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https://www.readbyqxmd.com/read/29145680/-a-rare-differential-diagnosis-of-chronic-cough
#1
Michael Dicker, Tino Schneider, Johannes von Kempis, Markus Diethelm
History and admission findings We report on a 62-year-old male patient with dry cough for 3 months, constitutional symptoms and elevated inflammatory markers. Investigations Despite extensive diagnostics no infectious, malignant or rheumatologic disease could be found. Bronchoscopy with bronchoalveolar lavage showed lymphocytosis. 18-FDG-PET/CT demonstrated increased metabolic activity of the aorta and its primary branches. Diagnosis, treatment and course We diagnosed large vessel vasculitis consistent to a subtype of giant cell arteritis (GCA) without cranial manifestation...
November 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29145251/renal-osteodystrophy-presenting-as-a-metabolic-superscan-on-f-18-fdg-pet-ct-a-case-report
#2
Ismaheel Lawal, Alfred Ankrah, Kehinde Ololade, Moshe Modiselle, Mike Sathekge
RATIONALE: F-18 Fluoro Deoxyglucose positron emission tomography and computed tomography (F-18 FDG PET/CT) is a useful modality in the evaluation of patients with malignancies. Increased incidence of lympho-proliferative disorders has been reported in individuals with long-standing end-stage renal disorders treated with renal replacement therapy. PATIENT CONCERNS: A 30-year-old male on peritoneal dialysis on account of end-stage renal disease. He had acute rejection of an earlier transplanted renal allograft...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145250/consort-independent-prognostic-value-of-asphericity-of-pretherapeutic-f-18-fdg-uptake-by-primary-tumors-in-patients-with-breast-cancer
#3
Ji-Hoon Jung, Seung Hyun Son, Do-Hoon Kim, Jeeyeon Lee, Shin Young Jeong, Sang-Woo Lee, Ho Yong Park, Jaetae Lee, Byeong-Cheol Ahn
BACKGROUND: The aim of this study was to evaluate the prognostic implication of asphericity (ASP); spatial irregularity; of pretherapeutic F 2-deoxy-2-fluoro-D-glucose (F FDG) tumor uptake in patients with invasive ductal carcinoma (IDC) of the breast. METHODS: One hundred thirty-one female IDC patients (mean age = 48.1 ± 10.4 years), with pathological tumor size greater than 2 cm were retrospectively evaluated using F FDG positron emission tomography/computed tomography (PET/CT)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29142358/transitional-cell-carcinoma-of-urinary-bladder-manifesting-as-extensive-retroperitoneal-and-axillary-lymph-node-metastasis-an-extremely-rare-case-scenario-detected-by-18-f-fluorodeoxyglucose-positron-emission-tomography-scan
#4
Abhishek Purkayastha, Neelam Sharma, Rekha Vashisth, Braj Kishore
Transitional cell carcinoma (TCC) urinary bladder is known to metastasize to regional lymph nodes (LNs), liver, lung, bone, adrenal glands, and intestine. However, an asymptomatic TCC bladder manifesting as metastatic axillary LN mass and extensive retroperitoneal lymphadenopathy is rarely heard of. A 46-year-old male, smoker, presented with 8 cm × 6 cm right axillary swelling of 1-month duration. Aspiration cytology revealed metastatic deposits of poorly differentiated carcinoma favoring TCC. Metastatic evaluation with (18)F-fluorodeoxyglucose positron emission tomography ((18)FDG-PET) scan showed mass lesion urinary bladder, conglomerate right axillary mass and extensive retroperitoneal LNs with significant metabolic activity, biopsy from which revealed deposits of TCC...
October 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29142352/localized-pontine-uptake-in-fluorine-18-fuorodeoxyglucose-positron-emission-tomography-computed-tomography-in-a-case-of-hyponatremia-a-case-report-and-review-of-literature
#5
Thangalakshmi Sivathapandi, Shelley Simon, Indirani Elangovan
A rare acquired demyelinating lesion of the pons central pontine myelinolysis (CPM) typically occurs after rapid correction of hyponatremia. There is disruption of blood-brain barrier due to osmotic stress allowing access for inflammatory mediators in extravascular brain tissue, which most likely attracts glial cells of the brain, attracts macrophages, and activates astrocytes. We present a case of female with a known history of inflammatory bowel disease who presented with altered sensorium and hyponatremia...
