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Candida denture

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https://www.readbyqxmd.com/read/28223859/histatin-peptides-pharmacological-functions-and-their-applications-in-dentistry
#1
REVIEW
Zohaib Khurshid, Shariq Najeeb, Maria Mali, Syed Faraz Moin, Syed Qasim Raza, Sana Zohaib, Farshid Sefat, Muhammad Sohail Zafar
There are many human oral antimicrobial peptides responsible for playing important roles including maintenance, repairing of oral tissues (hard or soft) and defense against oral microbes. In this review we have highlighted the biochemistry, physiology and proteomics of human oral histatin peptides, secreted from parotid and submandibular salivary glands in human. The significance of these peptides includes capability for ionic binding that can kill fungal Candida albicans. They have histidine rich amino acid sequences (7-12 family members; corresponding to residues 12-24, 13-24, 12-25, 13-25, 5-11, and 5-12, respectively) for Histatin-3...
January 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28223199/poly-methyl-methacrylate-with-tio2-nanoparticles-inclusion-for-stereolitographic-complete-denture-manufacturing-the-fututre-in-dental-care-for-elderly-edentulous-patients
#2
Eugenia Eftimie Totu, Aurelia Cristina Nechifor, Gheorghe Nechifor, Hassan Y Aboul-Enein, Corina Marilena Cristache
OBJECTIVES: The aim of this study was to obtain a Poly(methylmethacrylate) (PMMA)-TiO2 nanocomposite material with improved antibacterial characteristics, suitable for manufacturing 3D printed dental prosthesis. METHODS: 0.2, 0.4, 0.6, 1, 2.5 by weight% of TiO2 nanoparticles have been added to the commercially available stereolithographic PMMA material and the obtained nanocomposites have been analyzed using FTIR, SEM and also tested for antimicrobial efficacy against bacterial cultures from Candida species (C...
February 18, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28222870/influence-of-3-different-forms-of-a-commercially-available-denture-adhesive-material-on-the-growth-of-candida-species-an-in%C3%A2-vitro-study
#3
Anuram Rajaram, Smita Sara Manoj
STATEMENT OF PROBLEM: Although different forms of denture adhesives are widely used by the elderly, insufficient information is available for the effect of adhesives on the growth of Candida species. PURPOSE: The purpose of this in vitro study was to compare the influence of 3 different forms of a commercially available denture adhesive material on the growth of Candida species by monitoring the pH and number of colonies in the growth medium at different incubation periods...
February 17, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28178179/diminished-antimicrobial-peptide-and-antifungal-antibiotic-activities-against-candida-albicans-in-denture-adhesive
#4
Amber M Bates, Jorge L Garaicoa, Carol L Fischer, Kim A Brogden
The underlying causes of denture stomatitis may be related to the long-term use of adhesives, which may predispose individuals to oral candidiasis. In this study, we hypothesize that antimicrobial peptides and antifungal antibiotics have diminished anti-Candida activities in denture adhesive. To show this, nine antimicrobial peptides and five antifungal antibiotics with and without 1.0% denture adhesive were incubated with Candida albicans strains ATCC 64124 and HMV4C in radial diffusion assays. In gels with 1...
February 6, 2017: Antibiotics
https://www.readbyqxmd.com/read/28148273/prevalence-of-candida-albicans-and-non-albicans-on-the-tongue-dorsa-of-elderly-people-living-in-a-post-disaster-area-a-cross-sectional-survey
#5
Toshiro Sato, Mitsuo Kishi, Miki Suda, Kiyomi Sakata, Haruki Shimoda, Hiroyuki Miura, Akira Ogawa, Seiichiro Kobayashi
BACKGROUND: Candida species are normal commensal organisms of the mouth. However, they can cause oral mucosal and severe systemic infections in persons with reduced immune function, which is common in the very elderly. In post-disaster areas, the number of elderly residents rapidly increases due to the outflow of younger generations. Hence, we examined the prevalence of Candida albicans and non-albicans in association with oral and systemic conditions, life style, medications, and living conditions...
