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https://www.readbyqxmd.com/read/28335569/a-quantitative-risk-assessment-model-involving-frequency-and-threat-degree-under-line-of-business-services-for-infrastructure-of-emerging-sensor-networks
#1
Xu Jing, Hanwen Hu, Huijun Yang, Man Ho Au, Shuqin Li, Naixue Xiong, Muhammad Imran, Athanasios V Vasilakos
The prospect of Line-of-Business Services (LoBSs) for infrastructure of Emerging Sensor Networks (ESNs) is exciting. Access control remains a top challenge in this scenario as the service provider's server contains a lot of valuable resources. LoBSs' users are very diverse as they may come from a wide range of locations with vastly different characteristics. Cost of joining could be low and in many cases, intruders are eligible users conducting malicious actions. As a result, user access should be adjusted dynamically...
March 21, 2017: Sensors
https://www.readbyqxmd.com/read/28335500/comparison-of-two-types-of-overoxidized-pedot-films-and-their-application-in-sensor-fabrication
#2
Yun Hui, Chao Bian, Jinfen Wang, Jianhua Tong, Shanhong Xia
Poly(3,4-ethylenedioxythiophene) (PEDOT) films were prepared by electro-oxidation on Au microelectrodes in an aqueous solution. Electrolyte solutions and polymerization parameters were optimized prior to overoxidation. The effect of overoxidation time has been optimized by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), which results in the film overoxidized for 45 s at 1.35 V presenting a strong adsorption. The other one-step overoxidation film prepared by direct CV ranging from -0...
March 19, 2017: Sensors
https://www.readbyqxmd.com/read/28335348/electrochemical-synthesis-of-polypyrrole-reduced-graphene-oxide-and-gold-nanoparticles-composite-and-its-application-to-hydrogen-peroxide-biosensor
#3
Baoyan Wu, Na Zhao, Shihua Hou, Cong Zhang
Here we report a facile eco-friendly one-step electrochemical approach for the fabrication of a polypyrrole (PPy), reduced graphene oxide (RGO), and gold nanoparticles (nanoAu) biocomposite on a glassy carbon electrode (GCE). The electrochemical behaviors of PPy-RGO-nanoAu and its application to electrochemical detection of hydrogen peroxide were investigated by cyclic voltammetry. Graphene oxide and pyrrole monomer were first mixed and casted on the surface of a cleaned GCE. After an electrochemical processing consisting of the electrooxidation of pyrrole monomer and simultaneous electroreduction of graphene oxide and auric ions (Au(3+)) in aqueous solution, a PPy-RGO-nanoAu biocomposite was synthesized on GCE...
November 21, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335336/oral-toxicity-and-intestinal-transport-mechanism-of-colloidal-gold-nanoparticle-treated-red-ginseng
#4
Song-Hwa Bae, Jin Yu, Mi-Ran Go, Hyun-Jin Kim, Yun-Gu Hwang, Soo-Jin Choi
(1) Background: Application of nanotechnology or nanomaterials in agricultural food crops has attracted increasing attention with regard to improving crop production, quality, and nutrient utilization. Gold nanoparticles (Au-NPs) have been reported to enhance seed yield, germination rate, and anti-oxidant potential in food crops, raising concerns about their toxicity potential. In this study, we evaluated the oral toxicity of red ginseng exposed to colloidal Au-NPs during cultivation (G-red ginseng) in rats and their intestinal transport mechanism...
November 11, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335199/highly-efficient-plasmon-enhanced-dye-sensitized-solar-cells-created-by-means-of-dry-plasma-reduction
#5
Van-Duong Dao, Ho-Suk Choi
Plasmon-assisted energy conversion is investigated in a comparative study of dye-sensitized solar cells (DSCs) equipped with photo-anodes, which are fabricated by forming gold (Au) and silver (Ag) nanoparticles (NPs) on an fluorine-doped tin oxide (FTO) glass surface by means of dry plasma reduction (DPR) and coating TiO₂ paste onto the modified FTO glass through a screen printing method. As a result, the FTO/Ag-NPs/TiO₂ photo-anode showed an enhancement of its photocurrent, whereas the FTO/Au-NPs/TiO₂ photo-anode showed less photocurrent than even a standard photo-anode fabricated by simply coating TiO₂ paste onto the modified FTO glass through screen printing...
