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Zoster immunisation

Luis García-Comas, María Ordobás Gavín, Juan Carlos Sanz Moreno, Belén Ramos Blázquez, M Angeles Gutiérrez Rodríguez, Dolores Barranco Ordóñez
BACKGROUND AND OBJECTIVE: In November 2006, the Community of Madrid included the chickenpox vaccine into the immunisation schedule for children from 15 months of age. This was withdrawn in January 2014. Seroprevalence of antibodies to the virus is estimated after the first 2-3 years from the inclusion of the vaccine, and as well as its evolution since 1999. MATERIAL AND METHOD: A cross-sectional study was conducted on the target population consisting of residents in the Community of Madrid between 2 and 60 years of age...
February 6, 2016: Enfermedades Infecciosas y Microbiología Clínica
Meital Elbaz, Gideon Paret, Avihu Bar Yohai, Ora Halutz, Galia Grisaru-Soen
AIM: The varicella-zoster virus causes infections that are often mild but can cause substantial morbidity and mortality in otherwise healthy children. We examined trends in varicella-related hospitalisations before and after the implementation of a national two-dose varicella vaccination programme in Israel in September 2008. METHODS: This retrospective chart review, performed at three tertiary care paediatric hospitals in greater Tel Aviv, compared data from 2004 to 2008 and 2009 to 2012, before and after the varicella programme was launched...
April 2016: Acta Paediatrica
M P Singh, C Chandran, A Sarwa, A Kumar, M Gupta, A Raj, R K Ratho
PURPOSE: Primary infection with a varicella-zoster virus (VZV) leads to chickenpox. Though the incidence of the disease has decreased in many developed countries due to the introduction of the varicella vaccine, outbreaks continue to occur in developing countries. MATERIALS AND METHODS: The present study reports an outbreak of varicella in an urbanised village in the vicinity of Chandigarh City in North India in November 2013. The outbreak was confirmed by the detection of VZV IgM antibodies in serum samples of clinically suspected patients...
October 2015: Indian Journal of Medical Microbiology
D M MacDougall, B A Halperin, D MacKinnon-Cameron, Li Li, S A McNeil, J M Langley, S A Halperin
OBJECTIVES: Vaccine coverage for recommended vaccines is low among adults. The objective of this study was to assess the knowledge, attitudes, beliefs and behaviours of adults and healthcare providers related to four vaccine-preventable diseases and vaccines (diphtheria-tetanus-pertussis, zoster, pneumococcus and influenza). DESIGN: We undertook a survey and focus groups of Canadian adults and healthcare providers (doctors, nurses, pharmacists). A total of 4023 adults completed the survey and 62 participated in the focus groups; 1167 providers completed the survey and 45 participated in the focus groups...
2015: BMJ Open
Sophie Chien-Hui Wen, Emma Best, Tony Walls, Nigel Dickson, Hamish McCay, Elizabeth Wilson
AIM: Varicella is a vaccine-preventable disease not notifiable in New Zealand (NZ), and varicella vaccine is not funded in the National Immunisation Schedule (NIS). Hospitalisations can occur because of bacterial secondary infection and other complications, which can result in long-term sequelae. Varicella may not be acknowledged in discharge coding when complications occur weeks after infection. Using the New Zealand Paediatric Surveillance Unit (NZPSU), the aim of this study was to document the hospitalisation burden of this disease...
November 2015: Journal of Paediatrics and Child Health
Daniel P Depledge, Eleanor R Gray, Samit Kundu, Samantha Cooray, Anja Poulsen, Peter Aaby, Judith Breuer
UNLABELLED: Varicella-zoster virus (VZV), a double-stranded DNA alphaherpesvirus, is associated with seasonal outbreaks of varicella in nonimmunized populations. Little is known about whether these outbreaks are associated with a single or multiple viral genotypes and whether new mutations rapidly accumulate during transmission. Here, we take advantage of a well-characterized population cohort in Guinea-Bissau and produce a unique set of 23 full-length genome sequences, collected over 7 months from eight households...
