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https://www.readbyqxmd.com/read/29791963/nerve-entrapment-in-ankle-and-foot-ultrasound-imaging
#1
Basavaraj Chari, Eugene McNally
Peripheral nerve entrapment of the ankle and foot is relatively uncommon and often underdiagnosed because electrophysiologic studies may not contribute to the diagnosis. Anatomy of the peripheral nerves is variable and complex, and along with a comprehensive physical examination, a thorough understanding of the applied anatomy is essential. Several studies have helped identify specific areas in which nerves are commonly compressed. Identified secondary causes of nerve compression include previous trauma, osteophytes, ganglion cysts, edema, accessory muscles, tenosynovitis, vascular lesions, and a primary nerve tumor...
July 2018: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/29608037/pain-and-structural-alterations-in-knee-joints-in-patients-with-haemophilia
#2
S Krüger, M Hoffmeister, T Hilberg
INTRODUCTION: Patients with haemophilia (PwH) suffer from haemophilic arthropathy which leads to an enhanced pain sensitivity. The aim of this study was to determine whether the individual pain condition in terms of pressure pain thresholds (PPT) at the knee joints is linked to changes of underlying anatomical structures in PwH. MATERIAL AND METHODS: Eleven landmarks at both knee joints of 36 PwH and 36 controls were examined in terms of PPT and ultrasound sonography (US)...
April 2, 2018: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29521748/delayed-diagnosis-of-gorlin-goltz-syndrome-the-importance-of-the-multidisciplinary-approach
#3
Jéssica Araújo Figueira, Fábio Roberto de Souza Batista, Karina Rosso, Vanessa Cristina Veltrini, Angelo José Pavan
Gorlin-Goltz syndrome (GGS), also known as nevoid basal cell carcinoma syndrome, is an autosomal dominant inherited disorder with high penetrance and variable expressivity. The classic triad originally described by Gorlin and Goltz in 1960 is composed of multiple nevoid basal cell carcinomas (NBCCs), odontogenic keratocysts (OKCs) in the jaws and bifid ribs. in 1977, this triad was modified by Rayner et al, and to GGS diagnosis, the OKCs had to appear in combination with calcification of the cerebellar falx or palmar and plantar pits...
March 8, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29474100/cervical-myelopathy-causing-numbness-and-paresthesias-in-lower-extremities-a-case-report-identifying-the-cause-of-a-false-positive-sharp-purser-test
#4
Cody J Mansfield
INTRODUCTION: The patient was referred to an outpatient physical therapy clinic for lumbar radiculopathy by a primary care physician and subsequently referred for imaging due to suspicion of cervical myelopathy. The case highlights the clinical reasoning of the physical therapist differentiating between lumbar stenosis, cervical myelopathy, and upper cervical instability. To the author's knowledge, this is the only case report in the literature to describe the mechanism that could underpin a false positive Sharp-Purser test (SPT)...
February 23, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29354759/a-rare-cause-of-late-onset-neurological-deficit-in-post-tuberculous-kyphotic-deformity-case-report
#5
Suresh Subramani, Ajoy Prasad Shetty, Rishi M Kanna, Shanmuganathan Rajasekaran
Late onset neurological deficit is a rare complication of spinal tuberculosis. Reactivation of the disease and compression by internal gibbus are the common causes for late onset neurological deficit. We report a rare cause of late onset paraplegia in a patient with post tubercular kyphotic deformity. The late onset neurological deficit was due to the adjacent segment degeneration proximal to the kyphotic deformity. Posterior hypertrophied ligamentum flavum and anterior disc osteophyte complex caused the cord compression...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28934396/evaluation-of-shared-genetic-aetiology-between-osteoarthritis-and-bone-mineral-density-identifies-smad3-as-a-novel-osteoarthritis-risk-locus
#6
Sophie Hackinger, Katerina Trajanoska, Unnur Styrkarsdottir, Eleni Zengini, Julia Steinberg, Graham R S Ritchie, Konstantinos Hatzikotoulas, Arthur Gilly, Evangelos Evangelou, John P Kemp, David Evans, Thorvaldur Ingvarsson, Helgi Jonsson, Unnur Thorsteinsdottir, Kari Stefansson, Andrew W McCaskie, Roger A Brooks, Jeremy M Wilkinson, Fernando Rivadeneira, Eleftheria Zeggini
Osteoarthritis (OA) is a common complex disease with high public health burden and no curative therapy. High bone mineral density (BMD) is associated with an increased risk of developing OA, suggesting a shared underlying biology. Here, we performed the first systematic overlap analysis of OA and BMD on a genome wide scale. We used summary statistics from the GEFOS consortium for lumbar spine (n = 31,800) and femoral neck (n = 32,961) BMD, and from the arcOGEN consortium for three OA phenotypes (hip, ncases=3,498; knee, ncases=3,266; hip and/or knee, ncases=7,410; ncontrols=11,009)...
