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https://www.readbyqxmd.com/read/29160983/eds-report-strong-surges-in-flu-related-volume-straining-capacity-in-some-regions
#1
David Burmeister, Mohamud Daya, Christopher Sampson
No abstract text is available yet for this article.
April 2017: ED Management: the Monthly Update on Emergency Department Management
https://www.readbyqxmd.com/read/29155672/establishment-of-cdc-global-rapid-response-team-to-ensure-global-health-security
#2
Tasha Stehling-Ariza, Adrienne Lefevre, Dinorah Calles, Kpandja Djawe, Richard Garfield, Michael Gerber, Margherita Ghiselli, Coralie Giese, Ashley L Greiner, Adela Hoffman, Leigh Ann Miller, Lisa Moorhouse, Carlos Navarro-Colorado, James Walsh, Dante Bugli, Cyrus Shahpar
The 2014-2016 Ebola virus disease epidemic in West Africa highlighted challenges faced by the global response to a large public health emergency. Consequently, the US Centers for Disease Control and Prevention established the Global Rapid Response Team (GRRT) to strengthen emergency response capacity to global health threats, thereby ensuring global health security. Dedicated GRRT staff can be rapidly mobilized for extended missions, improving partner coordination and the continuity of response operations. A large, agencywide roster of surge staff enables rapid mobilization of qualified responders with wide-ranging experience and expertise...
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29096130/impaired-self-agency-inferences-in-schizophrenia-the-role-of-cognitive-capacity-and-causal-reasoning-style
#3
M Prikken, A van der Weiden, R S Kahn, H Aarts, N E M van Haren
BACKGROUND: The sense of self-agency, i.e., experiencing oneself as the cause of one's own actions, is impaired in patients with schizophrenia. Normally, inferences of self-agency are enhanced when actual outcomes match with pre-activated outcome information, where this pre-activation can result from explicitly set goals (i.e., goal-based route) or implicitly primed outcome information (i.e., prime-based route). Previous research suggests that patients show specific impairments in the prime-based route, implicating that they do not rely on matches between implicitly available outcome information and actual action-outcomes when inferring self-agency...
September 20, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29076236/choosing-public-or-private-emergency-departments-in-australia
#4
Katherine Walker, Michael Ben-Meir
Emergency medicine was once exclusively provided in public hospitals in Australia, but now over half a million consultations per annum are in private (7% total emergency consultations). Private EDs have excess capacity and are staffed by senior doctors (majority FACEM) with open access to investigations and broad specialist inpatient services. Public EDs struggle with rising attendances and overcapacity. Private hospitals have high levels of patient satisfaction and aim to optimise service provision. A major barrier to private ED attendances is out-of-pocket costs...
October 26, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29069629/choices-of-capture-chromatography-technology-in-antibody-manufacturing-processes
#5
Michael DiLeo, Arthur Ley, Andrew E Nixon, Jie Chen
The capture process employed in monoclonal antibody downstream purification is not only the most critically impacted process by increased antibody titer resulting from optimized mammalian cell culture expression systems, but also the most important purification step in determining overall process throughput, product quality, and economics. Advances in separation technology for capturing antibodies from complex feedstocks have been one focus of downstream purification process innovation for past 10 years. In this study, we evaluated new generation chromatography resins used in the antibody capture process including Protein A, cation exchange, and mixed mode chromatography to address the benefits and unique challenges posed by each chromatography approach...
October 3, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29057896/interactions-between-seagrasses-and-seaweeds-during-surge-nitrogen-acquisition-determine-interspecific-competition
#6
Ana Alexandre, Alexandra Baeta, Aschwin H Engelen, Rui Santos
Seagrasses dominate shallow coastal environments where nitrogen (N) availability in the water column is often sporadic and mainly in the form of pulses. We investigated the N uptake competition between seagrasses and seaweeds through a series of (15)N surge uptake experiments combining single-species and mixed incubations across ammonium concentrations. N surge uptake rates of seagrasses were 2 to 14-fold higher than those of seaweeds in the majority of combinations, showing that seagrasses are generally in a competitive advantage over seaweeds in N-poor environments with N-pulses...
