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JOURNAL ARTICLE
Ragaey A Eid, Marwa O Elgendy, Ahmed M Sayed, Abdelrahman M Abdallah, Hayam Ma Mostafa, Ahmed Mohammed M Elsisi, Ahmed M Hamed, Marwa Abdallah Shaker
INTRODUCTION: At the beginning in July 2023, there has been a significant increase in daily hospital admissions attributed to the new variant of COVID-19. Aim of this study is to explore the clinical benefits and outcomes of using linezolid in the management of pneumonic COVID-19 patients. METHODOLOGY: The study included 230 patients with SARS-CoV-2 infection confirmed by RT-PCR. Group 1: 118 patients were managed with Linazolid alongside steroids. Group 2: (control group) patients treated according to the Protocol for Egyptian COVID-19 management outlines and WHO guidelines (112 patients)...
March 31, 2024: Journal of Infection in Developing Countries
#22
JOURNAL ARTICLE
Mireille Razafindrakoto, François Roubaud, Marta Reis Castilho, Valeria Pero, João Saboia
Brazil counts among the countries the hardest hit by the Covid-19 pandemic. A great deal has been said about the negative role played by President Bolsonaro's denialism, but relatively few studies have attempted to measure precisely what impact it actually had on the pandemic. Our paper conducts econometric estimates based on observational data at municipal level to quantitatively assess the 'Bolsonaro effect' over time from March 2020 to December 2022. To our knowledge, this paper presents the most comprehensive investigation of Bolsonaro's influence in the spread of the pandemic from two angles: considering Covid-19 mortality and two key transmission mitigation channels (social distancing and vaccination); and exploring the full pandemic cycle (2020-2022) and its dynamics over time...
2024: PloS One
#23
JOURNAL ARTICLE
Abdeta Muktar Ahmed, Mohamed Abdilahi Ahmed, Mohammed Hassen Ahmed
BACKGROUND: About 287,000 mothers lost their lives due to pregnancy and delivery in 2020 worldwide. Birth preparedness and complication readiness (BPCR) is an approach used to utilize the timely use of skilled maternal and neonatal services. Preparing mothers for childbirth and against its dangers has great importance in reducing maternal mortality. Little is known about BPCR and influencing factors in Hargeisa town, Somaliland. OBJECTIVE: To assess the level of BPCR and its associated factors among recently delivered women in Hargeisa...
2024: PloS One
#24
JOURNAL ARTICLE
Cihat Erdogan, Ilknur Suer, Murat Kaya, Sukru Ozturk, Nizamettin Aydin, Zeyneb Kurt
Breast cancer (BC) is the most common cancer among women with high morbidity and mortality. Therefore, new research is still needed for biomarker detection. GSE101124 and GSE182471 datasets were obtained from the Gene Expression Omnibus (GEO) database to evaluate differentially expressed circular RNAs (circRNAs). The Cancer Genome Atlas (TCGA) and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) databases were used to identify the significantly dysregulated microRNAs (miRNAs) and genes considering the Prediction Analysis of Microarray classification (PAM50)...
2024: PloS One
#25
JOURNAL ARTICLE
Ashwin A Pillai, Mai Badr, Xingchen Mai, Anum Dilip, Jennifer Bell
Cardiogenic shock (CS) occurs infrequently in pregnancy and has a high mortality rate. Medical treatment options are few, with limited evidence of efficacy. Temporary mechanical circulatory supports (tMCS) may play a key role in addressing this therapeutic lacuna. We report successfully managing second-trimester CS using an Impella 5.5 micro-axial pump. Our patient presented in the second-trimester with CS. Hemodynamic parameters indicated biventricular dysfunction (low cardiac index, low pulmonary artery pulsatility index)...
April 19, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
#26
JOURNAL ARTICLE
Na Li, Shanxiu Jin, Jingran Wu, Hongjuan Ji, Cheng Du, Bona Liu
BACKGROUND: To examine the trends in morbidity and mortality among ovarian cancer patients with liver metastases, and investigate the impact of different treatments on both overall survival (OS) and cancer-specific survival (CSS). METHODS: 2,925 ovarian cancer patients with liver metastases from Surveillance, Epidemiology, and End Results 2010-2019 were included. The primary endpoint was considered as OS and CSS. We conducted trend analysis of the incidence, OS and CSS rates of liver metastases in ovarian cancer...
2024: PloS One
#27
REVIEW
Dina Yehia, Clarus Leung, Don D Sin
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) accounts for 545 million people living with chronic respiratory disorders and is the third leading cause of morbidity and mortality around the world. COPD is a progressive disease, characterized by episodes of acute worsening of symptoms such as cough, dyspnea, and sputum production. AREAS COVERED: Airway inflammation is a prominent feature of COPD. Chronic airway inflammation results in airway structural remodeling and emphysema...
April 18, 2024: Expert Review of Molecular Diagnostics
#28
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
#29
JOURNAL ARTICLE
Kirsten Evans, Michele Casper, Linda Schieb, David DeLara, Adam S Vaughan
No abstract text is available yet for this article.