April 14, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335196/gold-nanomaterial-uptake-from-soil-is-not-increased-by-arbuscular-mycorrhizal-colonization-of-solanum-lycopersicum-tomato
#6
Jonathan D Judy, Jason K Kirby, Mike J McLaughlin, Timothy Cavagnaro, Paul M Bertsch
Bioaccumulation of engineered nanomaterials (ENMs) by plants has been demonstrated in numerous studies over the past 5-10 years. However, the overwhelming majority of these studies were conducted using hydroponic systems and the degree to which the addition of the biological and chemical components present in the soil might fundamentally alter the potential of plant bioaccumulation of ENMs is unclear. Here, we used two genotypes of Solanum lycopersicum (tomato), reduced mycorrhizal colonization (rmc), a mutant which does not allow arbuscular mycorrhizal fungi (AMF) colonization, and its progenitor, 76R, to examine how colonization by AMF alters trends of gold ENM bioaccumulation from a natural soil...
April 13, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335193/facile-synthesis-of-gd-functionalized-gold-nanoclusters-as-potential-mri-ct-contrast-agents
#7
Wenjun Le, Shaobin Cui, Xin Chen, Huanhuan Zhu, Bingdi Chen, Zheng Cui
Multi-modal imaging plays a key role in the earlier detection of disease. In this work, a facile bioinspired method was developed to synthesize Gd-functionalized gold nanoclusters (Gd-Au NCs). The Gd-Au NCs exhibit a uniform size, with an average size of 5.6 nm in dynamic light scattering (DLS), which is a bit bigger than gold clusters (3.74 nm, DLS), while the fluorescent properties of Gd-Au NCs are almost the same as that of Au NCs. Moreover, the Gd-Au NCs exhibit a high longitudinal relaxivity value (r1) of 22...
April 9, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334983/gwas-linked-ppargc1a-variant-in-asian-patients-with-essential-tremor
#8
Bin Xiao, Xiao Deng, Ebonne Yu-Lin Ng, Murni Tio, Kumar M Prakash, Wing Lok Au, Louis Tan, Yi Zhao, Eng-King Tan
No abstract text is available yet for this article.
February 20, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28334976/a-sensitivity-analysis-of-rna-folding-nearest-neighbor-parameters-identifies-a-subset-of-free-energy-parameters-with-the-greatest-impact-on-rna-secondary-structure-prediction
#9
Jeffrey Zuber, Hongying Sun, Xiaoju Zhang, Iain McFadyen, David H Mathews
Nearest neighbor parameters for estimating the folding energy changes of RNA secondary structures are used in structure prediction and analysis. Despite their widespread application, a comprehensive analysis of the impact of each parameter on the precision of calculations had not been conducted. To identify the parameters with greatest impact, a sensitivity analysis was performed on the 291 parameters that compose the 2004 version of the free energy nearest neighbor rules. Perturbed parameter sets were generated by perturbing each parameter independently...
March 15, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28334781/auf1-facilitates-microrna-mediated-gene-silencing
#10
Kyung-Won Min, Myung Hyun Jo, Soochul Shin, Sylvia Davila, Richard W Zealy, Soo Im Kang, Lawson T Lloyd, Sungchul Hohng, Je-Hyun Yoon
Eukaryotic mRNA decay is tightly modulated by RNA-binding proteins (RBPs) and microRNAs (miRNAs). RBP AU-binding factor 1 (AUF1) has four isoforms resulting from alternative splicing and is critical for miRNA-mediated gene silencing with a distinct preference of target miRNAs. Previously, we have shown that AUF1 facilitates miRNA loading to Argonaute 2 (AGO2), the catalytic component of the RNA-induced silencing complex. Here, we further demonstrate that depletion of AUF1 abolishes the global interaction of miRNAs and AGO2...
