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Jennifer K Vanos, Grant R McKercher, Kylie Naughton, Marc Lochbaum
Childhood exposure to ultraviolet radiation (UVR) is a major risk factor for the development of melanoma later in life. However, it is challenging to accurately determine personal outdoor exposure to UVR, specifically erythemally weighted UVR (UVEry ), due to technological constraints, variable time-activity patterns, and the influence of outdoor environmental design. To address this challenge, this study utilized mobile and stationary techniques to examine the UVEry exposures of 14 children in a schoolyard in Lubbock, TX, in spring 2016...
January 18, 2017: Photochemistry and Photobiology
Jeremy L Norris, Melissa A Farrow, Danielle B Gutierrez, Lauren D Palmer, Nicole Muszynski, Stacy D Sherrod, James C Pino, Jamie L Allen, Jeffrey M Spraggins, Alex L R Lubbock, Ashley Jordan, William Burns, James C Poland, Carrie Romer, M Lisa Manier, Yuan-Wei Nei, Boone M Prentice, Kristie L Rose, Salisha Hill, Raf Van de Plas, Tina Tsui, Nathaniel M Braman, M Ray Keller, Stacey A Rutherford, Nichole Lobdell, Carlos F Lopez, D Borden Lacy, John A McLean, John P Wikswo, Eric P Skaar, Richard M Caprioli
An understanding of how cells respond to perturbation is essential for biological applications; however, most approaches for profiling cellular response are limited in scope to pre-established targets. Global analysis of molecular mechanism will advance our understanding of the complex networks constituting cellular perturbation and lead to advancements in areas, such as infectious disease pathogenesis, developmental biology, pathophysiology, pharmacology, and toxicology. We have developed a high-throughput multiomics platform for comprehensive, de novo characterization of cellular mechanisms of action...
February 9, 2017: Journal of Proteome Research
Bart W Durham, Lucy Porter, Allie Webb, Joshua Thomas
This study investigated patterns of Escherichia coli in urban lakes in Lubbock, Texas. Specific objectives were to (1) document seasonal patterns in abundance of E. coli over a 3-year period, (2) identify environmental factors, including effects of migratory geese and artificial aeration devices that may influence E. coli abundance, and (3) determine if E. coli abundance over time was similar for individual lakes. Water samples were collected monthly for 36 months from six lakes, three of which contained artificial aeration devices (fountains)...
December 2016: Journal of Water and Health
Yana Puckett, Benedicto C Baronia
With the recent advances in eye tracking technology, it is now possible to track surgeons' eye movements while engaged in a surgical task or when surgical residents practice their surgical skills. Several studies have compared eye movements of surgical experts and novices and developed techniques to assess surgical skill on the basis of eye movement utilizing simulators and live surgery. None have evaluated simultaneous visual tracking between an expert and a novice during live surgery. Here, we describe a successful simultaneous deployment of visual tracking of an expert and a novice during live laparoscopic cholecystectomy...
September 20, 2016: Curēus
Vance Holliday, Todd Surovell, Eileen Johnson
The Younger Dryas Impact Hypothesis (YDIH) states that North America was devastated by some sort of extraterrestrial event ~12,800 calendar years before present. Two fundamental questions persist in the debate over the YDIH: Can the results of analyses for purported impact indicators be reproduced? And are the indicators unique to the lower YD boundary (YDB), i.e., ~12.8k cal yrs BP? A test reported here presents the results of analyses that address these questions. Two different labs analyzed identical splits of samples collected at, above, and below the ~12...
2016: PloS One
Walter L Miller
Douglas M. (Doug) Stocco is Professor Emeritus at Texas Tech University Health Sciences Center in Lubbock, TX, and is internationally renowned for his work characterizing the steroidogenic acute regulatory protein, StAR. Stocco's laboratory isolated and cloned StAR from mouse Leydig MA-10 cells, collaborated on the demonstration that StAR mutations cause congenital lipoid adrenal hyperplasia, and delineated much of what is known about the intracellular pathways that regulate its production. This work resolved a decades-long quest to identify the mechanism underlying the acute regulation of steroidogenesis...
