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https://www.readbyqxmd.com/read/28938677/comparison-of-18-fdg-pet-pet-ct-and-bone-scintigraphy-for-detecting-bone-metastases-in-patients-with-nasopharyngeal-cancer-a-meta-analysis
#1
Chuanhui Xu, Ruiming Zhang, Huanlei Zhang, Zhenyan Zhang
OBJECTIVE: We performed a meta-analysis to compare the diagnostic efficacy of (18)FDG PET/PET-CT and bone scintigraphy (BS) for diagnosing bone metastatic cancers in nasopharyngeal cancer patients. RESULTS: 6 studies (1238 patients) fulfilled the inclusion criteria. The pooled sensitivities for (18)FDG PET/PET-CT and BS were 0.81 (95% confidence interval [CI] = 0.70 to 0.98) and 0.39 (95% CI = 0.26 to 0.54), specificities were 0.99 (95% CI = 0.98 to 0.99) and 0...
August 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28927125/benign-metastasizing-leiomyoma-and-18-fdg-pet-ct-a-case-report-and-literature-review
#2
Yusuke Sawai, Toshiki Shimizu, Yuta Yamanaka, Maiko Niki, Shosaku Nomura
Pulmonary benign metastasizing leiomyoma (PBML) is a rare disease entity that usually occurs in females of reproductive age with a previous history of uterine myoma. It is typically characterized by multiple pulmonary tumors consisting of benign leiomyoma cells. In the present study, two cases of PBML are discussed. The patient in each case underwent 2-deoxy-2-(fluorine-18)-fluoro-D-glucose positron emission tomography/computed tomography (18-FDG-PET/CT) scans. One patient demonstrated a lack of 18-FDG uptake and a quiescent clinical course...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28913675/diagnostic-utility-of-18-fdg-pet-ct-for-adpkd-cyst-infection
#3
Yoshinosuke Shimamura, Hideki Takizawa
No abstract text is available yet for this article.
September 14, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28905105/diagnostic-and-prognostic-role-of-18-fdg-pet-ct-in-the-management-of-resectable-biliary-tract-cancer
#4
Ka Wing Ma, Tan To Cheung, Wong Hoi She, Kenneth Siu Ho Chok, Albert Chi Yan Chan, Wing Chiu Dai, Wan Hang Chiu, Chung Mau Lo
OBJECTIVES: Role of 18-FDG PET/CT had been well established in other more prevalent malignancies such as colorectal and lung cancer; however, this is not as well defined in cholangiocarcinoma. Literature focusing on the prognostic values of preoperative PET/CT for resectable cholangiocarcinoma is scarce. METHOD: This is a retrospective cohort of 66 consecutive patients who had received curative resection for cholangiocarcinoma from 2010 to 2015. All patients had preoperative 18-FDG PET/CT performed...
September 13, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28887581/multiple-skeletal-muscle-metastases-revealing-a-cardiac-intimal-sarcoma
#5
Amandine Crombé, Pierre-François Lintingre, François Le Loarer, Denis Lachatre, Benjamin Dallaudière
We report the case of a 59-year-old female with progressive bilateral painful swelling of the thighs. MRI revealed multiple intramuscular necrotic masses with similar morphologic patterns. Whole-body CT and 18-FDG PET-CT scans demonstrated additional hypermetabolic muscular masses and a lobulated lesion within the left atrial cavity. As biopsy of a muscular mass was compatible with a poorly differentiated sarcoma with MDM2 oncogene amplification, two diagnoses were discussed: a dedifferentiated liposarcoma with muscle and heart metastases or a primary cardiac sarcoma, mainly a cardiac intimal sarcoma, with muscular metastases, which was finally confirmed by array-comparative genomic hybridization (aCGH) in a sarcoma reference center...