October 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29041994/hospital-surge-capacity-a-web-based-simulation-tool-for-emergency-planners
#7
Matthew F Toerper, Gabor D Kelen, Lauren M Sauer, Jamil D Bayram, Christina Catlett, Scott Levin
The National Center for the Study of Preparedness and Catastrophic Event Response (PACER) has created a publicly available simulation tool called Surge (accessible at http://www.pacerapps.org) to estimate surge capacity for user-defined hospitals. Based on user input, a Monte Carlo simulation algorithm forecasts available hospital bed capacity over a 7-day period and iteratively assesses the ability to accommodate disaster patients. Currently, the tool can simulate bed capacity for acute mass casualty events (such as explosions) only and does not specifically simulate staff and supply inventory...
October 18, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/29034354/prefrontal-connectivity-and-glutamate-transmission-relevance-to-depression-pathophysiology-and-ketamine-treatment
#8
Chadi G Abdallah, Christopher L Averill, Ramiro Salas, Lynnette A Averill, Philip R Baldwin, John H Krystal, Sanjay J Mathew, Daniel H Mathalon
BACKGROUND: Prefrontal global brain connectivity with global signal regression (GBCr) was proposed as a robust biomarker of depression, and was associated with ketamine's mechanism of action. Here, we investigated prefrontal GBCr in treatment-resistant depression (TRD) at baseline and following treatment. Then, we conducted a set of pharmacological challenges in healthy subjects to investigate the glutamate neurotransmission correlates of GBCr. METHODS: In study A, we used functional magnetic resonance imaging (fMRI) to compare GBCr between 22 TRD and 29 healthy control...
October 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28946433/ultrasonic-and-hydrothermal-mediated-synthesis-routes-for-functionalized-mg-al-ldh-comparison-study-on-surface-morphology-basic-site-strength-cyclic-sorption-efficiency-and-effectiveness
#9
Collins I Ezeh, Marco Tomatis, Xiaogang Yang, Jun He, Chenggong Sun
Amine functionalized layered double hydroxide (LDHs) adsorbents prepared using three different routes: co-precipitation, sono-chemical and ultrasonic-assisted high pressure hydrothermal. The prepared adsorbent samples were characterized using X-ray diffraction (XRD), X-ray Photoelectron Spectroscopy (XPS), Scanning electron microscope-Energy dispersive X-ray spectroscopy (SEM-EDX), Temperature Programmed Desorption (TPD), Brunauer-Emmett-Teller (BET), and Thermogravimetric analysis (TGA), respectively. The performance of the prepared adsorbents was tested in a controlled thermal-swing adsorption process to measure its adsorption capacity, regeneration and cyclic efficiencies subsequently...
January 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28906234/an-integrated-needs-based-approach-to-health-service-and-health-workforce-planning-applications-for-pandemic-influenza
#10
Gail Tomblin Murphy, Stephen Birch, Adrian Mackenzie, Janet Rigby, Joanne Langley
Healthcare systems must be responsive to the healthcare needs of the populations they serve. However, typically neither health services nor health workforce planning account for populations' needs for care, resulting in substantial and unnecessary unmet needs. These are further exacerbated during unexpected surges in need, such as pandemics or natural disasters. To illustrate the potential of improved methods to help planning for these types of events, we applied an integrated, needs-based approach to health service and workforce planning in the context of a potential influenza pandemic at the provincial level in Canada...
