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https://www.readbyqxmd.com/read/28636771/is-transvaginal-contained-tissue-extraction-for-everyone
#1
Charles Miller
Professor Ghezzi, et al. should be congratulated for their excellent manuscript "Transvaginal Contained Tissue Extraction After Laparoscopic Myomectomy: A Cohort Study". This is a well-conceived, well-written retrospective cohort study describing operative and peri-operative outcomes for patients who have undergone transvaginal morcellation via a posterior colpotomy. Given the continued controversy regarding electronic power morcellation leading to restriction of use in certain areas, this study is not only impactful, in that it describes an alternative technique with data accumulated over a decade of experience, but it describes a technique of contained morcellation that is neither based on the controversial power morcellation, nor the mini-laparotomy (https://www...
June 21, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28625600/where-to-do-water-testing-for-pseudomonas-aeruginosa-in-a-healthcare-setting
#2
Mark I Garvey, Craig W Bradley, Elisabeth Holden, Mike Weibren
Pseudomonas aeruginosa is an important nosocomial pathogen commonly colonising hospital water supplies. HTM 04-01 addresses the risk posed by recommending water testing in augmented care areas which includes outpatient haemodialysis. We discuss how two teaching hospitals independently reviewed the risk to outpatient haemodialysis patients drawing the same conclusion. The highest number of infection episodes with P. aeruginosa was seen in critical care followed by burns and haematology with the lowest in haemodialysis...
June 15, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28609185/discovery-and-preclinical-development-of-netarsudil-a-novel-ocular-hypotensive-agent-for-the-treatment-of-glaucoma
#3
Cheng-Wen Lin, Bryan Sherman, Lori A Moore, Carmen L Laethem, Da-Wen Lu, Padmanabhan P Pattabiraman, Ponugoti Vasantha Rao, Mitchell A deLong, Casey C Kopczynski
PURPOSE: Rho-associated protein kinase (ROCK) inhibitors lower intraocular pressure (IOP) by increasing aqueous outflow through the trabecular meshwork (TM). The preclinical characterization of netarsudil, a new ROCK/norepinephrine transporter (NET) inhibitor currently in clinical development, is presented herein. METHODS: The kinase inhibitory activity of netarsudil was compared to its esterase metabolite, netarsudil-M1, and 3 other ROCK inhibitors using a commercially available kinase assay kit...
June 13, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28593330/core-curriculum-illustration-pediatric-viral-parotitis
#4
Barbara Pawley, Sibi Rajendran, Ramya Kondaveeti
This is the 36th installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at http://www.aseronline.org/curriculum/toc.htm .
June 7, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28586796/functional-activity-of-matrix-metalloproteinases-2-and-9-in-tears-of-patients-with-glaucoma
#5
Prity Sahay, Aparna Rao, Debananda Padhy, Sarada Sarangi, Gopinath Das, Mamatha M Reddy, Rahul Modak
Purpose: To evaluate the differential expression of tear matrix metalloproteinases (MMP) 2 and 9 in of patients with various forms of glaucoma. Methods: Tear samples were collected with a Schirmer's strip from 148 eyes of 113 patients (medically naïve patients with primary open-angle [POAG] or angle closure glaucoma [PACG] and those with pseudoexfoliation syndrome [PXF] or glaucoma [PXG]). These were compared to patients undergoing cataract surgery (controls) for this cross-sectional study...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28577249/progeny-production-in-the-periplasm-of-thermosipho-globiformans
#6
Tomohiko Kuwabara, Kensuke Igarashi
Thermotogales are rod-shaped, Gram-negative, anaerobic, (hyper) thermophiles distinguished by an outer sheath-like toga, which comprises an outer membrane (OM) and an amorphous layer (AL). Thermosipho globiformans bacteria can transform into spheroids with multiple cells concurrently with AL disintegration during early growth; the cell is defined as the cytoplasmic membrane (CM) plus the entity surrounded by the CM. Spheroids eventually produce rapidly moving periplasmic 'progenies' through an unknown mechanism...
July 2017: Extremophiles: Life Under Extreme Conditions
https://www.readbyqxmd.com/read/28567585/core-curriculum-illustration-ventriculitis-as-a-complication-of-ventriculoperitoneal-shunt-induced-rectal-perforation
#7
Barbara Pawley, Sibi Rajendran
This is the 35th installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at: http://www.aseronline.org/curriculum/toc.htm .
May 31, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28550495/core-curriculum-illustration-acute-traumatic-aortic-injury
#8
Manuel Trevino, Shaked Laks, Noemi Brunner
This is the 34th installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at http://www.aseronline.org/curriculum/toc.htm .
