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https://www.readbyqxmd.com/read/28066812/the-denture-associated-oral-microbiome-in-health-and-stomatitis
#1
Baochen Shi, Tingxi Wu, Jeffrey McLean, Anna Edlund, Youngik Young, Xuesong He, Hongyang Lv, Xuedong Zhou, Wenyuan Shi, Huiying Li, Renate Lux
While investigation of the microbiome on natural oral surfaces has generated a wealth of information, few studies have examined the microbial communities colonizing dentures and their relationship to oral health. To address this knowledge gap, we characterized the bacterial community associated with dentures and remaining teeth in healthy individuals and patients with denture stomatitis. The microbiome compositions of matched denture and tooth plaque samples of 10 healthy individuals and 9 stomatitis patients were determined by 16S rRNA gene pyrosequencing...
November 2016: MSphere
https://www.readbyqxmd.com/read/28063305/inhibitory-effects-of-lactobacillus-rhamnosus-and-lactobacillus-casei-on-candida-biofilm-of-denture-surface
#2
Young-Gyun Song, Sung-Hoon Lee
OBJECTIVE: Candida albicans biofilm is associated with denture-related stomatitis and oral candidiasis of elderly. Probiotics are beneficial bacteria and have antibacterial activity against pathogenic bacteria. The purpose of this study was to investigate the antifungal activity of various probiotics against C. albicans and the inhibitory effects of probiotics on Candida biofilm on the denture surface. DESIGN: The spent culture media of various probiotics were investigated the antifungal efficacy against C...
December 31, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/28032543/candida-albicans-biofilm-heterogeneity-does-not-influence-denture-stomatitis-but-strongly-influences-denture-cleansing-capacity
#3
Lindsay E O'Donnell, Hasanain K A Alalwan, Ryan Kean, Gareth Calvert, Christopher J Nile, David F Lappin, Douglas Roberston, Craig Williams, Gordon Ramage, Leighann Sherry
Approximately 20% of the UK population wear some form of denture prosthesis, resulting in denture stomatitis in half of these individuals. Candida albicans is primarily attributed as the causative agent, due to its biofilm forming ability. Recently, there has been increasing evidence of C. albicans biofilm heterogeneity and the negative impact it can have clinically; however, this phenomenon has yet to be studied in relation to denture isolates. The aims of this study were to evaluate C. albicans biofilm formation of clinical denture isolates in a denture environment, and assess antimicrobial activity of common denture cleansers against these tenacious communities...
December 29, 2016: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28018842/c-dubliniensis-in-an-immunocompetent-patient-with-metal-lingual-frenulum-piercing
#4
Gary Ventolini, Peihsuan Tsai, Lee David Moore
Candida spp. are opportunistic unicellular fungi, known to cause oral, vaginal, lung and occasionally systemic infections. Characteristically, they colonize the oral cavity, the mucosal surfaces of the cheek, palate, and tongue. Usually harmless, oral Candidas may become pathogenic under immunosuppressive conditions, dentures presence, or salivary flow impairment. Accurate species identification is important because C. dubliniensis can rapidly develop fluconazole resistance. We report C. dubliniensis in an immunocompetent patient with a metal lingual frenulum piercing...
December 2016: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28011958/cationic-porphyrin-mediated-photodynamic-inactivation-of-candida-biofilms-and-the-effect-of-miconazole
#5
A Davies, S Gebremedhin, M Yee, R J Padilla, N Duzgunes, K Konopka, B Dorocka-Bobkowska
The formation of biofilms by Candida and the increasing resistance of Candida species to antifungals contribute to the high recurrence rates of denture stomatitis. This increase has stimulated an interest in antimicrobial photodynamic therapy (aPDT) as an alternative treatment. We examined the photoactivity of the porphyrin-based photosensitizer, TMP-1363, against biofilms of C. albicans, C. glabrata, C. tropicalis and C. parapsilosis, and the effect of the combined use of miconazole and aPDT. Biofilms of three American Type Culture Collection (ATCC) strains and four clinical isolates developed on poly(methyl methacrylate) (PMMA) disks, were incubated with miconazole, followed by treatment with TMP-1363 for 30 min at 37°C...