February 1, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28138698/dose%C3%A2-dependent-effect-of-lysozyme-upon-candida%C3%A2-albicans-biofilm
#6
Sarra Sebaa, Nicolas Hizette, Zahia Boucherit-Otmani, Philippe Courtois
The present study investigated the in vitro effect of lysozyme (0-1,000 µg/ml) on Candida albicans (C. albicans) biofilm development. Investigations were conducted on C. albicans ATCC 10231 and on 10 clinical isolates from dentures. Strains were cultured aerobically at 37˚C in Sabouraud broth. Yeast growth was evaluated by turbidimetry. Biofilm biomass was quantified on a polystyrene support by crystal violet staining and on acrylic surfaces by counts of colony forming units. Lysozyme affected biofilm formation to a greater extent than it affected growth...
January 25, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28115357/synthesis-antifungal-activity-and-biocompatibility-of-novel-dabco-compounds-and-dabco-containing-denture-base-resins
#7
Jenny L Herman, Yapin Wang, Elizabeth Lilly, Thomas Lallier, Suleiman Hamdan, Xiaoming Xu, Paul L Fidel, Mairi C Noverr
The fungal pathogen Candida albicans causes a variety of oral infections including denture stomatitis, which is characterized by inflammation of the oral mucosa in direct contact with dentures, and affects a significant number of otherwise healthy denture wearers. While antifungal treatment reduces symptoms, infections are often recurrent. One strategy to address this problem is to incorporate compounds with fungicidal activities into denture materials to prevent colonization. Our laboratory synthesized novel derivatives of DABCO (1,4-diazabicyclo[2...
January 23, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28091850/repeated-applications-of-photodynamic-therapy-on-candida-glabrata-biofilms-formed-in-acrylic-resin-polymerized
#8
Lírian Silva de Figueiredo Freitas, Rodnei Dennis Rossoni, Antonio Olavo Cardoso Jorge, Juliana Campos Junqueira
Previous studies have been suggested that photodynamic therapy (PDT) can be used as an adjuvant treatment for denture stomatitis. In this study, we evaluated the effects of multiple sessions of PDT on Candida glabrata biofilms in specimens of polymerized acrylic resin formed after 5 days. Subsequently, four applications of PDT were performed on biofilms in 24-h intervals (days 6-9). Also, we evaluated two types of PDT, including application of laser and methylene blue or light-emitting diode (LED) and erythrosine...
January 14, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28066812/the-denture-associated-oral-microbiome-in-health-and-stomatitis
#9
Baochen Shi, Tingxi Wu, Jeffrey McLean, Anna Edlund, Youngik Young, Xuesong He, Hongyang Lv, Xuedong Zhou, Wenyuan Shi, Huiying Li, Renate Lux
While investigation of the microbiome on natural oral surfaces has generated a wealth of information, few studies have examined the microbial communities colonizing dentures and their relationship to oral health. To address this knowledge gap, we characterized the bacterial community associated with dentures and remaining teeth in healthy individuals and patients with denture stomatitis. The microbiome compositions of matched denture and tooth plaque samples of 10 healthy individuals and 9 stomatitis patients were determined by 16S rRNA gene pyrosequencing...
November 2016: MSphere
https://www.readbyqxmd.com/read/28063305/inhibitory-effects-of-lactobacillus-rhamnosus-and-lactobacillus-casei-on-candida-biofilm-of-denture-surface
#10
Young-Gyun Song, Sung-Hoon Lee
OBJECTIVE: Candida albicans biofilm is associated with denture-related stomatitis and oral candidiasis of elderly. Probiotics are beneficial bacteria and have antibacterial activity against pathogenic bacteria. The purpose of this study was to investigate the antifungal activity of various probiotics against C. albicans and the inhibitory effects of probiotics on Candida biofilm on the denture surface. DESIGN: The spent culture media of various probiotics were investigated the antifungal efficacy against C...