August 2017: Healthcare Policy, Politiques de Santé
https://www.readbyqxmd.com/read/28887327/uterine-flushings-from-women-treated-with-levonorgestrel-affect-sperm-functionality-in-vitro
#11
Mayel Chirinos, Marta Durand, María Elena González-González, Gabriela Hernández-Silva, Israel Maldonado-Rosas, Pablo Lopez, Fernando Larrea
Levonorgestrel (LNG), a synthetic 19 nor-testosterone derivative, is widely used for emergency contraception. It is well known that LNG prevents ovulation only when given prior to the surge of serum luteinizing hormone (LH) during the periovulatory phase of the menstrual cycle. This observation suggests that LNG, given its contraceptive efficacy, has additional effects other than those affecting ovulation. In this study, we have evaluated the effects on human sperm functionality of uterine flushings (UF) obtained from women at day LH+1 of a control cycle (CTR-LH+1) and after receiving LNG (LNG-LH+1) two days before the surge of LH...
September 8, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28870193/mapping-infectious-disease-hospital-surge-threats-to-lessons-learnt-in-singapore-a-systems-analysis-and-development-of-a-framework-to-inform-how-to-decide-on-planning-and-response-strategies
#12
Shweta R Singh, Richard Coker, Hubertus J-M Vrijhoef, Yee Sin Leo, Angela Chow, Poh Lian Lim, Qinghui Tan, Mark I-Cheng Chen, Zoe Jane-Lara Hildon
BACKGROUND: Hospital usage and service demand during an Infectious Disease (ID) outbreak can tax the health system in different ways. Herein we conceptualize hospital surge elements, and lessons learnt from such events, to help build appropriately matched responses to future ID surge threats. METHODS: We used the Interpretive Descriptive qualitative approach. Interviews (n = 35) were conducted with governance and public health specialists; hospital based staff; and General Practitioners...
September 4, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28865285/towards-an-integrative-model-of-visual-short-term-memory-maintenance-evidence-from-the-effects-of-attentional-control-load-decay-and-their-interactions-in-childhood
#13
Andria Shimi, Gaia Scerif
Over the past decades there has been a surge of research aiming to shed light on the nature of capacity limits to visual short-term memory (VSTM). However, an integrative account of this evidence is currently missing. We argue that investigating parameters constraining VSTM in childhood suggests a novel integrative model of VSTM maintenance, and that this in turn informs mechanisms of VSTM maintenance in adulthood. Over 3 experiments with 7-year-olds and young adults (total N=206), we provide evidence for multiple cognitive processes interacting to constrain VSTM performance...
December 2017: Cognition
https://www.readbyqxmd.com/read/28844459/the-pressing-need-for-point-of-care-diagnostics-for-sickle-cell-disease-a-review-of-current-and-future-technologies
#14
Patrick T McGann, Carolyn Hoppe
Sickle cell disease (SCD) is a common and life threatening inherited blood disorder, affecting over 300,000 newborns per year. Over 75% of SCD births occur in sub-Saharan Africa, where the lack of timely and accurate diagnosis results in premature death within the first few years of life for a majority of affected infants. Current methods to diagnosis SCD require expensive laboratory equipment and reagents, and adequately trained laboratory personnel. In addition, test results are often delayed due to transport and batching of samples in a central laboratory...
August 8, 2017: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/28837886/recovery-and-identification-of-human-remains-in-post-conflict-environments-a-comparative-study-of-the-humanitarian-forensic-programs-in-cyprus-and-kosovo
#15
Maria Mikellide
This study follows the humanitarian forensic programs in Cyprus and Kosovo over a ten-year period with an emphasis on the role of local capacity building. It begins by providing an in-depth historical account of forensic activities, followed by a comparison of the rate of excavations, exhumations and identifications. Through this analysis, a repeated pattern emerges whereby forensic activities in Kosovo start with a surge in values, which drop drastically in the first few years of operations, followed by a steadily declining productivity curve...