December 2014: Journal of Virology
Kristine Macartney, Anita Heywood, Peter McIntyre
BACKGROUND: The prevention of varicella (chickenpox) using live attenuated varicella vaccines has been demonstrated both in randomised controlled trials (RCTs) and in population-based immunisation programmes in countries such as the United States and Australia. Many countries do not routinely immunise children against varicella and exposures continue to occur. Although the disease is often mild, complications such as secondary bacterial infection, pneumonitis and encephalitis occur in about 1% of cases, usually leading to hospitalisation...
2014: Cochrane Database of Systematic Reviews
F Magro, C Abreu
Immunosuppression induced by drugs increase the risk of infections in Crohn's disease (CD) patients. The vaccination rate in CD patients is usually low due to inaccurate information concerning the safety and efficacy of vaccines. Vaccines and immunoglobulins, are artificial ways of protection from common infectious diseases and they have had a major effect on mortality. Herein we detail the need of protection induced by vaccines of measles, varicella, Zoster, papillomavirus, shingles, pneumococcal invasive disease, influenza, hepatitis A and B in CD at diagnosis and during the course of the disease even during immunosuppression periods but with different singularities...
June 2014: Best Practice & Research. Clinical Gastroenterology
Seilesh Kadambari, Ifeanyichukwu Okike, Sonia Ribeiro, Mary E Ramsay, Paul T Heath, Mike Sharland, Shamez N Ladhani
OBJECTIVES: In highly immunised populations viruses contribute to a substantially higher proportion of meningo-encephalitis cases. This national study aimed to describe population trends in laboratory-confirmed, viral meningo-encephalitis reports in England and Wales over a ten-year period. METHODS: Laboratory-confirmed, viral meningo-encephalitis cases submitted by National Health Service hospitals in England and Wales during 2004-13 were analysed. RESULTS: There were 9941 laboratory-confirmed reports of viral meningo-encephalitis in England and Wales over the 10-year period...
October 2014: Journal of Infection
Dinah Gould
The varicella zoster virus causes two infections: varicella, also known as chickenpox occurring mostly in childhood, and herpes zoster, also known as shingles affecting mainly older people. Varicella usually occurs in children under ten years of age. It is generally a mild infection and in the UK vaccination is not offered as part of the routine immunisation programme. However, adults who develop varicella are at risk of developing complications and the infection is likely to be more severe. Serious complications are a particular risk for pregnant women, unborn children, neonates and those who are immunocompromised...
April 16, 2014: Nursing Standard
Anthony L Cunningham, John C B Litt, C Raina Macintyre
No abstract text is available yet for this article.
March 17, 2014: Medical Journal of Australia
Elżbieta Ołdak
Despite the availability of varicella vaccines, few countries have introduced a  universal varicella vaccination to their national immunisation programmes. Major concerns are vaccine efficacy against varicella and herpes zoster as well as duration of post-vaccination protection. This review study presents up-to-date classification of varicella-zoster viral clades, sensitive laboratory tests used for assessment of humoral response against the vaccine-type virus OKA antigens in vaccinees, and benefits of universal varicella vaccination in the USA (since 1995) and in Germany (since 2004)...
October 2013: Medycyna Wieku Rozwojowego
Roman Prymula, Marianne Riise Bergsaker, Susanna Esposito, Leif Gothefors, Sorin Man, Nadezhda Snegova, Mária Stefkovičova, Vytautas Usonis, Jacek Wysocki, Martine Douha, Ventzislav Vassilev, Ouzama Nicholson, Bruce L Innis, Paul Willems
BACKGROUND: Rates of varicella have decreased substantially in countries implementing routine varicella vaccination. Immunisation is possible with monovalent varicella vaccine or a combined measles-mumps-rubella-varicella vaccine (MMRV). We assessed protection against varicella in naive children administered one dose of varicella vaccine or two doses of MMRV. METHODS: This study was done in ten European countries with endemic varicella. Healthy children aged 12-22 months were randomised (3:3:1 ratio, by computer-generated randomisation list, with block size seven) to receive 42 days apart (1) two doses of MMRV (MMRV group), or (2) MMR at dose one and monovalent varicella vaccine at dose two (MMR+V group), or (3) two doses of MMR (MMR group; control)...