April 18, 2024: Preventing Chronic Disease
#30
JOURNAL ARTICLE
Jennifer P Collins, Samuel J Crowe, Ismael R Ortega-Sanchez, Lynn Bahta, Doug Campos-Outcalt, Jamie Loehr, Rebecca L Morgan, Katherine A Poehling, Lucy A McNamara
Meningococcal disease is a life-threatening invasive infection caused by Neisseria meningitidis. Two quadrivalent (serogroups A, C, W, and Y) meningococcal conjugate vaccines (MenACWY) (MenACWY-CRM [Menveo, GSK] and MenACWY-TT [MenQuadfi, Sanofi Pasteur]) and two serogroup B meningococcal vaccines (MenB) (MenB-4C [Bexsero, GSK] and MenB-FHbp [Trumenba, Pfizer Inc.]), are licensed and available in the United States and have been recommended by CDC's Advisory Committee on Immunization Practices (ACIP). On October 20, 2023, the Food and Drug Administration approved the use of a pentavalent meningococcal vaccine (MenACWY-TT/MenB-FHbp [Penbraya, Pfizer Inc...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
#31
JOURNAL ARTICLE
Roberto Santa Cruz, Amelia Matesa, Antonella Gómez, Juan Nadur, Fernando Pagano, Daniel Prieto, Oswald Bolaños, Beatriz Solis, Sara Yusta, Edilzar González-Velásquez, Elisa Estenssoro, Alexandre Cavalcanti
OBJECTIVES: Mortality due to acute respiratory distress syndrome (ARDS) is a major global health problem. Knowledge of epidemiological data on ARDS is crucial to design management, treatment strategies, and optimize resources. There is ample data regarding mortality of ARDS from high-income countries; in this review, we evaluated mortality due to ARDS in Latin America. DATA SOURCES: We searched in PubMed, Cochrane Central Register of Controlled Trials, Web of Science, and Latin American and Caribbean Health Science Literature databases from 1967 to March 2023...
April 18, 2024: Critical Care Medicine
#32
JOURNAL ARTICLE
Ambarish Vaidyanathan, Abigail Gates, Claudia Brown, Emily Prezzato, Aaron Bernstein
Unprecedented heat waves can affect all persons, but some are more sensitive to the effects of heat, including children and adults with underlying health conditions, pregnant women, and outdoor workers. Many regions of the United States experienced record-breaking high temperatures in 2023, with populations exposed to extremely high temperatures for prolonged periods. CDC examined emergency department (ED) visits associated with heat-related illness (HRI) from the National Syndromic Surveillance Program and compared daily HRI ED visit rates during the warm-season months (May-September) of 2023 with those during 2018-2022...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
#33
JOURNAL ARTICLE
Laura D Zambrano, Margaret M Newhams, Regina M Simeone, Amanda B Payne, Michael Wu, Amber O Orzel-Lockwood, Natasha B Halasa, Jemima M Calixte, Pia S Pannaraj, Kanokporn Mongkolrattanothai, Julie A Boom, Leila C Sahni, Satoshi Kamidani, Kathleen Chiotos, Melissa A Cameron, Aline B Maddux, Katherine Irby, Jennifer E Schuster, Elizabeth H Mack, Austin Biggs, Bria M Coates, Kelly N Michelson, Katherine E Bline, Ryan A Nofziger, Hillary Crandall, Charlotte V Hobbs, Shira J Gertz, Sabrina M Heidemann, Tamara T Bradford, Tracie C Walker, Stephanie P Schwartz, Mary Allen Staat, Samina S Bhumbra, Janet R Hume, Michele Kong, Melissa S Stockwell, Thomas J Connors, Melissa L Cullimore, Heidi R Flori, Emily R Levy, Natalie Z Cvijanovich, Matt S Zinter, Mia Maamari, Cindy Bowens, Danielle M Zerr, Judith A Guzman-Cottrill, Ivan Gonzalez, Angela P Campbell, Adrienne G Randolph
Pediatric COVID-19 vaccination is effective in preventing COVID-19-related hospitalization, but duration of protection of the original monovalent vaccine during SARS-CoV-2 Omicron predominance merits evaluation, particularly given low coverage with updated COVID-19 vaccines. During December 19, 2021-October 29, 2023, the Overcoming COVID-19 Network evaluated vaccine effectiveness (VE) of ≥2 original monovalent COVID-19 mRNA vaccine doses against COVID-19-related hospitalization and critical illness among U...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
#34
JOURNAL ARTICLE
David Franklin, Kira Barbre, Theresa A Rowe, Hannah E Reses, Jason Massey, Lu Meng, Philip Dollard, Heather Dubendris, Molly Stillions, Lindsay Robinson, Jacques W Clerville, Kara Jacobs Slifka, Andrea Benin, Jeneita M Bell
Nursing home residents are at increased risk for developing severe COVID-19. Nursing homes report weekly facility-level data on SARS-CoV-2 infections, COVID-19-associated hospitalizations, and COVID-19 vaccination coverage among residents to CDC's National Healthcare Safety Network. This analysis describes rates of incident SARS-CoV-2 infection, rates of incident COVID-19-associated hospitalization, and COVID-19 vaccination coverage during October 16, 2023-February 11, 2024. Weekly rates of SARS-CoV-2 infection ranged from 61...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
#35
JOURNAL ARTICLE
Rachael R Kirkbride, Galit Aviram, Benedikt H Heidinger, Yuval Liberman, Aurelija Libauske, Rokas Liubauskas, Daniela M Tridente, Alexander Brook, Dominique C DaBreo, Antonio C Monteiro Filho, Brett J Carroll, Jason D Matos, Ian C McCormick, Warren J Manning, Diana E Litmanovich
PURPOSE: Small left atrial (LA) volume was recently reported to be one of the best predictors of acute pulmonary embolism (PE)-related adverse events (AE). There is currently no data available regarding the impact that body surface area (BSA)-indexing of atrial measurements has on the association with PE-related adverse events. Our aim is to assess the impact of indexing atrial measurements to BSA on the association between computed tomography (CT) atrial measurements and AE. MATERIALS AND METHODS: Retrospective study (IRB: 2015P000425)...
