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Dermal sinus

S M Lee, J-E Cheon, Y H Choi, I-O Kim, W S Kim, H-H Cho, J Y Lee, K-C Wang
BACKGROUND AND PURPOSE: While limited dorsal myeloschisis is a distinctive form of spinal dysraphism, it may be confused with congenital dermal sinus. The aim of this study was to describe clinical and MR imaging findings of limited dorsal myeloschisis that can distinguish it from congenital dermal sinus. MATERIALS AND METHODS: We retrospectively reviewed the clinical and MR imaging findings of 12 patients with limited dorsal myeloschisis and 10 patients with congenital dermal sinus...
October 20, 2016: AJNR. American Journal of Neuroradiology
Paul Clark, Laurence Davidson
A pseudotail is a very rare, dermal appendage arising from the lumbosacral region with an association with spinal dysraphism. We report a case of a pseudotail in a healthy newborn female with sonographic imaging of a tethered cord and dermal sinus tract with MRI and surgical correlation.
September 2016: Journal of Ultrasound
Guru Dutta Satyarthee, Nitin Verma, A K Mahapatra
Twin nasal dermal sinus with associated intracranial dermoid located in interfalcial region is a very rare occurrence and is reported only in the occipital and temporal regions. However, multiple sinuses located in the canthus and dorsum of nose are not reported till date. Authors report an interesting first case of interfalcial dermoid cyst associated with twin discharging dermal sinuses, who underwent successful surgical repair in the world literature. The authors report the management of an unusual case and the review has been discussed briefly...
April 2016: Journal of Pediatric Neurosciences
Erin E Mattson, Christopher D Marshall
Histological data from terrestrial, semiaquatic, and fully aquatic mammal vibrissa (whisker) studies indicate that follicle microstructure and innervation vary across the mystacial vibrissal array (i.e. medial microvibrissae to lateral macrovibrissae). However, comparative data are lacking, and current histological studies on pinniped vibrissae only focus on the largest ventrolateral vibrissae. Consequently, we investigated the microstructure, medial-to-lateral innervation, and morphometric trends in harp seal (Pagophilus groenlandicus) vibrissal follicle-sinus complexes (F-SCs)...
2016: Brain, Behavior and Evolution
Sebastian Eibach, Greg Moes, John Zovickian, Dachling Pang
INTRODUCTION: Limited dorsal myeloschisis (LDM) originates from undisjointed neural and cutaneous ectoderms during primary neurulation. Its hallmark is a fibroneural stalk causing tethering on the dorsal spinal cord rostral to the conus. Its treatment is a relatively straightforward resection of the LDM stalk from the spinal cord. METHODS AND RESULTS: On reviewing our series of 75 cases of LDMs, we found that the majority of LDM stalks have only a glioneuronal core within a fibrous stroma, but a small number have been found to have elements of dermoid cyst or a complete dermal sinus tract either contiguous with the fibroneural stalk or incorporated within its glial matrix, not surprising considering the original continuum of cutaneous and neural ectoderm in LDMs' embryogenesis...
August 19, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Anna Kurayev, Huda Ashkar, Ami Saraiya, Alice B Gottlieb
Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by significant morbidity. The clinical course of HS ranges from relatively mild cases characterized by recurrent tender, subcutaneous, inflammatory nodules to severe cases demonstrating painful, deep dermal abscesses, fibrosis, draining sinuses, and hypertrophic scars. Conventional treatment options for management of HS include topical and systemic antibiotics, antiandrogens, fumarates, biguanides, retinoids, immunosuppressive drugs, laser and phototherapy, and surgical excision...