February 28, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28334704/combining-real-time-cold-and-mama-pcr-taqman-techniques-to-detect-and-quantify-r201-gnas-mutations-in-the-mccune-albright-syndrome%C3%A2
#11
Luisa de Sanctis, Ilaria Galliano, Paola Montanari, Patrizia Matarazzo, Daniele Tessaris, Massimiliano Bergallo
BACKGROUND/AIM: The McCune-Albright syndrome (MAS) is a potentially severe disorder hallmarked by fibrous bone dysplasia, café-au-lait skin spots, and endocrine hyperfunction. It is caused by postzygotic activating mutations at the R201 codon of the GNAS gene, leading to a state of somatic mosaicism. Our aim was to improve the mutation detection rate and to quantify the presence of R201 GNAS mutations in different DNA samples from MAS patients. METHODS: Real-time COLD- and MAMA-PCR TaqMan techniques were combined to search for R201 mutations in the DNA of blood or affected tissues from 16 previously molecularly characterized MAS patients, from a further 84 subjects with MAS signs who were R201 negative at RFLP analysis, and from 36 controls...
March 23, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28334692/sers-active-liposome-ag-au-nanocomposite-for-nir-light-driven-drug-release
#12
Yangyang Zhao, Jing Zhao, Guiye Shan, Dongmei Yan, Yanwei Chen, Yichun Liu
It is important to control drug release and detect the distribution of drug molecules before and after release. In this work, liposome@AgAu nanocomposite is prepared for drug delivery, which not only can control drug release by near infrared laser irradiation but also can monitor drug molecules by surface enhanced Raman scattering (SERS) and fluorescence signal during the release process. The liposome@AgAu core/shell nanocomposite prepared by the galvanic replacement reaction (GRR) shows tunable localized surface plasmon resonance (LSPR) absorption peaks from visible to near-infrared region and good biocompatibility...
March 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28334662/the-association-between-personality-disorders-with-alcohol-use-and-misuse-a-population-based-twin-study
#13
E C Long, S H Aggen, M C Neale, G P Knudsen, R F Krueger, S C South, N Czajkowski, R Nesvåg, E Ystrom, F A Torvik, K S Kendler, N A Gillespie, T Reichborn-Kjennerud
BACKGROUND: A clearer understanding of the etiological overlap between DSM-IV personality disorders (PDs) and alcohol use (AU) and alcohol use disorder (AUD) is needed. To our knowledge, no study has modeled the association between all 10 DSM-IV PDs and lifetime AU and AUD. The aim of the present study is to identify which PDs are most strongly associated with the phenotypic, genetic, and environmental risks of lifetime AU and AUD, and to determine if these associations are stable across time...
March 7, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28334120/svpv-a-structural-variant-prediction-viewer-for-paired-end-sequencing-datasets
#14
Jacob E Munro, Sally L Dunwoodie, Eleni Giannoulatou
Motivation: A wide range of algorithms exist for the prediction of structural variants (SVs) from paired-end whole genome sequencing (WGS) alignments. It is essential for the purpose of quality control to be able to visualize, compare and contrast the data underlying the predictions across multiple different algorithms. Results: We provide the structural variant prediction viewer, a tool which presents a visual summary of the most relevant features for SV prediction from WGS data...
February 27, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28334108/fast-admixture-analysis-and-population-tree-estimation-for-snp-and-ngs-data
#15
Yu Jade Cheng, Thomas Mailund, Rasmus Nielsen
Structure methods are highly used population genetic methods for classifying individuals in a sample fractionally into discrete ancestry components. We introduce a new optimization algorithm for the classical STRUCTURE model in a maximum likelihood framework. Using analyses of real data we show that the new method finds solutions with higher likelihoods than the state-of-the-art method inthe same computational time. The optimization algorithm is also applicable to models based on genotype likelihoods, that can account for the uncertainty in genotype-calling associated with Next Generation Sequencing (NGS) data...
February 17, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28333964/optimizing-ultrasound-molecular-imaging-of-secreted-frizzled-related-protein-2-expression-in-angiosarcoma
#16
James K Tsuruta, Nicholas P Schaub, Juan D Rojas, Jason Streeter, Nancy Klauber-DeMore, Paul Dayton
Secreted frizzled related protein 2 (SFRP2) is a tumor endothelial marker expressed in angiosarcoma. Previously, we showed ultrasound molecular imaging with SFRP2-targeted contrast increased average video pixel intensity (VI) of angiosarcoma vessels by 2.2 ± 0.6 VI versus streptavidin contrast. We hypothesized that redesigning our contrast agents would increase imaging performance. Improved molecular imaging reagents were created by combining NeutrAvidin™-functionalized microbubbles with biotinylated SFRP2 or IgY control antibodies...
