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Scrub typhus

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https://www.readbyqxmd.com/read/27908651/eschar-a-stepping-stone-to-scrub-typhus
#1
Shu-Chao Weng, Hung-Chang Lee, Jeng-Jung Chen, Yu-Jyun Cheng, Hsin Chi, Chien-Yu Lin
No abstract text is available yet for this article.
November 28, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27887623/generation-of-protective-immunity-against-orientia-tsutsugamushi-infection-by-immunization-with-a-zinc-oxide-nanoparticle-combined-with-scaa-antigen
#2
Na-Young Ha, Hyun Mu Shin, Prashant Sharma, Hyun Ah Cho, Chan-Ki Min, Hong-Il Kim, Nguyen Thi Hai Yen, Jae-Seung Kang, Ik-Sang Kim, Myung-Sik Choi, Young Keun Kim, Nam-Hyuk Cho
BACKGROUND: Zinc oxide nanoparticle (ZNP) has been applied in various biomedical fields. Here, we investigated the usage of ZNP as an antigen carrier for vaccine development by combining a high affinity peptide to ZNP. RESULTS: A novel zinc oxide-binding peptide (ZBP), FPYPGGDA, with high affinity to ZNP (K a  = 2.26 × 10(6) M(-1)) was isolated from a random peptide library and fused with a bacterial antigen, ScaA of Orientia tsutsugamushi, the causative agent of scrub typhus...
November 26, 2016: Journal of Nanobiotechnology
https://www.readbyqxmd.com/read/27886863/analysis-of-scrub-typhus-involvement-of-the-lung-by-bronchoalveolar-lavage-a-case-report
#3
Shih-Yuan Lin, Yosuke Matsuno, Masahiro Yokosawa, Takeshi Suzuki, Yuko Morishima, Tohru Sakamoto, Takayuki Sumida, Nobuyuki Hizawa
No abstract text is available yet for this article.
November 2016: Respiratory Investigation
https://www.readbyqxmd.com/read/27885295/scrub-typhus-an-emerging-neglected-tropical-disease-in-nepal
#4
B P Upadhyaya, G Shakya, S Adhikari, N Rijal, J Acharya, L Maharjan, B R Marasini
BACKGROUND: Scrub typhus is a neglected tropical disease and is under reported from Nepal. The objective of this study was to investigate the sero-epidemiology of scrub typhus in patients suffering from acute febrile illness. METHODS: A total of 434 specimens collected from July to November 2015 at National Public Health Laboratory (NPHL) were investigated for detection of immunoglobulin M (IgM) antibody to Orientiatsutsugamushi.The Scrub Typhus Detect TM kit (InBios, USA) was used to detect the antibodies to O...
May 2016: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/27883370/epstein-barr-virus-associated-hemophagocytic-syndrome-after-scrub-typhus-infection
#5
Jeong Woo Hong, Hyun Seon You, Tae Won Lee, Won Yong Jo, Bo Ra Kim, Young Sun Suh, In Gyu Bae, Oh Hyun Cho
There have been a small number of cases of scrub typhus-associated hemophagocytic syndrome (HPS), most of which were treated successfully using adequate antibiotics. Here, we report a case of Epstein-Barr virus (EBV)-associated HPS after scrub typhus infection that was not improved using antirickettsial treatment. A 73-year-old male who had been diagnosed with scrub typhus according to an eschar and a positive serology was transferred to our institution because of a persistent fever despite 7-day doxycycline therapy...
