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endobronchial valves

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https://www.readbyqxmd.com/read/28795040/successful-treatment-of-a-giant-emphysematous-bulla-with-an-endobronchial-valve-in-a-patient-with-contralateral-lung-cancer
#1
Chang-Seok Jeon, Jhingook Kim, Hojoong Kim
Patients with severe emphysema have a higher risk of developing lung cancer, and their surgical risk increases when emphysema is accompanied by a giant bulla. Here, we describe a patient who had an emphysematous giant bulla in the right upper lobe that was treated with an endobronchial valve placement. Subsequently, a cancerous lesion on the contralateral lung was successfully removed by lobectomy.
August 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28637047/pleural-adhesion-assessment-as-a-predictor-for-pneumothorax-after-endobronchial-valve-treatment
#2
Wouter H van Geffen, Karin Klooster, Jorine E Hartman, Nick H T Ten Hacken, Huib A M Kerstjens, Rienhart F E Wolf, Dirk-Jan Slebos
BACKGROUND: Pneumothorax after bronchoscopic lung volume reduction using one-way endobronchial valves (EBVs) in patients with advanced emphysema occurs in approximately 20% of patients. It is not well known which factors predict the development of pneumothorax. OBJECTIVE: To assess whether pleural adhesions on pretreatment high-resolution computed tomography (HRCT) scans are associated with pneumothorax occurrence after EBV treatment. METHODS: HRCT scan analyses were performed on all patients who received EBV treatment in a randomized controlled trial...
2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28527920/emerging-bronchoscopic-treatments-for-chronic-obstructive-pulmonary-disease
#3
REVIEW
Wouter H van Geffen, Huib A M Kerstjens, Dirk-Jan Slebos
Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by pathophysiological factors including airflow limitation, hyperinflation and reduced gas exchange. Treatment consists of lifestyle changes, lung rehabilitation and pharmacological therapies such as long acting beta-2-agonists (LABA) and long acting muscarinic antagonists (LAMA). More recently bronchoscopic treatments are emerging for COPD. Among them endobronchial valves(EBV) and endobronchial coils (EBC), next to endobronchial stents, sclerosing agents, targeted lung denervation and liquid nitrogen metered cryospray...
May 17, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28459316/improved-predictors-of-survival-after-endobronchial-valve-treatment-in-patients-with-severe-emphysema
#4
Karin Klooster, Jorine E Hartman, Nick H T Ten Hacken, Dirk-Jan Slebos
No abstract text is available yet for this article.
May 1, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28444339/comparison-of-plethysmographic-and-helium-dilution-lung-volumes-in-patients-with-a-giant-emphysematous-bulla-as-selection-criteria-for-endobronchial-valve-implant%C3%A2
#5
Alfonso Fiorelli, Roberto Scaramuzzi, Matteo Pierdiluca, Elisabetta Frongillo, Gaetana Messina, Nicola Serra, Alberto De Felice, Mario Santini
OBJECTIVES: To assess whether the difference in lung volume measured with plethysmography and with the helium dilution technique could differentiate an open from a closed bulla in patients with a giant emphysematous bulla and could be used as a selection criterion for the positioning of an endobronchial valve. METHODS: We reviewed the data of 27 consecutive patients with a giant emphysematous bulla undergoing treatment with an endobronchial valve. In addition to standard functional and radiological examinations, total lung capacity and residual volume were measured with the plethysmographic and helium dilution technique...
April 24, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28391759/current-treatment-of-tracheoesophageal-fistula
#6
Changzhi Zhou, Yi Hu, Yang Xiao, Wen Yin
Tracheoesophageal fistulas (TEFs) often occur with esophageal or bronchial carcinoma. Currently, we rely on implantation of delicate devices, such as self-expanding and silicone stents, in the esophagus or trachea to cover the fistula and expand the stenosis in order to relieve patient pain. However, because each case is different, our approach may not be effective for every patient. Consequently, new devices and technology have emerged to address these situations, such as degradable stents, Amplatzer(®) devices, endobronchial one-way umbrella-shaped valves, and transplantation of mesenchymal stem cells...