May 26, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28546802/immunohistochemical-evaluation-of-oestrogen-receptors-%C3%AE-and-%C3%AE-in-epithelium-of-the-vaginal-mucous-membrane-in-women-after-oestrogen-therapy
#9
Beata Sawczuk, Maria Gołębiewska, Andrzej Mazurek, Lech Chyczewski
Oestrogens act on target cells through α and β receptors (ERα and ERβ). Expression of oestrogen receptors is associated with the age and menopausal condition of women. The aim of the study was an immunohistochemical evaluation of ERα and ERβ receptors in epithelium of the vaginal mucous membrane of women subjected to different forms of hormonal therapy (HTM). Oestrogen receptors ERα and ERβ were identified using immunohistochemical methods and evaluated in smears of vaginal mucous membranes collected from 60 patients subjected to HTM (including 20 patients after oral therapy, 20 patients after transdermal therapy, and 20 patients after vaginal therapy)...
March 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/28540970/nanostructural-and-photo-electrochemical-properties-of-solution-spin-coated-cu2znsns4-tio2-nanorod-forest-films-with-an-improved-photovoltaic-performance
#10
Zhuoran Wang, Raynald Gauvin, George P Demopoulos
Cu2ZnSnS4 (CZTS), other than in standard p-n junction device architecture, can be employed as a broad light absorber upon coating onto a wide bandgap electron conducting TiO2 film. Earlier CZTS sensitized TiO2 films have yielded low photoconversion efficiency and Voc. In this work, a water-ethanol solution spin coating approach has been applied to directly deposit CZTS nanocrystallites on rutile TiO2 nanorods grown on an FTO substrate (TNR) for evaluation in a sensitized solar cell configuration. The FTO@TNR@CZTS photoanode following controlled annealing is shown to exhibit improved photovoltaic properties...
June 8, 2017: Nanoscale
https://www.readbyqxmd.com/read/28530886/arguing-for-capability-competence-and-capacity-in-htm
#11
Jennifer DeFrancesco
No abstract text is available yet for this article.
May 2017: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/28530879/fear-not-htm-will-thrive-even-as-it-grows
#12
Kenneth E Maddock
No abstract text is available yet for this article.
May 2017: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/28530865/integrated-call-system-bridges-gap-between-htm-and-it
#13
Gavin Stern
No abstract text is available yet for this article.
May 2017: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/28507338/impact-of-trace-minerals-on-wound-healing-of-footpad-dermatitis-in-broilers
#14
Juxing Chen, Guillermo Tellez, Jeffery Escobar, Mercedes Vazquez-Anon
Footpad dermatitis (FPD) is used in the poultry industry as an animal welfare criterion to determine stocking density. Trace minerals (TM) play a role in skin integrity and wound healing. This study evaluated the impact of TM on FPD and consisted of 3 treatments supplemented with 0 (NTM), low (LTM) and high (HTM) TM levels in the same basal diet. On d21, 71% birds in all treatments developed mild FPD and pens were top-dressed with dry litter to promote FPD healing. Compared to NTM, LTM reduced area under the curve (AUC) of FPD lesion scores during d21-42, HTM reduced the AUC of FPD lesion scores during d7-21 and d21-42...
May 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28500139/high-versus-low-gradient-severe-aortic-stenosis-demographics-clinical-outcomes-and-effects-of-the-initial-aortic-valve-replacement-strategy-on-long-term-prognosis
#15
Tomohiko Taniguchi, Takeshi Morimoto, Hiroki Shiomi, Kenji Ando, Norio Kanamori, Koichiro Murata, Takeshi Kitai, Yuichi Kawase, Chisato Izumi, Makoto Miyake, Hirokazu Mitsuoka, Masashi Kato, Yutaka Hirano, Shintaro Matsuda, Tsukasa Inada, Kazuya Nagao, Tomoyuki Murakami, Yasuyo Takeuchi, Keiichiro Yamane, Mamoru Toyofuku, Mitsuru Ishii, Eri Minamino-Muta, Takao Kato, Moriaki Inoko, Tomoyuki Ikeda, Akihiro Komasa, Katsuhisa Ishii, Kozo Hotta, Nobuya Higashitani, Yoshihiro Kato, Yasutaka Inuzuka, Chiyo Maeda, Toshikazu Jinnai, Yuko Morikami, Naritatsu Saito, Kenji Minatoya, Takeshi Kimura
BACKGROUND: There is considerable debate on the management of patients with low-gradient severe aortic stenosis (LG-AS), defined as aortic valve area <1 cm(2) with peak aortic jet velocity ≤4.0 m/s, and mean aortic pressure gradient ≤40 mm Hg. METHODS AND RESULTS: In the CURRENT AS registry (Contemporary Outcomes After Surgery and Medical Treatment in Patients With Severe Aortic Stenosis), there were 2097 patients (initial aortic valve replacement [AVR] strategy: n=977, and conservative strategy: n=1120) with high-gradient severe aortic stenosis (HG-AS) and 1712 patients (initial AVR strategy: n=219, and conservative strategy: n=1493) with LG-AS...
