keyword
https://read.qxmd.com/read/38633019/road2h-development-and-evaluation-of-an-open-source-explainable-artificial-intelligence-approach-for-managing-co-morbidity-and-clinical-guidelines
#1
JOURNAL ARTICLE
Jesús Domínguez, Denys Prociuk, Branko Marović, Kristijonas Čyras, Oana Cocarascu, Francis Ruiz, Ella Mi, Emma Mi, Christian Ramtale, Antonio Rago, Ara Darzi, Francesca Toni, Vasa Curcin, Brendan Delaney
INTRODUCTION: Clinical decision support (CDS) systems (CDSSs) that integrate clinical guidelines need to reflect real-world co-morbidity. In patient-specific clinical contexts, transparent recommendations that allow for contraindications and other conflicts arising from co-morbidity are a requirement. In this work, we develop and evaluate a non-proprietary, standards-based approach to the deployment of computable guidelines with explainable argumentation, integrated with a commercial electronic health record (EHR) system in Serbia, a middle-income country in West Balkans...
April 2024: Learning Health Systems
https://read.qxmd.com/read/38628297/pediatric-pulmonary-milestones-2-0-development-lessons-learned-and-future-directions
#2
JOURNAL ARTICLE
Laura E Chiel, Erica L Stevens, Lara C Bishay, Melanie S Collins, Jennifer A Rama, Laura Edgar, Sydney McLean, Ida Haynes, Hiren Muzumdar, Pnina Weiss, Debra Boyer, B Louise Giles
Pediatric pulmonology fellowship training programs are required by the Accreditation Council for Graduate Medical Education to report Pediatric Subspecialty Milestones biannually to track fellow progress. However, several issues, such as lack of subspecialty-specific context and ambiguous language, have raised concerns about their validity and applicability to use for fellow assessment and curriculum development. In this Perspective, we briefly share the process of the Pediatric Pulmonology Milestones 2.0 Work Group in creating new specialty-specific Milestones and tailoring information on the Harmonized Milestones to pediatric pulmonologists, with the goal of improving the Milestones' utility for stakeholders, including pulmonology fellows, faculty, program directors, and accrediting bodies...
March 2024: ATS scholar
https://read.qxmd.com/read/38617786/beyond-diagnosis-a-narrative-review-of-the-evolving-therapeutic-role-of-medical-thoracoscopy-in-the-management-of-pleural-diseases
#3
REVIEW
Alberto Fantin, Nadia Castaldo, Michelangelo Schwartzbaum Palou, Giovanni Viterale, Ernesto Crisafulli, Giulia Sartori, Filippo Patrucco, Paolo Vailati, Giuseppe Morana, Federico Mei, Lina Zuccatosta, Vincenzo Patruno
BACKGROUND AND OBJECTIVE: Medical thoracoscopy (MT) is an endoscopic technique performed by interventional pulmonologists with a favorable safety profile and few contraindications, providing diagnostic and therapeutic intervention in a single sitting. This narrative review was designed to summarize the therapeutic role of MT based on the latest results from the available literature. METHODS: Pertinent literature published in English, relative to human studies, between 2010-2022 was searched in Medline/PubMed and Cochrane databases...
March 29, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38606709/-not-available
#4
JOURNAL ARTICLE
Andreas Arnholdt Pedersen, Victor Næstholt Dahl, Ole Hilberg, Anders Løkke, Andreas Fløe
This review focuses on the treatment of nontuberculous pulmonary disease caused by Mycobacterium avium complex and M. abscessus. It covers treatment indications, antibiotic choice, resistance and side effects. Treatment of nontuberculous pulmonary disease is complex, lengthy, and fraught with side effects. Increased attention on this disease is needed in order to alleviate the severe consequences of this growing disease. Cooperation between pulmonologists and infectious disease specialists is needed to ensure uniform treatment, and to account for the heterogeneity seen in patients and mycobacteria alike...
April 1, 2024: Ugeskrift for Laeger
https://read.qxmd.com/read/38606032/mediastinal-and-tracheal-shift-due-to-recurrent-sigmoid-volvulus-a-case-report
#5
Mensur Osman Yasin, Mezgebu Alemneh Assefa, Hirut Tesfahun Alemu, Yohannis Derbew Molla
We hereby present a 70-year-old male Ethiopian farmer who presented with clinical manifestations suggestive of acute large bowel obstruction, which had persisted for 3 days. Over the past 3 years, he has experienced three similar recurring episodes, which were alleviated by decompression using a rectal tube. Upon initial examination, the patient displayed signs of cardiopulmonary distress, although no indications of peritonitis were observed. Further evaluation through plain abdominal and chest X-rays revealed findings consistent with sigmoid volvulus, as well as mediastinal shift, elevated diaphragm, and a right-positioned heart...
