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Menopause AND weight loss

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https://www.readbyqxmd.com/read/28913660/weight-gain-in-hormone-receptor-positive-hr-early-stage-breast-cancer-is-it-menopausal-status-or-something-else
#1
Kirsten A Nyrop, Allison M Deal, Jordan T Lee, Hyman B Muss, Seul Ki Choi, Amy Wheless, Lisa A Carey, Shlomit S Shachar
PURPOSE: This study investigates weight trajectories in pre- versus postmenopausal breast cancer (BC) survivors diagnosed with hormone receptor-positive tumors, with a specific focus on discerning menopausal status and type of endocrine treatment (ET) as risk factors for weight gain during ET. METHODS: We conducted a retrospective review of electronic medical records. Descriptive statistics and Chi-squared and t tests were used to compare pre- and postmenopausal women...
September 14, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28903371/sociodemographic-and-economic-factors-are-associated-with-weight-gain-between-before-and-after-cancer-diagnosis-results-from-the-prospective-population-based-nutrinet-sant%C3%A3-cohort
#2
Philippine Fassier, Laurent Zelek, Patrick Bachmann, Marina Touillaud, Nathalie Druesne-Pecollo, Valentin Partula, Serge Hercberg, Pilar Galan, Patrice Cohen, Hélène Hoarau, Paule Latino-Martel, Bernard Srour, Rebeca Gonzalez, Mélanie Deschasaux, Mathilde Touvier
PURPOSE: While many cancer patients are affected by weight loss, others tend to gain weight, which may impact prognosis and risk of recurrence and of second cancer. The aim of this prospective study was to investigate weight variation between before and after cancer diagnosis and socio-demographic, economic, lifestyle and clinical factors associated with moderate-to-severe weight gain. METHODS: 1051 incident cases of first primary cancer were diagnosed in the NutriNet-Santé cohort between 2009 and 2015...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28899509/a-standardized-humulus-lupulus-l-ethanol-extract-partially-prevents-ovariectomy-induced-bone-loss-in-the-rat-without-induction-of-adverse-effects-in-the-uterus
#3
Annekathrin M Keiler, Janina Helle, Manuela I Bader, Tino Ehrhardt, Kristin Nestler, Georg Kretzschmar, Ricardo Bernhardt, Günter Vollmer, Dejan Nikolić, Judy L Bolton, Guido F Pauli, Shao-Nong Chen, Birgit M Dietz, Richard B van Breemen, Oliver Zierau
BACKGROUND: Hops (Humulus lupulus (L.)) dietary supplements are of interest as herbal remedies to alleviate menopausal symptoms, such as hot flushes, depression and anxiety. So far, the evidence regarding estrogenic and related properties of hops preparations has been considered insufficient for a market authorization for menopausal indications. PURPOSE: The study aims to investigate a chemically standardized hops extract regarding its safety in the uterus, as wells as its efficacy to prevent bone loss in the ovariectomized rat model...
October 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28791737/bone-marrow-fat-changes-after-gastric-bypass-surgery-are-associated-with-loss-of-bone-mass
#4
Tiffany Y Kim, Ann V Schwartz, Xiaojuan Li, Kaipin Xu, Dennis M Black, Dimitry M Petrenko, Lygia Stewart, Stanley J Rogers, Andrew M Posselt, Jonathan T Carter, Dolores M Shoback, Anne L Schafer
Bone marrow fat is a unique fat depot that may regulate bone metabolism. Marrow fat is increased in states of low bone mass, severe underweight, and diabetes. However, longitudinal effects of weight loss and improved glucose homeostasis on marrow fat are unclear, as is the relationship between marrow fat and bone mineral density (BMD) changes. We hypothesized that after Roux-en-Y gastric bypass (RYGB) surgery, marrow fat changes are associated with BMD loss. We enrolled 30 obese women, stratified by diabetes status...