2017: PloS One
https://www.readbyqxmd.com/read/28333956/discriminating-between-hur-and-ttp-binding-sites-using-the-k-spectrum-kernel-method
#17
Shweta Bhandare, Debra S Goldberg, Robin Dowell
BACKGROUND: The RNA binding proteins (RBPs) human antigen R (HuR) and Tristetraprolin (TTP) are known to exhibit competitive binding but have opposing effects on the bound messenger RNA (mRNA). How cells discriminate between the two proteins is an interesting problem. Machine learning approaches, such as support vector machines (SVMs), may be useful in the identification of discriminative features. However, this method has yet to be applied to studies of RNA binding protein motifs. RESULTS: Applying the k-spectrum kernel to a support vector machine (SVM), we first verified the published binding sites of both HuR and TTP...
2017: PloS One
https://www.readbyqxmd.com/read/28333943/fabrication-of-sensitive-enzymatic-biosensor-based-on-multi-layered-reduced-graphene-oxide-added-ptau-nanoparticles-modified-hybrid-electrode
#18
Md Faruk Hossain, Jae Y Park
A highly sensitive amperometric glucose sensor was developed by immobilization of glucose oxidase (GOx) onto multi-layer reduced graphene oxide (MRGO) sheets decorated with platinum and gold flower-like nanoparticles (PtAuNPs) modified Au substrate electrode. The fabricated MRGO/PtAuNPs modified hybrid electrode demonstrated high electrocatalytic activities toward oxidation of H2O2, to which it had a wide linear response that ranged from 0.5 to 8 mM (R2 = 0.997), and high sensitivity of 506.25 μA/mMcm2. Furthermore, glucose oxidase-chitosan composite and cationic polydiallyldimethylammonium chloride (PDDA) were assembled by a casting method on the surface of MRGO/PtAuNPs modified electrode...
2017: PloS One
https://www.readbyqxmd.com/read/28333441/direct-chemical-vapor-deposition-growth-and-band-gap-characterization-of-mos2-h-bn-van-der-waals-heterostructures-on-au-foils
#19
Zhepeng Zhang, Xujing Ji, Jianping Shi, Xiebo Zhou, Shuai Zhang, Yue Hou, Yue Qi, Qiyi Fang, Qingqing Ji, Yu Zhang, Min Hong, Pengfei Yang, Xinfeng Liu, Qing Zhang, Lei Liao, Chuanhong Jin, Zhongfan Liu, Yanfeng Zhang
Stacked transition-metal dichalcogenides on hexagonal boron nitride (h-BN) are platforms for high-performance electronic devices. However, such vertical stacks are usually constructed by the layer-by-layer polymer-assisted transfer of mechanically exfoliated layers. This inevitably causes interfacial contamination and device performance degradation. Herein, we develop a two-step, low-pressure chemical vapor deposition synthetic strategy incorporating the direct growth of monolayer h-BN on Au foil with the subsequent growth of MoS2...
March 23, 2017: ACS Nano
https://www.readbyqxmd.com/read/28332814/hf-free-electroless-deposition-of-metals-on-silicon-in-ionic-liquids-and-its-enhanced-performance-in-lithium-storage
#20
Abhishek Lahiri, Tianqi Lu, Niklas Behrens, Natalia Borisenko, Guozhu Li, Frank Endres
Metal nanoparticles such as Au, Ag, Pt etc. have been deposited on silicon by electroless deposition in the presence of HF for applications such as oxygen reduction reaction, surface enhanced Raman spectroscopy as well as for lithium ion batteries. Here, we show a HF-free process wherein metals such as Sb and Ag could be deposited onto electrodeposited silicon in ionic liquids. We further show that compared to electrodeposited silicon, Sb modified Si demonstrates a better performance for lithium storage. The present study opens up new paradigm for electroless deposition technique in ionic liquids for developing and modifying functional materials...
March 23, 2017: ACS Applied Materials & Interfaces
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