2024: SAGE Open Medical Case Reports
https://read.qxmd.com/read/38589116/prevalence-of-tuberculosis-in-homes-for-the-aged-and-orphanages-of-a-district-in-kerala-india
#6
JOURNAL ARTICLE
Zinia T Nujum, Sindhu S, P S Rakesh, Remya G, Anuja U
BACKGROUND: India accounts for one fourth of the TB burden globally. One of the objectives of the National Strategic Plan is to achieve 90% notification rate of all TB cases. Screening of high risk groups is one of the important components towards achieving this objective. Inmates of homes for the aged and orphanages are at higher risk of having TB infection and disease. Hence this study was conducted with the objective of identifying the prevalence of TB among inmates of homes for the aged and orphanages...
April 2024: Indian Journal of Tuberculosis
https://read.qxmd.com/read/38581960/chronic-rhinosinusitis-possibly-associated-with-decreased-lung-function-in-chronic-cough-patients
#7
JOURNAL ARTICLE
Pengfei Zhao, Shin Kariya, Takaya Higaki, Seiichiro Makihara, Toru Rikimaru, Mitsuhiro Okano, Mizuo Ando
OBJECTIVES: The purpose of this study is to investigate the lung function in Chronic Rhinosinusitis (CRS) patients with Chronic Cough (CC). METHODS: A total of 1413 CC patients were retrospectively screened and 109 CRS patients with CC were enrolled. Lung function, Lund-Mackay Computed Tomography (CT) score, smoking status, peripheral blood eosinophil count, and immunoglobulin E concentration in serum samples, and Sino-Nasal Outcome Test were examined. Normal control subjects are also recruited...
March 21, 2024: Brazilian Journal of Otorhinolaryngology
https://read.qxmd.com/read/38576000/discriminative-potential-of-exhaled-breath-condensate-biomarkers-with-respect-to-chronic-obstructive-pulmonary-disease
#8
JOURNAL ARTICLE
Romain Freund, Jean-Jacques Sauvain, Guillaume Suarez, Pascal Wild, Thomas Charreau, Amélie Debatisse, Kirushanthi Sakthithasan, Valérie Jouannique, Jacques A Pralong, Irina Guseva Canu
BACKGROUND: Chronic obstructive pulmonary disease (COPD) affecting 334 million people in the world remains a major cause of morbidity and mortality. Proper diagnosis of COPD is still a challenge and largely solely based on spirometric criteria. We aimed to investigate the potential of nitrosative/oxidative stress and related metabolic biomarkers in exhaled breath condensate (EBC) to discriminate COPD patients. METHODS: Three hundred three participants were randomly selected from a 15,000-transit worker cohort within the Respiratory disease Occupational Biomonitoring Collaborative Project (ROBoCoP)...
April 4, 2024: Journal of Occupational Medicine and Toxicology
https://read.qxmd.com/read/38575832/-diagnosis-and-therapy-of-patients-with-asthma-in-germany-results-of-the-care-study-relevant
#9
JOURNAL ARTICLE
Frederik Trinkmann
BACKGROUND: Diagnostic and therapeutic options for asthma have improved with asthma control and remission being of central importance. The RELEVANT study aimed for a nationwide snapshot of current asthma diagnosis and treatment in general practice and specialty care for identification of further aspects for optimization. METHOD: RELEVANT is a nationwide cross-sectional study using a structured questionnaire. This comprised 14 questions on asthma-related topics covering diagnostics and therapy...
April 2024: MMW Fortschritte der Medizin
https://read.qxmd.com/read/38574348/the-asthma-app-as-a-new-way-to-promote-responsible-short-acting-beta2-agonist-use-in-people-with-asthma-results-of-a-mixed-methods-pilot-study
#10
JOURNAL ARTICLE
Liselot N van den Berg, Cynthia Hallensleben, Lisa Ae Vlug, Niels H Chavannes, Anke Versluis
BACKGROUND: Approximately 262 million people worldwide are affected by asthma, and the overuse of reliever medication-specifically, short-acting beta2-agonist (SABA) overuse-is common. This can lead to adverse health effects. A smartphone app, the Asthma app, was developed via a participatory design to help patients gain more insight into their SABA use through monitoring and psychoeducation. OBJECTIVE: This pilot study aims to evaluate the feasibility and usability of the app...
