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https://www.readbyqxmd.com/read/29031616/factors-affecting-the-selection-of-an-inhaler-device-for-copd-and-the-ideal-device-for-different-patient-profiles-results-of-epoca-delphi-consensus
#1
Marc Miravitlles, Juan José Soler-Cataluña, Bernardino Alcázar, José Luis Viejo, Francisco García-Río
BACKGROUND: This study aimed to identify the relevant factors for the choice of an inhaler device by physicians and the selection of the most important characteristics of a device according to different characteristics of patients with COPD. METHOD: In this two-round Delphi survey, 96 Spanish COPD-expert pulmonologists completed an internet-based, self-administered questionnaire, which consisted of a first part with 19 items related to the prioritization of the drug or the device, the experience, ability and preference of the patient, and the experience and preferences of the healthcare professional...
October 12, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29022232/a-case-of-fatal-perimyocarditis-due-to-a-rare-disease
#2
Stefanie Plenzig, Sara Heinbuch, Hannelore Held, Marcel A Verhoff, Constantin Lux
Although myocarditis is caused by viral infections in about 50% of cases in European countries, various other causative agents are known. We report the case of a 51-year-old man who died several months after being diagnosed with asthma by his general practitioner. This diagnosis had been confirmed by a pulmonologist approximately 6 weeks before the man's death. To rule out the possibility of medical malpractice the prosecuting authority ordered a forensic autopsy. At autopsy macroscopic indicators for perimyocarditis and pneumonia were found...
October 11, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29017958/higher-priced-older-pharmaceuticals-how-should-we-respond
#3
Richard S Irwin, Scott Manaker, Mark L Metersky, Robert P Baughman, Tunde Otulana, Steven E Weinberger, Andrew J Sussman, Norine A McGrath
We and our patients have been aware of the high cost of medications in the United States for decades. However, we are recently witnessing a relatively new phenomenon: exponential price increases for some older pharmaceuticals that have been available for years. To assist practitioners in how to respond to the issue of higher priced pharmaceuticals, an interprofessional session was developed and held at CHEST 2016 in Los Angeles. The session proceedings and a few updates are presented here to summarize what pulmonologists, a sarcoidosis expert, a retired executive of a medical society, pharmaceutical company, pharmacy, and an ethicist advise that we do about the problem...
October 7, 2017: Chest
https://www.readbyqxmd.com/read/28985364/concomitant-pulmonologist-and-primary-care-for-chronic-obstructive-pulmonary-disease-a-population-study
#4
Andrea S Gershon, Erin M Macdonald, Jin Luo, Peter C Austin, Samir Gupta, Khalil Sivjee, Ross Upshur, Shawn D Aaron
Background: Pulmonologists provide quality care, however, their number is not adequate to take care of all the chronic obstructive pulmonary disease (COPD) needs of the population and their services come with a cost. Their optimal role should be defined, ideally based on evidence, to ensure that their abilities are applied most efficiently where needed. Objective: To determine if concomitant pulmonologist and primary care physician care after COPD hospital or emergency department discharge was associated with better health outcomes than primary care services alone...
July 7, 2017: Family Practice
https://www.readbyqxmd.com/read/28978238/ototoxicity-monitoring-through-the-eyes-of-the-treating-physician-perspectives-from-pulmonology-and-medical-oncology
#5
Angela C Garinis, Alexandra Cornell, Gopal Allada, Kevin P Fennelly, Ronald J Maggiore, Dawn Konrad-Martin
OBJECTIVES: Integrating audiological management into the care pathways of clinical specialties that prescribe ototoxic medications for essential, often life-preserving medical care that is critical for early hearing loss identification and remediation. Research shows that successful implementation of a new health service or intervention requires alignment of goals among provider groups, institutional leadership and patients. Thoughtful consideration of the physician's viewpoints about ototoxicity and its implications for treatment planning is, therefore, important for the implementation and enduring success of an ototoxicity monitoring programme (OMP)...