December 31, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/28032543/candida-albicans-biofilm-heterogeneity-does-not-influence-denture-stomatitis-but-strongly-influences-denture-cleansing-capacity
#11
Lindsay E O'Donnell, Hasanain K A Alalwan, Ryan Kean, Gareth Calvert, Christopher J Nile, David F Lappin, Douglas Robertson, Craig Williams, Gordon Ramage, Leighann Sherry
Approximately 20  % of the UK population wear some form of denture prosthesis, resulting in denture stomatitis in half of these individuals. Candida albicans is primarily attributed as the causative agent, due to its biofilm -forming ability. Recently, there has been increasing evidence of C. albicans biofilm heterogeneity and the negative impact it can have clinically; however, this phenomenon has yet to be studied in relation to denture isolates. The aims of this study were to evaluate C. albicans biofilm formation of clinical denture isolates in a denture environment and to assess antimicrobial activity of common denture cleansers against these tenacious communities...
January 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28018842/c-dubliniensis-in-an-immunocompetent-patient-with-metal-lingual-frenulum-piercing
#12
Gary Ventolini, Peihsuan Tsai, Lee David Moore
Candida spp. are opportunistic unicellular fungi, known to cause oral, vaginal, lung and occasionally systemic infections. Characteristically, they colonize the oral cavity, the mucosal surfaces of the cheek, palate, and tongue. Usually harmless, oral Candidas may become pathogenic under immunosuppressive conditions, dentures presence, or salivary flow impairment. Accurate species identification is important because C. dubliniensis can rapidly develop fluconazole resistance. We report C. dubliniensis in an immunocompetent patient with a metal lingual frenulum piercing...
December 2016: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28011958/cationic-porphyrin-mediated-photodynamic-inactivation-of-candida-biofilms-and-the-effect-of-miconazole
#13
A Davies, S Gebremedhin, M Yee, R J Padilla, N Duzgunes, K Konopka, B Dorocka-Bobkowska
The formation of biofilms by Candida and the increasing resistance of Candida species to antifungals contribute to the high recurrence rates of denture stomatitis. This increase has stimulated an interest in antimicrobial photodynamic therapy (aPDT) as an alternative treatment. We examined the photoactivity of the porphyrin-based photosensitizer, TMP-1363, against biofilms of C. albicans, C. glabrata, C. tropicalis and C. parapsilosis, and the effect of the combined use of miconazole and aPDT. Biofilms of three American Type Culture Collection (ATCC) strains and four clinical isolates developed on poly(methyl methacrylate) (PMMA) disks, were incubated with miconazole, followed by treatment with TMP-1363 for 30 min at 37°C...
October 2016: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/27999492/evaluation-of-denture-related-factors-predisposing-to-denture-stomatitis-in-a-lebanese-population
#14
Georges Aoun, Antoine Cassia
BACKGROUND: Denture stomatitis is a common fungal oral infection of multifactorial etiology. Denture-related factors such as denture's age, hygiene, night wearing and colonization by Candida albicans are known to predispose to denture stomatitis. The aim of this study was to evaluate these factors and their relationship with the occurrence of denture stomatitis in a Lebanese population. MATERIAL AND METHODS: Sixty patients (40 women, 20 men; age range 40-80 years) showing clinical evidence of denture-related stomatitis were selected for this study...