October 1, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28865213/injection-in-temporomandibular-joint-of-rats-description-of-technical-protocol
#7
R Fuentes, C Veuthey, A Arias, D Saravia, N E Ottone
The development of animal models for research has been very diffused. Osteoarthritis is a joint degenerative pathology that induces cartilage erosion, chondrocyte proliferation and osteophyte formation. The aim of this paper is to present a technical procedure to perform the injection of monosodium iodine acetate in the temporomandibular joints of rats to generate osteoarthritis and to contribute to future research analysis related to pathology progression and proper treatment performance. The use of rat models may be a complex process because of their size, but they can be compared to the human temporomandibular joint due to the similar characteristics and the possibility of performing diagnosis and treatment protocols in order to detect this pathology...
March 1, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28765801/regression-of-disc-osteophyte-complexes-following-laminoplasty-versus-laminectomy-with-fusion-for-cervical-spondylotic-myelopathy
#8
Remi M Ajiboye, Stephen D Zoller, Adedayo A Ashana, Akshay Sharma, William Sheppard, Langston T Holly
BACKGROUND: Laminectomy with fusion (LF) and laminoplasty are two posterior-based surgical approaches for the surgical treatment of cervical spondylotic myelopathy (CSM). The decompressive effect of these approaches is thought to be primarily related to the dorsal drift of the spinal cord away from ventral compressive structures. A lesser known mechanism of spinal cord decompression following cervical LF is regression of the ventral disc osteophyte complexes which is postulated to result from the alteration of motion across the fused motion segment...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28735021/wisp1-ccn4-aggravates-cartilage-degeneration-in-experimental-osteoarthritis
#9
M H van den Bosch, A B Blom, V Kram, A Maeda, S Sikka, Y Gabet, T M Kilts, W B van den Berg, P L van Lent, P M van der Kraan, M F Young
OBJECTIVE: Increased Wisp1 expression was previously reported in experimental and human osteoarthritis (OA). Moreover, adenoviral overexpression of Wisp1 in naïve mouse knee joints resulted in early OA-like cartilage lesions. Here, we determined how the matricellular protein WISP1 is involved in the pathology that occurs in the complex osteoarthritic environment with aging and experimental OA in wild type (WT) and Wisp1(-/-) mice. METHODS: WT and Wisp1(-/-) mice were aged or experimental OA was induced with intraarticular collagenase injection, destabilization of the medial meniscus (DMM) or anterior cruciate ligament transection (ACLT)...
July 19, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28525486/regression-of-anterior-disk-osteophyte-complex-following-cervical-laminectomy-and-fusion-for-cervical-spondylotic-myelopathy
#10
Adedayo O Ashana, Jeremiah R Cohen, Brandon Evans, Langston T Holly
STUDY DESIGN: A retrospective case-control study. OBJECTIVE: To investigate whether posterior cervical laminectomy and fusion modifies the natural course of anterior disk-osteophyte complex in patients with multilevel cervical spondylotic myelopathy. SUMMARY OF BACKGROUND DATA: Dorsal migration of the spinal cord is the main purported mechanism of spinal cord decompression following cervical laminectomy and fusion but other potential mechanisms have received scant attention in the literature...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28290970/severe-systemic-lead-toxicity-resulting-from-extra-articular-retained-shrapnel-presenting-as-jaundice-and-hepatitis-a-case-report-and-review-of-the-literature
#11
Ian A Grasso, Matthew R Blattner, Tyler Short, John W Downs
INTRODUCTION: Despite greater than 60,000 nonfatal firearm injuries per year in the United States, retained shrapnel is a relatively rare cause of systemic lead toxicity with less than 100 cases reported in the medical literature since 1867. While intra-articular retained shrapnel as a cause of lead toxicity is well-described, extra-articular fragments are less well known to cause symptomatic disease. CASE REPORT: A 31-year-old man initially presented with abdominal pain, constipation, jaundice, and elevated liver transaminases approximately 3 weeks after suffering a left lower extremity injury during athletic activity...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/27994778/intrinsic-vertebral-markers-for-spinal-level-localization-in-anterior-cervical-spine-surgery-a-preliminary-report
#12
Deepak Kumar Jha, Anil Thakur, Mukul Jain, Arvind Arya, Chandrabhushan Tripathi, Rima Kumari, Suman Kushwaha
STUDY DESIGN: Prospective clinical study. PURPOSE: To observe the usefulness of anterior cervical osteophytes as intrinsic markers for spinal level localization (SLL) during sub-axial cervical spinal surgery via the anterior approach. OVERVIEW OF LITERATURE: Various landmarks, such as the mandibular angle, hyoid bone, thyroid cartilage, first cricoid ring, and C6 carotid tubercle, are used for gross cervical SLL; however, none are used during cervical spinal surgery via the anterior approach...
December 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27561836/counterpoint-appropriately-ambiguous-the-disc-osteophyte-complex
#13
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
December 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27509467/unsuspected-cervical-osteophytes-and-complex-endoscopy-there-is-cause-for-concern
#14
Fabio Sbaraglia, Giorgia Spinazzola, Guido Costamagna, Maria Sammartino
No abstract text is available yet for this article.
