the gold standard for scrub typhus diagnosis, however, the subjectivity of the assay, the need for a specialized laboratory and instruments has limited the wide use of the test in resource limited areas...
June 10, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28584437/severe-pediatric-acute-respiratory-distress-syndrome-due-to-scrub-typhus-successful-ventilation-with-airway-pressure-release-ventilation-mode-after-becoming-refractory-to-protective-ventilation
#5
Sudha Chandelia, Sarika Jain
Scrub typhus can affect lungs from mild illness like pneumonitis to a severe illness like acute respiratory distress syndrome (ARDS). Such patients may be very challenging to treat when their hypoxemia becomes severe and refractory to treatment. Main treatment is supportive in terms of mechanical ventilation. In adult ARDS, low tidal volume (TV) ventilation has been recommended, but there is no consensus on most effective ventilation mode in children. We present a case of a 12-year-old girl who developed severe ARDS (PO2/FiO2 ratio - 58), refractory to low TV ventilation...
May 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28531311/the-genotypes-of-orientia-tsutsugamushi-identified-in-scrub-typhus-patients-in-northern-vietnam
#6
Hang L K Nguyen, Hang T T Pham, Tinh V Nguyen, Phuong Vm Hoang, Mai T Q Le, Taichiro Takemura, Futoshi Hasebe, Daisuke Hayasaka, Akio Yamada, Kozue Hotta
Background: There are an estimated one million patients with scrub typhus in the Asia-Pacific region. There are few reports describing the incidence of scrub typhus in Vietnam. Methods: Blood samples collected from 63 patients clinically diagnosed as having scrub typhus from July 2015 to September 2016 were subjected to genotyping of Orientia tsutsugamushi. Results and Conclusions: Of these patients, 42 (67%) tested positive for O. tsutsugamushi, and the most common genotype was identified to be Karp (55%)...
March 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28529271/evidence-of-infection-with-leptospira-interrogans-and-spotted-fever-group-rickettsiae-among-rodents-in-an-urban-area-of-osaka-city-japan
#7
Kenta Shimizu, Rie Isozumi, Kazutoshi Takami, Isao Kimata, Kanae Shiokawa, Kumiko Yoshimatsu, Yoshimi Tsuda, Sanae Nishio, Jiro Arikawa
We examined 33 rodents captured in an urban area of Osaka City, Japan for IgG antibodies against Seoul virus, severe fever with thrombocytopenia syndrome virus, hepatitis E virus, Leptospira interrogans, Yersinia pestis, spotted fever, typhus and scrub typhus group rickettsiae. We found that 3 (9.1%) and 1 (3.0%) of the 33 rodents had antibodies against L. interrogans and spotted fever group rickettsiae, respectively. DNAs of leptospires were detected from 2 of the 3 seropositive rodents, but DNA of rickettsia was not detected...
May 22, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28500808/seroprevalence-of-scrub-typhus-typhus-and-spotted-fever-among-rural-and-urban-populations-of-northern-vietnam
#8
Nguyen Vu Trung, Le Thi Hoi, Nguyen Thi Hong Thuong, Tran Khanh Toan, Tran Thi Kieu Huong, Tran Mai Hoa, Annette Fox, Nguyen van Kinh, H Rogier van Doorn, Heiman F L Wertheim, Juliet E Bryant, Behzad Nadjm
AbstractRickettsial infections are recognized as important causes of fever throughout southeast Asia. Herein, we determined the seroprevalence to rickettsioses within rural and urban populations of northern Vietnam. Prevalence of individuals with evidence of prior rickettsial infections (IgG positive) was surprisingly low, with 9.14% (83/908) testing positive to the three major rickettsial serogroups thought to circulate in the region. Prevalence of typhus group rickettsiae (TG)-specific antibodies (6.5%, 58/908) was significantly greater than scrub typhus group orientiae (STG)- or spotted fever group rickettsiae (SFG)-specific antibodies (P < 0...
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28500798/persistent-sick-sinus-syndrome-in-scrub-typhus
#9
Lae-Young Jung, Ji-Young Yoon, Soo-Kyeong Song, Chang-Seop Lee
No abstract text is available yet for this article.
