keyword
https://read.qxmd.com/read/38096874/importance-and-use-of-corneal-biomechanics-and-its-diagnostic-utility
#1
JOURNAL ARTICLE
Arturo Ramirez-Miranda, Simran Mangwani-Mordani, José Y Arteaga-Rivera, Renato Ambrosio, Alejandro Navas, Enrique O Graue-Hernandez, Jorge E Valdez-Garcia
The study of corneal biomechanics has become relevant in recent years due to its possible applications in the diagnosis, management, and treatment of various diseases such as glaucoma, keratorefractive surgery and different corneal diseases. The clinical biomechanical investigation has become of great importance in the setting of refractive surgery to identify patients at higher risk of developing iatrogenic ectasia. This review focuses on two of the technologies available for clinical use, the Ocular Response Analyzer (Reichert Ophthalmic Instruments, Buffalo, NY, USA) and the Corvis ST (Oculus Optikgergäte GmbH, Wetzlar, Germany)...
2023: Cirugia y Cirujanos
https://read.qxmd.com/read/37919821/multimodal-diagnostics-for-keratoconus-and-ectatic-corneal-diseases-a-paradigm-shift
#2
REVIEW
Renato Ambrósio, Marcella Q Salomão, Lorena Barros, João Batista R da Fonseca Filho, Jaime Guedes, Alexandre Neto, Aydano P Machado, Bernardo T Lopes, Nelson Sena, Louise Pellegrino Gomes Esporcatte
Different diagnostic approaches for ectatic corneal diseases (ECD) include screening, diagnosis confirmation, classification of the ECD type, severity staging, prognostic evaluation, and clinical follow-up. The comprehensive assessment must start with a directed clinical history. However, multimodal imaging tools, including Placido-disk topography, Scheimpflug three-dimensional (3D) tomography, corneal biomechanical evaluations, and layered (or segmental) tomography with epithelial thickness by optical coherence tomography (OCT), or digital very high-frequency ultrasound (dVHF-US) serve as fundamental complementary exams for measuring different characteristics of the cornea...
November 3, 2023: Eye and Vision (London, England)
https://read.qxmd.com/read/37795607/iatrogenic-spinal-intradural-hemorrhage-in-a-patient-with-dural-ectasia-in-marfan-syndrome
#3
JOURNAL ARTICLE
Giulio Vara, Gianfranco Vornetti, Luca Spinardi
No abstract text is available yet for this article.
October 5, 2023: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/37348513/iatrogenic-keratectasia-after-refractive-surgery-causes-prophylaxis-therapy
#4
JOURNAL ARTICLE
Felix Mathias Wagner, Walter Sekundo
Iatrogenic keratectasia is induced thinning and protrusion of the cornea after laser refractive surgery. Known risk factors include an excessively thin postoperative residual stromal bed, a thicker flap, or preoperatively undetected evidence of preexisting subclinical keratoconus. The rate of post-refractive ectasia in eyes without identifiable preoperative risk factors is 20 per 100 000 eyes for photorefractive keratectomy, 90 per 100 000 eyes for laser in situ keratomileusis, and 11 per 100 000 eyes for small incision lenticule extraction...
June 2023: Klinische Monatsblätter Für Augenheilkunde
https://read.qxmd.com/read/36690333/therapeutic-non-ectasia-applications-of-cornea-cross-linking
#5
JOURNAL ARTICLE
Haitham Al-Mahrouqi, Isabella Mei Yan Cheung, Lize Angelo, Tzu-Ying Yu, Akilesh Gokul, Mohammed Ziaei
Corneal cross-linking is a photopolymerization technique traditionally used to strengthen corneal tissue. Corneal cross-linking utilizes riboflavin (vitamin B2) as a photosensitizer and ultraviolet-A light (UVA) to create strong covalent bonds within the corneal stroma, increasing tissue stiffness. Multiple studies have demonstrated corneal cross-linking's effectiveness in treating corneal ectasia, a progressive, degenerative, and non-inflammatory thinning disorder, as quantified by key tomographic, refractive, and visual parameters...