May 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28494163/expression-of-14-3-3-zeta-protein-in-dexamethasone-treated-mice-and-human-tm-1-cells
#16
Qian Liu, Yiming Ye, Xianchai Lin, Yangfan Yang, Kaili Wu, Minbin Yu
PURPOSE: 14-3-3 zeta protein plays a potential protective role in neurodegenerative disease. Given that glaucoma and neurodegenerative diseases share a similar pathogenesis, it is possible that 14-3-3 zeta may have a similar protective effect in the glaucomatous process. In the present study, we measured the expression of 14-3-3 zeta in vivo (mouse eyes) and in vitro in a transformed human trabecular meshwork (HTM) cell line, TM-1, and assessed the possible roles of this protein in dexamethasone (DEX)-treated eyes and HTM cells...
May 11, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28490356/transhepatic-arterial-infusion-chemotherapy-using-a-combination-of-miriplatin-and-cddp-powder-versus-miriplatin-alone-in-the-treatment-of-hepatocellular-carcinoma-a-randomized-controlled-trial
#17
Kenya Kamimura, Takeshi Suda, Takeshi Yokoo, Hiroteru Kamimura, Tsutomu Kanefuji, Atsunori Tsuchiya, Masaaki Takamura, Hirokazu Kawai, Nobuo Waguri, Satoshi Yamagiwa, Shuji Terai
BACKGROUND: Based on promising results from a Phase I study of hepatic arterial infusion chemotherapy using a combination of miriplatin and cisplatin powder (DDP-H) for unresectable hepatocellular carcinoma (UMIN-CTR000003541), a multicenter, open-label, randomized phase II study was conducted to evaluate the efficacy and safety of the combination therapy versus miriplatin monotherapy. METHODS: Nineteen patients, five and fourteen Barcelona-Clinic Liver Cancer staging classification A and B cases, respectively, were randomly assigned to receive either miriplatin monotherapy (n = 9) or miriplatin/DDP-H combination therapy (n = 10)...
May 10, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28481002/non-conjugated-polymer-as-an-efficient-dopant-free-hole-transporting-material-for-perovskite-solar-cells
#18
Yachao Xu, Tongle Bu, Meijin Li, Tianshi Qin, Chengrong Yin, Nanna Wang, Renzhi Li, Jie Zhong, Hai Li, Yong Peng, Jianpu Wang, Linghai Xie, Wei Huang
A new non-conjugated polymer (PVCz-OMeDAD) with good solution processability was developed to serve as an efficient dopant-free hole-transporting material (HTM) for perovskite solar cells (PSCs). PVCz-OMeDAD was simply prepared by the free-radical polymerization of vinyl monomers, which were synthesized from low-cost raw materials through three high-yield synthesis steps. The combination of the flexible non-conjugated polyvinyl main chain and hole-transporting methoxydiphenylamine-substituted carbazole side chains endowed PVCz-OMeDAD with excellent film-forming ability, a suitable energy level, and high hole mobility...
May 8, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28458747/ch3nh3pbi3-grain-growth-and-interfacial-properties-in-meso-structured-perovskite-solar-cells-fabricated-by-two-step-deposition
#19
Zhibo Yao, Wenli Wang, Heping Shen, Ye Zhang, Qiang Luo, Xuewen Yin, Xuezeng Dai, Jianbao Li, Hong Lin
Although the two-step deposition (TSD) method is widely adopted for the high performance perovskite solar cells (PSCs), the CH3NH3PbI3 perovskite crystal growth mechanism during the TSD process and the photo-generated charge recombination dynamics in the mesoporous-TiO2 (mp-TiO2)/CH3NH3PbI3/hole transporting material (HTM) system remains unexploited. Herein, we modified the concentration of PbI2 (C(PbI2)) solution to control the perovskite crystal properties, and observed an abnormal CH3NH3PbI3 grain growth phenomenon atop mesoporous TiO2 film...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28451221/indolo-3-2-b-indole-based-crystalline-hole-transporting-material-for-highly-efficient-perovskite-solar-cells
#20
Illhun Cho, Nam Joong Jeon, Oh Kyu Kwon, Dong Won Kim, Eui Hyuk Jung, Jun Hong Noh, Jangwon Seo, Sang Il Seok, Soo Young Park
We have designed and synthesized fluorinated indolo[3,2-b]indole (IDID) derivatives as crystalline hole-transporting materials (HTM) for perovskite solar cells. The fluorinated IDID backbone enables a tight molecular arrangement stacked by strong π-π interactions, leading to a higher hole mobility than that of the current HTM standard, p,p-spiro-OMeTAD, with a spherical shape and amorphous morphology. Moreover, the photoluminescence quenching in a perovskite/HTM film is more effective at the interface of the perovskite with IDIDF as compared to that of p,p-spiro-OMeTAD...
January 1, 2017: Chemical Science
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