September 8, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28881674/prognostic-significance-of-pd-l1-expression-and-18-f-fdg-pet-ct-in-surgical-pulmonary-squamous-cell-carcinoma
#6
Minghui Zhang, Dalong Wang, Qi Sun, Haihong Pu, Yan Wang, Shu Zhao, Yan Wang, Qiangyuan Zhang
Programmed cell death-ligand 1 (PD-L1) expression is commonly observed in non-small cell lung cancer (NSCLC). The prognostic value of PD-L1 expression and the maximum standardized uptake value (SUVmax) on 18F-Fluorodeoxyglucose positron emission tomography ((18)FDG-PET) in surgical pulmonary squamous cell carcinoma(SCC)remains unclear. Furthermore, the correlation between the SUVmax and PD-L1 expression has not been assessed. Thus, the purpose of this study was to investigate the correlation between PD-L1 expression and the SUVmax on (18)FDG-PET and to examine the prognostic significance of PD-L1 expression and the SUVmax in surgical pulmonary SCC...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28879643/adenoid-cystic-carcinoma-of-the-oral-cavity-radiology-pathology-correlation
#7
Imran Uraizee, Nicole A Cipriani, Daniel T Ginat
Adenoid cystic carcinoma in the oral cavity is an uncommon salivary gland malignancy that has a propensity for perineural spread. A high-grade variant is evidenced by an abundance of pleomorphic cells, loss of the classic biphasic epithelial-myoepithelial growth pattern, and comedonecrosis, as well as elevated Ki-67. CT and MRI can both be useful for demonstrating the extent of invasion in oral cavity-associated adenoid cystic carcinoma, which can attain the inferior alveolar nerve for perineural spread by direct invasion through the mandible...
September 6, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28878853/bilateral-renal-metastasis-of-h%C3%A3-rthle-cell-thyroid-cancer-with-discordant-uptake-between-i-131-sodium-iodide-and-f-18-fdg
#8
Apichaya Claimon, Minseok Suh, Gi Jeong Cheon, Dong Soo Lee, E Edmund Kim, June-Key Chung
Renal metastasis of thyroid cancer is extremely rare. We report the case of a 62-year-old woman with Hürthle cell thyroid cancer (HCTC) with lungs, bones, and bilateral kidneys metastases. The renal metastatic lesions were clearly demonstrated by (131)I whole body scan (WBS) with SPECT/CT. However, they exhibited false-negative results in (18)F-FDG PET/CT, kidney ultrasonography, and contrast-enhanced CT scan. The findings imply that tumors have low glucose metabolism and are able to accumulate radioiodine, which is not commonly found in the relatively aggressive nature of HCTC...
September 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28878850/difference-in-f-18-fdg-uptake-after-esophagogastroduodenoscopy-and-colonoscopy-in-healthy-sedated-subjects
#9
Jong-Ryool Oh, Ji-Hyoung Seo, Woo-Jin Chang, Seung-Il Bae, In-Wook Song, Jin-Gu Bong, Hye-Yeon Jeong, So-Young Park, Jeongyup Bae, Hyundae Yoon
PURPOSE: We aimed to evaluate the difference in fluorodeoxyglucose (FDG) uptake in sedated healthy subjects after they underwent esophagogastroduodenoscopy (EGD) and colonoscopy procedures. METHODS: The endoscopy group (n = 29) included healthy subjects who underwent screening via F-18 FDG positron emission tomography/computed tomography (PET/CT) after an EGD and/or colonoscopy under sedation on the same day. The control group (n = 35) included healthy subjects who underwent screening via PET/CT only...
September 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28878728/patient-affected-by-beta-propeller-protein-associated-neurodegeneration-a-therapeutic-attempt-with-iron-chelation-therapy
#10
Mattia Fonderico, Michele Laudisi, Nico Golfrè Andreasi, Stefania Bigoni, Costanza Lamperti, Celeste Panteghini, Barbara Garavaglia, Miryam Carecchio, Elia Antonio Emanuele, Gian L Forni, Enrico Granieri
Here, we report the case of a 36-year-old patient with a diagnosis of de novo mutation of the WDR45 gene, responsible for beta-propeller protein-associated neurodegeneration, a phenotypically distinct, X-linked dominant form of Neurodegeneration with Brain Iron Accumulation. The clinical history is characterized by a relatively stable intellectual disability and a hypo-bradykinetic and hypertonic syndrome with juvenile onset. Genetic investigations and T1 and T2-weighted MR images align with what is described in literature...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28852831/uterine-intravascular-lymphoma-as-a-cause-of-fever-of-unknown-origin
#11
Jérôme Hadjadj, Hubert Nielly, Eve Piekarski, Wendy Cuccuini, Bénedicte Deau-Fischer, Muriel Hourseau, Khadija Benali, Claire Fieschi, Marc Aletti, Thomas Papo, Eric Oksenhendler, Lionel Galicier, David Boutboul
Primary intravascular large B cell lymphoma (IVL) remains a diagnostic challenge because of non-specific clinical, laboratory and imaging findings. The aim of the study was to analyse the major characteristics of IVL with uterine involvement. We retrospectively collected features of IVL with uterine involvement that was proven histologically or demonstrated by significant (18)FDG uptake on (18)FDG-PET/CT. Findings were compared to a comprehensive literature review. Five patients were identified. All of them were admitted for fever of unknown origin (FUO), with haemophagocytic lymphohistiocytosis in three cases...