October 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29137009/brain-metabolism-in-patients-with-freezing-of-gait-after-hypoxic-ischemic-brain-injury-a-pilot-study
#6
Seo Yeon Yoon, Sang Chul Lee, Na Young Kim, Young-Sil An, Yong Wook Kim
Movement disorders are 1 of the long-term neurological complications that can occur after hypoxic-ischemic brain injury (HIBI). However, freezing of gait (FOG) after HIBI is rare. The aim of this study was to examine the brain metabolism of patients with FOG after HIBI using F-18 fluoro-2-deoxy-D-glucose positron emission tomography (F-18 FDG PET).We consecutively enrolled 11 patients with FOG after HIBI. The patients' overall brain metabolism was measured by F-18 FDG PET, and we compared their regional brain metabolic activity with that from 15 healthy controls using a voxel-by-voxel-based statistical mapping analysis...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29131698/the-anti-inflammatory-and-antioxidant-effects-of-salvia-officinalis-on-lipopolysaccharide-induced-inflammation-in-rats
#7
Umut Kerem Kolac, Mehmet Cengiz Ustuner, Neslihan Tekin, Derya Ustuner, Emine Colak, Emre Entok
Salvia officinalis, which has a high phenolic acid and flavonoid content, is a powerful antioxidant and anti-inflammatory herb. Inflammation plays an important role in the pathophysiology of many diseases and could cause damage by means of oxidative stress. The aim of this study was to investigate the anti-inflammatory and antioxidant activity of S. officinalis formed lipopolysaccharide (LPS)-induced experimental inflammation model. Four- to five-month-old 42 female Wistar albino rats were divided into six groups...
November 13, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29127247/novel-method-to-detect-and-characterize-f-18-fdg-infiltrations-in-pet-injections-a-single-institution-experience
#8
Razi Muzaffar, Sarah A Frye, Anna Mcmunn, Kelley Ryan, Ron Lattanze, Medhat M Osman
Purpose: A novel Quality Assurance/Quality Control (QA/QC) device provides Time Activity Curves (TACs) which can identify and characterize PET/CT radiotracer infiltrations during the uptake phase. The purpose of this study was to compare rates of infiltration detected by the device compared to standard PET image infiltration rates. We also aimed to assess the value of using the device to improve injection results in our center. Methods: 109 subjects were consented to the study. All subjects had passive device sensors applied to their skin near the injection site and mirrored on the contralateral arm during the entire uptake period...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29125331/-18-fdg-pet-ct-is-useful-in-the-follow-up-of-surgically-treated-patients-with-esophageal-adenocarcinoma
#9
Sonia L Betancourt-Cuellar, Diana P Palacio, Carol C Wu, Brett W Carter, Arlene M Correa, Wayne L Hofstetter, Edith M Marom
PURPOSE: The purpose of this study was to evaluate FDG- PET/CT's performance in the follow-up of patients with surgically treated esophageal adenocarcinoma. MATERIAL AND METHODS: The follow-up FDG-PET/CT scans of 162 consecutive patients with surgically treated esophageal adenocarcinoma were retrospectively reviewed. Histopathological and/or imaging examinations confirmed recurrent disease. The accuracy, sensitivity, specificity, and negative and positive predictive values were calculated...
November 10, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29116563/diagnosis-of-extensive-myocardial-infiltration-by-diffuse-large-b-cell-lymphoma-using-18f-fluorodeoxyglucose-positron-emission-tomography-18-fdg-pet
#10
Angela Y Higgins, Emily Pinto Taylor, Lauren A Baldassarre, Edward J Miller, Lynda E Rosenfeld
No abstract text is available yet for this article.
November 7, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29099613/diagnostic-accuracy-of-f-18-fdg-pet-ct-for-detection-of-peritoneal-carcinomatosis-a-systematic-review-and-meta-analysis
#11
Seong-Jang Kim, Sang-Woo Lee
OBJECTIVE: The current review aimed to investigate the performance of the diagnostic accuracy of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) in detecting peritoneal carcinomatosis (PC) through a systematic review and meta-analysis. METHODS: The MEDLINE via PubMed and EMBASE from the earliest available date of indexing through March 31, 2017, were searched for studies evaluating the diagnostic performance of F-18 FDG PET/CT in detecting PC...
