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https://www.readbyqxmd.com/read/28545279/-impact-of-gender-and-age-on-in-hospital-major-adverse-cardiovascular-and-cerebrovascular-events-of-patients-with-acute-st-segment-elevation-myocardial-infarction
#1
Q N Shen, D X Wang, H B Zhai, Z C Dong, J Liu, B Zhang
Objective: To investigate the impact of gender and age on in-hospital major adverse cardiovascular and cerebrovascular events of patients with acute ST-segment elevation myocardial infarction (STEMI). Methods: This is a retrospective single-center study. A total of consecutive 1 102 patients with acute STEMI admitted to our hospital from January 2001 to December 2010 were recruited and clinical data were analyzed. The primary end point was in-hospital death due to any cause, and the secondary end point was in-hospital composite end point including death, re-infarction and stroke...
April 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28545269/-risk-factors-of-endometriosis-associated-ovarian-carcinoma-in-women-aged-45-years-and-older
#2
Z X He, S Wang, Z F Li, L Zhu, J H Leng, J H Lang
Obiective: To explore the risk factors of endometriosis-associated ovarian cancer (EAOC) in women with ovarian endometriosis aged 45 years and older in China. Methods: The medical records of total 1 038 women aged 45 years and older with a surgicopathological diagnosis of ovarian endometriosis treated at Peking Union Medical College Hospital from December 1994 to December 2014 were reviewed. Histology evaluation determined ovarian endometriosis with (n=30) or without (n=1 008) ovarian cancer. Results: (1) There were 30 (2...
May 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28545258/marker-assisted-molecular-profiling-deletion-mutant-analysis-and-rna-seq-reveal-a-disease-resistance-cluster-associated-with-uromyces-appendiculatus-infection-in-common-bean-phaseolus-vulgaris-l
#3
Antonette R Todd, Nicole Donofrio, Venkateswara R Sripathi, Phillip E McClean, Rian K Lee, Marcial Pastor-Corrales, Venu Kal Kalavacharla
Common bean (Phaseolus vulgaris L.) is an important legume, useful for its high protein and dietary fiber. The fungal pathogen Uromyces appendiculatus (Pers.) Unger can cause major loss in susceptible varieties of the common bean. The Ur-3 locus provides race specific resistance to virulent strains or races of the bean rust pathogen along with Crg, (Complements resistance gene), which is required for Ur-3-mediated rust resistance. In this study, we inoculated two common bean genotypes (resistant "Sierra" and susceptible crg) with rust race 53 of U...
May 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28545247/how-does-psychosocial-behavior-contribute-to-cognitive-health-in-old-age
#4
Robert S Wilson, David A Bennett
With the aging of the U.S. population, the number of cognitively disabled persons is expected to substantially increase in coming decades, underscoring the urgent need for effective interventions. Here, we review the current evidence linking psychosocial factors to late-life cognitive loss and consider the study design needed to illuminate the biologic bases of the associations. We then examine an ongoing study that includes several of the key design elements, the Rush Memory and Aging Project. In this longitudinal clinical-pathological cohort study, indicators of personality, social connectedness, and psychological well-being were shown to predict late-life cognitive outcomes...
May 23, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28545246/increasing-the-use-of-urban-greenways-in-developing-countries-a-case-study-on-wutong-greenway-in-shenzhen-china
#5
Yiyong Chen, Weiying Gu, Tao Liu, Lei Yuan, Mali Zeng
Given the benefits of urban greenways on the health and well-being of urban populations, the increased use of urban greenways has garnered increasing attention. Studies on urban greenways, however, have been mostly conducted in Western countries, whereas there is limited knowledge on greenway use in urban areas in developing countries. To address this shortcoming, the present study selected Wutong Greenway in Shenzhen, China, as a case study and focused on the use pattern and factors that influence the frequency and duration of urban greenway use in developing countries...
