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https://www.readbyqxmd.com/read/28534844/property-analysis-of-the-real-time-uncalibrated-phase-delay-product-generated-by-regional-reference-stations-and-its-influence-on-precise-point-positioning-ambiguity-resolution
#1
Yong Zhang, Qing Wang, Xinyuan Jiang
The real-time estimation of the wide-lane and narrow-lane Uncalibrated Phase Delay (UPD) of satellites is realized by real-time data received from regional reference station networks; The properties of the real-time UPD product and its influence on real-time precise point positioning ambiguity resolution (RTPPP-AR) are experimentally analyzed according to real-time data obtained from the regional Continuously Operating Reference Stations (CORS) network located in Tianjin, Shanghai, Hong Kong, etc. The results show that the real-time wide-lane and narrow-lane UPD products differ significantly from each other in time-domain characteristics; the wide-lane UPDs have daily stability, with a change rate of less than 0...
May 19, 2017: Sensors
https://www.readbyqxmd.com/read/28487534/operando-sxrd-study-of-the-structure-and-growth-process-of-cu2s-ultra-thin-films
#2
Andrea Giaccherini, Serena Cinotti, Annalisa Guerri, Francesco Carlà, Giordano Montegrossi, Francesco Vizza, Alessandro Lavacchi, Roberto Felici, Francesco Di Benedetto, Massimo Innocenti
Electrochemical Atomic Layer Deposition (E-ALD) technique has demonstrated to be a suitable process for growing compound semiconductors, by alternating the under-potential deposition (UPD) of the metallic element with the UPD of the non-metallic element. The cycle can be repeated several times to build up films with sub-micrometric thickness. We show that it is possible to grow, by E-ALD, Cu2S ultra-thin films on Ag(111) with high structural quality. They show a well ordered layered crystal structure made on alternating pseudohexagonal layers in lower coordination...
May 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28478949/imprinted-disorders-and-growth
#3
Éloïse Giabicani, Frédéric Brioude, Yves Le Bouc, Irène Netchine
Fetal growth is a complex process. Its restriction is associated with morbidity and long-term metabolic consequences. Imprinted genes have a critical role in mammalian fetal growth. Beckwith-Wiedemann syndrome (BWS) and Silver-Russell syndrome (SRS) are two imprinting disorders with opposite fetal growth disturbance. SRS is leading to severe fetal and postnatal growth retardation with severe feeding difficulties during early childhood and long-term metabolic consequences and BWS is an overgrowth syndrome with an enhanced risk of tumors during childhood...
May 4, 2017: Annales D'endocrinologie
https://www.readbyqxmd.com/read/28458213/decapitation-improves-the-efficiency-of-cd-phytoextraction-by-celosia-argentea-linn
#4
Jie Liu, Xuehong Zhang, Lingyun Mo, Shiyin Yao, Yixuan Wang
The effect of decapitation on enhancing plant growth and Cd accumulation in Celosia argentea Linn. was evaluated using a pot experiment. Decapitation significantly enhanced the growth of C. argentea. The numbers of branch and leaf in the decapitated plants (DP) were significantly higher than those in undecapitated plants (UDP, p < 0.05). Decapitation increased the biomass by 75%-105% for roots, 108%-152% for stems, and 80%-107% for leaves. Although the transpiration and photosynthesis rates were not significantly different between DP and UPD, decapitation significantly increased the total leaf area and total transpiration per plant (p < 0...
April 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28449579/enhanced-kinetics-of-electrochemical-hydrogen-uptake-and-release-on-palladium-powders-modified-by-electrochemical-atomic-layer-deposition
#5
David Michael Benson, Chu Tsang, Joshua D Sugar, Kaushik Jagannathan, David B Robinson, Farid El Gabaly, Patrick J Cappillino, John L Stickney
Electrochemical atomic layer deposition (E-ALD) is a method for the formation of nanofilms of materials, an atomic layer at a time. It uses the galvanic exchange of a less noble metal, deposited by underpotential deposition (UPD), to produce an atomic layer of a more noble element by reduction of its ions. This process is referred to as surface limited redox replacement (SLRR), and can be repeated in a cycle to grow thicker deposits. It was previously performed on nanoparticles and planar substrates. In the present report, E-ALD has been applied to coating a sub-micron sized powder substrate, making use of a new flow cell design...