2016: Endoscopy
https://www.readbyqxmd.com/read/27355728/regression-of-anterior-disc-osteophyte-complex-following-cervical-laminectomy-and-fusion-for-cervical-spondylotic-myelopathy
#15
Adedayo O Ashana, Jeremiah R Cohen, Brandon Evans, Langston T Holly
STUDY DESIGN: Retrospective case control study. OBJECTIVE: To investigate whether posterior cervical laminectomy and fusion modifies the natural course of anterior disc-osteophyte complex in patients with multilevel CSM. SUMMARY OF BACKGROUND DATA: Dorsal migration of the spinal cord is the main purported mechanism of spinal cord decompression following cervical laminectomy and fusion but other potential mechanisms have received scant attention in the literature...
June 28, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/26542671/effect-of-antiresorptive-and-anabolic-bone-therapy-on-development-of-osteoarthritis-in-a-posttraumatic-rat-model-of-oa
#16
Cedo M Bagi, Edwin Berryman, David E Zakur, Dean Wilkie, Catharine J Andresen
INTRODUCTION: Osteoarthritis (OA) is a leading cause of disability, but despite the high unmet clinical need and extensive research seeking dependable therapeutic interventions, no proven disease-modifying treatment for OA is currently available. Due to the close interaction and interplay between the articular cartilage and the subchondral bone plate, it has been hypothesized that antiresorptive drugs can also reduce cartilage degradation, inhibit excessive turnover of the subchondral bone plate, prevent osteophyte formation, and/or that bone anabolic drugs might also stimulate cartilage synthesis by chondrocytes and preserve cartilage integrity...
November 6, 2015: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/26458934/complex-cervical-spondylotic-myelopathy-a-report-of-two-cases-and-literature-review
#17
REVIEW
Zhuo Ma, Xun Ma, Huilin Yang, Haoyu Feng, Chen Chen
STUDY DESIGN: A report of two cases with complex cervical spondylotic myelopathy (CSM) and review of the literature. OBJECTIVE: To describe two unique patients with complex CSM due to simultaneous anomalies as anteroposterior compressions of the spinal cord in both upper and lower cervical spine, caused by hypertrophic transverse ligament of atlas (TLA), dysplasia of the posterior arch of atlas, disc herniation, hypertrophic ligamentum flavum and osteophytes. METHODS: We present such two cases with clinical, imageological presentations, and describe the surgical procedure, to which both patients responded favorably...
May 2016: European Spine Journal
https://www.readbyqxmd.com/read/26362437/differential-interactive-effects-of-cartilage-traumatization-and-blood-exposure-in-vitro-and-in-vivo
#18
Helga Joos, Frank Leucht, Jana Riegger, Cathrin Hogrefe, Jörg Fiedler, Lutz Dürselen, Heiko Reichel, Anita Ignatius, Rolf E Brenner
BACKGROUND: Sport injuries of the knee often lead to posttraumatic arthritis. In addition to direct damage of the cartilage, trauma-associated intra-articular bleeding may cause hemarthrosis. Both blood exposure and trauma are known to induce cell death and inflammation and to enhance proteoglycan release in cartilage. HYPOTHESIS: Blood exposure increases chondrocyte death as well as inflammatory and degenerative processes in traumatized cartilage. STUDY DESIGN: Controlled laboratory study...
November 2015: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/25746115/predictors-of-intramedullary-lesion-expansion-rate-on-mr-images-of-patients-with-subaxial-spinal-cord-injury
#19
Elizabeth Le, Bizhan Aarabi, David S Hersh, Kathirkamanthan Shanmuganathan, Cara Diaz, Jennifer Massetti, Noori Akhtar-Danesh
OBJECT Studies of preclinical spinal cord injury (SCI) in rodents indicate that expansion of intramedullary lesions (IMLs) seen on MR images may be amenable to neuroprotection. In patients with subaxial SCI and motor-complete American Spinal Injury Association (ASIA) Impairment Scale (AIS) Grade A or B, IML expansion has been shown to be approximately 900 μm/hour. In this study, the authors investigated IML expansion in a cohort of patients with subaxial SCI and AIS Grade A, B, C, or D. METHODS Seventy-eight patients who had at least 2 MRI scans within 6 days of SCI were enrolled...
June 2015: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/25504962/obesity-and-osteoarthritis-more-than-just-wear-and-tear-pivotal-roles-for-inflamed-adipose-tissue-and-dyslipidaemia-in-obesity-induced-osteoarthritis
#20
REVIEW
Eva Thijssen, Arjan van Caam, Peter M van der Kraan
OA is a degenerative joint disease characterized by articular cartilage degradation, osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk factors is obesity. To date, it is not fully understood how obesity results in OA. Historically, this link was ascribed to excessive joint loading as a result of increased body weight. However, the association between obesity and OA in non-weight-bearing joints suggests a more complex aetiology for obesity-induced OA. In the present review, the link between obesity and OA is discussed...
April 2015: Rheumatology
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