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Pediatric seizure

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https://www.readbyqxmd.com/read/29210926/hospital-readmissions-after-pediatric-trauma
#1
Aline B Maddux, Peter E DeWitt, Peter M Mourani, Tellen D Bennett
OBJECTIVES: To determine the rate, etiology, and timing of unplanned and planned hospital readmissions and to identify risk factors for unplanned readmission in children who survive a hospitalization for trauma. DESIGN: Multicenter retrospective cohort study of a probabilistically linked dataset from the National Trauma Data Bank and the Pediatric Health Information System database, 2007-2012. SETTING: Twenty-nine U.S. children's hospitals...
November 28, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29204024/behavioral-problems-and-intelligence-quotient-changes-in-pediatric-epilepsy-a-case-control-study
#2
Shyama Choudhary, N Niranjan, Satyendra Khichar, Pramod K Berwal, Abhijeet Singh Barath
Background: Epilepsy is the most common chronic neurological disease and has neurological impairment as an important comorbidity. Objective: To find behavioral problems and intelligence quotient (IQ) changes associated with epilepsy and to know the association of variables such as frequency, type of seizures, and duration of disease with cognitive impairment. Materials and Methods: A descriptive cross sectional study, consisting of 50 cases (patients of epilepsy) and 50 controls (other patients of same socioeconomic status) was conducted at S...
October 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29201855/posterior-reversible-encephalopathy-syndrome-after-head-trauma-surgery-in-pediatric-patient-without-any-underlying-disease
#3
Jae Eon Yoon, Cheol Young Lee, Hyun Woo Kim
Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder characterized by signs of posterior cerebral edema upon radiographic examination. A 16-year-old girl was involved in motorcycle accident and depressed frontal fracture was presented. She had generalized seizures 3 days after dural repair and fracture reduction. Signal changes was noted on both parietal lobes in the magnetic resonance images and it was completely resolved in 3 months follow-up. We would like to present the case that demonstrated PRES related hypertension after head trauma surgery for cerebrospinal fluid leakage in pediatric patient without any underlying disease...
October 2017: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29201280/a-network-approach-to-examining-injury-severity-in-pediatric-tbi
#4
Emily L Dennis, Faisal Rashid, Neda Jahanshad, Talin Babikian, Richard Mink, Christopher Babbitt, Jeffrey Johnson, Christopher C Giza, Robert F Asarnow, Paul M Thompson
Traumatic brain injury (TBI) is the leading cause of death and disability in children, and can lead to long lasting functional impairment. Many factors influence outcome, but imaging studies examining effects of individual variables are limited by sample size. Roughly 20-40% of hospitalized TBI patients experience seizures, but not all of these patients go on to develop a recurrent seizure disorder. Here we examined differences in structural network connectivity in pediatric patients who had sustained a moderate-severe TBI (msTBI)...
2017: Proceedings of the IEEE International Symposium on Biomedical Imaging: from Nano to Macro
https://www.readbyqxmd.com/read/29201120/long-term-video-eeg-monitoring-findings-in-children-and-adolescents-with-intractable-epilepsy
#5
Yasaman Ghazavi, Ebrahim Asayesh Zarchi, Taher Taheri, Mahdi Safiabadi, Elham Rahimian, Susan Amirsalari
Objective: Long Term Video-EEG Monitoring (LTM) may give us important information in the preoperative assessment of these patients. We performed this study for the first time in pediatric age group in Iran. Materials and Methods: In this cross-sectional study, 43 children between 4 to 18 yr, with intractable epilepsy referred to Shefa Neuroscience Research Center, Tehran, Iranfrom2007-2012, were enrolled to study in order to evaluate their long-term video EEG findings...
2017: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/29197666/surgical-outcome-and-predictive-factors-of-epilepsy-surgery-in-pediatric-isolated-focal-cortical-dysplasia
#6
Sun Ah Choi, Soo Yeon Kim, Hyuna Kim, Woo Joong Kim, Hunmin Kim, Hee Hwang, Ji Eun Choi, Byung Chan Lim, Jong-Hee Chae, Sangjoon Chong, Ji Yeoun Lee, Ji Hoon Phi, Seung-Ki Kim, Kyu-Chang Wang, Ki Joong Kim
OBJECTIVE: Focal cortical dysplasia (FCD) is a common cause of medically intractable epilepsy in children. Epilepsy surgery has been a valuable treatment option to achieve seizure freedom in these intractable epilepsy patients. We aimed to present long-term surgical outcome, in relation to pathological severity, and to assess predictive factors of epilepsy surgery in pediatric isolated FCD. METHODS: We retrospectively analyzed the data of 58 children and adolescents, with FCD International League Against Epilepsy (ILAE) task force classification types I and II, who underwent resective epilepsy surgery and were followed for at least 2 years after surgery...