April 12, 2014: Lancet
Lucy Pembrey, Pauline Raynor, Paul Griffiths, Shelley Chaytor, John Wright, Andrew J Hall
OBJECTIVE: To estimate the seroprevalence of cytomegalovirus (CMV), Epstein Barr virus (EBV) and varicella zoster virus (VZV) among pregnant women in Bradford by ethnic group and country of birth. METHODS: A stratified random sample of 949 pregnant women enrolled in the Born in Bradford birth cohort was selected to ensure sufficient numbers of White UK born women, Asian UK born women and Asian women born in Asia. Serum samples taken at 24-28 weeks' gestation were tested for CMV IgG, EBV IgG and VZV IgG...
2013: PloS One
Nigel Field, Gayatri Amirthalingam, Pauline Waight, Nick Andrews, Shamez N Ladhani, Albert Jan van Hoek, Peter A C Maple, Kevin E Brown, Elizabeth Miller
INTRODUCTION: In the UK, primary varicella is usually a mild infection in children, but can cause serious illness in susceptible pregnant women and adults. The UK Joint Committee on Vaccination and Immunisation is considering an adolescent varicella vaccination programme. Cost-effectiveness depends upon identifying susceptibles and minimising vaccine wastage, and chickenpox history is one method to screen for eligibility. To inform this approach, we estimated the proportion of adolescents with varicella antibodies by reported chickenpox history...
February 26, 2014: Vaccine
Rosalind Godson
No abstract text is available yet for this article.
June 2013: Community Practitioner: the Journal of the Community Practitioners' & Health Visitors' Association
(no author information available yet)
The results of a clinical trial suggest that zoster vaccination (Zostavax, Sanofi Pasteur MSD) of 1000 healthy persons aged 60 years or over prevents approximately one case of postherpetic neuralgia each year over the next 3 years. Vaccination is less effective in persons over 70 years of age. The results of another clinical trial suggest that vaccination of 1000 healthy persons aged 50 to 59 years prevents about 5 cases of herpes zoster over the following year. The impact on the frequency of postherpetic neuralgia is not known...
December 2012: Prescrire International
Donna B Mak, Max K Bulsara, Megan J Wrate, Dale Carcione, Melissa Chantry, Paul V Efller
AIM: Adolescence is the final opportunity for a large-scale immunisation programme before adulthood. The Western Australian (WA) school-based vaccination programme provides Year 7 students with free vaccination against hepatitis B virus (HBV); diphtheria, tetanus and pertussis (dTpa); varicella zoster virus (VZV); and human papilloma virus (HPV). We aimed to identify factors determining consent form return and vaccination uptake. METHODS: Data were collected via a statewide, web-based database in 2009 and 2010...
November 2013: Journal of Paediatrics and Child Health
Danilo Buonsenso, Benedetta Focarelli, Piero Valentini, Roberta Onesimo
Acute inflammatory polyneuropathy is an inflammatory demyelinating disease triggered by an autoimmune mechanism. It follows an infection or an immunisation after a free interval of 2-30 days. We report a case of a 14-year-old boy who develops an acute rapidly progressive paraplegia, urine incontinence and positive Lasegue a week after a characteristic chickenpox rash. Spinal MRI showed diffuse thickening and leptomeningeal enhancement of cauda equina nerve roots. Intravenous immunoglobulins were given and yielded a dramatic clinical and radiological improvement...
2012: BMJ Case Reports
Inge Nordgaard-Lassen, Jens Frederik Dahlerup, Erika Belard, Jan Gerstoft, Jens Kjeldsen, Knud Kragballe, Pernille Ravn, Inge Juul Sørensen, Klaus Theede, Lone Tjellesen
These national clinical guidelines outlining the screening, prophylaxis and critical information required prior to initiating anti-TNF-alpha treatment have been approved by the Danish Society for Gastroenterology. Anti-TNF-alpha therapy is widely used in gastroenterology (for inflammatory bowel disease), rheumatology (for rheumatoid arthritis, psoriatic arthritis and spondyloarthropathies) and dermatology (for psoriasis). With this background, the Danish Society for Gastroenterology established a group of experts to assess evidence for actions recommended before treatment with anti-TNF-alpha agents...
July 2012: Danish Medical Journal
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