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https://www.readbyqxmd.com/read/29334344/content-validity-and-satisfaction-with-a-caregiver-integrated-web-based-rehabilitation-intervention-for-persons-with-stroke
#1
Sarah Blanton, Sandra Dunbar, Patricia C Clark
Background Family members provide valuable contributions during rehabilitation after stroke, but frequently report higher incidences of burden, depression, and social isolation during caregiving. Thus, effective interventions to reduce stroke impact on the family are needed. Objectives To evaluate the content validity and satisfaction of a caregiver-focused web-based intervention designed to improve stroke survivor physical function while reducing caregiver negative outcomes. Methods Caregivers of individuals with stroke (N = 6) and expert rehabilitation researchers (N = 4) were presented with a novel, web-based intervention (CARE-CITE) designed to foster problem-solving and skill-building while facilitating caregiver involvement during constraint-induced movement therapy...
January 15, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29331209/ethical-and-end-of-life-considerations-for-neonates-requiring-ecmo-support
#2
REVIEW
Roxanne Kirsch, David Munson
ECMO has proven to be a life-saving intervention for a variety of disease entities with a high rate of survival in the neonatal population. However, ECMO requires clinical teams to engage in many ethical considerations. Even with ongoing improvements in technology and expertise, some patients will not survive a course of ECMO. An unsuccessful course of ECMO can be difficult to accept and cause a great deal of angst. These questions can result in real conflict both within the care team, and between the care team and the family...
January 10, 2018: Seminars in Perinatology
https://www.readbyqxmd.com/read/29327468/why-do-people-become-health-workers-analysis-from-life-histories-in-4-post-conflict-and-post-crisis-countries
#3
Sophie Witter, Haja Wurie, Justine Namakula, Wilson Mashange, Yotamu Chirwa, Alvaro Alonso-Garbayo
While there is a growing body of literature on how to attract and retain health workers once they are trained, there is much less published on what motivates people to train as health professions in the first place in low- and middle-income countries and what difference this makes to later retention. In this article, we examine patterns in expressed motivation to join the profession across different cadres, based on 103 life history interviews conducted in northern Uganda, Sierra Leone, Cambodia, and Zimbabwe...
January 12, 2018: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/29327114/anthropometric-characteristics-and-ovarian-cancer-risk-and-survival
#4
Albina N Minlikeeva, Kirsten B Moysich, Paul C Mayor, John L Etter, Rikki A Cannioto, Roberta B Ness, Kristen Starbuck, Robert P Edwards, Brahm H Segal, Sashikant Lele, Kunle Odunsi, Brenda Diergaarde, Francesmary Modugno
PURPOSE: Multiple studies have examined the role of anthropometric characteristics in ovarian cancer risk and survival; however, their results have been conflicting. We investigated the associations between weight change, height and height change and risk and outcome of ovarian cancer using data from a large population-based case-control study. METHODS: Data from 699 ovarian cancer cases and 1,802 controls who participated in the HOPE study were included. We used unconditional logistic regression adjusted for age, race, number of pregnancies, use of oral contraceptives, and family history of breast or ovarian cancer to examine the associations between self-reported height and weight and height change with ovarian cancer risk...
January 11, 2018: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29325127/inhibiting-trophoblast-par-1-overexpression-suppresses-sflt-1-induced-anti-angiogenesis-and-abnormal-vascular-remodeling-a-possible-therapeutic-approach-for-preeclampsia
#5
Yin Zhao, YanFang Zheng, XiaoXia Liu, QingQing Luo, Di Wu, XiaoPing Liu, Li Zou
STUDY QUESTION: Is it possible to improve vascular remodeling by inhibiting the excessive expression of protease activated receptor 1 (PAR-1) in trophoblast of abnormal placenta? SUMMARY ANSWER: Inhibition of trophoblast PAR-1 overexpression may promote placental angiogenesis and vascular remodeling, offering an alternative therapeutic approach for preeclampsia. WHAT IS KNOWN ALREADY: PAR-1 is high-affinity receptor of thrombin. Thrombin increases sFlt-1 secretion in trophoblast via the activation of PAR-1...
January 9, 2018: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29324946/realities-and-perspectives-of-adolescent-mothers-in-their-first-pregnancy
#6
Rita de Cássia Andrade Neiva Santos, Raimunda Magalhães da Silva, Maria Veraci Oliveira Queiroz, Herla Maria Furtado Jorge, Aline Veras Morais Brilhante
OBJECTIVE: to understand the trajectory of adolescents regarding the first pregnancy, contemplating realities and perspectives. METHOD: qualitative study, based on the Schütz theoretical framework, with 30 adolescents assisted in an outpatient clinic for adolescents in Fortaleza, Ceará, Brazil. From the narrative interviews carried out in the first semester of 2013, in the return for the first consultation of the puerperium, the communicative processes were identified, the central ideas and units of meanings expressed in the themes were abstracted: I was dating and became pregnant; realities and perspectives...
