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Alexandre Perez-Girbes, Gregor M Dunham, Ken F Linnau
This is the installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at .
October 24, 2016: Emergency Radiology
Nupur Verma, John D Pham, Ken F Linnau
This is the 21st installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at .
October 18, 2016: Emergency Radiology
Haixuan Yang, Cathal Seoighe
Nonnegative Matrix Factorization (NMF) has proved to be an effective method for unsupervised clustering analysis of gene expression data. By the nonnegativity constraint, NMF provides a decomposition of the data matrix into two matrices that have been used for clustering analysis. However, the decomposition is not unique. This allows different clustering results to be obtained, resulting in different interpretations of the decomposition. To alleviate this problem, some existing methods directly enforce uniqueness to some extent by adding regularization terms in the NMF objective function...
2016: PloS One
Laura Calió, Samrana Kazim, Michael Grätzel, Shahzada Ahmad
The pressure to move towards renewable energy has inspired researchers to look for ideas in photovoltaics that may lead to a major breakthrough. Recently the use of perovskites as a light harvester has lead to stunning progress. The power conversion efficiency of perovskite solar cells is now approaching parity (>22 %) with that of the established technology which took decades to reach this level of performance. The use of a hole transport material (HTM) remains indispensable in perovskite solar cells...
October 14, 2016: Angewandte Chemie
Xiaowen Chang, Weiping Li, Haining Chen, Liqun Zhu, Huicong Liu, Huifang Geng, Sisi Xiang, Jiaming Liu, Xiaoli Zheng, Ying-Long Yang, Shihe Yang
Carbon-based hole transport materials (HTM)-free perovskite solar cells (PSCs) due to their relatively high stability have attracted intense attention. However, their power conversion efficiency (PCE) is still low, especially for the simplest paintable carbon-based PSCs (C-PSCs), whose performance is greatly limited by the poor contact at perovskite/carbon interface. To enhance interface contact, it is important to fabricate an even-surface perovskite layer in porous scaffold, which is usually unfeasible due to rough crystal precursor...
October 14, 2016: ACS Applied Materials & Interfaces
Aravind Chandrasekaran, Justin Chan, Carmay Lim, Lee-Wei Yang
Structure-encoded conformational dynamics are crucial for biomolecular functions. However, there is insufficient evidence to support the notion that dynamics plays a role in guiding protein-nucleic acid interactions. Here, we show that protein-DNA docking orientation is a function of protein intrinsic dynamics but the binding site itself does not display unique patterns in the examined spectrum of motions. This revelation is made possible by a novel technique that locates 'dynamics interfaces' in proteins across which protein parts are anti-correlated in their slowest dynamics...
October 10, 2016: Journal of Chemical Theory and Computation
Yi Zhang, Peng Gao, Emad Oveisi, Yonghui Lee, Quentin Jeangros, Giulia Grancini, Sanghyun Paek, Yaqing Feng, Mohammad Khaja Nazeeruddin
Interfacial engineering of the meso-TiO2 surface through a modified sequential deposition procedure involving a novel PbI2-HMPA complex pretreatment is conducted as a reproducible method for preparing MAPbI3-based perovskite solar cells providing the highest efficiencies yet reported with polymer HTM layer. Grazing incidence X-ray diffraction depth profiling confirms the formation of a perovskite film with PbI2-rich region close to the electron transport layer (ETL) due to the strong interaction of HMPA with PbI2, which successfully retarded the dissolution of PbI2 phase when depositing the perovskite layer on top...
October 10, 2016: Journal of the American Chemical Society
(no author information available yet)
The current issue of MMWR (week 39) will be the last to include data from the 122 Cities Mortality Reporting System (122 CMRS) in Notifiable Disease and Mortality Tables, Table III ("Deaths in 122 cities" []). Beginning in the publication for the week ending October 8, 2016 (week 40), data from the National Center for Health Statistics (NCHS) Mortality Surveillance System will replace the information reported in Table III, and the 122 Cities Mortality Reporting System (122 CMRS) will be retired...
