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https://www.readbyqxmd.com/read/28598524/nicotine-upregulates-coaggregation-of-candida-albicans-and-streptococcus-mutans
#1
Ali Ashkanane, Grace F Gomez, John Levon, L Jack Windsor, George J Eckert, Richard L Gregory
PURPOSE: Denture stomatitis is a condition of painless inflammation of denture-bearing mucosa. Reports indicate that nicotine, the major psychoactive ingredient in tobacco, increases growth of Streptococcus mutans and Candida albicans in denture biofilm. The purpose of this study was to determine the in vitro effects of nicotine on coaggregation of C. albicans with S. mutans. MATERIAL AND METHODS: C. albicans strain ATCC 10231, S. mutans strain UA159 (ATTC 700610), and nicotine dilutions (ranging from 0 to 32 mg/ml) were used for this study...
June 9, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28578870/the-essential-oil-of-allium-sativum-as-an-alternative-agent-against-candida-isolated-from-dental-prostheses
#2
Alejandro Mendoza-Juache, Saray Aranda-Romo, Josué R Bermeo-Escalona, Araceli Gómez-Hernández, Amaury Pozos-Guillén, Luis Octavio Sánchez-Vargas
BACKGROUND: The colonization of the surfaces of dental prostheses by Candida albicans is associated with the development of denture stomatitis. In this context, the use of fluconazole has been proposed, but its disadvantage is microbial resistance. Meanwhile, the oil of Allium sativum has shown an effect in controlling biofilm formation by C. albicans. AIMS: The objective of this study was to determine the antifungal activities of the essential oil of A. sativum and fluconazole against clinical isolates of Candida species obtained from rigid, acrylic-based partial or total dentures and to compare these agents' effects on both biofilm and planktonic cells...
June 1, 2017: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/28575640/the-effect-of-subinhibitory-concentrations-of-gentian-violet-on-the-germ-tube-formation-by-candida-albicans-and-its-adherence-to-oral-epithelial-cells
#3
T Mafojane, S L Shangase, M Patel
OBJECTIVE: This study investigated the effect of subinhibitory concentrations of gentian violet on the germ tube formation by Candida albicans and its adherence ability to oral epithelial cells. METHODS: Thirty strains of C. albicans isolated from denture wearers, normal healthy individuals and HIV positive patients were used in the study. The antifungal property (Minimum Fungicidal Concentration) of gentian violet was determined at various time intervals using a microdilution technique...
May 25, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28552288/fabrication-of-denture-base-materials-with-antimicrobial-properties
#4
Aysan Mirizadeh, Mohammad Atai, Sirous Ebrahimi
STATEMENT OF PROBLEM: Acrylic resin denture base resins are colonized by oral and nonoral bacteria and Candida species. This reservoir of microorganism causes denture stomatitis, which can be implicated in some life-threating infections in older denture wearers. PURPOSE: The purpose of this in vitro study was to incorporate quaternized N,N-dimethylaminoethyl methacrylate (DMAEMA) monomer into a denture base resin and investigate its antimicrobial and mechanical properties...
May 26, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28539095/effectiveness-of-non-fluoride-and-fluoride-dentifrices-for-denture-hygiene
#5
Gökçe Meriç, Meryem Güvenir, Kaya Suer
OBJECTIVE: To compare the effectiveness of commonly used herbal/non-fluoride with fluoride dentifrices in order to eliminate pathogenic oral microorganisms from denture base material. MATERIALS AND METHODS: Heat-polymerized acrylic resin specimens (n = 288) were divided into three groups and each group inoculated with three various microorganisms (n = 96 for each) Candida albicans, Staphylococcus aureus and Pseudomonas aeruginosa (P. aeruginosa). Contaminated specimens were randomly assigned to the application of six herbal/non-fluoride and three fluoride dentifrices...