November 27, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29191650/cortical-language-areas-and-plasticity-in-pediatric-patients-with-epilepsy-a-review
#7
REVIEW
Naomi Chou, Sandra Serafini, Carrie R Muh
Chronic injury to the brain from seizure activity is associated with decreased language skills in pediatric patients, as measured on neuropsychological tests for language function and academic achievement. This makes the study of language in patients with epilepsy clinically necessary. Functional magnetic resonance imaging and direct electrical cortical stimulation have been used to evaluate aspects of cortical language processing in healthy adults and in adults with epilepsy or other neurological insults. Results of these studies help to locate cortical language areas that are involved with modality-specific language processing (visual naming, auditory naming, sentence-completion, and repetition) and the neuroplasticity of language areas in the setting of neurological injury and reorganization...
October 12, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29186598/favorable-long-term-functional-outcomes-and-safety-of-auditory-brainstem-implants-in-nontumor-patients
#8
Na Young Jung, Minsoo Kim, Won Seok Chang, Hyun Ho Jung, Jae Young Choi, Jin Woo Chang
BACKGROUND: Auditory brainstem implants (ABIs) were designed to restore hearing in deaf patients with auditory tumors or those unable to receive cochlear implants. Although ABIs may help some patients, their long-term outcomes have been rarely studied. OBJECTIVE: To assess the long-term benefits and safety of ABIs in nontumor patients with sensorineural hearing loss (SNHL). METHODS: We retrospectively reviewed the histories of 15 deaf patients (8 females, 7 males; mean age, 15...
December 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29184380/ketogenic-diet-in-super-refractory-status-epilepticus
#9
COMMENT
Garnett Smith, Craig A Press
Researchers from the Children's National Health System in Washington, D.C. studied the feasibility, rate of complications, and effect on seizures of initiating the Ketogenic Diet (KD) in pediatric patients with Super-Refractory Status Epilepticus (SRSE).
November 2017: Pediatric Neurology Briefs
https://www.readbyqxmd.com/read/29182970/time-to-continuous-electroencephalogram-in-repeated-admissions-to-the-pediatric-intensive-care-unit
#10
Iván Sánchez Fernández, Arnold J Sansevere, Marina Gaínza-Lein, Ersida Buraniqi, Robert C Tasker, Tobias Loddenkemper
PURPOSE: Describe timing from intensive care unit (ICU) admission to initiation of continuous electroencephalogram (cEEG) in repeated ICU admissions. METHOD: We performed a retrospective observational study in pediatric patients who underwent repeated ICU admissions with cEEG from 2011 to 2013. The main outcome measure was time from ICU admission to cEEG. RESULTS: There were 41 patients (54% males) with at least 2 ICU admissions with cEEG (median (p25-p75) age at first admission: 3...
November 21, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29178011/pyridoxine-dependent-epilepsies-an-observational-study-on-clinical-diagnostic-therapeutic-and-prognostic-features-in-a-pediatric-cohort
#11
Raffaele Falsaperla, Maria Stella Vari, Irene Toldo, Alessandra Murgia, Stefano Sartori, Marilena Vecchi, Agnese Suppiej, Alberto Burlina, Mario Mastrangelo, Vincenzo Leuzzi, Valentina Marchiani, Paola De Liso, Giuseppe Capovilla, Pasquale Striano, Giovanna Vitaliti
The aim of our study was to describe the clinical, electroencephalogram, molecular findings and the diagnostic and therapeutic flow-chart of children with pyridoxine-dependent epilepsies (PDEs). We performed a retrospective observational study on children with PDEs, diagnosed and followed-up in Italian Pediatric Departments. In each centre, the authors collected data from a cohort of children admitted for intractable seizures, responsive to pyridoxine administration and resistant to other anticonvulsant therapies...
November 25, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29171923/clinical-and-genetic-findings-in-children-with-cns-arteriovenous-fistulas
#12
Guillaume Saliou, Mélanie Eyries, Marta Iacobucci, Jean François Knebel, Marie-Christine Waill, Florence Coulet, Augustin Ozanne, Florent Soubrier
OBJECTIVE: To assess the spectrum of genetic anomalies in a cohort of children presenting at least one cerebral or spinal pial arteriovenous fistula (AVF), and to describe their clinical characteristics. METHODS: From 1988 to 2016, all consecutive patients with at least one cerebral or spinal pial AVF were screened for genetic disease. All patients under the age of 18 years were included. Symptoms associated with AVF were recorded: heart failure, neurologic deficit/seizure, hemorrhage...
November 24, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29167084/parent-s-experiences-of-their-children-suffering-febrile-seizures
#13
Emma Westin, Märta Sund Levander
PURPOSE: To explore parents' experiences of their child suffering febrile seizures. DESIGN AND METHOD: Seven mothers and four fathers with experience of one or several febrile seizures in their children were interviewed. A qualitative content analysis with an inductive approach was performed. RESULT: Five themes emerged; emotional experiences, in terms of anxiety and fear, and need for control, need for support, need for acknowledgement and need for comfort...