October 5, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28972833/management-of-patients-with-stage-i-lung-cancer
#6
Jeffrey A Bogart, Jason Wallen
The treatment of stage I non-small-cell lung cancer has advanced markedly over the past century. The transition from therapeutic nihilism with ensured mortality to radical surgery with pneumonectomy to rational oncologic-based resection has resulted in dramatically improved outcomes and reduced morbidity. The superiority of anatomic resection with lobectomy over sublobar resection for fit patients with stage I disease, where more than one half of all patients should expect to be cured, is backed by level 1 evidence...
February 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28967732/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-under-conscious-sedation-with-meperidine-and-midazolam
#7
Lorenzo Agostini, Nicola Facciolongo, Mirco Lusuardi, Eleonora Casalini, Carla Galeone, Luciano Lasagni, Luigi Zucchi
Endobronchial Ultrasound guided transbronchial needle aspiration (EBUS-TBNA) is usually performed under general anesthesia or deep sedation with drugs such as Propofol that, at least in Italy, can be administered only by an anesthesiologist. Aim of the study was to assess conscious sedation feasibility, safety and tolerability using Meperidine and Midazolam as administered by Pulmonologist and relevant impact on the efficiency of the sampling procedures.All patients undergoing EBUS-TBNA from February 2013 to July 2014 were examined retrospectively...
July 18, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28956954/hiv-related-chronic-lung-disease-in-adolescents-are-we-prepared-for-the-future
#8
Pierre Goussard, Robert P Gie
Chronic lung diseases (CLD) are the most chronic disease occurring in adolescents living with human immunodeficiency virus (ALHIV). In ALHIV who received antiretroviral therapy (ART) late in childhood, bronchiectasis, bronchiolitis obliterans and interstitial pneumonitis are common. In adolescents who received ART early in life the spectrum of CLD has changed with asthma and chronic obstructive pulmonary disease being common. Areas covered: The aim of this paper was to review CLD in ALHIV. We conducted a literature review of electronic databases focusing on CLD that were common prior to the introduction of ART (1996-2004), the present situation where ART is widely available (2005 to 2016), and articles which aided us speculating on the impact of HIV-related CLD in adolescents transitioning to adult HIV-clinics...
September 28, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28947013/prevalence-and-management-of-copd-and-heart-failure-comorbidity-in-the-general-practitioner-setting
#9
Pietro Pirina, Marco Martinetti, Claudia Spada, Elisabetta Zinellu, Rosanna Pes, Efisio Chessa, Alessandro Giuseppe Fois, Marc Miravitlles
BACKGROUND: COPD frequently coexists with HF with which shares several risk factors. A greater collaboration is required between cardiologists and pulmonologists to better identify and manage concurrent HF and COPD. This observational, retrospective study provides new data regarding the management of these patients. METHODS: from the Health Search Database which collects information generated by the routine activity of general practitioners, we selected 803 patients suffering from COPD or HF alone or combined analyzing similarities and differences regarding risk factors, diagnostic workup and therapeutic approaches...
October 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28942886/who-treats-lung-cancer-results-from-a-global-survey
#10
Takefumi Komiya, Christine B Mackay, Prabhakar Chalise
BACKGROUND: In most Western nations, the medical oncologist plays a significant role in the administration of systemic therapy for lung cancer. In Japan however, treatment for lung cancer has historically been provided by pulmonologists and thoracic surgeons. A comparison of the management of advanced disease between Japan and other nations has not been described. METHODS: An online, self-administered, international survey was sent to 3907 active members of the American Society of Clinical Oncology...
September 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/28933940/an-assessment-of-primary-care-and-pulmonary-provider-perspectives-on-lung-cancer-screening
#11
Matthew Triplette, Erin K Kross, Blake A Mann, Joann G Elmore, Christopher G Slatore, Shahida Shahrir, Perrin E Romine, Paul D Frederick, Kristina Crothers
RATIONALE: Lung cancer screening (LCS) has a mortality benefit to high-risk smokers, but implementation remains suboptimal. Providers represent the key entry point to screening, and an understanding of provider perspectives on lung cancer screening is necessary to improve referral and overall implementation. OBJECTIVES: The objective of this study was to understand knowledge, beliefs, attitudes, barriers, and facilitators to screening in a diverse group of referring pulmonologists and primary care providers...