January 23, 2023: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://read.qxmd.com/read/36553038/enhanced-diagnostics-for-corneal-ectatic-diseases-the-whats-the-whys-and-the-hows
#6
REVIEW
Louise Pellegrino Gomes Esporcatte, Marcella Q Salomão, Alexandre Batista da Costa Neto, Aydano P Machado, Bernardo T Lopes, Renato Ambrósio
There are different fundamental diagnostic strategies for patients with ectatic corneal diseases (ECDs): screening, confirmation of the diagnosis, classification of the type of ECD, severity staging, prognostic assessment, and clinical follow-up. The conscious application of such strategies enables individualized treatments. The need for improved diagnostics of ECD is related to the advent of therapeutic refractive procedures that are considered prior to keratoplasty. Among such less invasive procedures, we include corneal crosslinking, customized ablations, and intracorneal ring segment implantation...
December 2, 2022: Diagnostics
https://read.qxmd.com/read/36178505/assessment-of-the-corneal-biomechanical-features-of-granular-corneal-dystrophy-type-2-using-dynamic-ultra-high-speed-scheimpflug-imaging
#7
JOURNAL ARTICLE
Akira Tanikawa, Takeshi Soma, Atsuya Miki, Shizuka Koh, Yoshiyuki Kitaguchi, Naoyuki Maeda, Yoshinori Oie, Satoshi Kawasaki, Kohji Nishida
PURPOSE: To evaluate the corneal biomechanical features of eyes with granular corneal dystrophy type 2 (GCD2) by analyzing corneal biomechanical indices obtained using a Corvis ST (CST) dynamic ultra-high-speed Scheimpflug imaging device. METHODS: In this retrospective case-control study, 35 CST parameters were compared in normal eyes (control) and eyes of patients with GCD2 treated at Osaka University Hospital, Osaka, Japan. The parameters included the Corvis Biomechanical Index (CBI), which is important in differentiating eyes with keratoconus from normal eyes...
September 30, 2022: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36138148/two-year-stability-of-posterior-corneal-surface-after-transepithelial-photorefractive-keratectomy-with-a-residual-stromal-thickness-less-than-350-%C3%AE-m
#8
JOURNAL ARTICLE
Hua Li, Jiafan Zhang, Ting Shao, Huifeng Wang, Sai Liu, Keli Long
PURPOSE: This study aimed to investigate the stability of posterior corneal surface 2 years after transepithelial photorefractive keratectomy (TPRK) in patients with a residual stromal thickness less than 350 μm. METHODS: In total, 408 eyes of 212 patients (160 women, 52 men) who underwent TPRK were enrolled in this retrospective study. All surgeries were performed in the Amaris 750S excimer laser platform with smart pulse technology. The posterior corneal elevation, anterior chamber depth, Q value, and curvature were measured using Pentacam preoperatively and postoperatively...
September 23, 2022: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/35634717/-in-vivo-corneal-stiffness-mapping-by-the-stress-strain-index-maps-and-brillouin-microscopy
#9
JOURNAL ARTICLE
Bernardo T Lopes, Ahmed Elsheikh
The study of corneal stiffness in vivo has numerous clinical applications such as the measurement of intraocular pressure, the preoperative screening for iatrogenic ectasia after laser vision correction surgery and the diagnosis and treatment of corneal ectatic diseases such as keratoconus. The localised aspect of the microstructure deterioration in keratoconus leading to local biomechanical softening, corneal bulging, irregular astigmatism and ultimately loss of vision boosted the need to map the corneal stiffness to identify the regional biomechanical failure...
May 30, 2022: Current Eye Research
https://read.qxmd.com/read/34448966/adverse-events-after-riboflavin-uv-a-corneal-cross-linking-a-literature-review
#10
REVIEW
Sebastiano Serrao, Giuseppe Lombardo, Marco Lombardo
BACKGROUND: Riboflavin/UV-A corneal cross-linking (CXL) for treating keratoconus and iatrogenic corneal ectasia has been well-established as first treatment option to stabilize corneal tissue biomechanical instability. Although the plethora of clinical studies has been published into the field, there is no systematic review assessing the type and frequency of adverse events after CXL. METHODS: A systemic literature review on clinical safety and adverse events after CXL in patients with keratoconus and corneal ectasia was performed using PubMed...