October 7, 2016: MMWR. Morbidity and Mortality Weekly Report
Hsin-Wei Chen, Tzu-Yen Huang, Ting-Hsiang Chang, Yoshitaka Sanehira, Chung-Wei Kung, Chih-Wei Chu, Masashi Ikegami, Tsutomu Miyasaka, Kuo-Chuan Ho
In this study, hybrid perovskite solar cells are fabricated using poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) and poly(3-hexylthiophene-2,5-diyl) (P3HT) as dopant-free hole-transporting materials (HTMs), and two solution processes (one- and two-step methods, respectively) for preparing methylammonium lead iodide perovskite. By optimizing the concentrations and solvents of MEH-PPV solutions, a power conversion efficiency of 9.65% with hysteresis-less performance is achieved, while the device with 2,2',7,7'-tetrakis(N,N-di-p-methoxyphenylamine)-9,9'spirobifluorene (Spiro-OMeTAD) doped with lithium salts and tert-butylpyridine (TBP) exhibits an efficiency of 13...
October 4, 2016: Scientific Reports
Wei Xiong, Michael R Phillips
The following document is a translation of the 2015-2020 National Mental Health Work Plan of the People's Republic of China which was issued by the General Office of China's State Council on June 4, 2015. The original Chinese version of the document is available at the official government website: The translators have added annotations at the end of the document that provide background information to help contextualize content that may be unclear to readers unfamiliar with China and explain their decisions when translating terms that can have multiple interpretations...
February 25, 2016: Shanghai Archives of Psychiatry
A Ichida, K Hasegawa, T Takayama, H Kudo, Y Sakamoto, S Yamazaki, Y Midorikawa, T Higaki, Y Matsuyama, N Kokudo
BACKGROUND: Previous RCTs have failed to demonstrate the usefulness of combining energy devices with the conventional clamp crushing method to reduce blood loss during liver transection. Here, the combination of an ultrasonically activated device (UAD) and a bipolar vessel-sealing device (BVSD) with crush clamping was investigated. METHODS: Patients scheduled to undergo hepatectomy at the University of Tokyo Hospital or Nihon University Itabashi Hospital were eligible for this parallel-group, single-blinded randomized study...
September 29, 2016: British Journal of Surgery
Alessandro Lorenzo Palma, Lucio Cinà, Yan Busby, Andrea Marsella, Antonio Agresti, Sara Pescetelli, Jean-Jacques Pireaux, Aldo Di Carlo
Solution-processed hybrid bromide perovskite light-emitting-diodes (PLEDs) represent an attractive alternative technology that would allow overcoming the well-known severe efficiency drop in the green spectrum related to conventional LEDs technologies. In this work, we report on the development and characterization of PLEDs fabricated using, for the first time, a mesostructured layout. Stability of PLEDs is a critical issue; remarkably, mesostructured PLEDs devices tested in ambient conditions and without encapsulation showed a lifetime well-above what previously reported with a planar heterojunction layout...
October 3, 2016: ACS Applied Materials & Interfaces
Xi Chen, Xu Shi, Leena Hilakivi-Clarke, Ayesha N Shajahan-Haq, Robert Clarke, Jianhua Xuan
MOTIVATION: Whole genome DNA-sequencing (WGS) of paired tumor and normal samples has enabled the identification of somatic DNA changes in an unprecedented detail. Large-scale identification of somatic structural variations (SVs) for a specific cancer type will deepen our understanding of driver mechanisms in cancer progression. However, the limited number of WGS samples, insufficient read coverage, and the impurity of tumor samples that contain normal and neoplastic cells, limit reliable and accurate detection of somatic SVs...
September 21, 2016: Bioinformatics
F Mike Busdicker
No abstract text is available yet for this article.
