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https://www.readbyqxmd.com/read/27907140/detection-of-acute-radiation-sickness-a-feasibility-study-in-non-human-primates-circulating-mirnas-for-triage-in-radiological-events
#1
Naresh Menon, Claude J Rogers, Agnes I Lukaszewicz, James Axtelle, Marshleen Yadav, Feifei Song, Arnab Chakravarti, Naduparambil K Jacob
Development of biomarkers capable of estimating absorbed dose is critical for effective triage of affected individuals after radiological events. Levels of cell-free circulating miRNAs in plasma were compared for dose-response analysis in non-human primates (NHP) exposed to lethal (6.5 Gy) and sub-lethal (1 and 3 Gy) doses over a 7 day period. The doses and test time points were selected to mimic triage needs in the event of a mass casualty radiological event. Changes in miRNA abundance in irradiated animals were compared to a non-irradiated cohort and a cohort experiencing acute inflammation response from exposure to lipopolysaccharide (LPS)...
2016: PloS One
https://www.readbyqxmd.com/read/27893288/analyzing-injury-severity-of-bus-passengers-with-different-movements
#2
Duo Li, Yifei Zhao, Qiang Bai, Bei Zhou, Hongbiao Ling
OBJECTIVE: Though public transport vehicles are rarely involved in mass casualty accidents, when they are, the number of injuries and fatalities is usually high because of large passenger capacity. Of the few studies that have been conducted on bus safety, the majority focused on vehicle safety features, road environmental factors, as well as driver characteristics. Nevertheless, few studies have attempted to investigate the underlying risk factors related to bus occupants. This paper presents an investigation aimed at identifying the risk factors affecting injury severity of bus passengers with different movements...
November 28, 2016: Traffic Injury Prevention
https://www.readbyqxmd.com/read/27890096/entrance-and-exit-wounds-of-high-velocity-bullet-an-autopsy-analysis-in-the-event-of-dispersing-the-mass-rally-in-bangkok-thailand-may-2010
#3
Vichan Peonim, Smith Srisont, Jitta Udnoon, Sompong Wongwichai, Arisa Thapon, Wisarn Worasuwannarak
Fatal mass casualties by high velocity bullets (HVBs) are rare events in peaceful countries. This study presents 27 forensic autopsy cases with 32 shots fired by 5.56×45mm. HVB (M-16 rifle bullets) during the dispersing the mass rally in Bangkok Thailand, May 2010. It was found that twenty-three (71.88%) typical entrance HVB wounds had round sizes less than the bullet diameters. Most entrance wounds had microtears but no collar abrasion since a HVB has a small streamlined spitzer tip and full metal jacket...
November 2016: Legal Medicine
https://www.readbyqxmd.com/read/27881470/modelling-primary-blast-lung-injury-current-capability-and-future-direction
#4
EDITORIAL
Timothy Scott, E Hulse, M Haque, E Kirkman, J Hardman, P Mahoney
Primary blast lung injury frequently complicates military conflict and terrorist attacks on civilian populations. The fact that it occurs in areas of conflict or unpredictable mass casualty events makes clinical study in human casualties implausible. Research in this field is therefore reliant on the use of some form of biological or non-biological surrogate model. This article briefly reviews the modelling work undertaken in this field until now and describes the rationale behind the generation of an in silico physiological model...
November 23, 2016: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/27855268/hitting-a-moving-target-a-strategic-tool-for-analyzing-terrorist-threats
#5
Ken Coleman, Noriko Ishisoko, Milana Trounce, Kenneth Bernard
The subject of terrorism risk can be confusing for both the general public and for those responsible for protecting us from attack. Relatively minor terrorist threats are often conflated with much more serious ones, in part because it is hard to quantify either intent or technical ability to carry out an attack. Plotting threats on a "potential mass casualties" versus "ease of obtainment or production" matrix creates some order out of a seemingly endless array of worldwide threats, and it highlights those threats that are in need of more urgent attention...
November 17, 2016: Health Security
https://www.readbyqxmd.com/read/27851235/1600-real-time-tracking-of-mass-casualty-incident-markers-in-a-search-and-rescue-training-simulation
#6
Kendall Park, Salman Ahmad, John Gillis, Prasad Calyam, Amy Cheng, Josiah Burchard, Kourtney Meiss, Luke Guerdan
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27833335/the-role-of-dentistry-in-disaster-management-and-victim-identification-an-overview-of-challenges-in-indo-nepal-scenario
#7
REVIEW
Shubha Ranjan Dutta, Purnima Singh, Deepak Passi, Don Varghese, Sarang Sharma
BACKGROUND: Recently, natural disasters and terrorist activities have been leading to mass casualty situations unexpectedly around the globe. In addition to the traditional emergency medical services centering around medically trained and paramedic personnel, dental practitioners having vital skills and attributes may be important in responding to a mass casualty situation. OBJECTIVE: This paper aims at discussing the role of dentists in disaster management and the role of forensic odontology in the disaster victim identification (DVI), its status in India and some suggestions to develop the plans for same...
