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chromium and nickel toxicity

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https://www.readbyqxmd.com/read/29705899/interplay-between-elemental-imbalance-related-pi3k-akt-mtor-regulated-apoptosis-and-autophagy-in-arsenic-iii-induced-jejunum-toxicity-of-chicken
#1
Yu Wang, Hongjing Zhao, Yizhi Shao, Juanjuan Liu, Jinglun Li, Mingwei Xing
Arsenic trioxide (As2 O3 ), the most toxic form of arsenic found in foodstuffs, is considered a carcinogen for human and animal. But many of the events that occur during its passage through the gastrointestinal tract are uncharted in birds. This study assesses the toxic effect on the jejunum of chicken which subchronically exposed to diets that contain As2 O3 (0, 0.625, 1.25, 2.5 mg/kg body weight) for 90 days. Electron microscopy, TdT-mediated dUTP nick-end labeling (TUNEL), qPCR, and Western blot were performed...
April 28, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29700420/exposure-to-toxic-metals-triggers-unique-responses-from-the-rat-gut-microbiota
#2
Joshua B Richardson, Blair C R Dancy, Cassandra L Horton, Young S Lee, Michael S Madejczyk, Zhenjiang Zech Xu, Gail Ackermann, Gregory Humphrey, Gustavo Palacios, Rob Knight, John A Lewis
Our understanding of the interaction between the gut microbiota and host health has recently improved dramatically. However, the effects of toxic metal exposure on the gut microbiota remain poorly characterized. As this microbiota creates a critical interface between the external environment and the host's cells, it may play an important role in host outcomes during exposure. We therefore used 16S ribosomal RNA (rRNA) gene sequencing to track changes in the gut microbiota composition of rats exposed to heavy metals...
April 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29679700/toxicity-of-porcelain-fused-to-metal-substrate-to-zebrafish-danio-rerio-embryos-and-larvae
#3
Libo Zhao, Jing Si, Yuan Wei, Sirui Li, Yanjiao Jiang, Rong Zhou, Bin Liu, Hong Zhang
AIMS: Porcelain-fused-to-metal (PFM) crowns are a standard restoration technique in dentistry, but toxicity of PFM in vivo has not been systematically evaluated. The present study evaluated the effects of various metal alloy shells of PFM crowns on the development of zebrafish embryos and larvae in order to determine the safety of these materials. MAIN METHODS: Gold palladium (Au-Pd), silver palladium (Ag-Pd), Nickel chromium (Ni-Cr), cobalt chromium (Co-Cr), titanium (Ti) alloy porcelain crowns were immersed in artificial saliva for 1, 4, and 7 weeks, and the leach solution was collected and used to treat zebrafish embryos at 4-144 h PFM...
April 18, 2018: Life Sciences
https://www.readbyqxmd.com/read/29679608/detection-and-quantitative-determination-of-heavy-metals-in-electronic-cigarette-refill-liquids-using-total-reflection-x-ray-fluorescence-spectrometry
#4
Eleni Kamilari, Konstantinos Farsalinos, Konstantinos Poulas, Christos G Kontoyannis, Malvina G Orkoula
Electronic cigarettes are considered healthier alternatives to conventional cigarettes containing tobacco. They produce vapor through heating of the refill liquids (e-liquids) which consist of propylene glycol, vegetable glycerin, nicotine (in various concentrations), water and flavoring agents. Heavy metals may enter the refill liquid during the production, posing a risk for consumer's health due to their toxicity. The objective of the present study was the development of a methodology for the detection and quantitative analysis of cadmium (Cd), lead (Pb), nickel (Ni), copper (Cu), arsenic (As) and chromium (Cr), employing Total Reflection X-Ray Fluorescence Spectroscopy (TXRF) as an alternative technique to ICP-MS or ICP-OES commonly used for this type of analysis...
April 18, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29676648/global-tobacco-use-old-and-new-products
#5
Ana Navas-Acien
Tobacco use and exposure to tobacco smoke remain major but avoidable causes of premature mortality and disease worldwide. Although the age-standardized prevalence of daily smoking has declined for both men and women in many countries, the number of smokers continues to increase because of global population growth. Although cigarettes are the most commonly used tobacco product, the tobacco epidemic has become tremendously complex with the emergence and popularity of alternative products such as waterpipes and electronic cigarettes (also known as e-cigarettes)...