January 2022: International Ophthalmology
https://read.qxmd.com/read/34384340/progressive-corneal-ectatic-disease-in-pregnancy
#11
REVIEW
Devanshi Jani, James McKelvie, Stuti L Misra
Pregnancy influences ocular changes which may exacerbate existing or develop new pathology. This review summarises the existing evidence on the association between pregnancy and progressive keratoconus or iatrogenic keratectasia. Ten online databases were searched systematically. Eligible studies were published in English and reported objective ophthalmic outcomes for women with evidence of (i) a new diagnosis of keratoconus, (ii) keratoconus progression or (iii) iatrogenic keratectasia following refractive surgery; during or within one year of pregnancy...
November 2021: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://read.qxmd.com/read/33229657/advanced-epithelial-mapping-for-refractive-surgery
#12
REVIEW
Pooja Khamar, Kavita Rao, Kareeshma Wadia, Ritika Dalal, Tushar Grover, Francesco Versaci, Krati Gupta
One of the leading challenges in refractive surgery today is the presence of underlying subclinical early-stage keratoconus (KC), which can lead to iatrogenic post laser in situ keratomileusis ectasia. Timely detection of this condition could aid the refractive surgeons in better decision-making. This includes being able to defer refractive surgery in subclinical cases as well as providing treatment for the same in the form of appropriate corneal collagen crosslinking treatments. Corneal topography is considered the gold standard for the diagnosis of corneal ectatic disorders...
December 2020: Indian Journal of Ophthalmology
https://read.qxmd.com/read/32678352/a-review-of-imaging-modalities-for-detecting-early-keratoconus
#13
REVIEW
Xuemin Zhang, Saleha Z Munir, Syed A Sami Karim, Wuqaas M Munir
OBJECTIVES: Early identification of keratoconus is imperative for preventing iatrogenic corneal ectasia and allowing for early corneal collagen cross-linking treatments to potentially halt progression and decrease transplant burden. However, early diagnosis of keratoconus is currently a diagnostic challenge as there is no uniform screening criteria. We performed a review of the current literature to assess imaging modalities that can be used to help identify subclinical keratoconus. METHODS: A Pubmed database search was conducted...
January 2021: Eye
https://read.qxmd.com/read/32042837/biomechanical-diagnostics-of-the-cornea
#14
REVIEW
Louise Pellegrino Gomes Esporcatte, Marcella Q Salomão, Bernardo T Lopes, Paolo Vinciguerra, Riccardo Vinciguerra, Cynthia Roberts, Ahmed Elsheikh, Daniel G Dawson, Renato Ambrósio
Corneal biomechanics has been a hot topic for research in contemporary ophthalmology due to its prospective applications in diagnosis, management, and treatment of several clinical conditions, including glaucoma, elective keratorefractive surgery, and different corneal diseases. The clinical biomechanical investigation has become of great importance in the setting of refractive surgery to identify patients at higher risk of developing iatrogenic ectasia after laser vision correction. This review discusses the latest developments in the detection of corneal ectatic diseases...
2020: Eye and Vision (London, England)
https://read.qxmd.com/read/31598520/pentacam%C3%A2-corneal-tomography-for-screening-of-refractive-surgery-candidates-a-review-of-the-literature-part-i
#15
REVIEW
Mahsaw N Motlagh, Majid Moshirfar, Michael S Murri, David F Skanchy, Hamed Momeni-Moghaddam, Yasmyne C Ronquillo, Phillip C Hoopes
Corneal tomography and Scheimpflug imaging are frequently used to analyze the corneal surface, especially in the field of cataract and refractive surgery. The Pentacam system is one of the most commonly used commercially available systems for this purpose. Through a rotating Scheimpflug camera, the system is capable of creating a three-dimensional map of the cornea. These advances in tomography have simultaneously enhanced the ability of clinicians to screen surgical candidates and detect subtle corneal changes in diseases such as keratoconus...
