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https://www.readbyqxmd.com/read/29145132/effect-of-evaporative-weathering-and-oil-sediment-interactions-on-the-fate-and-behavior-of-diluted-bitumen-in-marine-environments-part-1-spill-related-properties-oil-buoyancy-and-oil-particulate-aggregates-characterization
#1
Yujuan Hua, Fatemeh S Mirnaghi, Zeyu Yang, Bruce P Hollebone, Carl E Brown
The fate and behavior of diluted bitumen spilled in marine conditions has recently become a topic of much interest, yet, only limited knowledge is available. One of the major issues of a diluted bitumen spill on water is whether the product will sink, especially when suspended sediment is present in the water column. This study demonstrated how weathering processes influenced the key spill-related properties of a diluted bitumen product (Cold Lake Blend-Winter), and how interaction of diluted bitumen with sediment affected its tendency to float or sink in water...
October 28, 2017: Chemosphere
https://www.readbyqxmd.com/read/29144557/penile-warty-mucoepidermoid-carcinoma-with-features-of-stratified-mucin-producing-intraepithelial-lesion-and-invasive-stratified-mucin-producing-carcinoma
#2
Kenji Yorita, Naoto Kuroda, Takushi Naroda, Masato Tamura, Chisato Ohe, Mukul Divatia, Mahul B Amin, Antonio L Cubilla, Dimitry V Kazakov, Ondrej Hes, Michael Michal, Michal Michal
AIMS: Stratified mucin-producing intraepithelial lesion (SMILE) and invasive stratified mucin-producing carcinoma (ISMC) are recently described cervical and penile lesions. We report an unusual case of mixed variant of penile squamous cell carcinomas with warty, usual and mucoepidermoid SMILE/ISMC features. METHODS AND RESULTS: A 62-year-old Japanese man had a glans penis lesion of one and a half years duration, suggesting malignancy. Partial penectomy and left inguinal lymphadenectomy were performed...
November 16, 2017: Histopathology
https://www.readbyqxmd.com/read/29144548/anti-m%C3%A3-llerian-hormone-measurement-for-the-diagnosis-of-polycystic-ovary-syndrome
#3
Thozhukat Sathyapalan, Ahmed Al-Qaissi, Eric S Kilpatrick, Soha R Dargham, Stephen L Atkin
OBJECTIVE: Anti-Müllerian hormone (AMH) is derived from the small antral follicles and an elevated level has been suggested to add value to the Rotterdam criteria for the diagnosis of PCOS in cases of diagnostic uncertainty. Therefore, the role of AMH in the classical phenotype of PCOS was defined within a Caucasian population. DESIGN: This was a cross sectional study. PATIENTS: 65 women without PCOS and 110 women with PCOS fulfilling all 3 diagnostic Rotterdam criteria...
November 16, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29144132/large-piezoelectric-effect-in-a-lead-free-molecular-ferroelectric-thin-film
#4
Wei-Qiang Liao, Yuan-Yuan Tang, Peng-Fei Li, Yu-Meng You, Ren-Gen Xiong
Piezoelectric materials have been widely used in various applications, such as high-voltage sources, actuators, sensors, motors, fre-quency standard, vibration reducer, and so on. In the past decades, lead zirconate titanate (PZT) binary ferroelectric ceramics have dominated the commercial piezoelectric market due to their excellent properties near the morphotropic phase boundary (MPB), although they contain more than 60% toxic lead element. Here, we report a lead-free and one-composition molecular ferroelectric trimethylbromomethylammonium tribromomanganese (ΙΙ) (TMBM-MnBr3) with a large piezoelectric coefficient d33 of 112 pC/N along polar axis, comparable with those of typically one-composition piezoceramics such as BaTiO3 along polar axis [001] (~90 pC/N) and much greater than those of most known molecular ferroelectrics (almost below 40 pC/N)...