April 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29666936/assessment-of-toxic-impact-of-metals-on-proline-antioxidant-enzymes-and-biological-characteristics-of-pseudomonas-aeruginosa-inoculated-cicer-arietinum-grown-in-chromium-and-nickel-stressed-sandy-clay-loam-soils
#6
Saima Saif, Mohammad Saghir Khan
Considering the heavy metal risk to soil microbiota and agro-ecosystems, the study was designed to determine metal toxicity to bacteria and to find metal tolerant bacteria carrying multifarious plant growth promoting activities and to assess their impact on chickpea cultivated in stressed soils. Metal tolerant strain SFP1 recognized as Pseudomonas aeruginosa employing 16S rRNA gene sequence determination showed maximum tolerance to Cr (400 μg/ml) and Ni (800 μg/ml) and produced variable amounts of indole acetic acid, HCN, NH3 , and ACC deaminase and could solubilize insoluble phosphates even under Cr (VI) and Ni stress...
April 17, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29627419/health-risk-assessment-of-heavy-metals-in-freshwater-fish-in-the-central-and-eastern-north-china
#7
Wenjue Zhong, Yanfeng Zhang, Zihao Wu, Rongyan Yang, Xinyue Chen, Jing Yang, Lingyan Zhu
The distribution and potential health risks of eight heavy metals (Copper (Cu), Chromium (Cr), Zinc (Zn), Lead (Pb), Arsenic (As), Cadmium (Cd), Manganese (Mn), Nickel (Ni)) in 16 freshwater systems from central and eastern North China, were investigated. The fish were divided as wild fish, which grew naturally without artificially feeding, and farmed fish. The total concentrations of the eight heavy metals ranged from 82.9 to 226 μg/L in the surface water samples and 3.32-27.6 mg/kg dw in the fish samples...
April 5, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29594881/potential-application-of-pre-treated-municipal-solid-waste-incineration-fly-ash-as-cement-supplement
#8
Yahaya Yakubu, Jun Zhou, Zhu Shu, Yi Zhang, Wenbin Wang, Yassin Mbululo
Pre-treatment process carried out on raw municipal solid waste incineration (MSWI) fly ash (FA) sample that did not comply initially with the USEPA method 1311 toxicity characteristic leaching procedure (TCLP) regulatory limits of 2011 reduced its chloride and heavy metal content appreciably, thereby making it compliant with the aforementioned regulatory requirement. More than 98% of each heavy metal was successfully removed. The process was excellent in removing cadmium (Cd) (99.99%) and very good at removing the rest...
March 29, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29593817/identification-of-toxic-metals-in-human-embryonic-tissues
#9
Piotr Rzymski, Przemysław Niedzielski, Barbara Poniedziałek, Katarzyna Tomczyk, Paweł Rzymski
Introduction: The cause of a significant number of miscarriages remains unexplained. There is a need to identify the potential role of environmental, dietary and lifestyle factors in the risk of pregnancy loss. The present study was the first to investigate the content of miscarried embryonic material with respect to eight metals (aluminium, cadmium, chromium, copper, manganese, nickel, lead and zinc). Material and methods: Embryonic tissue samples ( n = 20) were obtained from women undergoing misoprostol-induced removal of the embryo between the 6th and 9th week of gestation...
March 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29574360/acidic-leaching-of-potentially-toxic-metals-cadmium-cobalt-chromium-copper-nickel-lead-and-zinc-from-two-zn-smelting-slag-materials-incubated-in-an-acidic-soil
#10
Taoze Liu, Feili Li, Zhisheng Jin, Yuangen Yang
A column leaching study, coupled with acid deposition simulation, was conducted to investigate the leaching of potentially toxic metals (PTM) from zinc smelting slag materials (SSM) after being incubated in an acid Alfisol for 120 days at room temperature. Two SSMs (SSM-A: acidic, 10 yrs exposure with moderate high PTM concentrations versus SSM-B: alkaline, 2 yrs exposure with extremely high PTM concentrations), were used for the incubation at 0.5, 1, 2.5, 5 wt% amendment ratios in triplicate. Five leaching events were conducted at day 1, 3, 7, 14, and 28, and the leaching of PTMs mainly occurred in the first three leaching events, with the highest PTM concentrations in leachate measured from 5 wt% SSM amendments...