January 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29322514/the-yin-and-yang-of-yy1-in-tumor-growth-and-suppression
#7
REVIEW
Levon M Khachigian
Yin Yang-1 (YY1) is a zinc finger protein and member of the GLI-Kruppel family that can activate or inactivate gene expression depending on interacting partners, promoter context and chromatin structure, and may be involved in the transcriptional control of ∼10% of the total mammalian gene set. A growing body of literature indicates that YY1 is overexpressed in multiple cancer types and that increased YY1 levels correlate with poor clinical outcomes in many cancers. However the role of YY1 in the promotion or suppression of tumor growth remains controversial and its regulatory effects may be tumor cell type dependent at least in experimental systems...
January 11, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29316511/young-africans-social-representations-of-rape-in-their-hiv-related-creative-narratives-2005-2014-rape-myths-and-alternative-narratives
#8
Robyn Singleton, Kate Winskell, Siphiwe Nkambule-Vilakati, Gaëlle Sabben
Sexual violence is both a major human rights issue and an important driver of HIV infection in sub-Saharan Africa. While quantitative indicators of sexual violence have evolved to facilitate cross-national comparison and country-level decision making, qualitative findings typically remain constrained to single sites and populations. We analyzed social representations of sexual violence, specifically rape, in a sample of 1446 narratives about HIV written by young Africans between 2005 and 2014. The narratives were written at 5 discrete time points (2005, 2008, 2011, 2013 and 2014) by equal numbers of males and females aged 10-24 in urban and rural areas of Swaziland, Kenya, South-East Nigeria, Burkina Faso and Senegal...
December 26, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29311682/phylogenomics-illuminates-the-backbone-of-the-myriapoda-tree-of-life-and-reconciles-morphological-and-molecular-phylogenies
#9
Rosa Fernández, Gregory D Edgecombe, Gonzalo Giribet
The interrelationships of the four classes of Myriapoda have been an unresolved question in arthropod phylogenetics and an example of conflict between morphology and molecules. Morphology and development provide compelling support for Diplopoda (millipedes) and Pauropoda being closest relatives, and moderate support for Symphyla being more closely related to the diplopod-pauropod group than any of them are to Chilopoda (centipedes). In contrast, several molecular datasets have contradicted the Diplopoda-Pauropoda grouping (named Dignatha), often recovering a Symphyla-Pauropoda group (named Edafopoda)...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29306056/subclinical-maternal-depressive-symptoms-modulate-right-inferior-frontal-response-to-inferring-affective-mental-states-of-adults-but-not-of-infants
#10
Koji Shimada, Ryoko Kasaba, Takashi X Fujisawa, Nobuko Sakakibara, Shinichiro Takiguchi, Akemi Tomoda
BACKGROUND: Being a mother of young children increases the risk of depression characterised by deficits in inferring what a person is feeling, i.e., affective theory of mind (aToM). Despite the adverse consequences for mothers, children, families, and society as a whole, little is known of how the brain functions underlying aToM ability are affected by subclinical maternal depressive symptoms, and act as a risk indicator for major depressive disorders (MDD). METHODS: Thirty healthy mothers with varying levels of depressive symptoms underwent functional magnetic resonance imaging (fMRI) while performing mind-reading tasks based on the emotional expressions of adult eyes and infant faces...
December 26, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29305746/verbal-and-nonverbal-anticipatory-mechanisms-in-bilinguals
#11
Lorenzo Desideri, Paola Bonifacci
Empirical evidence collected so far has revealed that the bilingual advantage cannot be reduced to a single component of the executive functioning, and point to the need to understand the effects of bilingual experience on cognition as influencing a wider family of mental processes, including, but not limited to, cognitive control. The present study aims to explore a relatively underinvestigated domain of bilingual cognitive processes, namely anticipation, through a series of different paradigms tapping proactive and reactive mechanisms at different levels of cognitive complexity and linguistic components...
January 5, 2018: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/29304402/maternal-negative-emotional-expression-and-discipline-in-beijing-china-the-moderating-role-of-educational-attainment
#12
Feng Cheng, Yifang Wang, Xixian Wu, Zhuqing Su
The current study shows that parental punitive discipline places children at risk of developing internalizing and externalizing problems. Although some studies have analyzed the reasons for the use of discipline methods, little to no research has analyzed the moderating effects. In this study, we examine the relationship between maternal negative emotional expression and mothers' use of disciplinary methods (psychological aggression, corporal punishment and physical maltreatment) and the moderating effects of educational attainment in Chinese societies...
January 2, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29304203/primary-caregivers-in-a-network-context
#13
Christopher Steven Marcum, Sato Ashida, Laura M Koehly
Objectives: Caregiving to individuals affected by Alzheimer's disease and related dementia (ADRD) is a family-systems process where tasks are distributed between multiple caregivers in a network. We evaluate the extent to which multiple network members nominate one another as filling primary caregiver (PCG) roles and factors associated with nomination. Method: Data come from the Caregiving Roles and Expectations Networks project, which aimed to characterize the caregiving networks of families affected by ADRD...