May 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28545237/emotion-recognition-in-adolescents-with-down-syndrome-a-nonverbal-approach
#6
Régis Pochon, Claire Touchet, Laure Ibernon
Several studies have reported that persons with Down syndrome (DS) have difficulties recognizing emotions; however, there is insufficient research to prove that a deficit of emotional knowledge exists in DS. The aim of this study was to evaluate the recognition of emotional facial expressions without making use of emotional vocabulary, given the language problems known to be associated with this syndrome. The ability to recognize six emotions was assessed in 24 adolescents with DS. Their performance was compared to that of 24 typically developing children with the same nonverbal-developmental age, as assessed by Raven's Progressive Matrices...
May 23, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28545226/emergence-of-cd26-cancer-stem-cells-with-metastatic-properties-in-colorectal-carcinogenesis
#7
Alvin Ho-Kwan Cheung, Deepak Narayanan Iyer, Colin Siu-Chi Lam, Lui Ng, Sunny K M Wong, Hung-Sing Lee, Timothy Wan, Johnny Man, Ariel K M Chow, Ronnie T Poon, Roberta Pang, Wai-Lun Law
Colorectal cancer results from genetic aberrations which accumulate over a long period of time, with malignant and metastatic properties acquired at a relatively late stage. A subpopulation of CD26+ colorectal cancer stem cells are known to be implicated in metastasis. We quantified CD26+ cancer cells in 11 primary tumor samples by flow cytometry, and showed that tumors having confirmed or suspected metastases harbored a relatively high CD26+ level in these samples. We hypothesized that this subpopulation of cancer stem cells arises in the late stage of carcinogenesis from the bulk of tumor daughter cells which are CD26-...
May 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28545225/state-of-art-of-cancer-pharmacogenomics-in-latin-american-populations
#8
REVIEW
Andrés López-Cortés, Santiago Guerrero, María Ana Redal, Angel Tito Alvarado, Luis Abel Quiñones
Over the past decades, several studies have shown that tumor-related somatic and germline alterations predicts tumor prognosis, drug response and toxicity. Latin American populations present a vast geno-phenotypic diversity due to the great interethnic and interracial mixing. This genetic flow leads to the appearance of complex characteristics that allow individuals to adapt to endemic environments, such as high altitude or extreme tropical weather. These genetic changes, most of them subtle and unexplored, could establish a mutational profile to develop new pharmacogenomic therapies specific for Latin American populations...
May 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28545212/determination-of-phenolic-organohalogens-in-human-serum-from-a-belgian-population-and-assessment-of-parameters-affecting-the-human-contamination
#9
Patrice Dufour, Catherine Pirard, Corinne Charlier
Many in vitro or in vivo studies highlighted the potential deleterious effects of phenolic organohalogenated compounds (POHs) on the health, particularly on the thyroid system homeostasis, however few large scale human epidemiological studies have been carried out, especially in Europe. Further studies monitoring the human contamination by POHs, the sources of exposure and the influence of these compounds on thyroid health are still needed. Therefore we determined the concentrations of 16 POHs (pentachlorophenol (PCP), tetrabromobisphenol A (TBBPA), 4 bromophenols (BPs), 3 hydroxy-polybromodiphenylethers (OH-PBDEs) and 7 hydroxy-polychlorobiphenyls (OH-PCBs)) in serum from 274 people aged from 18 to 76years old living in Liege (Belgium) and the surrounding area...
May 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28545209/the-footprint-of-marginal-agriculture-in-the-mediterranean-mountain-landscape-an-analysis-of-the-central-spanish-pyrenees
#10
T Lasanta, E Nadal-Romero, M P Errea
Agriculture forms an essential part of the mountains of the Mediterranean. For centuries, large areas were cultivated to feed the local population, with highly marginal slopes being tilled at times of heavy demographic pressure, using the shifting agriculture system. A great deal of agricultural land was abandoned during the 20th century, giving rise to secondary succession processes that tend to eliminate the agricultural footprint. However, revegetation is a highly complex process leading to areas with dense, well-structured plant cover, and other open areas of scrubland...