May 24, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28526091/a-pre-therapeutic-coating-for-medical-devices-that-prevents-the-attachment-of-candida-albicans
#6
Diego Vargas-Blanco, Aung Lynn, Jonah Rosch, Rony Noreldin, Anthony Salerni, Christopher Lambert, Reeta P Rao
BACKGROUND: Hospital acquired fungal infections are defined as "never events"-medical errors that should never have happened. Systemic Candida albicans infections results in 30-50% mortality rates. Typically, adhesion to abiotic medical devices and implants initiates such infections. Efficient adhesion initiates formation of aggressive biofilms that are difficult to treat. Therefore, inhibitors of adhesion are important for drug development and likely to have a broad spectrum efficacy against many fungal pathogens...
May 19, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28493889/characterization-of-a-novel-antibiofilm-effect-of-nitric-oxide-releasing-aspirin-ncx-4040-on-candida-albicans-isolates-from-denture-stomatitis-patients
#7
Francisco Madariaga-Venegas, Roberto Fernández-Soto, Luisa Fernanda Duarte, Nicole Suarez, Daniela Delgadillo, José A Jara, Ricardo Fernández-Ramires, Blanca Urzúa, Alfredo Molina-Berríos
Candida albicans biofilms play a key role in denture stomatitis, one of the most common oral pathologies in elderly people. Because biofilms are highly resistant to antifungals, new pharmacological strategies are needed. Aspirin and nitric oxide-donor molecules have both shown antibiofilm effects on C. albicans, making them promising candidates for treatment. In this study, we evaluated the antifungal/antibiofilm effect of a nitric-oxide releasing aspirin (NO-ASA) on C. albicans isolates from denture stomatitis patients in vitro...
2017: PloS One
https://www.readbyqxmd.com/read/28492744/surface-properties-of-temporary-soft-liners-modified-by-minimum-inhibitory-concentrations-of-antifungals
#8
Mírian Galvão Bueno, Elen Juliana Bonassa de Sousa, Juliana Hotta, Vinícius Carvalho Porto, Vanessa Migliorini Urban, Karin Hermana Neppelenbroek
Evaluating the addition of minimum inhibitory concentrations (MICs) of antifungals for Candida albicans biofilm on the hardness and roughness of temporary denture soft liners. Specimens (n=8; 36×7×6 mm) of tissue conditioner (Softone) and resilient liner (Trusoft) were produced either without (control) or with incorporation of drugs at MICs: nystatin (0.032 g/mL), chlorhexidine diacetate (0.064 g/mL), ketoconazole (0.128 g/mL), miconazole (0.256 g/mL) and itraconazole (0.256 g/mL). Specimens were stored in distilled water at 37 °C for 24 h, 7 days and 14 days prior to the hardness/roughness measurements...
January 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28484255/the-antifungal-effects-and-mechanical-properties-of-silver-bromide-cationic-polymer-nano-composite-modified-poly-methyl-methacrylate-based-dental-resin
#9
Yu Zhang, Yin-Yan Chen, Li Huang, Zhi-Guo Chai, Li-Juan Shen, Yu-Hong Xiao
Poly-methyl methacrylate (PMMA)-based dental resins with strong and long-lasting antifungal properties are critical for the prevention of denture stomatitis. This study evaluated the antifungal effects on Candida albicans ATCC90028, the cytotoxicity toward human dental pulp cells (HDPCs), and the mechanical properties of a silver bromide/cationic polymer nano-composite (AgBr/NPVP)-modified PMMA-based dental resin. AgBr/NPVP was added to the PMMA resin at 0.1, 0.2, and 0.3 wt%, and PMMA resin without AgBr/NPVP served as the control...
May 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28476133/improving-practice-guidelines-for-the-treatment-of-denture-related-erythematous-stomatitis-a-study-protocol-for-a-randomized-controlled-trial
#10
Raphael F de Souza, Muhammad Faheem Khiyani, Carolina A L Chaves, Jocelyne Feine, Jean Barbeau, Ramón Fuentes, Eduardo Borie, Luciana C Crizostomo, Claudia H Silva-Lovato, Pierre Rompre, Elham Emami
BACKGROUND: Denture-related erythematous stomatitis (DES) is a chronic biofilm-mediated disease, affecting one in every three complete denture wearers. Antifungals are the treatment most commonly prescribed by oral health professionals, based on the belief that colonization by Candida spp. is the main cause of DES. However, high recurrence rates and adverse effects are commonly observed, prompting the need for practice guidelines regarding treatment. Results from our pilot study demonstrate that palatal brushing can reduce the palatal inflammation and potentially associated Candida carriage without any need for antifungal therapy...
