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Multimodality monitoring

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https://www.readbyqxmd.com/read/29222120/targeting-cardiovascular-implant-infection-multimodality-and-molecular-imaging
#1
Jan M Sohns, Udo Bavendiek, Tobias L Ross, Frank M Bengel
Owing to their success in clinical practice, the prevalence of cardiovascular implants is continuously increasing. Implant infection is a relevant complication but remains a diagnostic challenge because echocardiography as a first-line test may be limited. Accordingly, a multimodality approach is increasingly used for diagnostic workup and supported by recent guidelines. As reviewed here, computed tomography and nuclear imaging provide incremental diagnostic value and may be combined in a single hybrid imaging session using positron emission tomography/computed tomography or single photon emission computed tomography/computed tomography...
December 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29221072/in-service-crosstalk-monitoring-tracing-and-lightpath-re-optimization-for-space-division-multiplexing-optical-networks
#2
Ruijie Luo, Nan Hua, Yufang Yu, Yongtai Jin, Xiaoping Zheng, Bingkun Zhou
In recent years, to enlarge the single-mode fibers (SMFs) transmission capacity, researchers focused on the dimension of space, which is a new degree of freedom that is being considered for optical fiber communication beyond WDM. Space-division multiplexing (SDM), including mode-division multiplexing (MDM) using multimode fibers (MMFs) or few-mode fibers (FMFs), and core multiplexing using multicore fibers (MCFs), has attracted much recent attention. In an SDM system, high-density spatial channels are tightly packed into a single fiber, thus making crosstalk among cores or modes a critical challenge due to fiber imperfections, bending, and twisting...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29210401/hybrid-magneto-plasmonic-liposomes-for-multimodal-image-guided-and-brain-targeted-hiv-treatment
#3
Asahi Tomitaka, Hamed Arami, Zaohua Huang, Andrea Raymond, Elizette Rodriguez, Yong Cai, Marcelo Febo, Yasushi Takemura, Madhavan Nair
Image-guided drug delivery is an emerging strategy in the field of nanomedicine. The addition of image guidance to a traditional drug delivery system is expected to achieve highly efficient treatment by tracking the drug carriers in the body and monitoring their effective accumulation in the targeted tissues. In this study, we developed multifunctional magneto-plasmonic liposomes (MPLs), a hybrid system combining liposomes and magneto-plasmonic nanoparticles for a triple-modality image-guided drug delivery...
December 6, 2017: Nanoscale
https://www.readbyqxmd.com/read/29209266/current-opportunities-for-clinical-monitoring-of-axonal-pathology-in-traumatic-brain-injury
#4
REVIEW
Parmenion P Tsitsopoulos, Sami Abu Hamdeh, Niklas Marklund
Traumatic brain injury (TBI) is a multidimensional and highly complex disease commonly resulting in widespread injury to axons, due to rapid inertial acceleration/deceleration forces transmitted to the brain during impact. Axonal injury leads to brain network dysfunction, significantly contributing to cognitive and functional impairments frequently observed in TBI survivors. Diffuse axonal injury (DAI) is a clinical entity suggested by impaired level of consciousness and coma on clinical examination and characterized by widespread injury to the hemispheric white matter tracts, the corpus callosum and the brain stem...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29193793/nanomaterial-enabled-wearable-sensors-for-healthcare
#5
REVIEW
Shanshan Yao, Puchakayala Swetha, Yong Zhu
Highly sensitive wearable sensors that can be conformably attached to human skin or integrated with textiles to monitor the physiological parameters of human body or the surrounding environment have garnered tremendous interest. Owing to the large surface area and outstanding material properties, nanomaterials are promising building blocks for wearable sensors. Recent advances in the nanomaterial-enabled wearable sensors including temperature, electrophysiological, strain, tactile, electrochemical, and environmental sensors are presented in this review...