August 29, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/28840066/pituitary-carcinoma-a-case-report-and-discussion-of-potential-value-of-combined-use-of-ga-68-dotatate-and-f-18-fdg-pet-ct-scan-to-better-choose-therapy
#12
Heraldo Mendes Garmes, José Barreto Campello Carvalheira, Fabiano Reis, Luciano de Souza Queiroz, Mateus Dal Fabbro, Vanessa de Fatima Porto Souza, Allan de Oliviera Santos
BACKGROUND: Pituitary carcinoma is extremely rare and carries a very poor prognosis. In most cases, apparently indolent tumors become malignant; however, there are no satisfactory biomarkers for predicting tumor behavior. Thus, scientific advances in the search for new biological markers, diagnostic methods, and therapies are needed to improve the prognosis of these patients. CASE DESCRIPTION: We report the case of a woman with initial diagnosis of nonfunctioning pituitary adenoma which evolved to carcinoma after 4 years...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28828589/diagnostic-and-prognostic-value-of-18f-fdg-pet-ct-in-recurrent-germinal-tumor-carcinoma
#13
Pierpaolo Alongi, Laura Evangelista, Federico Caobelli, Marianna Spallino, Luigi Gianolli, Massimo Midiri, Maria Picchio
AIM: The aim of this bicentric retrospective study was to assess the diagnostic performance, the prognostic value, the incremental prognostic value and the impact on therapeutic management of (18)F-FDG PET/CT in patients with suspected recurrent germinal cell testicular carcinoma (GCT). MATERIALS AND METHODS: From the databases of two centers including 31,500 (18)F-FDG PET/CT oncological studies, 114 patients affected by GCT were evaluated in a retrospective study...
August 22, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28815667/diagnostic-performance-of-unenhanced-computed-tomography-and-18-f-fluorodeoxyglucose-positron-emission-tomography-in-indeterminate-adrenal-tumours
#14
Danae A Delivanis, Irina Bancos, Thomas D Atwell, Grant D Schmit, Patrick W Eiken, Neena Natt, Dana Erickson, Spyridoula Maraka, William F Young, Mark A Nathan
OBJECTIVE: Evidence on the diagnostic performance of adrenal imaging is limited. We aimed to assess the diagnostic performance of unenhanced computed tomography (CT) and (18) F-fluorodeoxyglucose ((18) FDG) positron emission tomography (PET)/CT imaging in a high-risk population for adrenal malignancy using an optimal reference standard. DESIGN: Retrospective cohort study. METHODS: Imaging studies of patients with adrenal nodules who underwent adrenal biopsy and/or adrenalectomy between 1994 and 2014 were reviewed and compared to the reference standard of histology...
August 17, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28812120/risk-adapted-robotic-stereotactic-body-radiation-therapy-for-inoperable-early-stage-non-small-cell-lung-cancer
#15
Susanne Temming, Martin Kocher, Erich Stoelben, Lars Hagmeyer, De-Hua Chang, Konrad Frank, Khosro Hekmat, Juergen Wolf, Wolfgang W Baus, Robert Semrau, Christian Baues, S Marnitz
PURPOSE: To evaluate efficacy and toxicity of stereotactic body radiation therapy (SBRT) with CyberKnife® (Accuray, Sunnyvale, CA, USA) in a selected cohort of primary, medically inoperable early-stage non-small cell lung cancer (NSCLC) patients. METHODS: From 2012 to 2016, 106 patients (median age 74 years, range 50-94 years) with primary NSCLC were treated with SBRT using CyberKnife®. Histologic confirmation was available in 87 patients (82%). For mediastinal staging, 92 patients (87%) underwent (18)F-fluorodeoxyglucose positron-emission tomography (18-FDG-PET) and/or endobronchial ultrasound (EBUS)-guided lymph node biopsy or mediastinoscopy...