January 3, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29301555/improving-partnerships-with-family-members-of-icu-patients-study-protocol-for-a-randomized-controlled-trial
#14
Daren K Heyland, Judy Davidson, Yoanna Skrobik, Amanda Roze des Ordons, Lauren J Van Scoy, Andrew G Day, Virginia Vandall-Walker, Andrea P Marshall
BACKGROUND: Over the last decade, health care delivery has shifted to partnering with patients and their families to improve health and quality of care, and to lower costs. Partnering with family members (FMs) of critically ill patients who lack capacity is particularly important for improving experiences and outcomes for both patients and FMs. How best to apply such partnering strategies, however, is yet unknown. The IMPACT trial will evaluate two interventions that enable partnerships with families of critically ill patients, each in a distinct content area, but similar in that they empower and support FMs...
January 4, 2018: Trials
https://www.readbyqxmd.com/read/29300304/behavioral-and-brain-activity-indices-of-cognitive-control-deficits-in-binge-drinkers
#15
Sean M Molnar, Lauren E Beaton, Joseph P Happer, Lee A Holcomb, Siyuan Huang, Donatello Arienzo, Ksenija Marinkovic
Heavy episodic drinking is prevalent among young adults and is a public issue of increasing importance. Its initiation and maintenance are associated with deficits in the capacity to inhibit automatic processing in favor of non-habitual responses. This study used functional magnetic resonance imaging (fMRI) to examine behavioral and brain activity indices of cognitive control during the Stroop task as a function of binge drinking. Heavy episodic drinkers (HED) reported consuming 5+/6+ drinks in two hours at least five times in the past six months and were compared to light drinkers (LED) who reported two or fewer binge episodes but were matched on demographics, intelligence and family history of alcoholism...
January 4, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29299493/dupuytren-s-disease-predicting-factors-and-associated-conditions-a-single-center-questionnaire-based-case-control-study
#16
Ilaria Morelli, Gianfranco Fraschini, Arianna E Banfi
Background: Conflicting studies link several conditions and risk factors to Dupuytren's disease (DD). A questionnaire-based case-control study was set to investigate associated conditions and clinical features of DD in a sample of Italian patients. The main purpose was the identification of predicting factors for: DD development; involvement of multiple rays; involvement of both hands; development of radial DD; development of recurrences and extensions. Methods: A self-administered questionnaire was used to investigate medical and drug histories, working and life habits, DD clinical features, familial history, recurrences and extensions...
November 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29295666/life-after-examining-the-relationship-between-sociobehavioral-factors-and-mental-health-among-african-american-ex-offenders
#17
Carlos C Mahaffey, Danelle Stevens-Watkins, Carl Leukefeld
Mental health problems are 3 times higher among prisoners than the general population. After release, reentry barriers and other factors can exacerbate mental problems. This study of 250 African American ex-offenders examines the relationship between sociobehavioral factors and mental health. Independent variables included self-reported health, alcohol use, employment, and history of mental problems before prison. Covariates included the number of immediate family with mental problems and the number of serious conflicts with family members or friends...
January 1, 2018: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29294995/experiences-of-elder-mistreatment-a-latent-profile-analysis
#18
Srinivasan Chokkanathan
Using a polyvictimization framework, this study seeks to identify profiles of older adults who are mistreated by their family members. Data were drawn from a survey ( n = 897) on the prevalence of elder mistreatment in rural India. This study involved 187 community-dwelling older adults (aged 61 years and above) with experiences of mistreatment in the year prior to the interview. Mistreatment was assessed through an adapted version of the Conflict Tactics Scale. Latent profile analysis was conducted to classify older adults into empirically derived clusters...
November 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29294947/the-impact-of-sexual-abuse-family-violence-conflict-spirituality-and-religion-on-anger-and-depressed-mood-among-adolescents
#19
Rannveig Sigurvinsdottir, Bryndis Bjork Asgeirsdottir, Sarah E Ullman, Inga Dora Sigfusdottir
Stressful life experiences, such as sexual abuse and family violence/conflict, relate to an increased risk of mental health problems. Religion and spirituality may prevent this negative impact, but religion and spirituality are lower among survivors of stressful life experiences. To explore this effect, we examined the relationship between childhood sexual abuse and family violence/conflict on anger and depressed mood. Survey data were collected from a large population-based sample of Icelandic adolescents ( N = 7,365) on their stressful life experiences, religion, spirituality, and mental health...
October 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29294869/a-qualitative-study-with-women-living-with-hiv-on-perceived-gender-norms-and-experiences-of-intimate-partner-violence-in-northern-vietnam
#20
Rebecca B Hershow, Madhura Bhadra, Nguyen Vu Tuyet Mai, Teerada Sripaipan, Tran Viet Ha, Vivian F Go
Although the prevalence of intimate partner violence (IPV) in Southeast Asia is one of the highest in the world, IPV remains understudied in the region, especially among women living with HIV (WLWH). This study aims to understand how gender and violence norms influence how WLWH interpret and prioritize violence as a health issue. We also explore whether HIV disclosure was seen as a trigger for IPV. We conducted in-depth interviews with 20 WLWH (median age = 35.5 years; range = 28-54 years) in northern Vietnam...
August 1, 2017: Journal of Interpersonal Violence
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