November 30, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29191571/distinguish-self-and-hetero-perceived-stress-through-behavioral-imaging-and-physiological-features
#6
Michel Spodenkiewicz, Jonathan Aigrain, Nadège Bourvis, Séverine Dubuisson, Mohamed Chetouani, David Cohen
Stress reactivity is a complex phenomenon associated to multiple and multimodal expressions. Response to stressors has an obvious survival function and may be seen as an internal regulation to adapt to threat or danger. The intensity of this internal response can be assessed as the self-perception of the stress response. In species with social organization, this response also serves a communicative function, so-called hetero-perception. Our study presents multimodal stress detection assessment - a new methodology combining behavioral imaging and physiological monitoring for analyzing stress from these two perspectives...
November 27, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29176373/obstructive-sleep-apnea-and-bariatric-surgical-guidelines-summary-and-update
#7
Christel A L de Raaff, Nico de Vries, Bart A van Wagensveld
PURPOSE OF REVIEW: Increasing numbers of bariatric surgical procedures and the high prevalence of obstructive sleep apnea (OSA) in this population have resulted in a growing interest in the perioperative management of OSA in bariatric surgery. This review provides a summary of the first consensus guideline on this topic as well as an update of the newest literature available. RECENT FINDINGS: All bariatric patients should be screened for OSA and obesity hypoventilation syndrome (OHS) to reduce the risk of perioperative complications...
November 15, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/29175599/multimodal-imaging-for-a-theranostic-approach-in-a-murine-model-of-b-cell-lymphoma-with-engineered-nanoparticles
#8
Enza Torino, Luigi Auletta, Donatella Vecchione, Francesca Maria Orlandella, Giuliana Salvatore, Enrico Iaccino, Dario Fiorenza, Annamaria Grimaldi, Annamaria Sandomenico, Sandra Albanese, Daniela Sarnataro, Matteo Gramanzini, Camillo Palmieri, Giuseppe Scala, Ileana Quinto, Paolo Netti, Marco Salvatore, Adelaide Greco
Nanoparticles (NPs) are a promising tool for in vivo multimodality imaging and theranostic applications. Hyaluronic acid (HA)-based NPs have numerous active groups that make them ideal as tumor-targeted carriers. The B-lymphoma neoplastic cells express on their surfaces a clone-specific immunoglobulin receptor (Ig-BCR). The peptide A20-36 (pA20-36) selectively binds to the Ig-BCR of A20 lymphoma cells. In this work, we demonstrated the ability of core-shell chitosan-HA-NPs decorated with pA20-36 to specifically target A20 cells and reduce the tumor burden in a murine xenograft model...
November 22, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29174566/the-roles-of-pathology-in-targeted-therapy-of-women-with-gynecologic-cancers
#9
Rajmohan Murali, Rachel N Grisham, Robert A Soslow
The role of the pathologist in the multidisciplinary management of women with gynecologic cancer has evolved substantially over the past decade. Pathologists' evaluation of parameters such as pathologic stage, histologic subtype, grade and microsatellite instability, and their identification of patients at risk for Lynch syndrome have become essential components of diagnosis, prognostic assessment and determination of optimal treatment of affected women. Despite the use of multimodality treatment and combination cytotoxic chemotherapy, the prognosis of women with advanced-stage gynecologic cancer is often poor...
November 23, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29173429/intraoperative-neurophysiologic-monitoring-for-degenerative-cervical-myelopathy
#10
REVIEW
Masaaki Takeda, Satoshi Yamaguchi, Takafumi Mitsuhara, Masaru Abiko, Kaoru Kurisu
Multimodal intraoperative neurophysiologic monitoring is a reliable tool for detecting intraoperative spine injury and is recommended during surgery for degenerative cervical myopathy (DCM). Somatosensory evoked potential (SEP) can be used to monitor spine and peripheral nerve injury during positioning in surgery for DCM. Compensation technique for transcranial evoked muscle action potentials (tcMEPs) should be adopted in intraoperative monitoring during surgery for DCM. Free-running electromyography is a useful real-time monitoring add-on modality in addition to SEP and tcMEP...