April 4, 2024: JMIR Human Factors
https://read.qxmd.com/read/38567566/characteristics-of-chest-high-resolution-computed-tomography-in-patients-with-anti-aminoacyl-trna-synthetase-antibody-positive-interstitial-lung-disease
#11
JOURNAL ARTICLE
Masato Mima, Seidai Sato, Takayoshi Shinya, Nobuhito Naito, Takatoshi Shoji, Saki Harada, Ryoko Suzue, Kojin Murakami, Kazuya Koyama, Yasuhiko Nishioka
BACKGROUND AND AIM: Anti-aminoacyl-tRNA synthetase (ARS) antibodies form a condition called Antisynthetase syndrome (ASSD). While interstitial lung disease (ILD) is a particularly frequent manifestation of ASSD and is closely associated with morbidity and mortality, few studies have been conducted on its characteristics on high-resolution computed tomography (HRCT). In this study, we clarified the HRCT findings in patients with anti-ARS antibody-positive ILD (ARS-ILD).  Methods: The HRCT findings at the time of the ILD diagnosis in 24 ARS-ILD patients were retrospectively evaluated by 2 pulmonologists and one radiologist...
March 26, 2024: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://read.qxmd.com/read/38558404/practices-and-perspectives-on-advanced-diagnostic-and-interventional-bronchoscopy-among-pediatric-pulmonologists-in-the-united-states
#12
JOURNAL ARTICLE
A Corcoran, D Shore, R P Boesch, M Chopra, S Das, D DiBardino, S Goldfarb, A Haas, E Hysinger, P Phinizy, A Vicencio, J Toth, J Piccione
INTRODUCTION: Advanced diagnostic bronchoscopy includes endobronchial ultrasound (EBUS) guided transbronchial lung and lymph node biopsies, CT navigation and robotic bronchoscopy. Interventional bronchoscopy refers to procedures performed for therapeutic purposes such as balloon dilation of the airway, tissue debulking, cryotherapy, removal of foreign bodies and insertion of endobronchial valves [1]. For adult patients, these procedures are standard of care [2, 3]. Despite a lack of formalized training, there are numerous case reports and case series describing the use of advanced diagnostic and interventional bronchoscopy techniques in children...
April 1, 2024: Pediatric Pulmonology
https://read.qxmd.com/read/38553722/patients-evaluation-of-aftercare-following-hospitalization-for-covid-19-satisfaction-and-unmet-needs
#13
JOURNAL ARTICLE
Julia C Berentschot, Willemijn A de Ridder, L Martine Bek, Majanka H Heijenbrok-Kal, Gert-Jan Braunstahl, Sylvia C Remerie, Yvonne Stuip, Gerard M Ribbers, Joachim G J V Aerts, Erwin Ista, Merel E Hellemons, Rita J G van den Berg-Emons
BACKGROUND: Patient experiences with COVID-19 aftercare remain largely unknown. We evaluated COVID-19 aftercare from a patient perspective one year after hospitalization, assessing satisfaction and its associated factors, and unmet needs. METHODS: The Satisfaction with COVID-19 Aftercare Questionnaire (SCAQ) was developed as part of a multicenter prospective cohort study and administered one year after hospital discharge. The SCAQ assesses (1) patient satisfaction, comprising information provision, rehabilitation, follow-up by hospitals and general practitioners (GPs), the most important aftercare topics, and overall satisfaction, and (2) unmet needs...
March 29, 2024: Respiratory Research
https://read.qxmd.com/read/38552456/an-elderly-woman-with-birt-hogg-dub%C3%A3-syndrome-having-multiple-pulmonary-cysts-mimicking-lymphangioleiomyomatosis
#14
Yasuhito Sekimoto, Isao Yamawaki, Chikako Iwabuchi, Koichi Nishino, Kazuhisa Takahashi, Kuniaki Seyama
The characteristics of the pulmonary cysts on the high-resolution computed tomography (HRCT) chest images are an important diagnostic clue to distinguish among cystic lung diseases. The diagnostic accuracy of HRCT was reported to be as high as 90% by experienced pulmonologists and radiologists. Herein, we report the case of an elderly woman with Birt-Hogg-Dubé syndrome (BHDS) whose HRCT images displayed lymphangioleiomyomatosis-like features of the pulmonary cysts, rendering it difficult for us to diagnose BHDS...
March 28, 2024: Respiratory Investigation
https://read.qxmd.com/read/38545994/ats-core-curriculum-2023-pediatric-pulmonary-medicine-respiratory-disorders-in-infants
#15
REVIEW
Carmen Leon-Astudillo, Fei J Dy, Michael Y McCown, Iris A Perez, Divya Chhabra, Manvi Bansal, Melissa A Maloney, Mariana Bedoya, Dima Ezmigna, Douglas Bush, Caroline U A Okorie, Jane E Gross
The American Thoracic Society Core Curriculum updates clinicians annually in pediatric pulmonary disease. This is a summary of the Pediatric Pulmonary Medicine Core Curriculum presented at the 2023 American Thoracic Society International Conference. The respiratory disorders of infancy discussed in this year's review include: the care of the patient with bronchopulmonary dysplasia in the neonatal intensive care unit, clinical phenotypes and comorbidities; diffuse lung disease; pulmonary hypertension; central and obstructive sleep apnea...
