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Dermal sinus tract

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https://www.readbyqxmd.com/read/29618070/congenital-dermal-sinus-and-limited-dorsal-myeloschisis-spectrum-disorders-of-incomplete-dysjuction-between-cutaneous-and-neural-ectoderms
#1
Ji Yeoun Lee, Sung-Hye Park, Sangjoon Chong, Ji Hoon Phi, Seung-Ki Kim, Byung-Kyu Cho, Kyu-Chang Wang
BACKGROUND: The existence of tethering tracts in spinal dysraphism, other than congenital dermal sinus (CDS), has been recognized and has been summated into an integrated concept of limited dorsal myeloschisis (LDM). OBJECTIVE: To elucidate the underlying embryology of LDM in relation to CDS by focusing on the pathological features of special cases of tethering tracts. METHODS: Out of 389 spinal dysraphism patients who were operated on from 2010 to 2016, 5 patients who had tethering tracts composed of both CDS and LDM (or "probable LDM" if only fibrous tissue was found) were identified...
March 29, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29617906/congenital-dermal-sinus-and-limited-dorsal-myeloschisis-spectrum-disorders-of-incomplete-dysjuction-between-cutaneous-and-neural-ectoderms
#2
Ji Yeoun Lee, Sung-Hye Park, Sangjoon Chong, Ji Hoon Phi, Seung-Ki Kim, Byung-Kyu Cho, Kyu-Chang Wang
BACKGROUND: The existence of tethering tracts in spinal dysraphism, other than congenital dermal sinus (CDS), has been recognized and has been summated into an integrated concept of limited dorsal myeloschisis (LDM). OBJECTIVE: To elucidate the underlying embryology of LDM in relation to CDS by focusing on the pathological features of special cases of tethering tracts. METHODS: Out of 389 spinal dysraphism patients who were operated on from 2010 to 2016, 5 patients who had tethering tracts composed of both CDS and LDM (or "probable LDM" if only fibrous tissue was found) were identified...
March 29, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29483975/intralesional-diode-laser-1064-nm-for-the-treatment-of-hidradenitis-suppurativa-a-report-of-twenty-patients
#3
Gabriella Fabbrocini, Katlein França, Torello Lotti, Claudio Marasca, Maria Carmela Annunziata, Sara Cacciapuoti, Anna Masarà, Marco Romanelli, Jacopo Lotti, Uwe Wollina, Georgi Tchernev, Nicola Zerbinati
AIM: Hidradenitis suppurativa (HS) is a chronic inflammatory disease, commonly characterized by painful, deep dermal abscesses and chronic draining sinus tracts. Recently, laser and light-based therapies have become more commonly used in the management of HS. MATERIAL AND METHODS: We report 20 HS patients treated with a 1064 nm wavelength, emitted from a diode laser, launched in an optical fibre through intracavitary modalities. RESULTS: Each patient underwent four laser sessions, one every two weeks...
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29279962/double-dermal-sinus-tracts-of-the-cervical-and-thoracic-regions-a-case-in-a-3-year-old-child-and-review-of-the-literature
#4
Oliver D Mrowczynski, Jessica R Lane, Mohammadali M Shoja, Charles S Specht, Sara T Langan, Elias B Rizk
INTRODUCTION: Dermal sinus tracts are rare congenital abnormalities characterized by an epithelium-lined tract that extends from the subcutaneous tissue to the underlying thecal sac or neural tube. These developmental anomalies can present asymptomatically with a cutaneous dimple or with devastating complications including recurrent episodes of meningitis, or neurological complications including paralysis. Dermal sinus tracts generally occur as single lesions, and the presentation of midline double dermal sinus tracts of the cervical and thoracic regions has not been previously described...
December 26, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29174077/occipital-dermal-sinus-tract
#5
Laura M Prolo, Gerald A Grant
No abstract text is available yet for this article.
February 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29150882/plantar-eumycetoma-by-madurella-mycetomatis-in-a-heart-transplanted-patient-living-in-portugal
#6
LETTER
N Cunha, M L Martins, N Fradinho, P Martins, J Cabete
No abstract text is available yet for this article.
November 17, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29075839/occult-spinal-dysraphisms-in-newborns-with-skin-markers-role-of-ultrasonography-and-magnetic-resonance-imaging
#7
E Ausili, G Maresca, L Massimi, L Morgante, C Romagnoli, C Rendeli
PURPOSE: The purpose of this paper is to investigate occult spinal dysraphisms (OSD) using lumbar ultrasonography (LUS) in newborns presenting with specific skin markers or sacrococcygeal dimple. METHOD: From 2012 to 2015, we performed LUS in newborns with cutaneous stigmata and/or sacroccygeal dimple. Magnetic resonance imaging (MRI) was performed in all patients with abnormal ultrasound or features of neurological involvement in order to detect spinal lesions...