April 28, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28448384/cytoreductive-surgery-for-metastatic-gastrointestinal-stromal-tumors-treated-with-tyrosine-kinase-inhibitors-a-2-institutional-analysis
#6
Mark Fairweather, Vinod P Balachandran, George Z Li, Monica M Bertagnolli, Cristina Antonescu, William Tap, Samuel Singer, Ronald P DeMatteo, Chandrajit P Raut
OBJECTIVE: To refine treatment recommendations for patients with metastatic gastrointestinal stromal tumors (GISTs) treated with tyrosine kinase inhibitors (TKIs) and surgery. BACKGROUND: Early reports suggested that patients with metastatic GIST responding to TKIs treated with surgery may have favorable outcomes. However, identification of prognostic factors was limited by small cohorts. METHODS: Progression-free survival (PFS) and overall survival (OS) from time of surgery and from start of initial TKI was determined...
April 26, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28428536/real-time-observation-of-interfacial-ions-during-electrocrystallization
#7
Masashi Nakamura, Takahiro Banzai, Yuto Maehata, Osamu Endo, Hiroo Tajiri, Osami Sakata, Nagahiro Hoshi
Understanding the electrocrystallization mechanisms of metal cations is of importance for many industrial and scientific fields. We have determined the transitional structures during underpotential deposition (upd) of various metal cations on Au(111) electrode using time-resolved surface X-ray diffraction and step-scan IR spectroscopy. At the initial stage of upd, a characteristic intensity transient appears in the time-resolved crystal truncation rod depending on metal cations. Metal cations with relatively high coordination energies of hydration water are deposited in two steps: first, the hydrated metal cations approached the surface and are metastably located at the outer Helmholtz plane, then they are deposited via the destruction of the hydration shell...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28418651/electrodeposition-of-highly-porous-pt-nanoparticles-studied-by-quantitative-3d-electron-tomography-influence-of-growth-mechanisms-and-potential-cycling-on-the-active-surface-area
#8
Jon Ustarroz, Bart Geboes, Hans Vanrompay, Kadir Sentosun, Sara Bals, Tom Breugelmans, Annick Hubin
Nanoporous Pt nanoparticles (NPs) are promising fuel cell catalysts due to their large surface area and increased electrocatalytic activity toward the oxygen reduction reaction (ORR). Herein, we report on the influence of the growth mechanisms on the surface properties of electrodeposited Pt dendritic NPs with large surface areas. The electrochemically active surface was studied by hydrogen underpotential deposition (H UPD) and compared for the first time to high-angle annular dark field scanning transmission electron microscopy (HAADF-STEM) quantitative 3D electron tomography of individual nanoparticles...
May 3, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28391680/stoichiometry-morphology-and-size-controlled-electrochemical-fabrication-of-cuxo-x-1-2-at-underpotential
#9
Cemile Kartal, Yeşim Hanedar, Tuba Öznülüer, Ümit Demir
A new one-step electrochemical approach has been developed for the morphology, size, and stoichiometry-controlled synthesis of Cu2O, CuO, and Cu2O/CuO composite structures at room temperature without using surfactants, capping agents, or any other additives. The electrochemical deposition of a Cu monolayer using underpotential deposition (UPD) and the flow rate of oxygen gas bubbled through the deposition solution used for oxidation of the Cu layer are the key parameters for controlling the stoichiometry of the CuxO (x = 1, 2) structures...
April 14, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28264487/investigating-autism-related-symptoms-in-children-with-prader-willi-syndrome-a-case-study
#10
Jeffrey A Bennett, Sandra Hodgetts, Michelle L Mackenzie, Andrea M Haqq, Lonnie Zwaigenbaum
Prader-Willi syndrome (PWS), a rare genetic disorder caused by the lack of expression of paternal genes from chromosome 15q11-13, has been investigated for autism spectrum disorder (ASD) symptomatology in various studies. However, previous findings have been variable, and no studies investigating ASD symptomatology in PWS have exclusively studied children. We aimed to characterize social communication functioning and other ASD-related symptoms in children with PWS, and assessed agreement across measures and rates of ASD diagnosis...
February 28, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28246213/growth-control-in-the-drosophila-eye-disc-by-the-cytokine-unpaired
#11
Jannik Vollmer, Patrick Fried, Daniel Aguilar-Hidalgo, Máximo Sánchez-Aragón, Antonella Iannini, Fernando Casares, Dagmar Iber
A fundamental question in developmental biology is how organ size is controlled. We have previously shown that the area growth rate in the Drosophila eye primordium declines inversely proportionally to the increase in its area. How the observed reduction in the growth rate is achieved is unknown. Here, we explore the dilution of the cytokine Unpaired (Upd) as a possible candidate mechanism. In the developing eye, upd expression is transient, ceasing at the time when the morphogenetic furrow first emerges. We confirm experimentally that the diffusion and stability of the JAK/STAT ligand Upd are sufficient to control eye disc growth via a dilution mechanism...
