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Dermal sinus tract

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https://www.readbyqxmd.com/read/27911245/use-of-magnetic-resonance-imaging-to-detect-occult-spinal-dysraphism-in-infants
#1
Brent R O'Neill, Danielle Gallegos, Alex Herron, Claire Palmer, Nicholas V Stence, Todd C Hankinson, C Corbett Wilkinson, Michael H Handler
OBJECTIVE Cutaneous stigmata or congenital anomalies often prompt screening for occult spinal dysraphism (OSD) in asymptomatic infants. While a number of studies have examined the results of ultrasonography (US) screening, less is known about the findings when MRI is used as the primary imaging modality. The object of this study was to assess the results of MRI screening for OSD in infants. METHODS The authors undertook a retrospective review of all infants who had undergone MRI of the lumbar spine to screen for OSD over a 6-year period (September 2006-September 2012)...
December 2, 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27765739/limited-dorsal-myeloschisis-and-congenital-dermal-sinus-comparison-of-clinical-and-mr-imaging-features
#2
S M Lee, J-E Cheon, Y H Choi, I-O Kim, W S Kim, H-H Cho, J Y Lee, K-C Wang
BACKGROUND AND PURPOSE: While limited dorsal myeloschisis is a distinctive form of spinal dysraphism, it may be confused with congenital dermal sinus. The aim of this study was to describe clinical and MR imaging findings of limited dorsal myeloschisis that can distinguish it from congenital dermal sinus. MATERIALS AND METHODS: We retrospectively reviewed the clinical and MR imaging findings of 12 patients with limited dorsal myeloschisis and 10 patients with congenital dermal sinus...
October 20, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27635168/case-report-pseudotail-with-dermal-sinus-tract-and-tethered-cord
#3
Paul Clark, Laurence Davidson
A pseudotail is a very rare, dermal appendage arising from the lumbosacral region with an association with spinal dysraphism. We report a case of a pseudotail in a healthy newborn female with sonographic imaging of a tethered cord and dermal sinus tract with MRI and surgical correlation.
September 2016: Journal of Ultrasound
https://www.readbyqxmd.com/read/27541864/limited-dorsal-myeloschisis-associated-with-dermoid-elements
#4
Sebastian Eibach, Greg Moes, John Zovickian, Dachling Pang
INTRODUCTION: Limited dorsal myeloschisis (LDM) originates from undisjointed neural and cutaneous ectoderms during primary neurulation. Its hallmark is a fibroneural stalk causing tethering on the dorsal spinal cord rostral to the conus. Its treatment is a relatively straightforward resection of the LDM stalk from the spinal cord. METHODS AND RESULTS: On reviewing our series of 75 cases of LDMs, we found that the majority of LDM stalks have only a glioneuronal core within a fibrous stroma, but a small number have been found to have elements of dermoid cyst or a complete dermal sinus tract either contiguous with the fibroneural stalk or incorporated within its glial matrix, not surprising considering the original continuum of cutaneous and neural ectoderm in LDMs' embryogenesis...
August 19, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27330927/nasal-dermal-sinus-associated-with-a-dumbbell-shaped-dermoid-a-case-report
#5
Takafumi Shimogawa, Takato Morioka, Hisasuke Onozawa, Satoshi O Suzuki, Ryutaro Kira
Nasal dermal sinus is a rare congenital anomaly. We report a case of the dermal sinus associated with a dumbbell-shaped dermoid and demonstrate the detailed anatomy. The patient was a boy aged 1 year and 4 months with a small pit at his nasion from birth and developed swelling of the forehead. The sagittal view of a T2-weighted image demonstrated a dumbbell-shaped, mixed intense dermoid at the foramen cecum. The sinus tract was depicted as a strand of isointensity between the dermoid and the nasion. Serial sagittal views of T1-weighted images revealed the capsule of the dermoid enhanced with contrast medium, and that the subcutaneous abscess was in continuity with the dermoid...
June 2016: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/27257806/fate-mapping-of-trps1-daughter-cells-during-cardiac-development-using-novel-trps1-cre-mice
#6
Ahmed G Nomir, Yuto Takeuchi, Junji Fujikawa, Ashraf A El Sharaby, Satoshi Wakisaka, Makoto Abe
Tricho-rhino-phalangeal syndrome (TRPS) is a rare congenital disorder that is characterized by abnormal hair growth and skeletal deformities. These result in sparse hair, short stature, and early onset of joint problems. Recent reports have shown that a relatively high proportion of patients with TRPS exhibit a broad range of congenital heart defects. To determine the regulation of Trps1 transcription in vivo, we generated novel transgenic mice, which expressed Cre recombinase under the murine Trps1 proximal promoter sequence (Trps1-Cre)...