February 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28937919/neurosurgical-management-of-a-rare-congenital-supratentorial-neurenteric-cyst-with-associated-nasal-dermal-sinus-case-report
#8
REVIEW
Paul MacMahon, Stanca Iacob, Sarah E Bach, Eric T Elwood, Julian J Lin, Anthony M Avellino
The authors describe the case of a patient with the classic clinical presentation and radiographic features of a nasal dermal sinus with an associated intracranial cyst; however, histopathology revealed that the intracranial cyst was neurenteric instead of the typical epidermoid or dermoid cyst. Preoperative assessment included CT and MRI, which revealed a direct communication between the patient's nasal polypoid lesion and the anterior skull base via the foramen cecum. At the hands of a multidisciplinary plastic surgery and neurosurgery team, the patient underwent concurrent gross-total resection of the nasal polypoid lesion, the intracranial intradural cystic lesion, and their interconnecting tract...
December 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28538742/epidemiologic-and-clinical-features-of-hidradenitis-suppurativa
#9
Isha Parulkar, Heba Haleem, So Yeon Paek
Hidradenitis suppurativa (HS) is an inflammatory condition characterized by recurrent abscesses which may result in sinus tracts and dermal scarring. This article reviews current epidemiologic data on HS in diverse populations, including prevalence based on geography, age, gender, ethnicity, and details the spectrum of clinical features of hidradenitis suppurativa with discussion of disease severity and risk factors. Recently proposed HS diagnostic criteria are also presented.
June 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28448267/endogenous-thymosin-%C3%AE-4-expression-in-sacrococcygeal-pilonidal-sinus-disease-a-retrospective-immunohistochemical-analysis-of-excisional-skin-biopsy-samples
#10
Sevinc Sahin
Thymosin beta 4 (Tβ4) is a peptide that has been shown in dermal, corneal, and cardiac preclinical injury models to potentially affect tissue protection, regeneration, and repair. Sacrococcygeal pilonidal sinus disease (SPSD) is a chronic inflammatory disorder associated with a high incidence of recurrence, chronic fistulation, and a challenging postoperative surgical wound healing process. Retrospectively, an immunohistochemical analysis was conducted to evaluate endogenous Tβ4 expression in excisional skin biopsies from patients with SPSD...
April 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/28381141/rare-inverted-verrucous-carcinoma-carcinoma-cuniculatum-of-the-sacrogluteal-region
#11
David John Tobias McArdle, John Patrick McArdle, Frances Lee, Emilio Dino Mignanelli
A 49-year-old woman with a past history of several infundibular cysts in the head and neck region presented with a 6-month history of a nonhealing perianal abscess on a background of 13 years of chronic sacral-buttock abscesses and discharging sinuses as part of hidradenitis suppurativa. After 2 surgical procedures and inadequate healing, a wide local excision was performed. The surgical specimen revealed an extensive, infiltrating, cystic and deeply penetrating, dermal and subcutaneous neoplasm with multiple fistulous tracts extending to the skin surface...
February 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28362184/surveillance-survey-of-family-history-in-children-with-neural-tube-defects
#12
Esther B Dupépé, Daxa M Patel, Brandon G Rocque, Betsy Hopson, Anastasia A Arynchyna, E Ralee' Bishop, Jeffrey P Blount
OBJECTIVE Although there are known risk factors for the development of neural tube defects (NTDs), little is known regarding the role of family history. The authors' goal in this study is to describe the family history in their population of patients with NTDs. METHODS Surveys were completed for 254 patients who were accompanied by their biological mother during their annual visit to the multidisciplinary Spina Bifida Clinic at Children's of Alabama. An NTD has been diagnosed in all patients who are seen in this clinic (myelomeningocele, lipomeningocele, split cord malformation, and congenital dermal sinus tract)...
June 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27911245/use-of-magnetic-resonance-imaging-to-detect-occult-spinal-dysraphism-in-infants
#13
Brent R O'Neill, Danielle Gallegos, Alex Herron, Claire Palmer, Nicholas V Stence, Todd C Hankinson, C Corbett Wilkinson, Michael H Handler
OBJECTIVE Cutaneous stigmata or congenital anomalies often prompt screening for occult spinal dysraphism (OSD) in asymptomatic infants. While a number of studies have examined the results of ultrasonography (US) screening, less is known about the findings when MRI is used as the primary imaging modality. The object of this study was to assess the results of MRI screening for OSD in infants. METHODS The authors undertook a retrospective review of all infants who had undergone MRI of the lumbar spine to screen for OSD over a 6-year period (September 2006-September 2012)...
February 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27765739/limited-dorsal-myeloschisis-and-congenital-dermal-sinus-comparison-of-clinical-and-mr-imaging-features
#14
COMPARATIVE STUDY
S M Lee, J-E Cheon, Y H Choi, I-O Kim, W S Kim, H-H Cho, J Y Lee, K-C Wang
BACKGROUND AND PURPOSE: While limited dorsal myeloschisis is a distinctive form of spinal dysraphism, it may be confused with congenital dermal sinus. The aim of this study was to describe clinical and MR imaging findings of limited dorsal myeloschisis that can distinguish it from congenital dermal sinus. MATERIALS AND METHODS: We retrospectively reviewed the clinical and MR imaging findings of 12 patients with limited dorsal myeloschisis and 10 patients with congenital dermal sinus...