August 1, 2016: Journal of Drugs in Dermatology: JDD
Hideyuki Okui, Chie Fukasawa, Shoko Tokutake, Haruka Takei, Junichi Sato, Tadashi Hoshino
We report the case of a pediatric patient in whom a spinal congenital dermal sinus was detected after the onset of anaerobic bacterial meningitis. The patient was a 4-month-old boy. He had a recurrent fever for 2 weeks before admission. On admission, he presented with a convulsive status and a bulging anterior fontanel. The previously consulted physician had made a diagnosis of bacterial meningitis. Spinal fluid cultures tested positive for Peptoniphilus asaccharolyticus. Magnetic resonance imaging (MRI) showed a spinal subdural abscess and cranial subdural hydrops; therefore, the patient was transported to our hospital for surgical treatment...
May 2016: Kansenshōgaku Zasshi. the Journal of the Japanese Association for Infectious Diseases
Andrew J Clark, Callie H Crawford, Brooke D King, Andrew M Demas, Theodore A Uyeno
Hagfishes (Myxinidae) often integrate whole-body knotting movements with jawless biting motions when reducing large marine carcasses to ingestible items. Adaptations for these behaviors include complex arrangements of axial muscles and flexible, elongate bodies without vertebrae. Between the axial muscles and the hagfish skin is a large, blood-filled subcutaneous sinus devoid of the intricate, myoseptal tendon networks characteristic of the taut skins of other fishes. We propose that the loose-fitting skin of the hagfish facilitates the formation and manipulation of body knots, even if it is of little functional significance to steady swimming...
June 2016: Biological Bulletin
Takafumi Shimogawa, Takato Morioka, Hisasuke Onozawa, Satoshi O Suzuki, Ryutaro Kira
Nasal dermal sinus is a rare congenital anomaly. We report a case of the dermal sinus associated with a dumbbell-shaped dermoid and demonstrate the detailed anatomy. The patient was a boy aged 1 year and 4 months with a small pit at his nasion from birth and developed swelling of the forehead. The sagittal view of a T2-weighted image demonstrated a dumbbell-shaped, mixed intense dermoid at the foramen cecum. The sinus tract was depicted as a strand of isointensity between the dermoid and the nasion. Serial sagittal views of T1-weighted images revealed the capsule of the dermoid enhanced with contrast medium, and that the subcutaneous abscess was in continuity with the dermoid...
June 2016: Journal of Neurological Surgery Reports
Khansa Abderrahmen, Jallel Kallel, Hafedh Jemel
No abstract text is available yet for this article.
May 13, 2016: Pediatrics and Neonatology
Ahmed G Nomir, Yuto Takeuchi, Junji Fujikawa, Ashraf A El Sharaby, Satoshi Wakisaka, Makoto Abe
Tricho-rhino-phalangeal syndrome (TRPS) is a rare congenital disorder that is characterized by abnormal hair growth and skeletal deformities. These result in sparse hair, short stature, and early onset of joint problems. Recent reports have shown that a relatively high proportion of patients with TRPS exhibit a broad range of congenital heart defects. To determine the regulation of Trps1 transcription in vivo, we generated novel transgenic mice, which expressed Cre recombinase under the murine Trps1 proximal promoter sequence (Trps1-Cre)...
July 2016: Genesis: the Journal of Genetics and Development
Burak Karaaslan, Göktuğ Ülkü, Murat Ucar, Tuğba Bedir Demirdağ, Arda İnan, Alp Özgün Börcek
BACKGROUND: Dermoid cysts are benign lesions which contain epidermal and dermal elements. Dermoid cysts usually contain a dermal sinus tract but this is not mandatory. Dermoid cysts can manifest by spinal cord infection without a dermal sinus tract. An infected spinal dermoid cyst associated with a holocord spinal abscess poses diagnostic and surgical challenges. Although radical surgical drainage is considered as the main treatment modality for spinal abscess, less extensive surgery for microbiological sampling and appropriate antibiotic treatment can be another alternative modality...
May 16, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Saad Akhtar, Abdul Azeem, Muhammad Shahzad Shamim, Muhammad Zubair Tahir
BACKGROUND: Split cord malformation (SCM) is typically present at a single level but rarely, may be present at multiple levels in the spinal cord and can be associated with a wide array of lesions such as myelomeningoceles, lipomas, teratomas, and dermal sinus tracts (DSTs). CASE DESCRIPTION: We describe a case of a 15-month-old female child who presented with high-grade fever and progressive motor weakness in the lower limbs. Magnetic resonance imaging revealed the presence of SCM along with an epidural abscess, DST, and dermoid cyst...