December 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27825363/pre-hospital-management-of-mass-casualty-civilian-shootings-a-systematic-literature-review
#8
Conor D A Turner, David J Lockey, Marius Rehn
BACKGROUND: Mass casualty civilian shootings present an uncommon but recurring challenge to emergency services around the world and produce unique management demands. On the background of a rising threat of transnational terrorism worldwide, emergency response strategies are of critical importance. This study aims to systematically identify, describe and appraise the quality of indexed and non-indexed literature on the pre-hospital management of modern civilian mass shootings to guide future practice...
November 8, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27824239/emergency-clinical-networks-represent-a-real-opportunity-for-dealing-with-mass-casualty-events
#9
Adriano Peris
No abstract text is available yet for this article.
November 8, 2016: Minerva Anestesiologica
https://www.readbyqxmd.com/read/27790383/mass-casualty-decontamination-guidance-and-psychosocial-aspects-of-cbrn-incident-management-a-review-and-synthesis
#10
Holly Carter, Richard Amlôt
INTRODUCTION: Mass casualty decontamination is an intervention employed by first responders at the scene of an incident involving noxious contaminants.  Many countries have sought to address the challenge of decontaminating large numbers of affected casualties through the provision of rapidly deployable temporary showering structures, with accompanying decontamination protocols.  In this paper we review decontamination guidance for emergency responders and associated research evidence, in order to establish to what extent psychosocial aspects of casualty management have been considered within these documents...
September 27, 2016: PLoS Currents
https://www.readbyqxmd.com/read/27790381/mass-casualty-decontamination-in-a-chemical-or-radiological-nuclear-incident-further-guiding-principles
#11
Holly Carter, Richard Amlôt, Richard Williams, G James Rubin, John Drury
This short report presents a response to an article written by Cibulsky et al. (2016). The paper by Cibulsky et al. presents a useful and timely overview of the evidence surrounding the technical and operational aspects of mass casualty decontamination. It identifies three priority targets for future research, the third of which is how casualties' needs can be met in ways that best support compliance with and effectiveness of casualty decontamination. While further investigation into behavioural, communication and privacy issues during mass decontamination is warranted, there is now a substantial body of research in this area which is not considered in detail in the succinct summary provided by Cibulsky et al...
September 15, 2016: PLoS Currents
https://www.readbyqxmd.com/read/27788698/a-pilot-study-examining-the-speed-and-accuracy-of-triage-for-simulated-disaster-patients-in-an-emergency-department-setting-comparison-of-a-computerized-version-of-canadian-triage-acuity-scale-ctas-and-simple-triage-and-rapid-treatment-start-methods
#12
Gwynn Curran-Sills, Jeffrey M Franc
OBJECTIVE: To compare emergency department triage nurses' time to triage and accuracy of a simulated mass casualty incident (MCI) population using a computerized version of CTAS or START systems. METHODS: This pilot study was a prospective trial using a convenience sample. A total of 20 ED triage nurses, 10 in each arm of the study, were recruited. The paper-based questionnaire contained nine simulated MCI vignettes. An expert panel arrived at consensuses on the wording of the vignettes and created a standard triage score from which to compare the study participants...
October 28, 2016: CJEM
https://www.readbyqxmd.com/read/27757716/simedis-a-discrete-event-simulation-model-for-testing-responses-to-mass-casualty-incidents
#13
Michel Debacker, Filip Van Utterbeeck, Christophe Ullrich, Erwin Dhondt, Ives Hubloue
It is recognized that the study of the disaster medical response (DMR) is a relatively new field. To date, there is no evidence-based literature that clearly defines the best medical response principles, concepts, structures and processes in a disaster setting. Much of what is known about the DMR results from descriptive studies and expert opinion. No experimental studies regarding the effects of DMR interventions on the health outcomes of disaster survivors have been carried out. Traditional analytic methods cannot fully capture the flow of disaster victims through a complex disaster medical response system (DMRS)...
December 2016: Journal of Medical Systems
https://www.readbyqxmd.com/read/27752635/a-study-on-the-disaster-medical-response-during-the-mauna-ocean-resort-gymnasium-collapse
#14
Myeong-Il Cha, Gi Woon Kim, Chu Hyun Kim, Minhong Choa, Dai Hai Choi, Inbyung Kim, Soon Joo Wang, In Sool Yoo, Han Deok Yoon, Kang Hyun Lee, Suck Ju Cho, Tag Heo, Eun Seog Hong
OBJECTIVE: To investigate and document the disaster medical response during the Gyeongju Mauna Ocean Resort gymnasium collapse on February 17, 2014. METHODS: Official records of each institution were verified to select the study population. All the medical records and emergency medical service run sheets were reviewed by an emergency physician. Personal or telephonic interviews were conducted, without a separate questionnaire, if the institutions or agencies crucial to disaster response did not have official records or if information from different institutions was inconsistent...