October 2016: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/27999492/evaluation-of-denture-related-factors-predisposing-to-denture-stomatitis-in-a-lebanese-population
#6
Georges Aoun, Antoine Cassia
BACKGROUND: Denture stomatitis is a common fungal oral infection of multifactorial etiology. Denture-related factors such as denture's age, hygiene, night wearing and colonization by Candida albicans are known to predispose to denture stomatitis. The aim of this study was to evaluate these factors and their relationship with the occurrence of denture stomatitis in a Lebanese population. MATERIAL AND METHODS: Sixty patients (40 women, 20 men; age range 40-80 years) showing clinical evidence of denture-related stomatitis were selected for this study...
October 2016: Materia Socio-medica
https://www.readbyqxmd.com/read/27974977/total-cad-cam-supported-method-for-manufacturing-removable-complete-dentures
#7
Arthur Furtado de Mendonça, Mario Furtado de Mendonça, George Shelby White, Georges Sara, Darren Littlefair
The incorporation of computer-aided design/computer-aided manufacturing (CAD/CAM) technology into complete denture fabrication brings about several advantages to the fabrication process, providing better predictability of the desired outcomes and high accuracy of denture fit, mainly because the milling of prepolymerized acrylic resin eliminates the shrinkage of the acrylic base. Also, there is a decrease in the porosity when compared to a conventionally processed denture, and consequently there is a decrease in the retention of Candida albicans on the denture base...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27942552/susceptibility-of-candida-albicans-and-candida-dubliniensis-to-photodynamic-therapy-using-four-dyes-as-the-photosensitizer
#8
Nasim Hosseini, Samira Yazdanpanah, Maryam Saki, Fahimeh Rezazadeh, Janan Ghapanchi, Kamiar Zomorodian
STATEMENT OF THE PROBLEM: Oral candidiasis is the most common opportunistic infection affecting the human oral cavity. Photodynamic therapy, as one of its proposed treatment modalities, needs a distinct dye for achieving the best effect. PURPOSE: The purpose of this study was to evaluate photosensitization effects of four distinct dyes on standard suspension of Candida albicans (C. albicans) and Candida dubliniensis (C. dubliniensis) and biofilm of C. albicans considering the obtained optimum dye concentration and duration of laser irradiation...
December 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27927282/effect-of-sodium-hypochlorite-and-ricinus-communis-solutions-on-control-of-denture-biofilm-a-randomized-crossover-clinical%C3%A2-trial
#9
Carolina Noronha Ferraz de Arruda, Marcela Moreira Salles, Maurício Malheiros Badaró, Viviane de Cássia Oliveira, Ana Paula Macedo, Cláudia Helena Silva-Lovato, Helena de Freitas Oliveira Paranhos
STATEMENT OF PROBLEM: The prevalence of complete edentulism remains high in the elderly, and previous data have shown that poor denture hygiene is common among edentulous patients. PURPOSE: The purpose of this randomized crossover trial was to evaluate the efficacy of denture cleansers in terms of biofilm removal, antimicrobial action, and the remission of denture stomatitis. MATERIAL AND METHODS: Fifty denture wearers with denture stomatitis were instructed to brush their dentures (brush and soap) and to soak them (20 minutes/14 days) in 4 solutions, as follows: C (control), 0...
December 4, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27927053/future-therapies-targeted-towards-eliminating-candida-biofilms-and-associated-infections
#10
H M H N Bandara, V H Matsubara, L P Samaranayake
Candida species are common human commensals and cause either superficial or invasive opportunistic infections. The biofilm form of candida as opposed to its suspended, planktonic form, is predominantly associated with these infections. Alternative or adjunctive therapies are urgently needed to manage Candida infections as the currently available short arsenal of antifungal drugs has been compromised due to their systemic toxicity, cross-reactivity with other drugs, and above all, by the emergence of drug-resistant Candida species due to irrational drug use...