August 9, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28734829/feasibility-of-prophylactic-salpingectomy-during-vaginal%C3%A2-hysterectomy
#5
Danielle D Antosh, Rachel High, Heidi W Brown, Sallie S Oliphant, Husam Abed, Nisha Philip, Cara L Grimes
BACKGROUND: The American Congress of Obstetricians and Gynecologists recommends that "the surgeon and patient discuss the potential benefits of the removal of the fallopian tubes during a hysterectomy in women at population risk of ovarian cancer who are not having an oophorectomy," resulting in an increasing rate of salpingectomy at the time of hysterectomy. Rates of salpingectomy are highest for laparoscopic and lowest for vaginal hysterectomy. OBJECTIVE: The primary objective of this study was to determine the feasibility of bilateral salpingectomy at the time of vaginal hysterectomy...
July 20, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28651370/changes-in-visceral-adiposity-subcutaneous-adiposity-and-sex-hormones-in-the-diabetes-prevention-program
#6
Catherine Kim, Dana Dabelea, Rita R Kalyani, Costas A Christophi, George A Bray, Xavier Pi-Sunyer, Christine H Darwin, Swaytha Yalamanchi, Elizabeth Barrett-Connor, Sherita Hill Golden, Edward J Boyko
Context: The degree to which changes in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) relate to corresponding changes in plasma sex steroids is not known. Objective: We examined whether changes in VAT and SAT areas assessed by computed tomography were associated with changes in sex hormones [dehydroepiandrosterone sulfate (DHEAS), testosterone, estradiol, estrone, and sex hormone binding globulin (SHBG)] among Diabetes Prevention Program participants...
September 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28634732/engineering-poly-lactic-co-glycolic-acid-plga-micro-and-nano-carriers-for-controlled-delivery-of-17%C3%AE-estradiol
#7
Alesia V Prakapenka, Heather A Bimonte-Nelson, Rachael W Sirianni
With menopause, circulating levels of 17β-estradiol (E2) markedly decrease. E2-based hormone therapy is prescribed to alleviate symptoms associated with menopause. E2 is also recognized for its beneficial effects in the central nervous system (CNS), such as enhanced cognitive function following abrupt hormonal loss associated with ovariectomy. For women with an intact uterus, an opposing progestogen component is required to decrease the risk of developing endometrial hyperplasia. While adding an opposing progestogen attenuates these detrimental effects on the uterus, it can attenuate the beneficial effects of E2 in the CNS...
July 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28620500/lugol-s-solution-induced-painless-thyroiditis
#8
Ji Wei Yang, Jacques How
Lugol's solution is usually employed for a limited period for thyroidectomy preparation in patients with Graves' disease and for the control of severe thyrotoxicosis and thyroid storm. We describe a rare case of Lugol's solution-induced painless thyroiditis. In November 2014, a 59-year-old woman was prescribed Lugol's solution four drops per day for the alleviation of menopausal symptoms. She was referred to our clinic in June 2015 for fatigue, hair loss, and a 20-lb weight loss without thyroid pain or discomfort...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28609591/obesity-and-weight-management-at-menopause
#9
Joseph Proietto
BACKGROUND: Many women report gaining weight as they transition through menopause. For most, the weight gain is modest and can be reduced with a conscious effort to limit energy intake and increase energy expenditure. However, many women who are already overweight and obese will gain more weight as they approach menopause. OBJECTIVE: The aims of this paper are to explain the reasons for menopausal weight gain and to detail a method for achieving and sustaining a substantial weight loss...
June 2017: Australian Family Physician
https://www.readbyqxmd.com/read/28600800/women-weight-poverty-and-menopause-understanding-health-practices-in-a-context-of-chronic-disease-prevention
#10
Mélisa Audet, Alex Dumas, Rachelle Binette, Isabelle J Dionne
Socioeconomic inequalities in health persist despite major investments in illness prevention campaigns and universal healthcare systems. In this context, the increased risks of chronic diseases of specific sub-groups of vulnerable populations should be further investigated. The objective of this qualitative study is to examine the interaction between socioeconomic status (SES) and body weight in order to understand underprivileged women's increased vulnerability to chronic diseases after menopause. By drawing specifically on Pierre Bourdieu's sociocultural theory of practice, 20 semi-structured interviews were conducted from May to December of 2013 to investigate the health practices of clinically overweight, postmenopausal women living an underprivileged life in Canada...