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28474627/scrub-typhus-in-uttarakhand-adjoining-uttar-pradesh-seasonality-clinical-presentations-predictors-of-mortality
#10
Anurag Bhargava, Reshma Kaushik, Rajeev Mohan Kaushik, Anita Sharma, Sohaib Ahmad, Minakshi Dhar, Garima Mittal, Sushant Khanduri, Priyannk Pant, Rajesh Kakkar
BACKGROUND & OBJECTIVES: Scrub typhus is a re-emerging mite-borne rickettsiosis, which continues to be underdiagnosed, with lethal consequences. The present study was conducted to determine the seasonality, clinical presentation and predictors of mortality in patients with scrub typhus at a tertiary care teaching hospital in northern India. METHODS: Scrub typhus was suspected in patients attending the hospital as per the standard case definition and serological evidence was obtained by performing an IgM ELISA...
December 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28474626/abundance-distribution-of-trombiculid-mites-orientia-tsutsugamushi-the-vectors-pathogen-of-scrub-typhus-in-rodents-shrews-collected-from-puducherry-tamil-nadu-india
#11
Sadanandane Candasamy, Elango Ayyanar, Kummankottil Paily, Patricia Anitha Karthikeyan, Agatheswaran Sundararajan, Jambulingam Purushothaman
BACKGROUND & OBJECTIVES: Human cases of scrub typhus are reported every year from Puducherry and adjoining areas in southern India. However, information on the presence of causative agent, Orientia tsutsugamushi, and its vectors is lacking. Hence, the objective of the study was to find out the vector as well as pathogen distribution in rodents and shrews present in the scrub typhus-reported areas in southern India. METHODS: Trombiculid mites were collected by combing rats and shrews collected using Sherman traps and identified to species level following standard taxonomical keys...
December 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28461826/effects-of-clarithromycin-treatment-in-scrub-typhus-in-children-comparison-with-chloramphenicol-and-azithromycin
#12
Min Lee, June Kim, Dae Sun Jo
PURPOSE: Chloramphenicol and tetracycline are not recommended for treating scrub typhus in pediatric patients because of potential side effects, such as aplastic anemia or tooth discoloration. While clarithromycin has recently been used in adults, few reports have been published on its effects in pediatric patients. We report the clinical profiles of pediatric scrub typhus and the effects of clarithromycin on scrub typhus in children. METHODS: We retrospectively analyzed medical records of 56 children with scrub typhus who were admitted between 2004 and 2013 to Chonbuk National University Hospital, Jeonju, Korea...
April 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/28449088/clinical-manifestations-of-scrub-typhus
#13
Senaka Rajapakse, Praveen Weeratunga, Sriharan Sivayoganathan, Sumadhya Deepika Fernando
The mite-borne rickettsial zoonosis scrub typhus is widely prevalent in parts of Southeast and Far East Asia, and northern Australia. The disease is an acute febrile illness, associated with rash and often an eschar, which responds dramatically to treatment with antibiotics. In some cases it results in a serious illness leading to multiple organ involvement and death. The disease manifestations are thought to result from a systemic vasculitis, caused by both direct effects of the organisms as well as an exaggerated immune response, although little is understood about its pathogenesis...
February 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28419138/clinical-significance-of-ngal-and-kim-1-for-acute-kidney-injury-in-patients-with-scrub-typhus
#14
In O Sun, Sung Hye Shin, A Young Cho, Hyun Ju Yoon, Mi Yok Chang, Kwang Young Lee
BACKGROUND: The aim of this study is to investigate the clinical significance of neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) for acute kidney injury (AKI) in patients with scrub typhus. METHODS: From 2014 to 2015, 145 patients were diagnosed with scrub typhus. Of these, we enrolled 138 patients who were followed up until renal recovery or for at least 3 months. We measured serum and urine NGAL and KIM-1 levels and evaluated prognostic factors affecting scrub typhus-associated AKI...