November 8, 2016: Infection & Chemotherapy
https://www.readbyqxmd.com/read/27834329/epidemiology-risk-factors-of-scrub-typhus-in-south-india
#6
George M Varghese, Deepa Raj, Mark R Francis, Rajiv Sarkar, Paul Trowbridge, Jayaprakash Muliyil
BACKGROUND & OBJECTIVES: Scrub typhus is a major public health threat in South and Southeastern Asian countries including India. Understanding local patterns of disease and factors that place individuals at risk is pivotal to future preventive measures against scrub typhus. The primary aim of this study was to identify specific epidemiological and geographical factors associated with an increased risk of developing scrub typhus in this region. METHODS: We mapped 709 patients from Tamil Nadu, Andhra Pradesh and Telangana who were admitted to the Christian Medical College (CMC) Hospital, Vellore, Tamil Nadu, India, for the period 2006-2011, assessed seasonality using monthly counts of scrub typhus cases, and conducted a case-control study among a subset of patients residing in Vellore...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27829876/scrub-typhus-in-pregnancy-maternal-and-fetal-outcomes
#7
Sudha J Rajan, Sowmya Sathyendra, Alice J Mathuram
Scrub typhus is an important unrecognized cause for undifferentiated acute febrile illness in India associated with poor fetal outcomes. Maternal and fetal outcomes among pregnant patients with scrub typhus presenting to a tertiary care university teaching hospital from January 2010 to July 2012 were studied. Scrub typhus was diagnosed by clinical criteria along with scrub ELISA positivity or an eschar. In total, 33 of 738 patients (4.5%) who were diagnosed with scrub typhus were pregnant; 57.6% were in the third trimester, 27...
December 2016: Obstetric Medicine
https://www.readbyqxmd.com/read/27790497/an-unusual-presentation-of-scrub-typhus
#8
Giridhar Reddy Banda, Srikrishna Raghavendra Boddu, Priyanka Ballal, Jayaprakash Belle
Presentation of scrub typhus associated with brachial neuritis is extremely rare with only a few cases reported so far. Here, we report a case of a 45-year-old female who presented with fever and right shoulder pain. Laboratory parameters showed leucocytosis with ELISA and PCR for scrub typhus positive. Electromyography (EMG) and Nerve Conduction Velocity (NCV) study was suggestive of brachial neuritis. She was given doxycycline therapy for 10 days following which her shoulder pain resolved.
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27788693/meteorological-factors-affecting-scrub-typhus-occurrence-a-retrospective-study-of-yamagata-prefecture-japan-1984-2014
#9
J Seto, Y Suzuki, R Nakao, K Otani, K Yahagi, K Mizuta
Climate change, by its influence on the ecology of vectors might affect the occurrence of vector-borne diseases. This study examines the effects of meteorological factors in Japan on the occurrence of scrub typhus, a mite-borne zoonosis caused by Orientia tsutsugamushi. Using negative binomial regression, we analysed the relationships between meteorological factors (including temperature, rainfall, snowfall) and spring-early summer cases of scrub typhus in Yamagata Prefecture, Japan, during 1984-2014. The average temperature in July and August of the previous year, cumulative rainfall in September of the previous year, snowfall throughout the winter, and maximum depth of snow cover in January and February were positively correlated with the number of scrub typhus cases...
October 28, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27774344/scrub-typhus-in-nepal
#10
Niranjan Nayak
No abstract text is available yet for this article.
June 2016: Nepal journal of epidemiology
https://www.readbyqxmd.com/read/27767909/severe-fever-with-thrombocytopenia-syndrome-in-patients-suspected-of-having-scrub-typhus
#11
Yu Mi Wi, Hye In Woo, Dahee Park, Keun Hwa Lee, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song
To determine prevalence of severe fever with thrombocytopenia syndrome in South Korea, we examined serum samples from patients with fever and insect bite history in scrub typhus-endemic areas. During the 2013 scrub typhus season, prevalence of this syndrome among patients suspected of having scrub typhus was high (23.0%), suggesting possible co-infection.
November 2016: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27763480/chest-radiographic-manifestations-of-scrub-typhus
#12
Kpp Abhilash, P R Mannam, K Rajendran, R A John, P Ramasami
BACKGROUND AND RATIONALE: Respiratory system involvement in scrub typhus is seen in 20-72% of patients. In endemic areas, good understanding and familiarity with the various radiologic findings of scrub typhus are essential in identifying pulmonary complications. MATERIALS AND METHODS: Patients admitted to a tertiary care center with scrub typhus between October 2012 and September 2013 and had a chest X ray done were included in the analysis. Details and radiographic findings were noted and factors associated with abnormal X-rays were analyzed...