November 16, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29143952/-the-effect-of-mood-stabilising-drugs-on-cytokine-levels-in-bipolar-disorder-a-systematic-review
#5
S Van Den Ameele, L van Diermen, W Staels, V Coppens, G Dumont, B Sabbe, M Morrens
Veranderde cytokineconcentraties bij personen met een bipolaire stoornis ten opzichte van controle-personen suggereren een rol van het immuunsysteem in de pathofysiologie van bipolaire stoornis. Farmacotherapie is een belangrijke verstorende factor in klinisch onderzoek naar cytokineconcentraties.<br/> DOEL: Evalueren van cytokineconcentraties bij medicatievrije patiënten met een bipolaire stoornis en van het effect van stemmingsstabiliserende geneesmiddelen op deze concentraties.<br/> METHODE: We doorzochten systematisch PubMed en Embase naar klinische studies die cytokineconcentraties bij medicatievrije patiënten met een bipolaire stoornis beschrijven of het effect van een individueel stemmingsstabiliserend geneesmiddel op deze concentraties evalueren...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/29143466/tuberculosis-serosurveillance-and-management-practices-of-captive-african-elephants-loxodonta-africana-in-the-kavango-zambezi-transfrontier-conservation-area
#6
L E Rosen, T G Hanyire, J Dawson, C M Foggin, A L Michel, K P Huyvaert, M A Miller, F J Olea-Popelka
Transfrontier conservation areas represent an international effort to encourage conservation and sustainable development. Their success faces a number of challenges, including disease management in wildlife, livestock and humans. Tuberculosis (TB) affects humans and a multitude of non-human animal species and is of particular concern in sub-Saharan Africa. The Kavango-Zambezi Transfrontier Conservation Area encompasses five countries, including Zimbabwe, and is home to the largest contiguous population of free-ranging elephants in Africa...
November 16, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29142396/antioxidant-and-cholinesterase-inhibitory-activities-of-ethyl-acetate-extract-of-terminalia-chebula-cell-free-in-vitro-and-in-silico-studies
#7
Mohamed Asik Rajmohamed, Suganthy Natarajan, Premkumar Palanisamy, Akbarsha Mohammad Abdulkader, Archunan Govindaraju
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder clinically characterized by memory loss and impaired cognitive function. Cholinergic enzyme deficiency and oxidative stress are the two major factors implicated in the pathogenesis of AD. The symptomatic treatment, as of now, is the use of cholinesterase inhibitors toward cholinergic "downturn." Therefore, there is a search for compounds that will be useful in focused therapies. There has been suggestion that Terminalia chebula fruit would be a potential source...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29141648/polymorphisms-at-microrna-binding-sites-of-ara-c-and-anthracyclines-metabolic-pathway-genes-are-associated-with-outcome-of-acute-myeloid-leukemia-patients
#8
Hai-Xia Cao, Chao-Feng Miao, Liang Yan, Ping Tang, Li-Rong Zhang, Ling Sun
BACKGROUND: Gene polymorphisms at microRNA-binding sites (poly-miRTS) may affect gene transcription and expression through miRNA regulation, which is associated with cancer susceptibility, sensitivity to chemotherapy and prognosis. This study investigated the association between poly-miRTS of Ara-C/anthracycline metabolic pathways genes and the outcome of acute myeloid leukemia (AML) in Chinese patients after Ara-C-based chemotherapy. METHODS: A total of 17 poly-miRTS were selected from the SNPinfo Web Server and genotyped in 206 Chinese Han non-FAB-M3 AML patients using the SEQUENOM Mass-ARRAY system...
November 15, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29141150/all-dielectric-dual-color-pixel-with-subwavelength-resolution
#9
Yusuke Nagasaki, Masafumi Suzuki, Junichi Takahara
An all-dielectric optical antenna supporting Mie resonances enables light confinement below the free-space diffraction limit. The Mie scattering wavelengths of the antenna depend on the structural geometry, which allows the antennas to be used for colored imprint images. However, there is still room for improving the spatial resolution, and new polarization-dependent color functionalities are highly desirable for realizing a wider color tuning range. Here, we show all-dielectric color printing by means of dual-color pixels with a subwavelength-scale resolution...
November 15, 2017: Nano Letters
https://www.readbyqxmd.com/read/29140658/killing-u-s-slowly-curing-the-epidemic-rise-of-cancer-drug-prices
#10
Emily K White
In August 2015, more than 110 U.S. oncologists published an article detailing the deleterious effects of rising cancer drugs prices and calling for numerous reforms to our prescription drug system. These prices are the result of decades of political maneuvering; they reflect the way our country has chosen to pay for healthcare, to foster and reward innovation, and to promote a national free market system. While these choices have resulted in immense profits for pharmaceutical companies—and subsidized the development of prescription drugs globally—they have also left many cancer patients unable to afford their medications...