January 2018: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/29165917/a-novel-multisite-confocal-system-for-rapid-ca-2-imaging-from-submicron-structures-in-brain-slices
#11
Luiza Filipis, Karima Ait Ouares, Philippe Moreau, Dimitrii Tanese, Valeria Zampini, Andrea Latini, Chun Bleau, Charlie Bleau, Jeremy Graham, Marco Canepari
In brain slices, resolving fast Ca(2+) fluorescence signals from submicron structures is typically achieved using two-photon or confocal scanning microscopy, an approach that limits the number of scanned points. The novel multiplexing confocal system presented here overcomes this limitation. This system is based on a fast spinning disk, a multimode diode laser and a novel high-resolution CMOS camera. The spinning disk, running at 20,000 rpm, has custom-designed spiral pattern that maximises light collection while rejecting out-of-focus fluorescence to resolve signals from small neuronal compartments...
November 22, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29155778/a-detailed-protocol-for-physiological-parameters-acquisition-and-analysis-in-neurosurgical-critical-patients
#12
Xiang Wu, Guoyi Gao, Junfeng Feng, Qing Mao, Jiyao Jiang
Intracranial pressure (ICP) monitoring is now widely used in neurosurgical critical patients. Besides mean ICP value, the ICP derived parameters such as ICP waveform, amplitude of pulse (AMP), the correlation of ICP amplitude and ICP mean (RAP), pressure reactivity index (PRx), ICP and arterial blood pressure (ABP) wave amplitude correlation (IAAC), and so on, can reflect intracranial status, predict prognosis, and can also be used as guidance of proper treatment. However, most of the clinicians focus only on the mean ICP value while ignoring these parameters because of the limitations of the current devices...
October 17, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29153963/shear-wave-elastography-swe-for-monitoring-of-treatment-of-tendinopathies-a-double-blinded-longitudinal-clinical-study
#13
Timm Dirrichs, Valentin Quack, Matthias Gatz, Markus Tingart, Björn Rath, Marcel Betsch, Christiane K Kuhl, Simone Schrading
RATIONALE AND OBJECTIVES: We aimed to investigate the diagnostic accuracy with which shear wave elastography (SWE) can be used to monitor response to treatment of tendinopathies, and to compare it to conventional ultrasound (US)-imaging methods (B-mode US (B-US) and power Doppler US (PD-US)). MATERIALS AND METHODS: A prospective Institutional Review Board-approved longitudinal study on 35 patients with 47 symptomatic tendons (17 Achilles-, 15 patellar-, and 15 humeral-epicondylar) who underwent standardized multimodal US and standardized clinical assessment before and after 6 months of treatment (tailored stretching exercise, sport break, and local Polidocanol) was carried out...
November 16, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29150090/graph-based-representation-of-behavior-in-detection-and-prediction-of-daily-living-activities
#14
Piotr Augustyniak, Grażyna Ślusarczyk
Various surveillance systems capture signs of human activities of daily living (ADLs) and store multimodal information as time line behavioral records. In this paper, we present a novel approach to the analysis of a behavioral record used in a surveillance system designed for use in elderly smart homes. The description of a subject's activity is first decomposed into elementary poses - easily detectable by dedicated intelligent sensors - and represented by the share coefficients. Then, the activity is represented in the form of an attributed graph, where nodes correspond to elementary poses...
November 10, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29144026/heart-rate-variability-and-implication-for-sport-concussion
#15
REVIEW
Scott A Bishop, Ryan T Dech, Przemyslaw Guzik, J Patrick Neary
Finding sensitive and specific markers for sports-related concussion is both challenging and clinically important. Such biomarkers might be helpful in the management of patients with concussion (i.e. diagnosis, monitoring and risk prediction). Among many parameters, blood flow-pressure metrics and heart rate variability (HRV) have been used to gauge concussion outcomes. Reports on the relation between HRV and both acute and prolonged concussion recovery are conflicting. While some authors report on differences in the low-frequency (LF) component of HRV during postural manipulations and postexercise conditions, others observe no significant differences in various HRV measures...