September 2016: Biomedical Instrumentation & Technology
Axel Wirth
No abstract text is available yet for this article.
September 2016: Biomedical Instrumentation & Technology
Ajay K Baranwal, Shusaku Kanaya, T A Nirmal Peiris, Gai Mizuta, Tomoya Nishina, Hiroyuki Kanda, Tsutomu Miyasaka, Hiroshi Segawa, Seigo Ito
Many efforts have been made towards improving perovskite (PVK) solar cell stability, but their thermal stability, particularly at 85 °C (IEC 61646 climate chamber tests), remains a challenge. Outdoors, the installed solar cell temperature can reach up to 85 °C, especially in desert regions, providing sufficient motivation to study the effect of temperature stress at or above this temperature (e.g., 100 °C) to confirm the commercial viability of PVK solar cells for industrial companies. In this work, a three-layer printable HTM-free CH3 NH3 PbI3 PVK solar cell with a mesoporous carbon back contact and UV-curable sealant was fabricated and tested for thermal stability over 1500 h at 100 °C...
September 22, 2016: ChemSusChem
Yuwei Cui, Subutar Ahmad, Jeff Hawkins
The ability to recognize and predict temporal sequences of sensory inputs is vital for survival in natural environments. Based on many known properties of cortical neurons, hierarchical temporal memory (HTM) sequence memory recently has been proposed as a theoretical framework for sequence learning in the cortex. In this letter, we analyze properties of HTM sequence memory and apply it to sequence learning and prediction problems with streaming data. We show the model is able to continuously learn a large number of variableorder temporal sequences using an unsupervised Hebbian-like learning rule...
September 14, 2016: Neural Computation
Xiao Wang, Jinghua Gu, Leena Hilakivi-Clarke, Robert Clarke, Jianhua Xuan
MOTIVATION: The advent of high-throughput DNA methylation profiling techniques has enabled the possibility of accurate identification of differentially methylated genes for cancer research. The large number of measured loci facilitates whole genome methylation study, yet posing great challenges for differential methylation detection due to the high variability in tumor samples. RESULTS: We have developed a novel probabilistic approach, DM-BLD, to detect differentially methylated genes based on a Bayesian framework...
September 11, 2016: Bioinformatics
Kelly Michelson, Marla L Clayman, Claire Ryan, Linda Emanuel, Joel Frader
While there is a robust literature describing family conferences (FCs) in adult intensive care units (ICUs), less information exists about FCs in pediatric ICUs (PICUs). We conducted a pilot study to describe the focus of discussion, communication patterns of health care team members (HTMs) and parents, and parents' perspectives about clinician communication during PICU FCs. We analyzed data from 22 video- or audiorecorded PICU FCs and post-FC questionnaire responses from 27 parents involved in 18 FCs. We used the Roter Interaction Analysis System (RIAS) to describe FC dialogue content...
September 9, 2016: Health Communication
M Ikeda, S Shimizu, T Sato, M Morimoto, Y Kojima, Y Inaba, A Hagihara, M Kudo, S Nakamori, S Kaneko, R Sugimoto, T Tahara, T Ohmura, K Yasui, K Sato, H Ishii, J Furuse, T Okusaka
BACKGROUND: Sorafenib (Sor) is acknowledged as a standard therapy for advanced hepatocellular carcinoma (HCC). This trial was conducted to evaluate the effect of addition of hepatic arterial infusion chemotherapy with cisplatin (SorCDDP) to Sor for the treatment of advanced HCC. PATIENTS AND METHODS: We conducted a multicenter open-labeled randomized phase II trial in chemo-naïve patients with advanced HCC with Child-Pugh scores of 5-7. Eligible patients were randomly assigned 2:1 to receive SorCDDP (sorafenib: 400 mg bid; cisplatin: 65 mg/m(2), day 1, every 4-6 weeks) or Sor (400 mg bid)...
August 29, 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
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