October 2017: Forensic Science International
https://www.readbyqxmd.com/read/28789804/all-cause-hospital-admissions-among-older-adults-after-a-natural-disaster
#16
Sue Anne Bell, Mahshid Abir, HwaJung Choi, Colin Cooke, Theodore Iwashyna
STUDY OBJECTIVE: We characterize hospital admissions among older adults for any cause in the 30 days after a significant natural disaster in the United States. The main outcome was all-cause hospital admissions in the 30 days after natural disaster. Separate analyses were conducted to examine all-cause hospital admissions excluding the 72 hours after the disaster, ICU admissions, all-cause inhospital mortality, and admissions by state. METHODS: A self-controlled case series analysis using the 2011 Medicare Provider and Analysis Review was conducted to examine exposure to natural disaster by elderly adults located in zip codes affected by tornadoes during the 2011 southeastern superstorm...
August 5, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28780916/assessing-and-improving-hospital-mass-casualty-preparedness-a-no-notice-exercise
#17
Daniel A Waxman, Edward W Chan, Francesca Pillemer, Timothy Wj Smith, Mahshid Abir, Christopher Nelson
In recent years, mass-casualty incidents (MCIs) have become more frequent and deadly, while emergency department (ED) crowding has grown steadily worse and widespread. The ability of hospitals to implement an effective mass-casualty surge plan, immediately and expertly, has therefore never been more important. Yet, mass-casualty exercises tend to be highly choreographed, pre-scheduled events that provide limited insight into hospitals' true capacity to respond to a no-notice event under real-world conditions...
August 7, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28764818/emergency-response-of-iranian-hospitals-against-disasters-a-practical-framework-for-improvement
#18
Ali Janati, Homayoun Sadeghi-Bazargani, Edris Hasanpoor, Mobin Sokhanvar, Elaheh HaghGoshyie, Abdollah Salehi
OBJECTIVE: Hospital emergency management is a continuous process that requires monolithic integration of planning and response attempts with local and national schemes. The aim of the current study is to evaluate emergency response by hospitals against potential disasters in Tabriz, north-west Iran. METHODS: A cross-sectional study was conducted in the city of Tabriz, in Iran, in 2016. The study population included all hospitals in Tabriz. A total of 18 hospitals were assessed...
August 2, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28735591/-we-expect-seniors-to-be-able-to-prepare-and-recover-from-a-cyclone-as-well-as-younger-members-of-this-community-emergency-management-s-expectations-of-older-adults-residing-in-aging-remote-hamlets-on-australia-s-cyclone-prone-coastline
#19
Sandra Astill, Evonne Miller
OBJECTIVE: To investigate the extent to which older residents feel they can remain "self-reliant" during future natural disasters and to compare the findings with the viewpoints of local policy-makers and with those charged with caring for the elderly both on a day-to-day basis and in times of crisis. METHODS: This study used an array of non-probability snowballing techniques to seek the participation of senior citizens over the age of 65 years, emergency services officers, community health carers, and local government disaster managers located in aging, remote, coastal Australian communities vulnerable to cyclones and storm surges...
July 24, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28721683/mesenchymal-stem-progenitor-cells-derived-from-articular-cartilage-synovial-membrane-and-synovial-fluid-for-cartilage-regeneration-current-status-and-future-perspectives
#20
REVIEW
Yi-Zhou Huang, Hui-Qi Xie, Antonietta Silini, Ornella Parolini, Yi Zhang, Li Deng, Yong-Can Huang
Large articular cartilage defects remain an immense challenge in the field of regenerative medicine because of their poor intrinsic repair capacity. Currently, the available medical interventions can relieve clinical symptoms to some extent, but fail to repair the cartilaginous injuries with authentic hyaline cartilage. There has been a surge of interest in developing cell-based therapies, focused particularly on the use of mesenchymal stem/progenitor cells with or without scaffolds. Mesenchymal stem/progenitor cells are promising graft cells for tissue regeneration, but the most suitable source of cells for cartilage repair remains controversial...
October 2017: Stem Cell Reviews
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