October 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27757247/an-outbreak-investigation-of-scrub-typhus-in-western-province-solomon-islands-2014
#13
Michael Marks, Cynthia Joshua, Jenny Longbottom, Katherine Longbottom, Alison Sio, Elliot Puiahi, Greg Jilini, John Stenos, Tenneth Dalipanda, Jennie Musto
OBJECTIVE: To identify the etiology and risk factors of undifferentiated fever in a cluster of patients in Western Province, Solomon Islands, May 2014. METHODS: An outbreak investigation with a case control study was conducted. A case was defined as an inpatient in one hospital in Western Province, Solomon Islands with high fever (> 38.5 °C) and a negative malaria microscopy test admitted between 1 and 31 May 2014. Asymptomatic controls matched with the cases residentially were recruited in a ratio of 1:2...
January 2016: Western Pacific Surveillance and Response Journal: WPSAR
https://www.readbyqxmd.com/read/27753778/acute-paraparesis-due-to-lumbosacral-radiculopathy-with-concomitant-meningitis-unusual-presentation-of-scrub-typhus
#14
Mamta Muranjan, Sunil Karande
No abstract text is available yet for this article.
November 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27731577/concurrent-infection-with-scrub-typhus-dengue-and-malaria-in-an-immunocompetent-young-male
#15
Meenaxi Sharda, Shivraj Meena, Anil Soni, Harish Nigam, Anuraj Singh
No abstract text is available yet for this article.
March 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27731554/pattern-of-clinical-presentation-laboratory-findings-and-mortality-risk-among-patients-of-scrub-typhus-in-western-himalayas
#16
Sanjay K Mahajan, Rajiv Raina, Balraj Singh, Dig Vijay Singh, Anil Kanga, Ashok Sharma, Satinder S Kaushal
OBJECTIVE: To study the pattern of the clinical presentation, laboratory findings and mortality risk among patients infected by scrub typhus in Western Himalayan region of India. METHODS: We studied all serologically confirmed cases of scrub typhus admitted to our hospital from July 2010 through December 2011. Presence of IgM antibodies to scrub typhus antigens by ELISA was considered as serological confirmation of the diagnosis. We observed the symptoms, signs, laboratory findings, risk factors for death from the time of admission till discharge/death...
March 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27730787/scrub-typhus-presenting-as-acute-cerebellitis
#17
Sanjay K Mahajan, Sudhir Sharma, Madan Kaushik, Rajiv Raina, Preyander Thakur, Gagan Preet Taneja, Jai Bharat Sharma
Scrub typhus is known to present with varied presentation including involvement of central nervous system. We present a case who presented with fever and features of isolated cerebellitis. Serum showed IgM antibodies to scrub typhus by ELISA. Patient showed rapid response to doxycycline and dexamethasone.
February 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27730774/infections-and-thrombocytopenia
#18
Falguni Parikh
Febrile patient with thrombocytopenia is commonly encountered by physicians especially during monsoon and perimonsoon period. Infections with protozoa, bacteria and viruses can cause thrombocytopenia with or without disseminated intravascular coagulation. Commonly dengue, malaria, scrub typhus and other rickettsial infections, meningococci, leptospira and certain viral infections present as fever with thrombocytopenia. Occasionally these patients can go on to develop a stormy course with multiorgan dysfunction requiring intensive care unit admission associated with high morbidity and mortality...
February 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27728719/scrub-typhus-with-hyperacusis-and-tinnitus
#19
Alfia Rachel Kaki, Sowmya Satyendra
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27728427/scrub-typhus-presenting-as-capillary-leak-syndrome
#20
Viswanath Mv, Chaitanya Gb
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
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