January 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27635168/case-report-pseudotail-with-dermal-sinus-tract-and-tethered-cord
#15
Paul Clark, Laurence Davidson
A pseudotail is a very rare, dermal appendage arising from the lumbosacral region with an association with spinal dysraphism. We report a case of a pseudotail in a healthy newborn female with sonographic imaging of a tethered cord and dermal sinus tract with MRI and surgical correlation.
September 2016: Journal of Ultrasound
https://www.readbyqxmd.com/read/27541864/limited-dorsal-myeloschisis-associated-with-dermoid-elements
#16
Sebastian Eibach, Greg Moes, John Zovickian, Dachling Pang
INTRODUCTION: Limited dorsal myeloschisis (LDM) originates from undisjointed neural and cutaneous ectoderms during primary neurulation. Its hallmark is a fibroneural stalk causing tethering on the dorsal spinal cord rostral to the conus. Its treatment is a relatively straightforward resection of the LDM stalk from the spinal cord. METHODS AND RESULTS: On reviewing our series of 75 cases of LDMs, we found that the majority of LDM stalks have only a glioneuronal core within a fibrous stroma, but a small number have been found to have elements of dermoid cyst or a complete dermal sinus tract either contiguous with the fibroneural stalk or incorporated within its glial matrix, not surprising considering the original continuum of cutaneous and neural ectoderm in LDMs' embryogenesis...
January 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27330927/nasal-dermal-sinus-associated-with-a-dumbbell-shaped-dermoid-a-case-report
#17
Takafumi Shimogawa, Takato Morioka, Hisasuke Onozawa, Satoshi O Suzuki, Ryutaro Kira
Nasal dermal sinus is a rare congenital anomaly. We report a case of the dermal sinus associated with a dumbbell-shaped dermoid and demonstrate the detailed anatomy. The patient was a boy aged 1 year and 4 months with a small pit at his nasion from birth and developed swelling of the forehead. The sagittal view of a T2-weighted image demonstrated a dumbbell-shaped, mixed intense dermoid at the foramen cecum. The sinus tract was depicted as a strand of isointensity between the dermoid and the nasion. Serial sagittal views of T1-weighted images revealed the capsule of the dermoid enhanced with contrast medium, and that the subcutaneous abscess was in continuity with the dermoid...
June 2016: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/27257806/fate-mapping-of-trps1-daughter-cells-during-cardiac-development-using-novel-trps1-cre-mice
#18
Ahmed G Nomir, Yuto Takeuchi, Junji Fujikawa, Ashraf A El Sharaby, Satoshi Wakisaka, Makoto Abe
Tricho-rhino-phalangeal syndrome (TRPS) is a rare congenital disorder that is characterized by abnormal hair growth and skeletal deformities. These result in sparse hair, short stature, and early onset of joint problems. Recent reports have shown that a relatively high proportion of patients with TRPS exhibit a broad range of congenital heart defects. To determine the regulation of Trps1 transcription in vivo, we generated novel transgenic mice, which expressed Cre recombinase under the murine Trps1 proximal promoter sequence (Trps1-Cre)...
2016: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/27184560/intramedullary-dermoid-cyst-infection-mimicking-holocord-tumor-should-radical-resection-be-mandatory-a-case-report
#19
Burak Karaaslan, Göktuğ Ülkü, Murat Ucar, Tuğba Bedir Demirdağ, Arda İnan, Alp Özgün Börcek
BACKGROUND: Dermoid cysts are benign lesions which contain epidermal and dermal elements. Dermoid cysts usually contain a dermal sinus tract but this is not mandatory. Dermoid cysts can manifest by spinal cord infection without a dermal sinus tract. An infected spinal dermoid cyst associated with a holocord spinal abscess poses diagnostic and surgical challenges. Although radical surgical drainage is considered as the main treatment modality for spinal abscess, less extensive surgery for microbiological sampling and appropriate antibiotic treatment can be another alternative modality...
November 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27168946/composite-split-cord-malformation-associated-with-a-dermal-sinus-tract-dermoid-cyst-and-epidural-abscess-a-case-report-and-review-of-literature
#20
Saad Akhtar, Abdul Azeem, Muhammad Shahzad Shamim, Muhammad Zubair Tahir
BACKGROUND: Split cord malformation (SCM) is typically present at a single level but rarely, may be present at multiple levels in the spinal cord and can be associated with a wide array of lesions such as myelomeningoceles, lipomas, teratomas, and dermal sinus tracts (DSTs). CASE DESCRIPTION: We describe a case of a 15-month-old female child who presented with high-grade fever and progressive motor weakness in the lower limbs. Magnetic resonance imaging revealed the presence of SCM along with an epidural abscess, DST, and dermoid cyst...
2016: Surgical Neurology International
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