April 2017: Therapeutic Advances in Respiratory Disease
https://www.readbyqxmd.com/read/28367339/bronchopleural-fistula-resolution-with-endobronchial-valve-placement-and-liberation-from-mechanical-ventilation-in-acute-respiratory-distress-syndrome-a-case-series
#7
Haris Kalatoudis, Meena Nikhil, Fuad Zeid, Yousef Shweihat
Patients who have acute respiratory distress syndrome (ARDS) with persistent air leaks have worse outcomes. Endobronchial valves (EBV) are frequently deployed after pulmonary resection in noncritically ill patients to reduce and eliminate bronchopleural fistulas (BPFs) with persistent air leak (PAL). Information regarding EBV placement in mechanically ventilated patients with ARDS and high volume persistent air leaks is rare and limited to case reports. We describe three cases where EBV placement facilitated endotracheal extubation in patients with severe respiratory failure on prolonged mechanical ventilation with BPFs...
2017: Case Reports in Critical Care
https://www.readbyqxmd.com/read/28355597/endobronchial-valve-used-as-salvage-therapy-in-a-mechanically-ventilated-patient-with-intractable-life-threatening-haemoptysis
#8
Usha Lalla, Brian W Allwood, Soumitra Sinha Roy, Elvis M Irusen, Coenraad F N Koegelenberg
Treatment options for intractable life-threatening haemoptysis in mechanically ventilated patients with structural lung disease who do not respond to bronchial artery embolisation (BAE) and who are deemed unfit for surgery are limited. A 26-year-old HIV-positive male with a poorly preserved CD4 count and active pulmonary tuberculosis was intubated and mechanically ventilated for persistent life-threatening haemoptysis. Two attempts at BAE failed, and life-threatening haemoptysis recurred daily for 14 days despite antituberculous therapy...
2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28323737/an-unusual-complication-of-long-term-endobronchial-valves-placed-for-persistent-air-leak
#9
Trevor M Taylor, Robert J Lentz, Fabien Maldonado
No abstract text is available yet for this article.
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28267436/management-of-persistent-air-leaks
#10
REVIEW
Karen C Dugan, Balaji Laxmanan, Septimiu Murgu, D Kyle Hogarth
Alveolar-pleural fistulas causing persistent air leaks (PALs) are associated with prolonged hospital stays and high morbidity. Prior guidelines recommend surgical repair as the gold standard for treatment, albeit it is a solution with limited success. In patients who have recently undergone thoracic surgery or in whom surgery would be contraindicated based on the severity of illness, there has been a lack of treatment options. This review describes a brief history of treatment guidelines for PALs. In the past 20 years, newer and less invasive treatment options have been developed...
August 2017: Chest
https://www.readbyqxmd.com/read/28230230/bronchoscopic-lung-volume-reduction-procedures-for-chronic-obstructive-pulmonary-disease
#11
REVIEW
Joseph Em van Agteren, Khin Hnin, Dion Grosser, Kristin V Carson, Brian J Smith
BACKGROUND: In the recent years, a variety of bronchoscopic lung volume reduction (BLVR) procedures have emerged that may provide a treatment option to participants suffering from moderate to severe chronic obstructive pulmonary disease (COPD). OBJECTIVES: To assess the effects of BLVR on the short- and long-term health outcomes in participants with moderate to severe COPD and determine the effectiveness and cost-effectiveness of each individual technique. SEARCH METHODS: Studies were identified from the Cochrane Airways Group Specialised Register (CAGR) and by handsearching of respiratory journals and meeting abstracts...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28186686/combined-bone-marrow-derived-mesenchymal-stromal-cell-therapy-and-one-way-endobronchial-valve-placement-in-patients-with-pulmonary-emphysema-a-phase-i-clinical-trial
#12
Hugo Goulart de Oliveira, Fernanda Ferreira Cruz, Mariana Alves Antunes, Amarilio Vieira de Macedo Neto, Guilherme Augusto Oliveira, Fabio Munhoz Svartman, Tamara Borgonovo, Carmen Lucia Kuniyoshi Rebelatto, Daniel J Weiss, Paulo Roberto Slud Brofman, Marcelo Marcos Morales, José Roberto Lapa E Silva, Patricia Rieken Macedo Rocco
One-way endobronchial valves (EBV) insertion to reduce pulmonary air trapping has been used as therapy for chronic obstructive pulmonary disease (COPD) patients. However, local inflammation may result and can contribute to worsening of clinical status in these patients. We hypothesized that combined EBV insertion and intrabronchial administration of mesenchymal stromal cells (MSCs) would decrease the inflammatory process, thus mitigating EBV complications in severe COPD patients. This initial study sought to investigate the safety of this approach...