2016: Surgical Neurology International
Ali Cengiz, Özgür Öner, Ali Fuat Tekin, Arzu Cengiz, İsmet Tolu
No abstract text is available yet for this article.
April 13, 2016: Spine Journal: Official Journal of the North American Spine Society
M Eliezer, J Le Moal, J-N Dacher, P-H Vivier
No abstract text is available yet for this article.
May 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Steven A Bryce, Ruairi A M Wilson, Eleanor M Tiplady, Darren L Asquith, Shannon K Bromley, Andrew D Luster, Gerard J Graham, Robert J B Nibbs
Dermal dendritic cells and epidermal Langerhans cells are APCs that migrate from skin to draining lymph nodes (LN) to drive peripheral tolerance and adaptive immunity. Their migration requires the chemokine receptor CCR7, which directs egress from the skin via dermal lymphatic vessels and extravasation into the LN parenchyma from lymph in the subcapsular sinus. CCR7 is activated by two chemokines: CCL19 and CCL21. CCL21 alone is sufficient for the migration of APCs from skin to LN. CCL19 and CCL21 also bind atypical chemokine receptor (ACKR) 4...
April 15, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
Shashank Ravindra Ramdurg, M Sukanya, Jayabrata Maitra
BACKGROUND: Encephalocele is the protrusion of the cranial contents beyond the normal confines of the skull through a defect in the calvarium and is far less common than spinal dysraphism. The exact worldwide frequency is not known. AIMS AND OBJECTIVES: To determine the epidemiological features, patterns of encephalocele, and its postsurgical results. MATERIALS AND METHODS: The study was carried from year July 2012 to June 2015. Patients with encephalocele were evaluated for epidemiological characteristics, clinical features, imaging characteristics, and surgical results...
October 2015: Journal of Pediatric Neurosciences
A S Kamat, N S Thango, M Ben Husein
Intramedullary spinal cord abscesses are rare and potentially devastating lesions usually associated with other infective processes such as bacterial endocarditis, or pulmonary or urogenital infection. We describe a 2-year-old girl who presented with an infected dermal sinus leading to an intraspinal abscess. This abscess eventually spread and involved the entire neural axis leaving her quadriparetic. Drainage of the abscess resulted in recovery and the child regained normal function of her limbs. To our knowledge this is the first documented case of an intramedullary abscess involving the entire neural axis...
August 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Tugba Sarac Sivrikoz, Recep Has, Aytul Corbacioglu Esmer, Ibrahim Kalelioglu, Atil Yuksel, Orhun Cig Taskin
Tethered spinal cord is mostly caused by myelomeningocele and lipomyelomeningocele, while dermal sinus tract, diastematomyelia, lipoma, tumor, thickened/tight filum terminale, spinal trauma, and spinal surgery are among the other causes. Prenatal diagnosis of tethered cord has been reported, and it is usually associated with neural tube defects. We present an atypical presentation of a tethered spinal cord, which was associated with a sacrococcygeal teratoma and was diagnosed in the 23rd week of pregnancy by ultrasonography...
October 2016: Journal of Clinical Ultrasound: JCU
Battal Tahsin Somuk, Göksel Göktas, Samet Özer, Emrah Sapmaz, Yalcın Bas
Hereditary angioedema is an autosomal dominant and life-threatening disorder characterized by recurrent episodes of non-pitting edema affecting the skin, respiratory system and digestive tracts and caused by a congenital deficiency or function defect of the C1 esterase inhibitor. Preseptal cellulitis is defined as an infection of the tissues of the anterior orbital septum. It is generally caused by complications from an upper respiratory tract infection, dacryocystitis, dermal infection, and, rarely, sinusitis...
March 2016: International Journal of Pediatric Otorhinolaryngology
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