2017: Food and Drug Law Journal
https://www.readbyqxmd.com/read/29140330/all-optimized-integrated-rf-photonic-notch-filter
#11
Yang Liu, Jason Hotten, Amol Choudhary, Benjamin J Eggleton, David Marpaung
We report a silicon nitride chip-based radio-frequency photonic notch filter with an unprecedented performance including an RF gain of 8 dB, a record-low noise figure of 15.6 dB, and a spurious-free dynamic range of 116  dB·Hz(2/3), with a stop band rejection of 50 dB. This level of performance is achieved by using on-chip resonators' unique phase responses, and thorough optimizations of the photonic link. These record results will potentially stimulate future implementations of integrated microwave photonic subsystems for real-world applications...
November 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29140281/non-contact-sensor-for-long-term-continuous-vital-signs-monitoring-a-review-on-intelligent-phased-array-doppler-sensor-design
#12
REVIEW
Travis Hall, Donald Y C Lie, Tam Q Nguyen, Jill C Mayeda, Paul E Lie, Jerry Lopez, Ron E Banister
It has been the dream of many scientists and engineers to realize a non-contact remote sensing system that can perform continuous, accurate and long-term monitoring of human vital signs as we have seen in many Sci-Fi movies. Having an intelligible sensor system that can measure and record key vital signs (such as heart rates and respiration rates) remotely and continuously without touching the patients, for example, can be an invaluable tool for physicians who need to make rapid life-and-death decisions. Such a sensor system can also effectively help physicians and patients making better informed decisions when patients' long-term vital signs data is available...
November 15, 2017: Sensors
https://www.readbyqxmd.com/read/29137971/clearance-of-schistosome-parasites-by-resistant-genotypes-at-a-single-genomic-region-in-biomphalaria-glabrata-snails-involves-cellular-components-of-the-hemolymph
#13
Euan R O Allan, Benjamin Gourbal, Camila B Dores, Anais Portet, Christopher J Bayne, Michael S Blouin
Schistosomiasis is one of the most detrimental neglected tropical diseases. Controlling the spread of this parasitic illness requires effective sanitation, access to chemotherapeutic drugs, and control over populations of the freshwater snails, such as Biomphalaria glabrata, that are essential intermediate hosts for schistosomes. Effectively controlling this disease, while minimizing ecological implications of such control, will require an extensive understanding of the immunological interactions between schistosomes and their molluscan intermediate hosts...
November 11, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/29137699/determination-of-sulfite-in-food-by-liquid-chromatography-tandem-mass-spectrometry-collaborative-study
#14
Katherine S Carlos, Lowri S de Jager
Sulfites are added to a wide range of food and beverage products to prevent browning or oxidation. Although most of the population do not experience side effects from consuming sulfites, a small subset has been shown to experience an "allergic-like" response. For this reason, the U.S. Food and Drug Administration requires that sulfites be labeled on all products that contain more than 10 mg/kg (parts per million) sulfur dioxide. The current regulatory method, optimized Monier-Williams (OMW) Official Method 990...
November 1, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29136453/randomized-phase-iii-trial-of-adjuvant-therapy-with-locoregional-interferon-beta-versus-surgery-alone-in-stage-ii-iii-cutaneous-melanoma-japan-clinical-oncology-group-study-jcog1309-j-feron
#15
Kenjiro Namikawa, Arata Tsutsumida, Tomonori Mizutani, Taro Shibata, Tatsuya Takenouchi, Shusuke Yoshikawa, Yoshio Kiyohara, Hiroshi Uchi, Masutaka Furue, Dai Ogata, Tetsuya Tsuchida, Naoya Yamazaki
The Dermatologic Oncology Group of Japan Clinical Oncology Group has started a randomized phase III trial to confirm the superiority of adjuvant therapy with locoregional interferon beta in overall survival over surgery alone for patients with pathological stage II/III cutaneous melanoma (JCOG1309). Patients in the interferon beta arm receive intra- or subcutaneous injections of interferon beta directly into the surgical site at a flat dose of 3 million units once per day. Treatment is repeated for 10 consecutive days every 8 weeks for a total of 3 courses during the induction phase, then 1-day injection every 4 weeks for 2...