December 16, 2016: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/27920509/correlation-between-age-and-gender-in-candida-species-infections-of-complete-denture-wearers-a-retrospective-analysis
#11
Jolanta E Loster, Aneta Wieczorek, Bartłomiej W Loster
AIM: Denture-related stomatitis is a disorder that often affects denture wearers. The purpose of this study was to evaluate the intensity, genera, and frequency of yeasts in the oral cavity of complete denture wearers in terms of subject gender and age. MATERIALS AND METHODS: Nine hundred twenty patients (307 males and 613 females) with complete upper dentures were selected for the study and divided into four age groups: ≤50 years, 51-60, 61-70, and >70 years...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27915298/multilocus-sequence-typing-mlst-analysis-of-candida-albicans-isolates-colonizing-acrylic-dentures-before-and-after-denture-replacement
#12
Khai How Choo, Hee Ji Lee, Nicholas J Knight, Ann R Holmes, Richard D Cannon
Yeast, in particular Candida albicans, are the principal fungal cause of denture stomatitis, and can also be present as a commensal in many individuals. Few studies, however, have examined oral retention of yeast strains over time. We analyzed the yeast present in saliva samples and from the dentures of 10 individuals colonized with yeast but with no signs of stomatitis, before new complete maxillary dentures were fitted and also at 1, 3, and 6 months after denture replacement. Yeast species were presumptively identified on selective agar plates and were present in nine individuals before denture replacement and in six at the 6-month time point...
December 2, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27891466/an-in-vitro-evaluation-of-retention-colonization-and-penetration-of-commonly-used-denture-lining-materials-by-candida-albicans
#13
Sushma Krishnamurthy, Rajendra B Hallikerimath
INTRODUCTION: Colonization of the surface by Candida albicans and related Candida species is one of the major concerns of denture lining materials. AIM: We evaluated retention, colonization and penetration of the four denture lining materials namely Molloplast B, Permaflex, GC Soft Liner and Ufi Gel Hard C by Candida albicans. MATERIAL AND METHODS: a) Evaluation of retention: Five test discs of each material with smooth surface on one side and rough on the other were prepared and surface roughness (Ra) was measured with profilometer...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27870138/promise-of-combining-antifungal-agents-in-denture-adhesives-to-fight-candida-species-infections
#14
Jorge L Garaicoa, Carol L Fischer, Amber M Bates, Julie Holloway, Gustavo Avila-Ortiz, Janet M Guthmiller, Georgia K Johnson, Clark Stanford, Kim A Brogden
PURPOSE: Several complications may arise in patients wearing complete prosthetic appliances, including denture-associated infections and mucosal stomatitis due to Candida species. This study evaluated the activity of anti-Candida agents in denture adhesive and the cytotoxicities of these preparations for primary human gingival epithelial (GE) keratinocytes. MATERIALS AND METHODS: The anti-Candida activities of antimicrobial peptides, antimicrobial lipids, and antifungal agents against C...
November 21, 2016: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/27825678/microbiological-and-clinical-assessment-of-the-abutment-and-non-abutment-teeth-of-partial-removable-denture-wearers
#15
Luciana Costa, Cássio do Nascimento, Valéria Oliveira Pagnano de Souza, Vinícius Pedrazzi
OBJECTIVE: The aim of this study was assessing the changes in both clinical and microbiological parameters of healthy individuals after rehabilitation with removable partial denture (RPD). DESIGN: 11 women received unilateral or bilateral free-end saddle RPD in the mandibular arch. Clinical and microbiological parameters of abutment, non-abutment, and antagonist teeth were assessed at baseline (RPD installation) and after 7, 30, 90, and 180days of function. The Checkerboard DNA-DNA hybridization technique was used to identify and quantify up to 43 different microbial species from subgingival biofilm samples...