July 2016: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/27184560/intramedullary-dermoid-cyst-infection-mimicking-holocord-tumor-should-radical-resection-be-mandatory-a-case-report
#7
Burak Karaaslan, Göktuğ Ülkü, Murat Ucar, Tuğba Bedir Demirdağ, Arda İnan, Alp Özgün Börcek
BACKGROUND: Dermoid cysts are benign lesions which contain epidermal and dermal elements. Dermoid cysts usually contain a dermal sinus tract but this is not mandatory. Dermoid cysts can manifest by spinal cord infection without a dermal sinus tract. An infected spinal dermoid cyst associated with a holocord spinal abscess poses diagnostic and surgical challenges. Although radical surgical drainage is considered as the main treatment modality for spinal abscess, less extensive surgery for microbiological sampling and appropriate antibiotic treatment can be another alternative modality...
May 16, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27168946/composite-split-cord-malformation-associated-with-a-dermal-sinus-tract-dermoid-cyst-and-epidural-abscess-a-case-report-and-review-of-literature
#8
Saad Akhtar, Abdul Azeem, Muhammad Shahzad Shamim, Muhammad Zubair Tahir
BACKGROUND: Split cord malformation (SCM) is typically present at a single level but rarely, may be present at multiple levels in the spinal cord and can be associated with a wide array of lesions such as myelomeningoceles, lipomas, teratomas, and dermal sinus tracts (DSTs). CASE DESCRIPTION: We describe a case of a 15-month-old female child who presented with high-grade fever and progressive motor weakness in the lower limbs. Magnetic resonance imaging revealed the presence of SCM along with an epidural abscess, DST, and dermoid cyst...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/26962334/pediatric-encephaloceles-a-series-of-20-cases-over-a-period-of-3-years
#9
Shashank Ravindra Ramdurg, M Sukanya, Jayabrata Maitra
BACKGROUND: Encephalocele is the protrusion of the cranial contents beyond the normal confines of the skull through a defect in the calvarium and is far less common than spinal dysraphism. The exact worldwide frequency is not known. AIMS AND OBJECTIVES: To determine the epidemiological features, patterns of encephalocele, and its postsurgical results. MATERIALS AND METHODS: The study was carried from year July 2012 to June 2015. Patients with encephalocele were evaluated for epidemiological characteristics, clinical features, imaging characteristics, and surgical results...
October 2015: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/26892808/prenatal-diagnosis-of-tethered-spinal-cord-associated-with-sacrococcygeal-teratoma
#10
Tugba Sarac Sivrikoz, Recep Has, Aytul Corbacioglu Esmer, Ibrahim Kalelioglu, Atil Yuksel, Orhun Cig Taskin
Tethered spinal cord is mostly caused by myelomeningocele and lipomyelomeningocele, while dermal sinus tract, diastematomyelia, lipoma, tumor, thickened/tight filum terminale, spinal trauma, and spinal surgery are among the other causes. Prenatal diagnosis of tethered cord has been reported, and it is usually associated with neural tube defects. We present an atypical presentation of a tethered spinal cord, which was associated with a sacrococcygeal teratoma and was diagnosed in the 23rd week of pregnancy by ultrasonography...
October 2016: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/26857308/hereditary-angioedema-type-2-presented-as-an-orbital-complication-of-acute-rhinosinusitis
#11
Battal Tahsin Somuk, Göksel Göktas, Samet Özer, Emrah Sapmaz, Yalcın Bas
Hereditary angioedema is an autosomal dominant and life-threatening disorder characterized by recurrent episodes of non-pitting edema affecting the skin, respiratory system and digestive tracts and caused by a congenital deficiency or function defect of the C1 esterase inhibitor. Preseptal cellulitis is defined as an infection of the tissues of the anterior orbital septum. It is generally caused by complications from an upper respiratory tract infection, dacryocystitis, dermal infection, and, rarely, sinusitis...
March 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/26768880/the-human-tail-a-simple-skin-appendage-or-cutaneous-stigma-of-an-anomaly
#12
Cezmi Cagri Turk, Niyazi Nefi Kara, Ali Bacanli
AIM: The human tail is a term to describe skin-covered protrusions in the lumbosacral and coccygeal region, ascribing to the resemblance to the tails in the animals. The first reports dates back to second half of the 19th century, the etiological bases could not been ascertained yet. They are mainly classified as true or pseudo-tails. MATERIAL AND METHODS: Five cases with human tails were diagnosed and managed in our hospital between 2010 and 2014. Their demographic and lesion characteristics are presented...
2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/26539316/spinal-dorsal-dermal-sinus-tract-an-experience-of-21-cases
#13
Ishwar Singh, Seema Rohilla, Prashant Kumar, Saurabh Sharma
BACKGROUND: Spinal dorsal dermal sinus is a rare entity, which usually comes to clinical attention by cutaneous abnormalities, neurologic deficit, and/or infection. The present study was undertaken to know the clinical profile of these patients, to study associated anomalies and to assess the results of surgical intervention. METHODS: Medical records of 21 patients treated for spinal dorsal dermal sinus from September 2007 to December 2013 were reviewed. RESULTS: We had 21 patients with male: female ratio of 13:8...