May 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28545208/spatio-temporal-analysis-of-particulate-matter-intake-fractions-for-vehicular-emissions-hourly-variation-by-micro-environments-in-the-greater-toronto-and-hamilton-area-canada
#11
Weeberb J Requia, Matthew D Adams, Altaf Arain, Petros Koutrakis, Wan-Chen Lee, Mark Ferguson
Previous investigations have reported intake fraction (iF) for different environments, which include ambient concentrations (outdoor exposure) and microenvironments (indoor exposure). However, little is known about iF variations due to space-time factors, especially in microenvironments. In this paper, we performed a spatio-temporal analysis of particulate matter (PM2.5) intake fractions for vehicular emissions. Specifically, we investigated hourly variation (12:00am-11:00pm) by micro-environments (residences and workplaces) in the Greater Toronto and Hamilton Area (GTHA), Canada...
May 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28545204/ecomorphological-divergence-drives-differential-mercury-bioaccumulation-in-polymorphic-european-whitefish-coregonus-lavaretus-populations-of-subarctic-lakes
#12
Kimmo K Kahilainen, Stephen M Thomas, Elina K M Nystedt, Ossi Keva, Tommi Malinen, Brian Hayden
Resource polymorphism, whereby ancestral trophic generalists undergo divergence into multiple specialist morphs, is common in salmonid fish populations inhabiting subarctic lakes. However, the extent to which such resource specialization into the three principal lake habitats (littoral, profundal, and pelagic) affects patterns of contaminant bioaccumulation remains largely unexplored. We assessed total mercury concentrations (THg) of European whitefish (Coregonus lavaretus (L.)) and their invertebrate prey in relation to potential explanatory variables across 6 subarctic lakes, of which three are inhabited by polymorphic (comprised of four morphs) and three by monomorphic populations...
May 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28545200/descriptive-epidemiology-of-female-breast-cancer-in-delhi-india
#13
Nalliah Manoharan, Omana Nair, N K Shukla, Goura Kishor Rath
Background: Breast cancer is the most frequently diagnosed cancer in females worldwide. The Population Based Cancer Registry data of Delhi were here used to describe the epidemiology and trends in breast cancer incidence in Delhi. Methods: Crude rate, age-standardized incidence rates (ASR) and age-specific incidence rates were calculated using the data collected by Delhi PBCR for the year 2012. The time trend of breast cancer incidence was evaluated by joinpoint regression using the PBCR data from 1988-2012...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28545193/synthesis-characterization-and-cytotoxic-evaluation-of-graphene-oxide-nanosheets-in-vitro-liver-cancer-model
#14
Samah A Loutfy, Taher A Salaheldin, Marwa A Ramadan, Khaled Yehia Farroh, Zeinab F Abdallah, Tareq Youssef Abd Eloahed
Background: Graphene nanosheets have a broad spectrum of biomedical applications. Hepatocellular cancer (HCC) is a major health problem in the Egyptian population. Currently, treatment strategies are invasive and have several adverse side effects. Thus, other approaches are required for managing this aggressive type of cancer. Our objective here was to prepare and characterize graphene oxide nanosheets and evaluate cytotoxic effect at the molecular level in an in vitro human liver cancer cell model (HepG2)...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28545190/radiation-exposure-in-patients-with-inflammatory-bowel-disease-a-fourteen-year-review-at-a-tertiary-care-centre-in-malaysia
#15
Jeevinesh Naidu, Zhiqin Wong, Shanthi Palaniappan, Chai Soon Ngiu, Raja Affendi Raja Ali
Background and Aims: Patients with inflammatory bowel disease (IBD) are subjected to a large amount of ionizing radiation during the course of their illness. This may increase their risk of malignancy to a greater level than that due to the disease itself. In Caucasian patients with Crohn’s disease, this has been well documented and recommendations are in place to avoid high radiation imaging protocols. However, there are limited data available on radiation exposure in Asian IBD patients.We therefore sought to identify total radiation exposure and any differences between ethnically diverse ulcerative colitis (UC) and Crohn’s disease (CD) patients at our centre along with determining factors that may contribute to any variation...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28545182/breast-cancer-in-australian-indigenous-women-incidence-mortality-and-risk-factors