March 1, 2017: Development
https://www.readbyqxmd.com/read/28230753/formal-uncertainty-and-dispersion-of-single-and-double-difference-models-for-gnss-based-attitude-determination
#12
Wen Chen, Chao Yu, Danan Dong, Miaomiao Cai, Feng Zhou, Zhiren Wang, Lei Zhang, Zhengqi Zheng
With multi-antenna synchronized global navigation satellite system (GNSS) receivers, the single difference (SD) between two antennas is able to eliminate both satellite and receiver clock error, thus it becomes necessary to reconsider the equivalency problem between the SD and double difference (DD) models. In this paper, we quantitatively compared the formal uncertainties and dispersions between multiple SD models and the DD model, and also carried out static and kinematic short baseline experiments. The theoretical and experimental results show that under a non-common clock scheme the SD and DD model are equivalent...
February 20, 2017: Sensors
https://www.readbyqxmd.com/read/28199302/untimely-expression-of-gametogenic-genes-in-vegetative-cells-causes-uniparental-disomy
#13
H Diego Folco, Venkata R Chalamcharla, Tomoyasu Sugiyama, Gobi Thillainadesan, Martin Zofall, Vanivilasini Balachandran, Jothy Dhakshnamoorthy, Takeshi Mizuguchi, Shiv I S Grewal
Uniparental disomy (UPD), in which an individual contains a pair of homologous chromosomes originating from only one parent, is a frequent phenomenon that is linked to congenital disorders and various cancers. UPD is thought to result mostly from pre- or post-zygotic chromosome missegregation. However, the factors that drive UPD remain unknown. Here we use the fission yeast Schizosaccharomyces pombe as a model to investigate UPD, and show that defects in the RNA interference (RNAi) machinery or in the YTH domain-containing RNA elimination factor Mmi1 cause high levels of UPD in vegetative diploid cells...
March 2, 2017: Nature
https://www.readbyqxmd.com/read/28197627/copy-number-analysis-identifies-tumor-suppressive-lncrnas-in-human-osteosarcoma
#14
Jianjun Xie, Dechen Lin, Dhong Hyun Tony Lee, Jennifer Akunowicz, Marc Hansen, Carl Miller, Masashi Sanada, Motohiro Kato, Tadayuki Akagi, Norihiko Kawamata, Seishi Ogawa, H Phillip Koeffler
Osteosarcoma (OS) has a high degree of chromosomal instability and total copy number (CN) changes. We examined 58 human OS samples including 40 primary tumors, 11 explants, and 7 cell lines using single nucleotide polymorphism (SNP) arrays, and revealed that 70% of the samples had one or more recurrent CN-neutral loss of heterozygosity (CNN‑LOH) also known as uniparental disomy (UPD). Importantly, 17% of the samples showed prominent homozygous deletion of 3q13.31, suggesting its role in tumorigenesis. We identified and characterized two novel lncRNAs, LOC285194 and BC040587, within this genomic locus, strongly suggesting their tumor suppressor activity...
March 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28157578/chromosomal-uniparental-disomy-16-and-fetal-intrauterine-growth-restriction
#15
Xie Yingjun, Hu Zhiyang, Lin Linhua, Su Fangming, Huang Linhuan, Tan Jinfeng, Pang Qianying, Sun Xiaofang
BACKGROUND: There is a well-documented association between prenatally diagnosed chromosomal uniparental disomy and poor pregnancy outcome. METHODS AND RESULT: In this study, we identified an intrauterine growth restricted fetus carrying a maternal UPD 16 with segmental hetero- and isodisomy using the Affymetrix CytoScan HD SNP-array and the UPDtool. We also performed FISH to exclude trisomy mosaicism of chr.16. We then explored the genetic mechanisms of how imprinted genes cause clinical abnormalities...
December 23, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28124401/brca1-alterations-with-additional-defects-in-dna-damage-response-genes-may-confer-chemoresistance-to-brca-like-breast-cancers-treated-with-neoadjuvant-chemotherapy
#16
Mamoru Takada, Shigenori Nagai, Masayuki Haruta, Ryuichi P Sugino, Katsunori Tozuka, Hiroyuki Takei, Fumie Ohkubo, Kenichi Inoue, Masafumi Kurosumi, Masaru Miyazaki, Aiko Sato-Otsubo, Yusuke Sato, Seishi Ogawa, Yasuhiko Kaneko
The BRCA-like phenotype is a feature that some sporadic breast cancers share with those occurring in BRCA1 or BRCA2 mutation carriers. As tumors with the phenotype have defects in the DNA damage response pathway, which may increase sensitivity to drugs such as DNA cross-linking agents and PARP inhibitors, a method to identify this phenotype is important. The prediction of chemoresistance, which frequently develops in these tumors, is also crucial for improving therapy. We examined genomic aberrations and BRCA1 promoter methylation in tumors of 73 breast cancer (20 HR-/HER2- and 53 HR+/HER2-) patients, who received neoadjuvant chemotherapy with anthracycline, cyclophosphamide, and taxane, using SNP array CGH and quantitative PCR...