September 21, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28928841/lung-cancer-requires-multidisciplinary-treatment-to-improve-patient-survival-a-case-report
#12
Aldo Pezzuto, Fabrizio Terzo, Maria Laura Graziani, Alberto Ricci, Pierdonato Bruno, Salvatore Mariotta
The present study reports two cases of lung cancer with the involvement of the pleura. The diagnosis of adenocarcinoma with epidermal growth factor receptor (EGFR) mutation was made following repeated thoracentesis with cytology of pleural fluid and thoracoscopy with pleural biopsies. Talc pleurodesis was successfully performed in both cases subsequent to diagnosis. Following talc pleurodesis, the first patient (62 years old; male; non-smoker) underwent 3 cycles of cisplatin/vinorelbine chemotherapy, with a poor response...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28914743/effectiveness-of-bone-suppression-imaging-in-the-detection-of-lung-nodules-on-chest-radiographs-relevance-to-anatomic-location-and-observer-s-experience
#13
Tomohiro Miyoshi, Junji Yoshida, Nao Aramaki, Yuki Matsumura, Keiju Aokage, Tomoyuki Hishida, Tsuyoshi Kobayashi, Shinichi Tsubura, Shinsuke Katsuhara, Satoshi Kasai, Yasuhiko Sasano, Kanji Nagai, Masahiro Tsuboi
OBJECTIVE: To evaluate the effectiveness of bone suppression imaging (BSI) software in lung-nodule detection on chest radiographs (CXRs) in relation to nodule location and observer's experience. MATERIALS AND METHODS: The CXRs of 80 patients, of which 40 had a lung nodule (8 to 30 mm in diameter) and 40 did not have any nodules, were interpreted by 20 observers comprising of 7 pulmonologists with >10 years of experience and 13 pulmonology residents. Each patient's image was sequentially read, first using the standard CXR and thereafter with the BSI software...
September 13, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28906274/flexible-bronchoscope-use-by-pulmonologists-in-collaboration-with-gastroenterologists-for-placement-of-percutaneous-endoscopic-gastrostomy-via-transnasal-route-in-patients-with-head-and-neck-cancer-a-10-year-experience-in-a-single-cancer-institution
#14
Paulo J L Mota, Jorge Dionísio, José Duro da Costa, Sandra Faias
This study was conducted with the aim of evaluating a 10-year experience in the Pulmonology Department of a cancer center for percutaneous endoscopic gastrostomy through transnasal route (TN-PEG) in patients with head and neck cancer whose oral access is precluded. This study was a retrospective analysis of 40 consecutive head and neck cancer patients referred for PEG placement, between 2005 and 2014, using a transnasal route because of the impossibility of intubation through the oral cavity. Demographics, outcome of TN-PEG procedure, indications for bronchoscopic approach (prophylactic/palliative), clinical need for bronchoscopy (trismus, oropharyngeal obstruction), location of cancer, complications, and overall survival were reviewed...
September 12, 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28891722/requirements-strengths-and-weaknesses-of-inhaler-devices-for-copd-patients-from-the-expert-prescribers-point-of-view-results-of-the-epoca-delphi-consensus
#15
Francisco García-Río, Juan J Soler-Cataluña, Bernardino Alcazar, José L Viejo, Marc Miravitlles
The study aimed to assess the preferences of expert physicians about the requirements for inhalation devices for patients with chronic obstructive pulmonary disease (COPD) and to identify the most relevant advantages and disadvantages to their prescription. In a two-round Delphi survey, 96 Spanish COPD-expert pulmonologists completed an internet-based questionnaire to evaluate the degree of importance of the characteristics of the inhaler devices in their choice for COPD. The requirements needed for use in COPD were that the device permits a high pulmonary deposit of the drug, allowed its dispensation at low inspiratory flows, did not require hand-mouth coordination, generated an exact and reproducible dose, its operation was easy to teach, provided the perception of a correct inhalation, had an intuitive use mechanism and security mechanisms to prevent overdosing and generates a reduced oropharyngeal deposit (very good consensus)...
September 11, 2017: COPD
https://www.readbyqxmd.com/read/28891479/dexamethasone-vs-placebo-in-children-having-pneumonia-with-pleural-effusion-pediatric%C3%A2-pulmonologist-s-viewpoint
#16
Varinder Singh
No abstract text is available yet for this article.