#16
Kriscia A Tapia, Gail Garvey, Mark Mc Entee, Mary Rickard, Patrick Brennan
The Indigenous people of Australia face significant health gaps compared with the general population, with lower life expectancies, higher rates of death, and chronic illness occurring more often than in non-indigenous Australians. Cancer is the second largest contributor to the burden of disease with breast cancer being the most common invasive cancer diagnosed for females. Despite a lower breast cancer incidence compared with non-indigenous women, fatalities occur at an elevated rate and breast cancers have an earlier age of onset...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28545155/rapid-diagnostic-tests-for-typhoid-and-paratyphoid-enteric-fever
#17
REVIEW
Lalith Wijedoru, Sue Mallett, Christopher M Parry
BACKGROUND: Differentiating both typhoid (Salmonella Typhi) and paratyphoid (Salmonella Paratyphi A) infection from other causes of fever in endemic areas is a diagnostic challenge. Although commercial point-of-care rapid diagnostic tests (RDTs) for enteric fever are available as alternatives to the current reference standard test of blood or bone marrow culture, or to the widely used Widal Test, their diagnostic accuracy is unclear. If accurate, they could potentially replace blood culture as the World Health Organization (WHO)-recommended main diagnostic test for enteric fever...
May 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28545149/persistence-of-lineage-iv-peste-des-petits-ruminants-virus-within-israel-since-1993-an-evolutionary-perspective
#18
Brian Clarke, Mana Mahapatra, Orly Friedgut, Velizar Bumbarov, Satya Parida
Peste-des-petits ruminants (PPR) is one of the most important infectious diseases of domesticated small ruminants. From the initial identification in 1942 in West Africa, PPR virus (PPRV) has spread throughout much of the developing world. PPRV is now considered endemic throughout Africa, with the notable exception of South Africa, the Middle-East and Israel, as well as South-, East-, and Central Asia. Despite this widespread dispersal, the evolution and transmission of PPRV in endemic populations is not well understood...
2017: PloS One
https://www.readbyqxmd.com/read/28545145/respiratory-response-to-temperature-of-three-populations-of-aurelia-aurita-polyps-in-northern-europe
#19
Danja P Höhn, Cathy H Lucas, Sven Thatje
The benthic life stage (polyp or scyphistoma) of the bloom-forming jellyfish, Aurelia aurita (Linnaeus, 1759), also known as the moon jellyfish, contributes to the seasonal occurrence and abundance of medusa blooms via asexual reproduction. A. aurita is widely distributed in coastal areas in northern Europe, and one of the most studied jellyfish species. While the physiology of the visible medusa is largely understood, understanding of the physiology of the perennial benthic life-stage is scarce. To measure the physiological tolerance of A...
2017: PloS One
https://www.readbyqxmd.com/read/28545132/proteomics-investigation-of-oscc-specific-salivary-biomarkers-in-a-hungarian-population-highlights-the-importance-of-identification-of-population-tailored-biomarkers
#20
Éva Csősz, Péter Lábiscsák, Gergő Kalló, Bernadett Márkus, Miklós Emri, Adrienn Szabó, Ildikó Tar, József Tőzsér, Csongor Kiss, Ildikó Márton
Oral squamous cell carcinoma (OSCC) accounting for about 90% of malignant oral lesions is the 6th most common malignancy worldwide. Diagnostic delay may contribute to dismal survival rate therefore, there is a need for developing specific and sensitive biomarkers to improve early detection. Hungarian population occupies the top places of statistics regarding OSCC incidence and mortality figures therefore, we aimed at finding potential salivary protein biomarkers suitable for the Hungarian population. In this study we investigated 14 proteins which were previously reported as significantly elevated in saliva of patients with OSCC...
2017: PloS One
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