March 22, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29550572/interactions-between-chromium-iii-and-iron-iii-molybdenum-iii-or-nickel-ii-cytotoxicity-genotoxicity-and-mutagenicity-studies
#11
Sylwia Terpilowska, Andrzej Krzysztof Siwicki
The aim of this study was to examine the effect of chromium(III) and iron(III) and molybdenum(III) and nickel(II) and their combinations on cyto-, genotoxicity and mutagenicity in BALB/3T3 and HepG2 cells. The results obtained from cytotoxicity assays indicate that there are differences between BALB/3T3 and HepG2 cell lines in their sensitivity to chromium chloride, iron chloride, molybdenum trioxide and nickel chloride. The statistically significant increase of DNA damage of all used microelements in both cell lines was observed...
March 10, 2018: Chemosphere
https://www.readbyqxmd.com/read/29525864/development-of-an-in-vitro-toxicological-test-system-based-on-zebrafish-danio-rerio-sperm-analysis
#12
Tímea Kollár, Eszter Kása, Árpád Ferincz, Béla Urbányi, Zsolt Csenki-Bakos, Ákos Horváth
The effect of seven heavy metals on the motility parameter of zebrafish sperm was tested in order to develop an in vitro toxicological test system as an alternative to live animal testing. In vitro test systems are currently preferred in ecotoxicology due to their practical and ethical advantages and fish sperm can be a suitable model. A number of studies had been carried out previously on this topic, but the described methods had not been standardized in numerous aspects (donor species, measured endpoint, etc...
March 10, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29520558/the-role-of-heavy-metals-and-polychlorinated-biphenyls-pcbs-in-the-oncogenesis-of-head-and-neck-tumors-and-thyroid-diseases-a-pilot-study
#13
V Petrosino, G Motta, G Tenore, M Coletta, A Guariglia, D Testa
Previous literature has highlighted the mechanisms of molecular toxicity induced by substances such as arsenic, cadmium, chromium, nickel, lead, barium and PCBs. The research was carried out on 20 volunteers, all the patients gave their consent to the research: the aim of the study was to evaluate the presence of metals and PCBs in these different matrices (blood and hair), correlating the biochemical data to pathological conditions present, and also to the area in which patients resided. Various quantitative determinations were carried out on samples of blood and hair for 14 heavy metals and on blood samples for 12 PCBs...
April 2018: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/29494971/occurrence-and-risk-assessment-of-potentially-toxic-elements-and-typical-organic-pollutants-in-contaminated-rural-soils
#14
Yongfeng Xu, Shixiang Dai, Ke Meng, Yuting Wang, Wenjie Ren, Ling Zhao, Peter Christie, Ying Teng
The residual levels and risk assessment of several potentially toxic elements (PTEs), phthalate esters (PAEs) and polycyclic aromatic hydrocarbons (PAHs) in rural soils near different types of pollution sources in Tianjin, China, were studied. The soils were found to be polluted to different extents with PTEs, PAEs and PAHs from different pollution sources. The soil concentrations of chromium (Cr), nickel (Ni), di-n-butyl phthalate (DnBP), acenaphthylene (Any) and acenaphthene (Ane) were higher than their corresponding regulatory reference limits...
July 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29459162/enrichment-spatial-distribution-of-potential-ecological-and-human-health-risk-assessment-via-toxic-metals-in-soil-and-surface-water-ingestion-in-the-vicinity-of-sewakht-mines-district-chitral-northern-pakistan
#15
Inayat Ur Rehman, Muhammad Ishaq, Liaqat Ali, Sardar Khan, Imtiaz Ahmad, Imran Ud Din, Hameed Ullah
This study focuses on enrichment, spatial distribution, potential ecological risk index (PERI) and human health risk of various toxic metals taken via soil and surface water in the vicinity of Sewakht mines, Pakistan. The samples of soils (n = 54) of different fields and surface water (n = 38) were analyzed for toxic metals including cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), lead (Pb), nickel (Ni), zinc (Zn) and molybdenum (Mo). Soil pollution level was evaluated using pollution indices including geo-accumulation index (Igeo), contamination factor (CF), degree of contamination (CD), enrichment factor (EF) and PERI...
