Nathalie Rohmann, Paula Stürmer, Corinna Geisler, Kristina Schlicht, Carina Knappe, Katharina Hartmann, Kathrin Türk, Tim Hollstein, Alexia Beckmann, Anna K Seoudy, Ulla Becker, Perdita Wietzke-Braun, Ute Settgast, Florian Tran, Philip Rosenstiel, Jan H Beckmann, Witigo von Schönfels, Stephan Seifert, Jan Heyckendorf, Andre Franke, Stefan Schreiber, Dominik M Schulte, Matthias Laudes
INTRODUCTION: Clara cell 16-kDa protein (CC16) is an anti-inflammatory, immunomodulatory secreted pulmonary protein with reduced serum concentrations in obesity according to recent data. OBJECTIVE: Studies focused solely on bodyweight, which does not properly reflect obesity-associated implications of the metabolic and reno-cardio-vascular system. The purpose of this study was therefore to examine CC16 in a broad physiological context considering cardio-metabolic comorbidities of primary pulmonary diseases...
June 16, 2023: Journal of Advanced Research