November 3, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29097942/the-effect-of-diagnostic-imaging-on-surgical-treatment-planning-in-diseases-of-the-thymus
#12
REVIEW
Aurel Ottlakan, Bernadett Borda, Zita Morvay, Aniko Maraz, Jozsef Furak
Accurate imaging of the thymus is essential in the diagnosis and surgical treatment of both neoplastic and nonneoplastic conditions. Imaging of the thymus is a rather complex task, which affects both initial diagnosis and further surgical treatment planning. Imaging techniques include a wide armamentary of possibilities, from the most frequently used computed tomography (CT) to 18-fluorodeoxyglucose positron emission tomography- (18-FDG-PET-) CT and chemical shift magnetic resonance imaging (CS-MRI). In cases where surgical treatment is involved diagnostic imaging is of pivotal importance, not only in distinguishing benign from malignant disease but also in making a way among subtypes of thymic conditions...
2017: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/29097410/f-18-fdg-pet-ct-in-erdheim-chester-disease-imaging-findings-and-potential-braf-mutation-biomarker
#13
Jason Young, Geoffrey Bates Johnson, Robert Charles Murphy, Ronald S Go, Stephen M Broski
This study's purpose was to evaluate F-18 fluorodeoxyglucose positron emission tomography - computed tomography (FDG PET-CT) in the diagnosis, management and treatment of Erdheim-Chester disease (ECD). Methods: Our institutional database (2007-2017) was retrospectively reviewed for patients with pathologically-proven ECD. A chart review recorded demographics, clinical information and five categories of clinical impact. Two radiologists in consensus interpreted the images. Imaging findings were correlated with clinical data...
November 2, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29096619/incorporating-18-fdg-pet-defined-pelvic-active-bone-marrow-in-the-automatic-treatment-planning-process-of-anal-cancer-patients-undergoing-chemo-radiation
#14
Pierfrancesco Franco, Christian Fiandra, Francesca Arcadipane, Elisabetta Trino, Francesca Romana Giglioli, Riccardo Ragona, Umberto Ricardi
BACKGROUND: To investigate whether the incorporation of (18)FDG-PET into the automatic treatment planning process may be able to decrease the dose to active bone marrow (BM) for locally advanced anal cancer patients undergoing concurrent chemo-radiation (CHT-RT). METHODS: Ten patients with locally advanced anal cancer were selected. Bone marrow within the pelvis was outlined as the whole outer contour of pelvic bones or employing (18)FDG-PET to identify active BM within osseous structures...
November 2, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29095842/asymmetry-of-cerebral-glucose-metabolism-in-very-low-birth-weight-infants-without-structural-abnormalities
#15
Jae Hyun Park, Chun Soo Kim, Kyoung Sook Won, Jungsu S Oh, Jae Seung Kim, Hae Won Kim
METHODS: Thirty-six VLBW infants who underwent F-18 fluorodeoxyglucose (F-18 FDG) brain PET and MRI were prospectively enrolled, while infants with evidence of parenchymal brain injury on MRI were excluded. The regional glucose metabolic ratio and asymmetry index were calculated. The asymmetry index more than 10% (right > left asymmetry) or less than -10% (left > right asymmetry) were defined as abnormal. Regional cerebral glucose metabolism were compared between right and left cerebral hemispheres, and between the following subgroups: multiple gestations, premature rupture of membrane, bronchopulmonary dysplasia, and low-grade intraventricular hemorrhage...
2017: PloS One
https://www.readbyqxmd.com/read/29094295/patient-page-sarcoidosis-imaging
#16
John P Bois, Panithaya Chareonthaitawee
Optimizing our imaging capabilities for patients with cardiac sarcoidosis is critical as it has diagnostic, prognostic, and therapeutic implications. (18)FDG PET/CT has the highest sensitivity for the detection of CS but requires specific dietary preparation that is difficult for patients to follow which may lead to ineffective suppression of physiologic (18)FDG uptake. This may result in inconclusive scan results in up to 30% of patients undergoing (18)FDG PET/CT imaging for CS. Therefore, it is imperative that we relay to our patients the importance of dietary preparation for CS PET imaging and then provide simple, easy to follow instructions for them...