November 3, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/27812615/porosity-of-temporary-denture-soft-liners-containing-antifungal-agents
#16
Jozely Francisca Mello Lima, Janaína Gomes Maciel, Juliana Hotta, Ana Carolina Pero Vizoto, Heitor Marques Honório, Vanessa Migliorini Urban, Karin Hermana Neppelenbroek
Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner (Trusoft) modified by minimum inhibitory concentrations (MICs) of antifungal agents for Candida albicans biofilm. Material and Methods: The porosity was measured by water absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65×10×3.3 mm) of both materials was 50% anhydrous calcium chloride (S50)...
September 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/27745775/new-denture-adhesive-containing-miconazole-nitrate-polymeric-microparticles-antifungal-adhesive-force-and-toxicity-properties
#17
Andrés Felipe Cartagena, Luís Antonio Esmerino, Rogerio Polak-Junior, Sibelli Olivieri Parreiras, Milton Domingos Michél, Paulo Vitor Farago, Nara Hellen Campanha
OBJECTIVE: The purpose of this study was to develop a new oral drug delivery system by incorporating polymeric miconazole nitrate (MN) microparticles on an experimental antifungal denture adhesive (DA). METHODS: Spray drying Eudragit L-100 (E) and Gantrez MS-955 (G) MN-microparticles were incorporated in DA. DAE1, DAG1, DAEG1, DAE2, DAG2, DAEG2 groups were obtained from the combination of polymers used in MN-microparticles (E, G and EG) and concentration of MN into DA (1, for 1% and 2, for 2%)...
October 10, 2016: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/27739378/intraoral-device-for-optimal-antifungal-delivery-in-a-rat-model
#18
Juliana Hotta, Wilson Gustavo Cral, Vinicius Tatsuyuji Sakima, Vanessa Soares Lara, Vanessa Migliorini Urban, Karin Hermana Neppelenbroek
BACKGROUND: Antifungal agents incorporated into temporary denture resilient liners as drug carries and delivery have been suggested as an alternative treatment for denture stomatitis. However, to test the in vivo biocompatibility of this protocol, standardization of an intraoral device for optimal drug delivery is required. OBJECTIVE: Standardized criteria were produced to adjust an acrylic intraoral device (IOD) for rats feasible for denture stomatitis treatment by sustained drug-delivery based on minimal inhibitory drug concentrations (MICs) of antifungals for Candida albicans biofilm...
October 13, 2016: Current Drug Delivery
https://www.readbyqxmd.com/read/27725519/efficacy-of-denture-cleaners-on-the-surface-roughness-and-candida-albicans-adherence-of-sealant-agent-coupled-denture-base-materials
#19
Ayşegül Köroğlu, Onur Şahin, Doğu Ömür Dede, Şule Tuğba Deniz, Nurdan Karacan Sever, Serkan Özkan
This study investigated the effect of denture cleansers on the surface roughness and Candida albicans adherence of surface sealant agent coupled denture base resins. One hundred and twenty specimens were fabricated from 2 polymethyl methacrylate (PMMA) (Meliodent; Acron MC) and 1 polyamide (Deflex) denture base materials, coated with a sealant agent (Palaseal) and divided into 4 groups (n=10) according to overnight cleaning procedures: distilled water (control), 5% sodium hypochlorite (NaOCl) and two different sodium perborate (Corega; Rapident)...
2016: Dental Materials Journal
https://www.readbyqxmd.com/read/27711988/status-of-removable-dentures-and-relationship-with-oral-candida-associated-factors-in-a-geriatric-population-in-catalonia
#20
Elisenda Martori, Raúl Ayuso-Montero, Eva Willaert, Miguel Viñas, Maria Peraire, Jordi Martinez-Gomis
PURPOSE: Colonization by Candida is related to wearing a denture. How denture type, status, and maintenance play a role in determining Candida colonization remains unknown. This work evaluated removable denture status in an elderly population and explored the association between denture-related factors and oral Candida colonization as determined by systemic and local factors. MATERIALS AND METHODS: Socio-demographic, general health, and behavioral data and oral factors were registered by means of a questionnaire...
October 6, 2016: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
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