September 2016: Clin Exp Emerg Med
https://www.readbyqxmd.com/read/27745954/intranasal-delivery-of-a-protein-subunit-vaccine-using-a-tobacco-mosaic-virus-platform-protects-against-pneumonic-plague
#15
Paul M Arnaboldi, Mariya Sambir, Christina D'Arco, Lauren A Peters, Jos F M L Seegers, Lloyd Mayer, Alison A McCormick, Raymond J Dattwyler
Yersinia pestis, one of history's deadliest pathogens, has killed millions over the course of human history. It has attributes that make it an ideal choice to produce mass casualties and is a prime candidate for use as a biological weapon. When aerosolized, Y. pestis causes pneumonic plague, a pneumonia that is 100% lethal if not promptly treated with effective antibiotics. Currently, there is no FDA approved plague vaccine. The current lead vaccine candidate, a parenterally administered protein subunit vaccine comprised of the Y...
November 11, 2016: Vaccine
https://www.readbyqxmd.com/read/27734440/medical-provider-ballistic-protection-at-active-shooter-events
#16
Jason P Stopyra, William P Bozeman, David W Callaway, James Winslow, Henderson D McGinnis, Justin Sempsrott, Lisa Evans-Taylor, Roy L Alson
There is some controversy about whether ballistic protective equipment (body armor) is required for medical responders who may be called to respond to active shooter mass casualty incidents. In this article, we describe the ongoing evolution of recommendations to optimize medical care to injured victims at such an incident. We propose that body armor is not mandatory for medical responders participating in a rapid-response capacity, in keeping with the Hartford Consensus and Arlington Rescue Task Force models...
2016: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/27718129/the-readiness-of-emergency-and-trauma-care-in-low-and-middle-income-countries-a-cross-sectional-descriptive-study-of-42-public-hospitals-in-albania
#17
Rifat Latifi, Jayleen K L Gunn, John A Stroster, Edmond Zaimi, Fatos Olldashi, Agron Dogjani, Mihal Kerci, Xheladin Draçini, Julian Kuçani, Zhaneta Shatri, Agim Kociraj, Arian Boci, Ross I Donaldson
BACKGROUND: Traumatic injuries have become a substantial but neglected epidemic in low- and middle-income countries (LMICs), but emergency rooms (ERs) in these countries are often staffed with healthcare providers who have minimal emergency training and experience. The aim of this paper was to describe the specialized training, available interventions, and the patient management strategies in the ERs in Albanian public hospitals. METHODS: A cross-sectional descriptive study of 42 ERs in the Republic of Albania between September 5, 2014, and December 29, 2014 was performed...
December 2016: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27710702/state-of-the-art-advances-in-radiation-biodosimetry-for-mass-casualty-events-involving-radiation-exposure
#18
Mary Sproull, Kevin Camphausen
With the possibility of large-scale terrorist attacks around the world, the need for modeling and development of new medical countermeasures for potential future chemical, biological, radiological and nuclear (CBRN) has been well established. Project Bioshield, initiated in 2004, provided a framework to develop and expedite research in the field of CBRN exposures. To respond to large-scale population exposures from a nuclear event or radiation dispersal device (RDD), new methods for determining received dose using biological modeling became necessary...
November 2016: Radiation Research
https://www.readbyqxmd.com/read/27686284/the-harmonization-process-to-set-up-and-maintain-an-operational-biological-and-physical-retrospective-dosimetry-network-qa-qm-applied-to-the-reneb-network
#19
Eric Gregoire, Liz Ainsbury, Leonardo Barrios, Céline Bassinet, Paola Fattibene, Ulrike Kulka, Ursula Oestreicher, Gabriel Pantelias, Georgia Terzoudi, Francois Trompier, Philippe Voisin, Anne Vral, Andrzej Wojcik, Laurence Roy
PURPOSE: The European Network of Biological and Physical Retrospective Dosimetry 'RENEB' has contributed to European radiation emergency preparedness. To give homogeneous dose estimation results, RENEB partners must harmonize their processes. MATERIALS AND METHODS: A first inter-comparison focused on biological and physical dosimetry was used to detect the outliers in terms of dose estimation. Subsequently, trainings were organized to improve both tools dose estimation...
August 11, 2016: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/27651979/qualitative-analysis-of-surveyed-emergency-responders-and-the-identified-factors-that-affect-first-stage-of-primary-triage-decision-making-of-mass-casualty-incidents
#20
Kelly R Klein, Frederick M Burkle, Raymond Swienton, Richard V King, Thomas Lehman, Carol S North
INTRODUCTION: After all large-scale disasters multiple papers are published describing the shortcomings of the triage methods utilized. This paper uses medical provider input to help describe attributes and patient characteristics that impact triage decisions. METHODS: A survey distributed electronically to medical providers with and without disaster experience. Questions asked included what disaster experiences they had, and to rank six attributes in order of importance regarding triage...
2016: PLoS Currents
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