October 2016: Materia Socio-medica
https://www.readbyqxmd.com/read/27974977/total-cad-cam-supported-method-for-manufacturing-removable-complete-dentures
#15
Arthur Furtado de Mendonça, Mario Furtado de Mendonça, George Shelby White, Georges Sara, Darren Littlefair
The incorporation of computer-aided design/computer-aided manufacturing (CAD/CAM) technology into complete denture fabrication brings about several advantages to the fabrication process, providing better predictability of the desired outcomes and high accuracy of denture fit, mainly because the milling of prepolymerized acrylic resin eliminates the shrinkage of the acrylic base. Also, there is a decrease in the porosity when compared to a conventionally processed denture, and consequently there is a decrease in the retention of Candida albicans on the denture base...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27942552/susceptibility-of-candida-albicans-and-candida-dubliniensis-to-photodynamic-therapy-using-four-dyes-as-the-photosensitizer
#16
Nasim Hosseini, Samira Yazdanpanah, Maryam Saki, Fahimeh Rezazadeh, Janan Ghapanchi, Kamiar Zomorodian
STATEMENT OF THE PROBLEM: Oral candidiasis is the most common opportunistic infection affecting the human oral cavity. Photodynamic therapy, as one of its proposed treatment modalities, needs a distinct dye for achieving the best effect. PURPOSE: The purpose of this study was to evaluate photosensitization effects of four distinct dyes on standard suspension of Candida albicans (C. albicans) and Candida dubliniensis (C. dubliniensis) and biofilm of C. albicans considering the obtained optimum dye concentration and duration of laser irradiation...
December 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27927282/effect-of-sodium-hypochlorite-and-ricinus-communis-solutions-on-control-of-denture-biofilm-a-randomized-crossover-clinical%C3%A2-trial
#17
Carolina Noronha Ferraz de Arruda, Marcela Moreira Salles, Maurício Malheiros Badaró, Viviane de Cássia Oliveira, Ana Paula Macedo, Cláudia Helena Silva-Lovato, Helena de Freitas Oliveira Paranhos
STATEMENT OF PROBLEM: The prevalence of complete edentulism remains high in the elderly, and previous data have shown that poor denture hygiene is common among edentulous patients. PURPOSE: The purpose of this randomized crossover trial was to evaluate the efficacy of denture cleansers in terms of biofilm removal, antimicrobial action, and the remission of denture stomatitis. MATERIAL AND METHODS: Fifty denture wearers with denture stomatitis were instructed to brush their dentures (brush and soap) and to soak them (20 minutes/14 days) in 4 solutions, as follows: C (control), 0...
December 4, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27927053/future-therapies-targeted-towards-eliminating-candida-biofilms-and-associated-infections
#18
H M H N Bandara, V H Matsubara, L P Samaranayake
Candida species are common human commensals and cause either superficial or invasive opportunistic infections. The biofilm form of candida as opposed to its suspended, planktonic form, is predominantly associated with these infections. Alternative or adjunctive therapies are urgently needed to manage Candida infections as the currently available short arsenal of antifungal drugs has been compromised due to their systemic toxicity, cross-reactivity with other drugs, and above all, by the emergence of drug-resistant Candida species due to irrational drug use...
December 16, 2016: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/27920509/correlation-between-age-and-gender-in-candida-species-infections-of-complete-denture-wearers-a-retrospective-analysis
#19
Jolanta E Loster, Aneta Wieczorek, Bartłomiej W Loster
AIM: Denture-related stomatitis is a disorder that often affects denture wearers. The purpose of this study was to evaluate the intensity, genera, and frequency of yeasts in the oral cavity of complete denture wearers in terms of subject gender and age. MATERIALS AND METHODS: Nine hundred twenty patients (307 males and 613 females) with complete upper dentures were selected for the study and divided into four age groups: ≤50 years, 51-60, 61-70, and >70 years...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27915298/multilocus-sequence-typing-mlst-analysis-of-candida-albicans-isolates-colonizing-acrylic-dentures-before-and-after-denture-replacement
#20
Khai How Choo, Hee Ji Lee, Nicholas J Knight, Ann R Holmes, Richard D Cannon
Yeast, in particular Candida albicans, are the principal fungal cause of denture stomatitis, and can also be present as a commensal in many individuals. Few studies, however, have examined oral retention of yeast strains over time. We analyzed the yeast present in saliva samples and from the dentures of 10 individuals colonized with yeast but with no signs of stomatitis, before new complete maxillary dentures were fitted and also at 1, 3, and 6 months after denture replacement. Yeast species were presumptively identified on selective agar plates and were present in nine individuals before denture replacement and in six at the 6-month time point...
December 2, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
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