May 5, 2017: Trials
https://www.readbyqxmd.com/read/28473808/the-anti-adhesive-effect-of-curcumin-on-candida-albicans-biofilms-on-denture-materials
#11
Hasanain Alalwan, Ranjith Rajendran, David F Lappin, Emilie Combet, Muhammad Shahzad, Douglas Robertson, Christopher J Nile, Craig Williams, Gordon Ramage
The use of natural compounds as an alternative source of antimicrobials has become a necessity given the growing concern over global antimicrobial resistance. Polyphenols, found in various edible plants, offers one potential solution to this. We aimed to investigate the possibility of using curcumin within the context of oral health as a way of inhibiting and preventing the harmful development of Candida albicans biofilms. We undertook a series of adsorption experiments with varying concentrations of curcumin, showing that 50 μg/ml could prevent adhesion...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28460191/early-adhesion-of-candida-albicans-onto-dental-acrylic-surfaces
#12
S Aguayo, H Marshall, J Pratten, D Bradshaw, J S Brown, S R Porter, D Spratt, L Bozec
Denture-associated stomatitis is a common candidal infection that may give rise to painful oral symptoms, as well as be a reservoir for infection at other sites of the body. As poly (methyl methacrylate) (PMMA) remains the main material employed in the fabrication of dentures, the aim of this research was to evaluate the adhesion of Candida albicans cells onto PMMA surfaces by employing an atomic force microscopy (AFM) single-cell force spectroscopy (SCFS) technique. For experiments, tipless AFM cantilevers were functionalized with PMMA microspheres and probed against C...
April 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28454505/equisetum-giganteum-influences-the-ability-of-candida-albicans-in-forming-biofilms-over-the-denture-acrylic-resin-surface
#13
Rafaela Alves da Silva, Laura Pozato Bernardo, Jessica Monique Lopes Moreno, Vanessa Soares Lara, Vinicius Carvalho Porto
CONTEXT: Equisetum giganteum L. (Equisetaceae) is an endemic plant of Central and South America used in traditional medicine. Natural drugs have been frequently used in the treatment of a myriad of diseases, proving to be an alternative to synthetic chemicals, and have been intensively studied in the prevention of sicknesses, including oral diseases. OBJECTIVE: This study evaluated the in vitro antiadherent activity of E. giganteum extract against Candida albicans biofilms...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28434686/effects-of-trimethylsilane-plasma-coating-on-the-hydrophobicity-of-denture-base-resin-and-adhesion-of-candida-albicans-on-resin-surfaces
#14
Tianshuang Liu, Changqi Xu, Liang Hong, Franklin Garcia-Godoy, Timothy Hottel, Jegdish Babu, Qingsong Yu
STATEMENT OF PROBLEM: Candida-associated denture stomatitis is the most common oral mucosal lesion among denture wearers. Trimethylsilane (TMS) plasma coating may inhibit the growth of Candida albicans on denture surfaces. PURPOSE: The purpose of this in vitro study was to investigate whether TMS plasma coatings can effectively reduce C albicans adhesion on denture base acrylic resin surfaces. MATERIAL AND METHODS: Sixty denture base acrylic resin disks with smooth and rough surfaces were prepared and were either left untreated (control group) or coated with TMS monomer (experimental group) by using plasma...