2019: Medical Hypothesis, Discovery and Innovation in Ophthalmology
https://read.qxmd.com/read/31487097/corneal-refractive-surgery-combined-with-simultaneous-corneal-cross-linking-indications-protocols-and-clinical-outcomes-a-review
#16
REVIEW
Jiaonan Ma, Yan Wang, Vishal Jhanji
Corneal refractive surgery is one of the most common approaches for correction of refractive errors. Combined corneal refractive surgery and corneal cross-linking (CXL) has been proposed as a method to achieve better refractive stability and to prevent iatrogenic corneal ectasia. However, there are concerns regarding its indications, surgical safety, standardization of protocols and long-term effect on corneal tissue. This review article aims to discuss the current knowledge and recent updates on combination of CXL and refractive surgery...
September 5, 2019: Clinical & Experimental Ophthalmology
https://read.qxmd.com/read/31411927/review-of-laser-vision-correction-lasik-prk-and-smile-with-simultaneous-accelerated-corneal-crosslinking-long-term-results
#17
REVIEW
Elizabeth Wen Ling Lim, Li Lim
Purpose : Laser in-situ keratomileusis (LASIK), photorefractive keratectomy (PRK) and small-incision lenticule extraction (SMILE) are safe and effective refractive surgical procedures. However, complications include regression of treatment and iatrogenic keratectasia which can be severe and sight-threatening. In order to reduce these complications, simultaneous corneal cross-linking (CXL) is currently being added to these refractive procedures. This review analyses current long-term literature (≥ 1 year follow-up) on refractive surgery and simultaneous CXL (LASIK Xtra, PRK Xtra and SMILE Xtra) to determine its overall safety and efficacy...
November 2019: Current Eye Research
https://read.qxmd.com/read/30312535/chronic-rejection-of-human-face-allografts
#18
JOURNAL ARTICLE
Nicco Krezdorn, Christine G Lian, Michael Wells, Luccie Wo, Sotirios Tasigiorgos, Shuyun Xu, Thiago J Borges, Rayven M Frierson, Ewelina Stanek, Leonardo V Riella, Bohdan Pomahac, George F Murphy
Face vascularized composite allografts (FVCAs) have helped patients with severe facial disfigurement, with acute rejection now largely controlled through iatrogenic immunosuppression. However, little is known regarding the incidence and mechanism(s) of more long-term pathologic alterations in FVCAs that may affect function and graft durability. Protocol surveillance biopsy specimens for up to an 8-year interval in 7 patients who received FVCAs at our institution revealed histopathologic evidence of chronic rejection...
October 12, 2018: American Journal of Transplantation
https://read.qxmd.com/read/30123381/review-of-corneal-biomechanical-properties-following-lasik-and-smile-for-myopia-and-myopic-astigmatism
#19
REVIEW
Iben Bach Damgaard, Mohamed Reffat, Jesper Hjortdal
Worldwide, femtosecond Laser Assisted In-situ Keratomileusis (LASIK) is a well known and commonly used refractive technique, although Small Incision Lenticule Extraction (SMILE) has become increasingly popular since it was introduced in 2011. In LASIK, a corneal flap is cut with a microkeratome or femtosecond laser, followed by thinning of the stromal bed with excimer laser ablation. In SMILE, a minor intrastromal lenticule is cut with a femtosecond laser and subsequently removed through a small incision, leaving the anterior and strongest part of the cornea almost intact...
2018: Open Ophthalmology Journal
https://read.qxmd.com/read/29750010/comparative-analysis-of-safety-and-efficacy-of-photorefractive-keratectomy-versus-photorefractive-keratectomy-combined-with-crosslinking
#20
JOURNAL ARTICLE
Gitansha Shreyas Sachdev, Shreyas Ramamurthy, Ramamurthy Dandapani
Purpose: To assess the safety, efficacy, and refractive predictability of half-fluence accelerated corneal collagen crosslinking (CXL) applied concurrently with photorefractive keratectomy (PRK), and compare the results to standard PRK. Setting: Refractive Services, The Eye Foundation, Coimbatore, India. Design: Interventional comparative case series. Methods: Patients seeking refractive correction for myopia or myopic astigmatism were included in the study...
2018: Clinical Ophthalmology
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