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Katarzyna Walkiewicz, Monika Gętek, Małgorzata Muc-Wierzgoń, Teresa Kokot, Ewa Nowakowska-Zajdel
Increasing numbers of reports about the role of adamalysins (ADAM) in malignant tumors are being published. To date, more than 30 representatives of this group, out of which about 20 occur in humans, have been described. The ADAM family is a homogeneous group of proteins which regulate, from the stage of embryogenesis, a series of processes such as cell migration, adhesion, and cell fusion. Half of them have proteolytic activity and are involved in the degradation of the extracellular matrix and the disintegration of certain protein complexes, thereby regulating the bioavailability of various growth factors...
2016: Postȩpy Higieny i Medycyny Doświadczalnej
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