April 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28396692/efficacy-of-propolis-on-the-denture-stomatitis-treatment-in-older-adults-a-multicentric-randomized-trial
#15
Gisela de M S Pina, Erica N Lia, Andresa A Berretta, Andresa P Nascimento, Elina C Torres, Andrei F M Buszinski, Tatiana A de Campos, Eduardo B Coelho, Vicente de P Martins
Our hypothesis tested the efficacy and safety of a mucoadhesive oral gel formulation of Brazilian propolis extract compared to miconazole oral gel for the treatment of denture stomatitis due to Candida spp. infection in older adults. Forty patients were randomly allocated in a noninferiority clinical trial into two groups. The control group (MIC) received 20 mg/g miconazole oral gel and the study group (PROP) received mucoadhesive formulation containing standardized extract of 2% (20 mg/g) propolis (EPP-AF®) during 14 days...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28396001/creating-durable-and-esthetic-gingival-anatomy-on-a-polyoxymethylene-overdenture-by-using-a-chairside-procedure
#16
Gary R Login
BACKGROUND AND OVERVIEW: Snap-On Smile (DenMat) appliances are tooth-borne overdentures used for a variety of temporary esthetic applications. However, their benefit can be limited in patients with high smile lines and altered gingival architecture because the teeth look too large. CASE DESCRIPTION: In this report, the author shows the chairside application of a silicone denture reline material used to recreate gingival anatomy on an overdenture fabricated from crystallized acetyl resin, the material used in a Snap-On Smile appliance...
April 7, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28392692/antifungal-optical-and-mechanical-properties-of-polymethylmethacrylate-material-incorporated-with-silanized-zinc-oxide-nanoparticles
#17
Krid Kamonkhantikul, Mansuang Arksornnukit, Hidekazu Takahashi
BACKGROUND: Fungal infected denture, which is typically composed of polymethylmethacrylate (PMMA), is a common problem for a denture wearer, especially an elderly patient with limited manual dexterity. Therefore, increasing the antifungal effect of denture by incorporating surface modification nanoparticles into the PMMA, while retaining its mechanical properties, is of interest. AIM OF THE STUDY: This study aimed to evaluate antifungal, optical, and mechanical properties of heat-cured PMMA incorporated with different amounts of zinc oxide nanoparticles (ZnOnps) with or without methacryloxypropyltrimethoxysilane modification...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28346730/cheese-supplemented-with-probiotics-reduced-the-candida-levels-in-denture-wearers-rct
#18
Tatiana Yuriko Miyazima, Karin Hitomi Ishikawa, Marcia Pinto Alves Mayer, Susana Marta Isay Saad, Atlas Edson Moleros Nakamae
OBJETIVES: The access to probiotics should be facilitated in order to encourage their usage. We evaluated the effect of consumption of two experimental probiotic-containing cheese on the oral colonization of Candida in denture wearers. METHODS: Sixty denture wearers harboring oral Candida were randomly allocated in groups who received cheese supplemented with Lactobacillus acidophilus NCFM (T1) or Lactobacillus rhamnosus Lr-32 (T2), daily for 8 weeks, and a control group (C) who received a control cheese...
March 27, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28321584/antimicrobial-efficacy-and-mechanical-properties-of-bac-modified-hard-and-soft-denture-liners
#19
Pinar Altinci, Murat Mutluay, Eva Söderling, Arzu Tezvergil-Mutluay
This study investigated the antimicrobial efficacy and mechanical strength of hard and soft denture liners modified with benzalkonium chloride (BAC). The specimens (1 mm thickness, 8 mm diameter) were prepared by mixing 0.5, 1, 2 and 5 wt% BAC with soft (Sofreliner Medium, Tokuyama) and hard (Rebase II, Tokuyama) denture liners (n = 5/group). BAC was not added to the controls. Candida albicans ATCC 28366 (A 550 = 0.5) and Streptococcus mutans Ingbritt suspensions (A 550 = 0.35) were pipetted onto the specimens, and incubated for 4 h...
March 20, 2017: Odontology
https://www.readbyqxmd.com/read/28300045/-nature-cures-an-alternative-herbal-formulation-as-a-denture-cleanser
#20
RANDOMIZED CONTROLLED TRIAL
R Sushma, Tanuja Tanaji Sathe, Anand Farias, Pronob Kumar Sanyal, Shashi Kiran
BACKGROUND: Candida albicans is one of the microorganisms which harbor the oral cavity, especially in elderly. However, the incidence of existence of this increases in patients using removable dental prosthesis. There is therefore a need to test the anticandidal efficacy of these cost-effective, easily available products to be used as routine denture cleansers. AIM AND OBJECTIVES: (1) To evaluate antifungal properties of triphala churna on the heat cure denture base material...
January 2017: Annals of African Medicine
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