June 21, 2016: Molecular and Cellular Endocrinology
Supannee Rassameehiran, Charoen Mankongpaisarnrung, Grerk Sutamtewagul, Saranapoom Klomjit, Ariwan Rakvit
OBJECTIVES: The purpose of our study was to identify clinical parameters associated with readmissions within 90 days in patients with hepatic encephalopathy (HE). METHODS: We reviewed electronic medical records of patients admitted between January 1, 2010 and September 30, 2013 at University Medical Center, Lubbock, Texas. Inclusion criteria were admission to the hospital with diagnosis of HE in patients older than 18 years. We compared the patients with readmission within 90 days with patients with no readmission using routine clinical data...
June 2016: Southern Medical Journal
Annette N Boles, Hafiz Khan, Taylor A Lenzmeier, Veronica A Molinar-Lopez, James C Ament, Kate L TeBrink, Kathleen Stonum, Ruben M Gonzales, P Hemachandra Reddy
The objective of our study was to evaluate the exercise and educational intervention in the city of Lubbock via GET FiT Lubbock (GFL) program. The GFL program was designed to increase exercise and educational opportunities, which positively impact health risk factors in Lubbock residents. The GFL program design included the recruitment of subjects to participate on a team that consisted of four individuals, each subject tracked their exercise minutes, and their educational session attendance. The tracking of exercise and educational sessions was done on the GFL website...
2016: Frontiers in Aging Neuroscience
Raghavendra G Amachawadi, Milton Thomas, Tiruvoor G Nagaraja, Joy Scaria
The genome sequencing of 13 Salmonella enterica subsp. enterica serovar Lubbock strains isolated from liver abscesses of feedlot cattle is reported here. The availability of these genomes will help to further understand the etiologic role of Salmonella strains in liver abscesses of cattle and will serve as references in microbial trace-back studies to improve food safety.
2016: Genome Announcements
Martin Sojka, Ivana Valachova, Marcela Bucekova, Juraj Majtan
Many clinically relevant biofilms are polymicrobial. Examining the effect of antimicrobials in a multi-species biofilm consortium is of great clinical importance. The goal of this study was to investigate the effect of different honey types against bacterial wound pathogens grown in multi-species biofilm and to test the antibiofilm activity of honey defensin-1 in its recombinant form. Modified Lubbock chronic wound biofilm formed by four bacterial species (Staphylococcus aureus, Streptococcus agalactiae, Pseudomonas aeruginosa, Enterococcus faecalis) was used for evaluation of honey and recombinant bee-derived defensin-1 antibiofilm efficacy...
February 8, 2016: Journal of Medical Microbiology
Betsy Goebel Jones, Steven L Berk
Meeting Texas' future health care needs will be challenging, including the goal for a physician workforce more balanced toward primary care. To help expand the primary care physician workforce, Texas Tech University Health Sciences Center (TTUHSC) School of Medicine developed the Family Medicine Accelerated Track (FMAT), a three-year curriculum that culminates in the MD degree and links medical students to family medicine residency programs at TTUHSC campuses in Lubbock, Amarillo, or the Permian Basin (Odessa and Midland)...
February 1, 2016: Texas Medicine
Cesar J Garcia, Oscar A Lopez, Sameer Islam, Mohamed Othman, Yi Jia, Zuber D Mulla, Marc J Zuckerman
BACKGROUND: The use of gastrointestinal endoscopy in geriatric patients is rising as an increasing proportion of the population is reaching an advanced age. Most studies of endoscopic retrograde cholangiopancreatography (ERCP) in the elderly have been done in tertiary care or referral centers. METHODS: We analyzed the clinical and endoscopic data on all ERCPs in patients aged 65 years and older in a retrospective review of medical records of patients at the county hospitals in El Paso and Lubbock, Texas between 2004 and 2008...
January 2016: American Journal of the Medical Sciences
D L Kerns, J A Yates, B A Baugh
Cotton aphid, Aphis gossypii Glover (Hemiptera: Aphididae), is a common pest of cotton throughout much of the world. In the United States, insecticide applications targeting cotton aphid in cotton are common in the Mid-South, Texas, and California. Cotton aphid population dynamics data were collected from eight insecticide efficacy trials conducted in Lubbock, TX, over a 4-yr period. Among the field populations in the nontreated plots, the instantaneous rate of population growth averaged 0.56 ± 0.608, and the mean population doubling time was 3...
