Fei Gao, Tingbin Zhang, Xiaoli Liu, Anujit Ghosal, Dan Wang, Wensheng Xie, Yongsan Li, Xing Wang, Lei Tao, Jing Yu, Yen Wei, Haiming Fan, Lingyun Zhao
Magnetic mediated hyperthermia (MMT) is emerging as one of the promising techniques which could synergistically treat cancer along with current treatment techniques such as chemo- and radiotherapy, and trigger on demand release of therapeutic macromolecules. However, the low specific absorption rate (SAR) and potential in vivo toxicity of magnetic nanomaterials as the MMT mediators restrict the new advancements in MMT treatment. Herein, for the first trial, the unique inductive heating property of hypertonic saline (HTS), a clinical applied solution exhibiting several physiological effect under alterative magnetic field (AMF), was systematically investigated...
February 25, 2019: ACS Applied Materials & Interfaces