2015: Surgical Neurology International
https://www.readbyqxmd.com/read/26470622/laser-and-light-based-treatment-options-for-hidradenitis-suppurativa
#14
REVIEW
Iltefat H Hamzavi, James L Griffith, Farhaad Riyaz, Schapoor Hessam, Falk G Bechara
Hidradenitis suppurativa (HS) is a chronic inflammatory disease that commonly develops painful, deep dermal abscesses and chronic, draining sinus tracts. Classically, pharmacologic and surgical therapies have been effective for reducing lesion activity and inflammation, but provide only modest success in the prevention of future recurrences and disease progression. Adjunctive therapies, such as laser and light-based therapies, have become more commonly used in the management of HS. These therapies work to reduce the occurrence of painful HS flare-ups by decreasing the number of hair follicles, sebaceous glands, and bacteria in affected areas, and by ablatively debulking chronic lesions...
November 2015: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/26470613/hidradenitis-suppurativa-in-the-pediatric-population
#15
REVIEW
Carmen Liy-Wong, Elena Pope, Irene Lara-Corrales
Hidradenitis suppurativa (HS) generally appears after puberty, is infrequently seen in younger children, and early onset, which is associated with more widespread disease, is more common in children with a positive family history of HS. When compared with adults with HS, children with HS are more likely to have hormonal imbalances, making hormonal investigations integral to disease management in pediatric patients. HS affects intertriginous areas, presenting with double-ended comedones, tender subcutaneous nodules, purulent discharge, and the formation of sinus tracts, hypertrophic fibrotic scars, and dermal contractures...
November 2015: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/26458220/dermal-sinus-tract-of-the-thoracic-spine-presenting-with-intramedullary-abscess-and-cranial-nerve-deficits
#16
Georgios Papaevangelou, Parmenion P Tsitsopoulos, Nikolaos Flaris, Charalampos Iliadis, Christos Tsonidis
Congenital dermal sinus tract of the spine is an unusual developmental defect which represents a failure of the surface ectoderm and dermal elements to separate from the neuroectoderm. A 15-month-old female presented with high fever, severe right hemiparesis, difficulty breathing and cranial nerve deficits. Magnetic resonance imaging (MRI) of the spine revealed a congenital dermal sinus tract at the Th6 level, an intramedullary collection extending up to the brainstem and a probable intramedullary cystic lesion...
2015: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/26199797/prenatal-diagnosis-of-congenital-dermal-sinus
#17
Sharif Sakr, Yedathore Mohan, Asif Malik, Ghaus Malik, Bernard Gonik
Background Congenital dermal sinus (CDS) is an uncommon form of spinal dysraphism. Although postdelivery identification in the neonate is aided by several associated physical examination findings, establishing this diagnosis prenatally has proven to be elusive. Case Report We present a case of CDS where the prenatal findings at 20 weeks gestation led to the diagnosis, which was confirmed postnatally. The associated protrusion of fibrotic membranes through the sinus tract helped in the identification of this lesion prenatally, but created confusion with a more common type of lesion, an open neural tube defect...
April 2015: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/26097578/bronchogenic-cyst-of-the-conus-medullaris-with-spinal-cord-tethering-a-case-report-and-review-of-the-literature
#18
Ming-Xiang Zou, Jia-Rui Hu, Yi-Jun Kang, Jing Li, Guo-Hua Lv, Xiao-Ling She
Bronchogenic cysts (BCs) are congenital malformations that originate from remnants of the primitive foregut. Intraspinal BCs, especially those of the conus medullaris are rare with only one case reported until now. To date, a bronchogenic cyst with spinal cord tethering has not been previously reported. We reviewed the clinical course of a 44-year-old woman, who presented with low back pain and leg weakness as well as sphincter disturbance. Magnetic resonance imaging showed an intradural oval mass located at the conus medullaris...
2015: International Journal of Clinical and Experimental Pathology
https://www.readbyqxmd.com/read/26030333/congenital-spinal-dermal-tract-how-accurate-is-clinical-and-radiological-evaluation
#19
Martin M Tisdall, Richard D Hayward, Dominic N P Thompson
OBJECT A dermal sinus tract is a common form of occult spinal dysraphism. The presumed etiology relates to a focal failure of disjunction resulting in a persistent adhesion between the neural and cutaneous ectoderm. Clinical and radiological features can appear innocuous, leading to delayed diagnosis and failure to appreciate the implications or extent of the abnormality. If it is left untreated, complications can include meningitis, spinal abscess, and inclusion cyst formation. The authors present their experience in 74 pediatric cases of spinal dermal tract in an attempt to identify which clinical and radiological factors are associated with an infective presentation and to assess the reliability of MRI in evaluating this entity...
June 2015: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/25997405/tethered-cord-syndrome-in-children-a-single-center-experience-with-162-patients
#20
Murat Geyik, Mehmet Alptekin, Ibrahim Erkutlu, Sırma Geyik, Cem Erbas, Serhat Pusat, Cahit Kural
PURPOSE: Tethered cord syndrome (TCS) is not an uncommon clinical problem in children. The aim of this retrospective study is to document our experience on the surgical treatment of TCS in childhood. METHODS: The data of 162 children who underwent surgical treatment for TCS in a 15-year period were reviewed retrospectively. Their demographic, clinical, radiological, and surgical features were documented. They were divided into two groups as primary and secondary TCS, and the surgical technique for each group was demonstrated...
September 2015: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
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