August 15, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28809123/-18-fdg-pet-ct-in-routine-surveillance-of-asymptomatic-patients-following-treatment-of-sinonasal-neoplasms
#16
Alan D Workman, Jordan T Glicksman, Arjun K Parasher, Ryan M Carey, Steven G Brooks, David W Kennedy, Seyed A Nabavizadeh, Kim O Learned, James N Palmer, Nithin D Adappa
Objective Sinonasal neoplasms have a high rate of recurrence following treatment, and current guidelines support the use of a variety of surveillance techniques. Recent work demonstrates that performance parameters of surveillance modalities may differ with sinonasal tumors in particular when compared with head and neck tumors overall. This study aims to characterize the value of (18)fluorodeoxyglucose ((18)FDG) positron emission tomography/computed tomography (PET/CT) as a screening tool in asymptomatic patients...
August 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28803235/18f-fdg-uptake-in-well-differentiated-neuroendocrine-tumors-correlates-with-both-ki-67-and-vhl-pathway-inactivation
#17
Margot Bucau, Astrid Laurent-Bellue, Nicolas Poté, Olivia Hentic, Jérôme Cros, Nidaa Mikail, Vinciane Rebours, Philippe Ruszniewski, Rachida Lebtahi, Anne Couvelard
<br>Introduction: 18FDG PET-scanner positivity correlates with poor prognosis in neuroendocrine neoplasms (NEN). Glucose transporter 1 (GLUT1) and carbonic anhydrase 9 (CA9) are markers of agressivity in tumors. Together with pVHL, they are involved in tumor cell metabolism via the hypoxia-inducible factor (HIF) signaling pathway. The aim of this study was to compare, in a series of well-differentiated neuroendocrine tumors (NET), the 18-FDG uptake and expression of proliferation marker Ki-67, GLUT-1, CA9 and pVHL...
August 11, 2017: Neuroendocrinology
https://www.readbyqxmd.com/read/28794827/preoperative-18-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-in-early-stage-breast-cancer-rates-of-distant-metastases
#18
Vincent Vinh-Hung, Hendrik Everaert, Karim Farid, Navid Djassemi, Jacqueline Baudin-Veronique, Stefanos Bougas, Yuriy Michailovich, Clarisse Joachim-Contaret, Elsa Cécilia-Joseph, Claire Verschraegen, Nam P Nguyen
AIM: To investigate rates of distant metastases (DM) detected with [18]fluorodeoxyglucose-positron emission tomography/computed tomography ((18)FDG-PET/CT) in early stage invasive breast cancer. METHODS: We searched the English language literature databases of PubMed, EMBASE, ISI Web of Knowledge, Web of Science and Google Scholar, for publications on DM detected in patients who had (18)FDG-PET/CT scans as part of the staging for early stages of breast cancer (stage I and II), prior to or immediately following surgery...
July 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28793848/-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-may-exclude-malignancy-in-sonographically-suspicious-and-scintigraphically-hypofunctional-thyroid-nodules-and-reduce-unnecessary-thyroid-surgeries
#19
Marcus Ruhlmann, Jürgen Ruhlmann, Rainer Görges, Ken Herrmann, Gerald Antoch, Hans-Wilhelm Keller, Verena Ruhlmann
BACKGROUND: The aim of this study was to evaluate whether (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) is useful in the further characterization of sonographically suspicious and scintigraphically hypofunctional thyroid nodules. METHODS: Sixty-five patients with sonographically suspicious thyroid nodules that were hypofunctional on 99m-Tc-pertechnetate scintigraphy (diameter >1 cm) were retrospectively analyzed. All patients underwent evaluation with FDG-PET/CT...
September 15, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28770289/diagnostic-value-of-contrast-enhanced-ct-combined-with-18-fdg-pet-in-patients-selected-for-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-hipec
#20
Antonio Sommariva, Laura Evangelista, Giovanna Pintacuda, Anna Rita Cervino, Gaetano Ramondo, Carlo Riccardo Rossi
PURPOSE: Aim of the study is to assess the reliability and correlation with surgical peritoneal cancer index (PCI) of combined PET/CT and ceCT scans (PET/ceCT) performed in a session in patients with peritoneal carcinomatosis candidates for cytoreductive surgery (CS) and hyperthermic intraperitoneal chemotherapy (HIPEC). METHODS: We retrospectively analyzed data collected from 27 patients with different types of peritoneal carcinomatosis candidates to CS + HIPEC who underwent FDG PET/ceCT in a single session...
August 2, 2017: Abdominal Radiology
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