June 10, 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28545031/sociodemographic-and-economic-factors-are-associated-with-weight-gain-between-before-and-after-cancer-diagnosis-results-from-the-prospective-population-based-nutrinet-sant%C3%A3-cohort
#11
Philippine Fassier, Laurent Zelek, Patrick Bachmann, Marina Touillaud, Nathalie Druesne-Pecollo, Valentin Partula, Serge Hercberg, Pilar Galan, Patrice Cohen, Hélène Hoarau, Paule Latino-Martel, Bernard Srour, Rebeca Gonzalez, Mélanie Deschasaux, Mathilde Touvier
PURPOSE: While many cancer patients are affected by weight loss, others tend to gain weight, which may impact prognosis and risk of recurrence and of second cancer. The aim of this prospective study was to investigate weight variation between before and after cancer diagnosis and socio-demographic, economic, lifestyle and clinical factors associated with moderate-to-severe weight gain. METHODS: 1051 incident cases of first primary cancer were diagnosed in the NutriNet-Santé cohort between 2009 and 2015...
May 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28533263/prior-weight-loss-exacerbates-the-biological-drive-to-gain-weight-after-the-loss-of-ovarian-function
#12
Vanessa D Sherk, Matthew R Jackman, Erin D Giles, Janine A Higgins, Rebecca M Foright, David M Presby, Ginger C Johnson, Julie A Houck, Jordan L Houser, Robera Oljira, Paul S MacLean
Both the history of obesity and weight loss may change how menopause affects metabolic health. The purpose was to determine whether obesity and/or weight loss status alters energy balance (EB) and subsequent weight gain after the loss of ovarian function. Female lean and obese Wistar rats were randomized to 15% weight loss (WL) or ad libitum fed controls (CON). After the weight loss period, WL rats were kept in EB at the reduced weight for 8 weeks prior to ovariectomy (OVX). After OVX, all rats were allowed to eat ad libitum until weight plateaued...
May 2017: Physiological Reports
https://www.readbyqxmd.com/read/28529739/long-term-supplementation-with-young-coconut-juice-does-not-prevent-bone-loss-but-rather-alleviates-body-weight-gain-in-ovariectomized-rats
#13
Hiroshi Matsushita, Akira Minami, Hiroaki Kanazawa, Takashi Suzuki, Sanan Subhadhirasakul, Kazushi Watanabe, Akihiko Wakatsuki
Young coconut (Cocos nucifera Linn.) juice (YCJ) has traditionally been consumed to alleviate symptoms associated with the menopause. Recently, the authors demonstrated that short-term (6-week) YCJ supplementation to ovariectomized rats resulted in increased bone mass and bone formation parameter, suggesting that YCJ consumption has a positive effect on bone metabolism and may represent an intervention to help slow the bone loss during menopause transition. The present study sought to determine how long-term (12-week) YCJ supplementation affects bone metabolism in ovariectomized rats, to investigate whether such supplementation may be helpful to in osteoporosis treatment...
May 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28528727/sexual-inactivity-in-partnered-female-cancer-survivors
#14
Jennifer L Marino, Christobel M Saunders, Martha Hickey
OBJECTIVE: To measure sexual activity in a clinic population of partnered female cancer survivors, and to better understand reasons for sexual inactivity in this population. MATERIALS AND METHODS: Partnered peri- or post-menopausal cancer survivors seen at a specialty clinic for menopause symptoms after cancer completed Fallowfield's Sexual Activity Questionnaire, quality of life measures (the Functional Assessment of Cancer Therapy General, Breast Cancer, and Endocrine Symptom Scales), and the Greene Climacteric Scale...
May 9, 2017: Maturitas
https://www.readbyqxmd.com/read/28464798/the-effects-of-low-repetition-and-light-load-power-training-on-bone-mineral-density-in-postmenopausal-women-with-sarcopenia-a-pilot-study
#15
Kanako Hamaguchi, Toshiyuki Kurihara, Masahiro Fujimoto, Motoyuki Iemitsu, Koji Sato, Takafumi Hamaoka, Kiyoshi Sanada
BACKGROUND: Age-related reduction in bone mineral density (BMD) is generally accelerated in women after menopause, and could be even more pronounced in individuals with sarcopenia. Light-load power training with a low number of repetitions would increase BMD, significantly reducing bone loss in individuals at risk of osteoporosis. This study investigated the effects of low-repetition, light-load power training on BMD in Japanese postmenopausal women with sarcopenia. METHODS: The training group (n = 7) followed a progressive power training protocol that increased the load with a weighted vest, for two sessions per week, over the course of 6 weeks...