November 16, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29138636/stem-cell-tracking-technologies-for-neurological-regenerative-medicine-purposes
#16
REVIEW
Yongtao Zheng, Jiongwei Huang, Tongming Zhu, Ronggang Li, Zhifu Wang, Fukai Ma, Jianhong Zhu
The growing field of stem cell therapy is moving toward clinical trials in a variety of applications, particularly for neurological diseases. However, this translation of cell therapies into humans has prompted a need to create innovative and breakthrough methods for stem cell tracing, to explore the migration routes and its reciprocity with microenvironment targets in the body, to monitor and track the outcome after stem cell transplantation therapy, and to track the distribution and cell viability of transplanted cells noninvasively and longitudinally...
2017: Stem Cells International
https://www.readbyqxmd.com/read/29127152/objective-cardiovascular-assessment-in-the-neonatal-intensive-care-unit
#17
REVIEW
Eugene M Dempsey, Afif Faisal El-Khuffash
Traditionally, cardiovascular well-being was essentially based on whether the mean blood pressure was above or below a certain value. However, this singular crude method of assessment provides limited insight into overall cardiovascular well-being. Echocardiography has become increasingly used and incorporated into clinical care. New objective modality assessments of cardiovascular status continue to evolve and are being evaluated and incorporated into clinical care. In this review article, we will discuss some of the recent advances in objective assessment of cardiovascular well-being, including the concept of multimodal monitoring...
November 10, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29114276/predictive-value-of-motor-evoked-potential-monitoring-during-surgery-of-unruptured-anterior-circulation-cerebral-aneurysms
#18
Yasuhiro Yamada, Yoko Kato, Mohsen Nouri, Tsukasa Ganaha, Motoki Oheda, Kohei Ishihara, Shigeta Moriya, Akiyo Sadato, Joji Inamasu, Yuichi Hirose
Objective and Background: Surgery of unruptured aneurysms is always a great challenge to neurovascular surgeons because no postoperative neurological deficits should be expected postoperatively as the patients are fully asymptomatic before the surgery. Here, we present our experience with selective motor evoked potential (MEP) monitoring of our patients in a 2-year time window. Patients and Methods: From 2012 to 2014, 27 patients with unruptured intracranial aneurysms were operated in our institute with the help of MEP monitoring...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29104818/design-and-synthesis-of-new-sulfur-containing-hyperbranched-polymer-and-theranostic-nanomaterials-for-bimodal-imaging-and-treatment-of-cancer
#19
Blaze Heckert, Tuhina Banerjee, Shoukath Sulthana, Shuguftha Naz, Riyadh Alnasser, Deaven Thompson, Guillaume Normand, Jan Grimm, J Manuel Perez, Santimukul Santra
In this study, we have synthesized a new hyperbranched polyester polymer containing sulfur-pendants (HBPE-S) in the branching points. This HBPE-S polymer is composed of spherical shaped, aliphatic three-dimensional architecture with carboxylic acid groups on the surface. The presence of sulfur pendants in the polymeric cavities demonstrated important role in the effective encapsulation of Bi-DOTA complexes ([Bi] = 5.21 μM), when compared to the previously reported polymer without sulfur pendants (HBPE, [Bi] = 1...
March 21, 2017: ACS Macro Letters
https://www.readbyqxmd.com/read/29104746/multimodal-imaging-for-the-detection-of-brown-adipose-tissue-activation-in-women-a-pilot-study-using-nirs-and-infrared-thermography
#20
Valentina Hartwig, Letizia Guiducci, Martina Marinelli, Laura Pistoia, Tommaso Minutoli Tegrimi, Giorgio Iervasi, Alfredo Quinones-Galvan, Antonio L'Abbate
Purpose: A clear link between obesity and brown adipose tissue (BAT) dysfunction has been recently demonstrated. The purpose of this pilot study is to determine if near-infrared spectroscopy (NIRS) 2D imaging together with infrared thermography (IRT) is capable of identifying thermal and vascular response in the supraclavicular (SCV) areas after the ingestion of an oral glucose load as a thermogenic stimulation. Method: We studied two groups of women (obese versus lean) for discerning their different responses...
2017: Journal of Healthcare Engineering
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