March 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/27992862/endobronchial-valves-for-endoscopic-lung-volume-reduction-best-practice-recommendations-from-expert-panel-on-endoscopic-lung-volume-reduction
#13
Dirk-Jan Slebos, Pallav L Shah, Felix J F Herth, Arschang Valipour
Endoscopic lung volume reduction (ELVR) is being adopted as a treatment option for carefully selected patients suffering from severe emphysema. ELVR with the one-way endobronchial Zephyr valves (EBV) has been demonstrated to improve pulmonary function, exercise capacity, and quality of life in patients with both heterogeneous and homogenous emphysema without collateral ventilation. In this "expert best practices" review, we will highlight the practical aspects of this therapy. Key selection criteria for ELVR are hyperinflation with a residual volume >175% of predicted, forced expiratory volume <50% of predicted, and a 6-min walking distance >100 m...
2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27974713/one-year-follow-up-after-endobronchial-valve-treatment-in-patients-with-emphysema-without-collateral-ventilation-treated-in-the-stelvio-trial
#14
Karin Klooster, Jorine E Hartman, Nick H T Ten Hacken, Dirk-Jan Slebos
BACKGROUND: One-way endobronchial valve (EBV) treatment has shown safety and efficacy at 6 months after treatment in patients with severe emphysema and confirmed absence of interlobar collateral ventilation. Longer follow-up in this subgroup is not available. OBJECTIVES: To investigate the efficacy and safety of EBV treatment of the STELVIO cohort at a 1-year follow-up. METHODS: Emphysema patients who have been treated with EBV in the STELVIO trial were invited for a voluntary 1-year follow-up visit...
2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27920518/significant-lung-volume-reduction-with-endobronchial-valves-in-a-patient-despite-the-presence-of-microcollaterals-masked-by-low-flow-chartis-phenotype
#15
Yan Yin, Gang Hou, Felix J Herth, Xiao-Bo Wang, Qiu-Yue Wang, Jian Kang
Satisfactory functional outcomes following bronchoscopic lung volume reduction (BLVR) using endobronchial valves (EBVs) depend on the absence of collateral ventilation (CV) between the target and adjunct lobes. The Chartis system has proven to be useful for determining whether CV is present or absent, but this system can also erroneously indicate the absence of CV, which can lead to BLVR failure. Here, we describe low-flow Chartis phenotype in the target lobe resulted in difficult judgment of existence of CV...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27814898/endobronchial-valve-therapy-for-a-refractory-air-leak-after-lung-transplantation-in-a-patient-with-multiple-connective-tissue-disorders
#16
John R Spratt, Eitan Podgaetz, Gabriel Loor, Sara J Shumway
No abstract text is available yet for this article.
January 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27806368/endobronchial-valves-for-emphysema-time-to-push-the-envelope
#17
Zaid Zoumot, Samuel V Kemp, Pallav L Shah
No abstract text is available yet for this article.
2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27806152/bronchoscopic-management-of-prolonged-air-leaks-with-endobronchial-valves-in-a-veteran-population
#18
Lorraine D Cornwell, Ramola Panchal, Faisal G Bakaeen, Shuab Omer, Ourania Preventza, Donald R Lazarus, Roberto F Casal
No abstract text is available yet for this article.
February 1, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/27797610/endobronchial-valves-as-a-treatment-for-emphysema-moving-out-of-the-shadow-of-lung-volume-reduction-surgery
#19
Nicholas S Hopkinson
No abstract text is available yet for this article.
November 1, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27776598/endobronchial-valve-treatment-of-destructive-multidrug-resistant-tuberculosis
#20
A Levin, S Sklyuev, I Felker, E Tceymach, D Krasnov
BACKGROUND: In accordance with the existing hypothesis, the application of an endobronchial valve (EbV) leads to selective curative atelectasis of the affected part of the lung, contributing to early closure of cavities. OBJECTIVE: To assess the effect of EbV treatment on the course of tuberculosis (TB). METHODS: We compared the efficacy of EbV treatment and complex second-line treatment in treating patients with destructive pulmonary multidrug-resistant TB (MDR-TB)...
November 2016: International Journal of Tuberculosis and Lung Disease
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