November 1, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29063177/approach-to-richter-transformation-of-chronic-lymphocytic-leukemia-in-the-era-of-novel-therapies
#17
REVIEW
Maliha Khan, Rabbia Siddiqi, Philip A Thompson
Chronic lymphocytic leukemia (CLL) has a highly variable clinical course. About 2-10% of CLL patients develop aggressive histological transformation, most commonly to diffuse large B cell lymphoma (DLBCL), historically called Richter transformation (RT). Clinical features suggestive of RT include elevated LDH and non-specific symptoms such as fever, weight loss, and lymphadenopathy. 18-fluorodeoxyglucose (18-FDG) uptake is increased on PET scan (standardized uptake value max most commonly ≥ 10). PET/CT study can identify optimal site for excisional biopsy, which is the gold standard for RT diagnosis, as well as aid in disease staging and prognostication...
October 23, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/29061522/prognostic-value-of-fluorine-18-fluoro-2-deoxyglucose-positron-emission-computed-tomography-in-patients-with-unexplained-atrioventricular-block
#18
Tamiruddin A Danwade, Soumen Devidutta, Abhijeet B Shelke, Daljeet Kaur Saggu, Sachin D Yalagudri, Chennapragada Sridevi, Nallamala Krishna Reddy, Calambur Narasimhan
BACKGROUND: The cause of atrioventricular conduction block (AVB) remains unexplained in a significant number of patients. Granulomatous myocarditis (GM) is an uncommon but important cause of AVB. Fluorine-18 fluoro-2-deoxyglucose positron emission computed tomography (18-FDG PET) scan has emerged as a sensitive tool for diagnosing GM. OBJECTIVES: The objective of this study was to evaluate the prognostic value of 18-FDG PET scan in patients with unexplained AVB...
October 20, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29055628/visceral-adiposity-in-psoriasis-is-associated-with-vascular-inflammation-by-18-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-beyond-cardiometabolic-disease-risk-factors-in-an-observational-cohort-study
#19
Joshua P Rivers, Tiffany M Powell-Wiley, Amit K Dey, Justin A Rodante, Jonathan H Chung, Aditya A Joshi, Balaji Natarajan, Aparna P Sajja, Abhishek Chaturvedi, Anshuma Rana, Charlotte L Harrington, Heather L Teague, Benjamin N Lockshin, Mark A Ahlman, Jianhua Yao, Martin P Playford, Joel M Gelfand, Nehal N Mehta
OBJECTIVES: We sought to examine the relationship between visceral adipose tissue (VAT) and vascular inflammation (VI) by (18)fluorodeoxyglucose ((18)FDG) positron-emission tomography (PET)/computed tomography (CT) in psoriasis (PSO). Furthermore, we evaluated whether treatment of PSO modulated VAT and VI. BACKGROUND: PSO, a chronic inflammatory skin disease, is associated with VI by (18)FDG PET/CT and increased cardiometabolic risk including adipose tissue dysregulation...
October 14, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29047296/in%C3%A2-vivo-13-c-mrs-in-the-mouse-brain-at-14-1-tesla-and-metabolic-flux-quantification-under-infusion-of-1-6-13-c2-glucose
#20
Marta Lai, Bernard Lanz, Carole Poitry-Yamate, Jackeline F Romero, Corina M Berset, Cristina Cudalbu, Rolf Gruetter
In vivo (13)C magnetic resonance spectroscopy (MRS) enables the investigation of cerebral metabolic compartmentation while, e.g. infusing (13)C-labeled glucose. Metabolic flux analysis of (13)C turnover previously yielded quantitative information of glutamate and glutamine metabolism in humans and rats, while the application to in vivo mouse brain remains exceedingly challenging. In the present study, (13)C direct detection at 14.1 T provided highly resolved in vivo spectra of the mouse brain while infusing [1,6-(13)C2]glucose for up to 5 h...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
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