March 28, 2024: Pediatric Pulmonology
https://read.qxmd.com/read/38539116/optimizing-care-for-children-with-difficult-to-treat-and-severe-asthma-through-specialist-paediatric-asthma-centres-expert-practical-experience-and-advice
#16
JOURNAL ARTICLE
M W Pijnenburg, S Rubak, H O Skjerven, S Verhulst, V Elenius, C Hugen, O Jauhola, C Kempeneers, E Melén, T Reier Nilsen, N W Rutjes, M Ruotsalainen, H Schaballie, A M Zwitserloot, M Proesmans, M J Mäkelä
Severe asthma in children carries an unacceptable treatment burden, yet its rarity means clinical experience in treating it is limited, even among specialists. Practical guidance is needed to support clinical decision-making to optimize treatment for children with this condition.This modified Delphi convened 16 paediatric pulmonologists and allergologists from northern Europe, all experienced in treating children with severe asthma. Informed by interviews with stakeholders involved in the care of children with severe asthma (including paediatricians, nurses and carers), and an analysis of European guidelines, the experts built a consensus focused on the gaps in existing guidance...
March 27, 2024: BMC Pediatrics
https://read.qxmd.com/read/38536981/relative-incidence-of-interstitial-lung-diseases-in-brazil
#17
JOURNAL ARTICLE
Simone Lobo Krupok Matias, Carlos Alberto de Castro Pereira, Maria Raquel Soares, Flávia Castro Velasco Fernandes, Maria Auxiliadora Carmo Moreira, Fernanda Maciel de Aguiar Baptista, Tarciane Aline Prata, Gediel Cordeiro Junior, Eliane Viana Mancuzo
OBJECTIVE: To assess the relative frequency of incident cases of interstitial lung diseases (ILDs) in Brazil. METHODS: This was a retrospective survey of new cases of ILD in six referral centers between January of 2013 and January of 2020. The diagnosis of ILD followed the criteria suggested by international bodies or was made through multidisciplinary discussion (MDD). The condition was characterized as unclassifiable ILD when there was no specific final diagnosis following MDD or when there was disagreement between clinical, radiological, or histological data...
2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38534990/safety-and-diagnostic-yield-of-medical-pleuroscopy-mp-performed-under-balanced-analgosedation-by-a-pneumological-team-compared-to-video-assisted-thoracic-surgery-vats-a-retrospective-controlled-real-life-study-torapo
#18
JOURNAL ARTICLE
Valentino Allocca, Luca Guidelli, Angela Galgano, Lucia Benedetti, Roberto Fabbroni, Andrea Bianco, Piero Paladini, Raffaele Scala
INTRODUCTION: Medical pleuroscopy (MP) is an invasive technique that provides access to the pleural space with a rigid or semi-rigid work instrument, allowing for visualization and the obtaining of bioptic pleural samples. Using pulmonologist-based analgosedation to perform pleuroscopy is still debated for safety reasons. The aim of this real-life study is to demonstrate the safety and diagnostic yield of MP performed under balanced analgosedation by a pulmonologist team with expertise in the management of critically ill patients in the respiratory intensive care unit (RICU) and interventional pulmonology unit as compared to video-assisted thoracic surgery (VATS) performed by a thoracic surgeon team under anesthesiologist-based analgosedation...
March 7, 2024: Diagnostics
https://read.qxmd.com/read/38514242/-the-role-of-the-pulmonologist-in-the-therapeutic-strategy-for-stage-i-bronchopulmonary-cancers
#19
EDITORIAL
V Gounant, A Khalil, G Zalcman
No abstract text is available yet for this article.
March 2024: Revue des Maladies Respiratoires
https://read.qxmd.com/read/38509351/the-interplay-between-rheumatic-diseases-and-pulmonary-health
#20
REVIEW
Yuliya Fedorchenko, Olena Zimba, Roman Yatsyshyn, Bohdana Doskaliuk, Liubomyr Zaiats, Mykhailo Fedorchenko
Patients with rheumatic diseases (RDs) are prone to a number of comorbidities, particularly those affecting the respiratory system due to inflammatory and autoimmune mechanisms. Rheumatoid arthritis (RA), systemic sclerosis (SSc), and inflammatory idiopathic myopathies (IIMs) often present with progressive interstitial lung disease (ILD). The prevalence of ILD varies among patients with RDs, with 11% in RA, 47% in SSc, and 41% in IIMs. Some diagnostic markers, including KL-6, cytokines TNF-α and IL-6, and autoantibodies (anti-CCP), play a crucial role in assessing and predicting the course of pulmonary involvement in RDs...
March 20, 2024: Rheumatology International
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