2017: PloS One
https://www.readbyqxmd.com/read/28412201/nitric-oxide-enhanced-the-growth-of-an-obligated-intracellular-bacterium-orientia-tsutsugamushi-in-murine-macrophages
#15
Motohiko Ogawa, Masaaki Satoh, Michiyo Kataoka, Shuji Ando, Masayuki Saijo
Orientia tsutsugamushi is the causative agent of scrub typhus. It is an obligate intracellular bacterium that grows only in eukaryotic cells. Macrophages play an important role in innate immunity by surveilling the human body for pathogens. In present study, it was demonstrated that O. tsutsugamushi propagated well in LPS-activated RAW 264.7 macrophages, but not in non-activated macrophages. In LPS-activated macrophages, the expression of Nos2, which encodes the inducible nitric oxide (NO) synthase (iNOS), was highly upregulated compared to those in non-activated macrophages...
April 12, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28407761/acute-phase-diagnosis-of-murine-and-scrub-typhus-in-belgian-travelers-by-polymerase-chain-reaction-a-case-report
#16
Caroline Theunissen, Lieselotte Cnops, Marjan Van Esbroeck, Ralph Huits, Emmanuel Bottieau
No abstract text is available yet for this article.
April 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28405985/clinical-profile-and-complications-of-scrub-typhus-hospital-based-study-in-sub-himalayan-region
#17
Ritesh Kumar, Surinder Thakur, Rajesh Bhawani, Anil Kanga, Asha Ranjan
BACKGROUND: Scrub typhus is a documented disease in Himachal Pradesh, but there have been no clinico-epidemiological studies in this area. The present study is done with IgM ELISA as a diagnostic test which has higher sensitivity and specificity as most of previous studies had used Weil Felix test as a diagnostic test. METHODOLOGY: This was a prospective observational study. All the patients more than 18 years of age with positive IgM ELISA for scrub typhus with or without eschar were included...
December 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28386493/dengue-and-scrub-typhus-coinfection-in-a-patient-presenting-with-febrile-illness
#18
Surendra Sapkota, Sudeep Bhandari, Subash Sapkota, Rabin Hamal
Dengue fever and scrub typhus are common causes of acute febrile illness of unclear origin in Asia. Though coinfections of many vector-borne diseases have been described, articles on dengue and scrub typhus coinfection are distinctly limited. In case of coinfection with dengue and scrub typhus, vigilant monitoring of vitals, platelets transfusion, and timely treatment with doxycycline are necessary. High degree of suspicion has to be made for coinfection in a patient presenting with febrile illness with thrombocytopenia and deranged laboratory parameters in postmonsoon season in endemic regions in Asia...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28361787/iap-guidelines-on-rickettsial-diseases-in-children
#19
Narendra Rathi, Atul Kulkarni, Vijay Yewale
OBJECTIVE: To formulate practice guidelines on rickettsial diseases in children for pediatricians across India. JUSTIFICATION: Rickettsial diseases are increasingly being reported from various parts of India. Due to low index of suspicion, nonspecific clinical features in early course of disease, and absence of easily available, sensitive and specific diagnostic tests, these infections are difficult to diagnose. With timely diagnosis, therapy is easy, affordable and often successful...
March 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28356672/scrub-typhus-meningitis-in-a-renal-transplant-recipient
#20
J Dhanapriya, T Dineshkumar, R Sakthirajan, S Murugan, V Jayaprakash, T Balasubramaniyan, N Gopalakrishnan
Scrub typhus is a rickettsial infection commonly seen in Asia. The clinical presentation ranges from nonspecific febrile illness to potentially fatal multiorgan involvement such as liver, kidney, or lung. Central nervous system involvement is uncommon. We report a 45-year-old female renal transplant recipient who presented with fever, headache, meningeal signs, graft dysfunction, and eschar. IgM antibodies against Orientia tsutsugamushi were positive by enzyme-linked immunosorbent assay. Despite oral doxycycline therapy for 5 days, she did not improve but responded well to intravenous azithromycin...
March 2017: Indian Journal of Nephrology
keyword
keyword
42302
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"