November 11, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29159426/an-initial-cost-effectiveness-analysis-of-intraoperative-magnetic-resonance-imaging-imri-in-pediatric-epilepsy-surgery
#14
Matthew F Sacino, Sean S Huang, Robert F Keating, William D Gaillard, Chima O Oluigbo
PURPOSE: Previous studies have illustrated the clinical utility of the addition of intraoperative magnetic resonance imaging (iMRI) to conventional microsurgical resection. While iMRI requires initial capital cost investment, long-term reduction in costly follow-up management and reoperation costs may prove economically efficacious. The objective of this study is to investigate the cost-effectiveness of the addition of iMRI utilization versus conventional microsurgical techniques in focal cortical dysplasia (FCD) resection in pediatric patients with medically refractory epilepsy...
November 20, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29157502/pediatric-psychogenic-nonepileptic-seizures-a-concise-review
#15
REVIEW
Julia L Doss, Sigita Plioplys
Psychogenic nonepileptic seizures is a complicated biopsychosocial disorder with significant morbidity and high cost in children's social, emotional, family, and academic functioning as well as health care service utilization. Misdiagnosis and diagnostic delay, resulting from both lack of access to approved standards for diagnosing and service providers comfortable with diagnosing and treating this disorder, impact prognosis. Treatment in close proximity to symptom onset is thought to provide the best chance for remission...
January 2018: Child and Adolescent Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/29149805/observational-cohort-study-safety-outcomes-in-children-using-proton-pump-inhibitors-or-histamine-2-receptor-antagonists
#16
Eline Houben, Saga Johansson, Péter Nagy, Fernie J A Penning-van Beest, Ernst J Kuipers, Ron M C Herings
OBJECTIVE: Acid suppression with histamine-2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs) is recommended for children with persistent gastroesophageal reflux disease symptoms. In this retrospective, observational postauthorization study, we aimed to assess and compare safety outcomes in pediatric first-time users of esomeprazole, other PPIs, or H2RAs. METHODS: Data on children (aged 0-18 years) first dispensed esomeprazole, other PPIs, or H2RAs between September 2008 and August 2011 were obtained from the Dutch PHARMO Database Network...
November 17, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29141311/-study-on-mosaicism-of-scn1a-gene-mutation-in-parents-of-children-with-dravet-syndrome
#17
A J Liu, X X Yang, X J Xu, Q X Wu, X J Tian, X L Yang, X R Wu, L P Wei, Y H Zhang
Objective: To investigate the clinical phenotypes and the mutant allele proportion of parents with SCN1A gene mutation mosaicism of Dravet syndrome (DS) children, thus to provide guidance for family reproduction and prenatal diagnosis. Method: The clinical data and peripheral blood DNA samples of DS patients with a SCN1A gene mutation proved by Sanger sequencing were collected prospectively from February 2005 to November 2016 in Department of Pediatrics, Peking University First Hospital. The same mutation was searched in parents and other available relatives...
November 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29140931/hemispheric-cerebral-oximetry-monitoring-during-pediatric-seizure-activity-in-a-pediatric-emergency-department
#18
Thomas J Abramo, Shane McKinney, James Moore, Richard Jacobs, Gregory Albert, Mark Meredith, Nicholas Hobart Porter, Elizabeth Storm, Errin Willis, Cruz Velasco Gonzalez, Hailey Hargrave, Brad Schneider, Gergory Sharp
BACKGROUND: Sustained neuronal activity during seizures causes cellular perturbations, alterations in cerebral physiology, and potentially neurological injury, a neurological emergency. With variable clinical manifestations of seizures, frequent failure of seizure recognition by providers in pediatric and developmentally challenged patients can increase seizure complications. Neuroresuscitation should include rapid cerebral physiology assessment for increased seizure recognition and optimal neurological outcomes...
November 15, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29135901/clinical-factors-associated-with-pediatric-brain-neoplasms-versus-primary-headache-a-case-control-analysis
#19
David C Sheridan, Bethany Waites, Bradley Lezak, Robert J Coryell, Kellie J Nazemi, Amber L Lin, Rongwei Fu, Matthew L Hansen
OBJECTIVE: Pediatric headaches are a common presentation to emergency departments accounting for almost half a million annual visits. Providers are left with the difficult task of deciding who has a secondary headache etiology that warrants neuroimaging. METHODS: We conducted a retrospective case-control study. Patients from a pediatric neuro-oncology clinic database with brain cancer and a headache at presentation were identified as cases. Controls were patients from 2 local pediatric tertiary care emergency departments with a final diagnosis of headache after negative neuroimaging...
November 14, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29128331/risk-factors-for-epilepsy-recurrence-after-revascularization-in-pediatric-patients-with-moyamoya-disease
#20
Yonggang Ma, Meng Zhao, Qian Zhang, Xingju Liu, Dong Zhang, Shuo Wang, Yan Zhang, Maogui Li, Jizong Zhao
OBJECTIVE: We aimed to explore the risk factors of seizure recurrence and the optimal surgical procedure for epileptic pediatric patients with moyamoya disease (MMD). METHODS: We reviewed 696 consecutive patients with MMD admitted to our hospital from 2009 to 2015. Pediatric patients with MMD who had seizures before revascularization were identified. We summarized the characteristics of seizures in pediatric patients with MMD and analyzed the predictive factors of recurrent seizure events...
November 8, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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