May 2017: Genes, Chromosomes & Cancer
https://www.readbyqxmd.com/read/28076762/a-leptin-analog-locally-produced-in-the-brain-acts-via-a-conserved-neural-circuit-to-modulate-obesity-linked-behaviors-in-drosophila
#17
Jennifer Beshel, Josh Dubnau, Yi Zhong
Leptin, a typically adipose-derived "satiety hormone," has a well-established role in weight regulation. Here we describe a functionally conserved model of genetically induced obesity in Drosophila by manipulating the fly leptin analog unpaired 1 (upd1). Unexpectedly, cell-type-specific knockdown reveals upd1 in the brain, not the adipose tissue, mediates obesity-related traits. Disrupting brain-derived upd1 in flies leads to all the hallmarks of mammalian obesity: increased attraction to food cues, increased food intake, and increased weight...
January 10, 2017: Cell Metabolism
https://www.readbyqxmd.com/read/28032876/evaluaci%C3%A3-n-de-las-evidencias-y-calidad-de-las-gu%C3%A3-as-de-pr%C3%A3-ctica-cl%C3%A3-nica-sobre-deterioro-de-la-integridad-cut%C3%A3-nea-%C3%A3%C2%BAlceras-y-heridas-cr%C3%A3-nicas
#18
J M Rumbo Prieto, M Romero Martín, D Bellido Guerrero, L Arantón Areosa, C D Raña Lama, F Palomar Llatas
Fundamento. La situación epidemiológica, sociosanitaria y económica que rodea al deterioro de la integridad cutánea supone un gran problema para el sistema sanitario. Su prevención y tratamiento crea incertidumbre y variabilidad profesional siendo prioritario contar con buenas Guías de Práctica Clínica (GPC). El objetivo fue conocer la calidad de las GPC sobre prevención y tratamiento de úlceras por presión (UPP), úlceras venosas de la pierna (UVP) y úlceras de pie diabético (UPD). Metodología...
December 30, 2016: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/28032339/maternal-uniparental-disomy-of-chromosome-16-upd-16-mat-clinical-features-are-rather-caused-by-hidden-trisomy-16-mosaicism-than-by-upd-16-mat-itself
#19
Ruth Scheuvens, Matthias Begemann, Lukas Soellner, Dieter Meschede, Gisela Raabe-Meyer, Miriam Elbracht, Regine Schubert, Thomas Eggermann
Maternal uniparental disomy of chromosome 16 (upd(16)mat) as the result of trisomy 16 is one of the most frequently reported uniparental disomies in humans, but a consistent phenotype is not obvious. Particularly, it is difficult to discriminate between features resulting from upd(16)mat and mosaic trisomy 16. By evaluating literature data (n = 74) and three own cases we aimed to determine whether the clinical features are due to upd(16)mat or to trisomy 16 mosaicism. Whereas in single cases the clinical symptoms were caused by homozygosity of autosomal recessive mutations on chromosome 16, it turned out that clinical features in upd(16)mat are caused by (hidden) trisomy 16 mosaicism and a specific chromosome 16 associated imprinting disorder does not exist...
December 29, 2016: Clinical Genetics
https://www.readbyqxmd.com/read/27980747/mosaic-partial-pericentromeric-trisomy-8-and-maternal-uniparental-disomy-in-a-male-patient-with-autism-spectrum-disorder
#20
Dina F Ahram, Danae Stambouli, Aleksandra Syrogianni, Yasser Al-Sarraj, Spyridon Gerou, Hatem El-Shanti, Marios Kambouris
Various chromosomal anomalies including small supernumerary marker chromosome (sSMC) and Uniparental disomy (UPD) have been described in association with intellectual disability and autism spectrum disorder. Based on our reported findings, we recommend that patients with sSMC(8) be evaluated for autism spectrum disorder (ASD) for early institution of therapy. In the presence of an identifiable sSMC, exploration of UPD is also recommended to further investigate the role of chromosome 8 UPD in ASD.
December 2016: Clinical Case Reports
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