Yan Wang, Cong Li, Lei Liu, Yuan Yang, Xue He, Gang Li, Xianzhen Zheng, Yun Ren, Hanpeng Zhao, Zhenchao Du, Jianrong Jiang, Yu Kuang, Fujun Jia, Honghua Yu, Xiaohong Yang
BACKGROUND: Identifying the fundus objective biomarkers for the major depressive disorders (MDD) may help promote mental health. The aim of this study was to evaluate retinal neurovascular changes and further investigate their association with disease severity in MDD. METHODS: This cross-sectional study conducted in the hospital enrolled patients with MDD and healthy controls.The retinal neurovascular parameters for all subjects, including vessel density (VD), thickness of ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL), and optic nerve head (ONH) eg are automatically calculated by the software in optical coherence tomography angiography (OCTA)...
2024: Psychology Research and Behavior Management