May 2, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28426535/frailty-in-hiv-infected-people-a-new-risk-factor-for-bone-mineral-density-loss
#16
Sylvie Bregigeon, Anne Galinier, Olivia Zaegel-Faucher, Carla E Cano, Véronique Obry, Hélène Laroche, Sophie Trijau, Armelle Saout, Isabelle Poizot-Martin
OBJECTIVE: The study aims to assess the association between bone mineral density (BMD) and frailty in a cohort of HIV-infected patients. DESIGN: A cross-sectional study in an HIV outpatient unit where nearly 1000 patients are monitored. METHODS: Study participants undergoing bone densitometry were proposed an evaluation of frailty using criteria of the Cardiovascular Health Study (CHS) and the Study of Osteoporotic Fractures (SOF). Frailty markers were weight-loss, self-reported exhaustion, physical activity, grip strength, chair stands, and slow gait...
July 17, 2017: AIDS
https://www.readbyqxmd.com/read/28413432/resveratrol-regulates-body-weight-in-healthy-and-ovariectomized-rats
#17
Rupali Sharma, Neel Kamal Sharma, M Thungapathra
OBJECTIVE: The elevated body weight in post-menopausal state attributes to the reduced estrogen levels which is alleviated by resveratrol (RES) but its role in control rats is not well understood. The main objective of the study was to explore the effects of RES on the body weight of ovariectomized (OVX) female rats with controls and to relate their biochemical parameters. METHODS: Female Wistar rats weighing 200-300 g underwent bilateral ovariectomy (OVX) and were fed soya free diet (n = 8 rats per group)...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28388998/menopause-and-exercise-intolerance
#18
REVIEW
Ann R Lurati
Central adiposity and weight gain are common among postmenopausal women. Because of the metabolic changes that many postmenopausal women experience, there can be a decrease in exercise tolerance related to the loss of potent estrogens. This can lead to the development of insulin resistance and endothelial dysfunction. Despite the challenges that exercise intolerance may pose for some postmenopausal women, evidence suggests that regular exercise and caloric restriction are crucial for weight management after menopause...
April 2017: Nursing for Women's Health
https://www.readbyqxmd.com/read/28386879/evaluation-of-fracture-risk-in-chronic-kidney-disease
#19
REVIEW
Pablo Antonio Ureña Torres, Martine Cohen-Solal
Chronic kidney disease (CKD) is associated with mineral and bone disorders (MBD) that are now considered as a syndrome. Bone fragility and a four to tenfold increased rate of skeletal fractures are often reported in CKD patients. The evaluation of the risk of these fractures in CKD patients should explore the same risk factors identified for the general population including low body weight, menopause, personal and familial history of osteoporosis, chronic inflammatory diseases, and corticosteroid therapy. The aim of this article is to provide a critical review of the tools used for the evaluation of bone loss and the risk of fracture in CKD patients, ranging from the measurement of bone mineral density (BMD), fracture risk assessment (Frax™), quantitative computed tomography (QCT), high-resolution peripheral quantitative computed tomography (HRpQTC), to circulating biomarkers of bone metabolism including vitamin D, parathyroid hormone (PTH), bone-specific alkaline phosphatase, osteocalcin, and some collagen type 1-related molecules indicators of bone remodeling...
April 6, 2017: Journal of Nephrology
https://www.readbyqxmd.com/read/28333235/ovarian-hormones-and-obesity
#20
Brigitte Leeners, Nori Geary, Philippe N Tobler, Lori Asarian
BACKGROUND: Obesity is caused by an imbalance between energy intake, i.e. eating and energy expenditure (EE). Severe obesity is more prevalent in women than men worldwide, and obesity pathophysiology and the resultant obesity-related disease risks differ in women and men. The underlying mechanisms are largely unknown. Pre-clinical and clinical research indicate that ovarian hormones may play a major role. OBJECTIVE AND RATIONALE: We systematically reviewed the clinical and pre-clinical literature on the effects of ovarian hormones on the physiology of adipose tissue (AT) and the regulation of AT mass by energy intake and EE...
May 1, 2017: Human Reproduction Update
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