June 15, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29423230/review-of-carcinogenicity-of-hexavalent-chrome-and-proposal-of-revising-approval-standards-for-an-occupational-cancers-in-korea
#16
Jungwon Kim, Sangyun Seo, Yangho Kim, Dae Hwan Kim
Background: The objective of this study is to suggest revised recognition standards for occupational disease due to chromium (VI) by reflecting recent domestic and international research works and considering domestic exposure status with respect to target organs, exposure period, and cumulative exposure dose in relation to the chromium (VI)-induced occupational disease compensation. Methods: In this study, the reports published by major international institutions such as World Health Organization (WHO) International Agency for Research on Cancer (IARC) (2012), Occupational Safety and Health Administration (OSHA) (2006), National Institute for Occupational Safety and Health (NIOSH) (2013), American Conference of Governmental Industrial Hygienists (ACGIH) (2004), National Toxicology Program (NTP) (2014), and Agency for Toxic Substances and Disease Registry (ASTDR) (2012) were reviewed and the recent research works searched by PubMed were summarized...
2018: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29413098/status-and-interrelationship-of-toenail-elements-in-pacific-children
#17
Shamshad Karatela, Neil I Ward, Irene Suilan Zeng, Janis Paterson
OBJECTIVE: Elemental deficiencies or in excess effects growth and development. Pacific population are at a disadvantage due to food insecurity as compared to New Zealand European households. This study aims to evaluate the status and interrelationship of elements (essential, non-essential and toxic) in nine-year-old Pacific children who were part of the Pacific Island Families Study living in New Zealand. MATERIALS AND METHODS: This observational study included 278 eligible nine-year-old children...
March 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29321978/toxicity-of-formulants-and-heavy-metals-in-glyphosate-based-herbicides-and-other-pesticides
#18
N Defarge, J Spiroux de Vendômois, G E Séralini
The major pesticides of the world are glyphosate-based herbicides (GBH), and their toxicity is highly debated. To understand their mode of action, the comparative herbicidal and toxicological effects of glyphosate (G) alone and 14 of its formulations were studied in this work, as a model for pesticides. GBH are mixtures of water, with commonly 36-48% G claimed as the active principle. As with other pesticides, 10-20% of GBH consist of chemical formulants. We previously identified these by mass spectrometry and found them to be mainly families of petroleum-based oxidized molecules, such as POEA, and other contaminants...
2018: Toxicology Reports
https://www.readbyqxmd.com/read/29320235/a-limited-survey-of-metal-content-in-blue-jack-mackerel-trachurus-picturatus-obtained-from-markets-in-the-canary-islands
#19
Carmen Rubio, Laura Acosta, Gara Luis-González, Dailos González-Weller, Consuelo Revert, Arturo Hardisson, Ángel Gutiérrez
The levels of 20 metals (aluminum, boron, barium, calcium, cadmium, cobalt, chromium, copper, iron, potassium, lithium, magnesium, manganese, molybdenum, sodium, nickel, lead, strontium, vanadium, and zinc) were analyzed in muscle and liver tissue of Trachurus picturatus marketed in the Canary Islands (Spain) by using inductively coupled plasma optical emission spectrometry. In the liver samples, the mean concentrations in milligrams per kilogram wet weight (wt) of Al (14.7), B (0.99), Ba (1.64), Ca (314), Cd (2...
February 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29288979/in-vitro-genotoxic-effect-of-secondary-minerals-crystallized-in-rocks-from-coal-mine-drainage
#20
Adriane Perachi Nordin, Juliana da Silva, Claudia Telles de Souza, Liana A B Niekraszewicz, Johnny Ferraz Dias, Kátia da Boit, Marcos L S Oliveira, Ivana Grivicich, Ana Letícia Hilario Garcia, Luis Felipe Silva Oliveira, Fernanda Rabaioli da Silva
Coal processing generates a large volume of waste that can damage human health and the environment. Often these wastes produce acid drainage in which several minerals are crystallized (evaporites). This study aimed to identify secondary minerals, as well as the genotoxic potential of these materials. The samples were collected at two sites along the Rocinha River in Santa Catarina state (Brazil): (1) directly from the source of the acid drainage (evaporite 1), and (2) on the river bank (evaporite 2). The samples were characterized by X-ray diffraction and by particle-induced X-ray emission techniques...
March 15, 2018: Journal of Hazardous Materials
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