July 1, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29136187/a-phase-iii-trial-of-a-single-early-intravesical-instillation-of-pirarubicin-to-prevent-bladder-recurrence-after-radical-nephroureterectomy-for-upper-tract-urothelial-carcinoma-jcog1403-utuc-thp-phase-iii
#16
Kenichi Miyamoto, Akihiro Ito, Masashi Wakabayashi, Junko Eba, Yoichi Arai, Hiroyuki Nishiyama, Mikio Sugimoto, Ryo Yamashita, Yoshiyuki Kakehi
Observation is the current standard for managing cases of Stage 0a-III upper tract urothelial carcinoma after radical nephroureterectomy. A randomized Phase III trial commenced in Japan during October 2016. The trial is designed to investigate the superiority of a single early intravesical instillation of pirarubicin, compared with observation, in terms of relapse-free survival after radical nephroureterectomy for Stage 0a-III upper tract urothelial carcinoma. During a 5-year period, 310 patients will be recruited from 43 Japanese institutions...
November 9, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29135583/effect-of-immediate-initiation-of-antiretroviral-treatment-on-the-risk-of-acquired-hiv-drug-resistance
#17
Sara Lodi, Huldrych F Günthard, David Dunn, Federico Garcia, Roger Logan, Sophie Jose, Heiner C Bucher, Alexandra U Scherrer, Marie-Paule Schneider, Matthias Egger, Tracy R Glass, Peter Reiss, Ard van Sighem, T Sonia Boender, Andrew N Phillips, Kholoud Porter, David Hawkins, Santiago Moreno, Susana Monge, Dimitrios Paraskevis, Metallidis Simeon, Georgia Vourli, Caroline Sabin, Miguel A Hernán
OBJECTIVE: We estimated and compared the risk of clinically identified acquired drug resistance under i) immediate initiation (the currently recommended ART initiation strategy), ii) initiation with CD4 < 500, and iii) initiation with CD4 < 350 cells/mm. DESIGN: Cohort study based on routinely collected data from the HIV-CAUSAL Collaboration. METHODS: For each individual, baseline was the earliest time when all eligibility criteria (ART-naïve, AIDS-free, and others) were met after 1999...
November 10, 2017: AIDS
https://www.readbyqxmd.com/read/29135219/room-temperature-and-solution-processable-cu-doped-nickel-oxide-nanoparticles-for-efficient-hole-transport-layers-of-flexible-large-area-perovskite-solar-cells
#18
Qiqi He, Kai Yao, Xiaofeng Wang, Xuefeng Xia, Shifeng Leng, Fan Li
Flexible perovskite solar cells (PeSCs) using plastic substrates have become one of the most attractive points in the field of thin film solar cells. Low-temperature and solution-processable nanoparticles enable the fabrication of semiconductor thin films in a simple and low cost approach to function as charge-selective layers in flexible PeSCs. Here, we synthesized phase-pure p-type Cu-doped NiOx nanoparticles (NPs) with good electrical properties, which can be processed to smooth, pinhole-free and efficient hole transport layers (HTLs) with large-area uniformity over a wide range of film thickness using the room-temperature solution-processing technique...
November 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29135216/interfacial-molecular-packing-determines-exciton-dynamics-in-molecular-heterostructures-the-case-of-pentacene-perfluoropentacene
#19
Andre Rinn, Tobias Breuer, Julia Wiegand, Michael Beck, Jens Hübner, Robin C Döring, Michael Oestreich, Wolfram Heimbrodt, Gregor Witte, Sangam Chatterjee
The great majority of electronic and optoelectronic devices depend on interfaces between p-type and n-type semiconductors. Finding matching donor-acceptor systems in molecular semiconductors remains a challenging endeavor since structurally compatible molecules may not necessarily be suitable with respect to their optical and electronic properties and the large exciton binding energy in these materials may favor bound electron-hole pairs rather than free carriers or charge-transfer at an interface. Regardless, interfacial charge-transfer exciton states are commonly considered as an intermediate step to achieve exciton dissociation...
November 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29135062/organocatalyzed-photo-controlled-radical-polymerization-of-semi-fluorinated-meth-acrylates-driven-by-visible-light
#20
Mao Chen, Honghong Gong, Yucheng Zhao, Xianwang Shen, Jun Lin
Fluorinated polymers are important materials that are widely used in many areas. Herein, we report the development of a metal-free photo-controlled radical polymerization of semi-fluorinated (meth)acrylates with a new visible light absorbing organocatalyst. This method allows the production of a variety of semi-fluorinated polymers with narrow molar weight distributions from semi-fluorinated trithiocarbonates or perfluoroalkyl iodide. The high performance of "ON/OFF" control and chain extension experiments further demonstrate the utility and reliability of this method...
November 14, 2017: Angewandte Chemie
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