April 18, 2024: Journal of Thoracic Imaging
#36
JOURNAL ARTICLE
Shan Ling, Laifa Yan, Rongsong Mao, Jizhou Li, Haoran Xi, Fei Wang, Xiaolin Li, Min He
Congenital heart disease (CHD) is the most frequent birth defect and a leading cause of infant mortality, emphasizing the crucial need for its early diagnosis. Ultrasound is the primary imaging modality for prenatal CHD screening. As a complement to the four-chamber view, the three-vessel view (3VV) plays a vital role in detecting anomalies in the great vessels. However, the interpretation of fetal cardiac ultrasound images is subjective and relies heavily on operator experience, leading to variability in CHD detection rates, particularly in resource-constrained regions...
April 18, 2024: IEEE Journal of Biomedical and Health Informatics
#37
JOURNAL ARTICLE
Wenao Ma, Cheng Chen, Yuqi Gong, Nga Yan Chan, Meirui Jiang, Calvin Hoi-Kwan Mak, Jill M Abrigo, Qi Dou
Aneurysmal subarachnoid hemorrhage is a serious medical emergency of brain that has high mortality and poor prognosis. Treatment effect estimation is of high clinical significance to support the treatment decision-making for aneurysmal subarachnoid hemorrhage. However, most existing studies on treatment decision support of this disease are unable to simultaneously compare the potential outcomes of different treatments for a patient. Furthermore, these studies fail to harmoniously integrate the imaging data with non-imaging clinical data, both of which are significant in clinical scenarios...
April 18, 2024: IEEE Transactions on Medical Imaging
#38
JOURNAL ARTICLE
Manal Mohamed Adel, Nagwa Yoseif Salem, Hany Mohamed Hussein
The Nano-formulation of citronella essential oil ( Cymbopogon nardus (L.) and their mixtures of three adjuvants (Provecta®, Top film®, and PEG600-dioleate) were studied to enhance physico-chemical properties of the Nano-formulation and improve the insecticidal effect against Spodoptera littoralis (Boisd). Characterisation of physicochemical properties of Nano-formulation was studied by calculating droplet size, polydispersity index (PDI), and Zeta-potential parameters. The results showed that the Solid Lipid Nanoparticles (SLNs) mixtures of three adjuvant mixtures had more toxic activity and stability than the Nano-formulation alone...
April 18, 2024: Natural Product Research
#39
JOURNAL ARTICLE
Eline M J Lammers, Josée M Zijlstra, Valesca P Retèl, Berthe M P Aleman, Flora E van Leeuwen, Annelies Nijdam
BACKGROUND: Hodgkin lymphoma (HL) occurs at young ages, with the highest incidence between 20 and 40 years. While cure rates have improved to 80%-90% over the past decades, survivors of HL are at substantial risk of late treatment-related complications, such as cardiovascular diseases, breast cancer, severe infections, and hypothyroidism. To reduce morbidity and mortality from late treatment effects, the Dutch Better care after lymphoma, Evaluation of long-term Treatment Effects and screening Recommendations (BETER) consortium developed a survivorship care program for 5-year survivors of HL that includes risk-based screening for and treatment of (risk factors for) late adverse events...
April 18, 2024: JMIR Research Protocols
#40
JOURNAL ARTICLE
Marco V Usai, Efthymios Beropoulis, Stefano Fazzini, Konstantinos Avranas, Yousef Khatatba, Apostolos Pitoulias, Gergana T Taneva, Martin J Austermann, Konstantinos P Donas
BACKGROUND: The aim of this study was to evaluate the early results of the CE-marked standardized device combination consisting of Endurant and the Radiant chimney graft (En-ChEVAR) for the treatment of juxtarenal aortic aneurysms. METHODS: We analyzed multicentric non-industry sponsored case series evaluating the EnChEVAR technique for patients treated between December 2022 and February 2024. Clinical, perioperative procedure-related and radiological data were collected...
April 18, 2024: Journal of Cardiovascular Surgery
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