August 2015: Journal of Economic Entomology
P Hemachandra Reddy, Joan Blackmon, Veronica Molinar-Lopez, Clay Ament, Maria Manczak, Ramesh Kandimalla, Xianglin Yin, Akhilesh Pandey, Chandra Sekhar Kuruva, Rui Wang, David Fry, Carrah Osborn, Kathleen Stonum, Kandi Quesada, Ruben Gonzales, Annette Boles
The Garrison Institute on Aging (GIA) is an established institute within Texas Tech University Health Sciences Center, whose mission is to promote healthy aging through cutting-edge research on Alzheimer's disease (AD) and other diseases of aging through innovative educational opportunities for students, clinicians, researchers, health care professionals, and the public. The GIA has multiple programs, including both research and education on healthy aging and AD, community outreach, caregiving, the Retired Senior Volunteer Program, Healthy Lubbock, the GIA Brain Bank, healthy aging seminars, research seminars, and collaborations and scholarships...
2015: Journal of Alzheimer's Disease: JAD
Fernanda Vieira Ribeiro, Marcio Zaffalon Casati
No abstract text is available yet for this article.
September 2015: Journal of Evidence-based Dental Practice
Grant D Stewart, Fiach C O'Mahony, Alexander Laird, Lel Eory, Alexander L R Lubbock, Alan Mackay, Jyoti Nanda, Marie O'Donnell, Peter Mullen, S Alan McNeill, Antony C P Riddick, Daniel Berney, Axel Bex, Michael Aitchison, Ian M Overton, David J Harrison, Thomas Powles
PURPOSE: The aim of this study was to investigate the effect of VEGF-targeted therapy (sunitinib) on molecular intratumoral heterogeneity (ITH) in metastatic clear cell renal cancer (mccRCC). EXPERIMENTAL DESIGN: Multiple tumor samples (n = 187 samples) were taken from the primary renal tumors of patients with mccRCC who were sunitinib treated (n = 23, SuMR clinical trial) or untreated (n = 23, SCOTRRCC study). ITH of pathologic grade, DNA (aCGH), mRNA (Illumina Beadarray) and candidate proteins (reverse phase protein array) were evaluated using unsupervised and supervised analyses (driver mutations, hypoxia, and stromal-related genes)...
September 15, 2015: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Kerry J Welsh, Yu Bai
A 58-year-old Hispanic man under treatment for a gangrenous toe was found to have chronic microcytic anemia and a positive sickle cell screen. High-performance liquid chromatography and isoelectric focusing electrophoresis showed that the patient is double heterozygous for hemoglobin S and hemoglobin Fannin-Lubbock. The patient does not have any manifestations of a sickling disorder. Capillary hemoglobin electrophoresis initially misclassified this unusual combination of hemoglobin variants.
2015: Annals of Clinical and Laboratory Science
Marie Bugarel, Henk C den Bakker, Kendra K Nightingale, Dayna M Brichta-Harhay, Thomas S Edrington, Guy H Loneragan
Salmonella enterica is principally a foodborne pathogen that shows considerable serovar diversity. In this report, we present two draft genome sequences of Salmonella enterica subsp. enterica serovar Lubbock, a novel serovar.
2015: Genome Announcements
Sanaz Shafian, Stephan J Maas
Variations in soil moisture strongly affect surface energy balances, regional runoff, land erosion and vegetation productivity (i.e., potential crop yield). Hence, the estimation of soil moisture is very valuable in the social, economic, humanitarian (food security) and environmental segments of society. Extensive efforts to exploit the potential of remotely sensed observations to help quantify this complex variable are ongoing. This study aims at developing a new index, the Thermal Ground cover Moisture Index (TGMI), for estimating soil moisture content...
2015: Sensors
Dolores Buscemi, Erwin Argueta, Kenneth Nugent
Case report publications introduce new information into the current body of medical information and provide trainees with an opportunity to develop skills that enhance patient care. However, opportunities for publication are limited because journals often have other editorial priorities and some journals do not want to publish articles that might decrease their impact factors. Using PubMed and Google Scholar, we identified the case report articles published by our residents who completed training between 2008 and 2013...
October 2014: Proceedings of the Baylor University Medical Center
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