August 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28886099/serial-quantiferon-tb-gold-testing-in-patients-with-psoriasis-treated-with-ustekinumab
#17
Chuan-Yu Hsiao, Hsien-Yi Chiu, Ting-Shun Wang, Tsen-Fang Tsai
BACKGROUND: There is increasing concern about the risk of latent tuberculosis infection (LTBI) reactivation during the use of biologics for psoriasis. Although ustekinumab had been documented with low risk of tuberculosis, the long-term follow-up of LTBI as determined by QuantiFERON-TB Gold (QFT-G) testing in patients treated with ustekinumab is limited. OBJECTIVES: This study aims to use serial QFT-G testing as a screening method for detecting LTBI in patients with psoriasis from an intermediate tuberculosis burden country...
2017: PloS One
https://www.readbyqxmd.com/read/28884381/development-of-a-computer-aided-differential-diagnosis-system-to-distinguish-between-usual-interstitial-pneumonia-and-non-specific-interstitial-pneumonia-using-texture-and-shape-based-hierarchical-classifiers-on-hrct-images
#18
SangHoon Jun, BeomHee Park, Joon Beom Seo, SangMin Lee, Namkug Kim
A computer-aided differential diagnosis (CADD) system that distinguishes between usual interstitial pneumonia (UIP) and non-specific interstitial pneumonia (NSIP) using high-resolution computed tomography (HRCT) images was developed, and its results compared against the decision of a radiologist. Six local interstitial lung disease patterns in the images were determined, and 900 typical regions of interest were marked by an experienced radiologist. A support vector machine classifier was used to train and label the regions of interest of the lung parenchyma based on the texture and shape characteristics...
September 7, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28883469/characteristics-of-newly-diagnosed-copd-patients-treated-with-triple-inhaled-therapy-by-general-practitioners-a-real-world-italian-study
#19
Fabiano Di Marco, Pierachille Santus, Silvia Terraneo, Elena Peruzzi, Elisa Muscianisi, Claudio Ripellino, Valeria Pegoraro
Factors predicting prescriptions of triple therapy were investigated in a large group of general practitioners in Italy. In the population treated by identified general practitioners, a cohort of newly diagnosed chronic obstructive pulmonary disease patients was extracted from IMS Health Longitudinal Database during the period 2010-2013. From the diagnosis, 1-year follow-up was evaluated. Thirty-two thousand forty-six newly diagnosed chronic obstructive pulmonary disease patients were evaluated (57.7% male, mean age 67 years)...
September 7, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28881352/current-practice-of-airway-stenting-in-the-adult-population-in-europe-a-survey-of-the-european-association-of-bronchology-and-interventional-pulmonology-eabip
#20
Hervé Dutau, David Breen, Antonio Bugalho, Levent Dalar, Johannes Daniels, Christophe Dooms, Ralf Eberhardt, Lars Ek, Milena Encheva, Michel Febvre, Martin Hackl, Sirje Marran, Zsolt Papai-Szekely, Michael Perch, Mihovil Roglic, Antoni Rosell, Ales Rozman, Pallav L Shah, Marioara Simon, Artur Szlubowski, Grigoris Stratakos, Arve Sundset, Toomas Uibu, Christophe Von Garnier, Bojan Zaric, Marija Zdraveska, Lina Zuccatosta, Darijo Bokan, Syed Arshad Husain, Semra Bilaceroglu, Paola Gasche-Soccal, Stefano Gasparini, Felix J F Herth, Muhammed Munavvar
BACKGROUND: Airway stenting (AS) commenced in Europe circa 1987 with the first placement of a dedicated silicone airway stent. Subsequently, over the last 3 decades, AS was spread throughout Europe, using different insertion techniques and different types of stents. OBJECTIVES: This study is an international survey conducted by the European Association of Bronchology and Interventional Pulmonology (EABIP) focusing on AS practice within 26 European countries. METHODS: A questionnaire was sent to all EABIP National Delegates in February 2015...
September 8, 2017: Respiration; International Review of Thoracic Diseases
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