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Food dye

Ismail Ocsoy, Nuran Isiklan, Sena Cansiz, Nalan Özdemir, Weihong Tan
Aptamer-functionalized magnetic graphene oxide conjugates loaded with indocyanine green (ICG) dye, or Apt@ICG@mGO, have been successfully developed for dual-targeted photothermal and photodynamic therapy. In general, a drug or its carrier or their dosage can be imprtant important issues in terms of toxicity. However, in this system, each component used is quite safe, biocompatibe and clean. For instance, ICG, a Food and Drug Administration (FDA) approved near-infrared (NIR) dye, serves as both a photothermal and photodynamic agent...
2016: RSC Advances
Yanan Zhang, Loong-Tak Lim
Colorimetric CO2 indicators were prepared by printing pH dyes (M-cresol purple or phenol red, tetrabutylammonium hydroxide, ethylcellulose, 1:2 ethanol:1-butanol solvent), using a commercially available thermal inkjet printer, on either cellulose paper or plastic transparency film. Indicators inks printed on the papers had higher sensitivity to CO2, greater color change, and more producible than those printed on plastic film. Varying the print intensities of the two pH dyes resulted in multiplexed indicators with tunable sensitivity and expanded detection concentration range towards CO2...
December 1, 2016: Talanta
Saehun Mun, Jisu Kim, David Julian McClements, Yong-Ro Kim, Yongdoo Choi
A whey protein isolate-rhodamine B conjugate (WPI-RB) was synthesized to visualize changes in the location of a protein emulsifier in oil-in-water emulsions during digestion. An oil-soluble dye (Nile Red) was used to visualize changes in the lipid phase during digestion. Protein-labeled and lipid-labeled emulsions were passed through a simulated gastrointestinal tract consisting of mouth, stomach, and intestinal phases, and changes in protein and lipid location and morphology were monitored using confocal laser scanning microscopy...
March 15, 2017: Food Chemistry
Monika Šuleková, Alexander Hudák, Miroslava Smrčová
Reversed-phase high performance liquid chromatography (RP-HPLC) for the determination of five synthetic food dyes (Quinoline Yellow E104, Sunset Yellow E110, Ponceau 4R E124, Tartrazine E102 and Carmine E120) in vitamins was used. The dyes were analyzed within 10 min using a column with stationary phase C 18 (250 mm × 4.6 mm, 5 μm) at 40 °C with isocratic elution, and the mobile phase contained acetonitrile and a mixture of CH₃COONa:CH₃OH (85:15, v/v) in a ratio of 10:90 (v/v) for yellow-colored capsules and 20:80 (v/v) for red-colored capsules, respectively...
October 17, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Ying Chen, Chao He, Jing-Jun Cheng, Wen-Yao Huang, Sheng-Wen Shao, Ya-Ping Jiang, Ling-Feng Dai, Jia-Fa Liu, Yi Song
This study aimed to conduct measurement uncertainty assessment of a new method for determination of Sudan colorants (Sudan I, II, III and IV) in food by high performance liquid chromatography (HPLC). Samples were extracted with organic solvents (hexane, 20% acetone) and first purified by magnesium trisilicate (2MgO·3SiO2). The Sudan colorants (Sudan I-IV) were also initially separated on C8 by gradient elution using acetonitrile and 0.1% (v/v) formic acid aqueous solution as the mobile phases and detected with diode-array detector (DAD)...
October 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
Nikolas T Weissmueller, Hoang Dung Lu, Amanda Hurley, Robert K Prud'homme
One factor limiting the expansion of nanomedicines has been the high cost of the materials and processes required for their production. We present a continuous, scalable, low cost nano-encapsulation process, Flash Nanoprecipitation (FNP) that enables the production of nanocarriers (NCs) with a narrow size distribution using zein corn proteins. Zein is a low cost, GRAS protein (having the FDA status of "Generally Regarded as Safe") currently used in food applications, which acts as an effective encapsulant for hydrophobic compounds using FNP...
October 16, 2016: Biomacromolecules
Qian Tian, Jian-Jun Feng, Jie Hu, Wen-Jun Zhao
In recent years, use of the DNA-intercalating dye propidium monoazide (PMA) in real-time PCR has been reported as a novel method to detect viable bacteria in different types of samples, such as food, environmental, and microbiological samples. In this study, viable cells of Acidovorax citrulli, the causal agent of bacterial seedling blight and fruit blotch, were selectively detected and differentiated from dead cells by real-time fluorescent polymerase chain reaction amplification after the bacterial solution was treated with the DNA-binding dye PMA...
October 14, 2016: Scientific Reports
Inyoung Choi, Jun Young Lee, Monique Lacroix, Jaejoon Han
A new colorimetric pH indicator film was developed using agar, potato starch, and natural dyes extracted from purple sweet potato, Ipomoea batatas. Both agar and potato starch are solid matrices used to immobilize natural dyes, anthocyanins. The ultraviolet-visible (UV-vis) spectrum of anthocyanin extract solutions and agar/potato starch films with anthocyanins showed color variations to different pH values (pH 2.0-10.0). Fourier transform infrared (FT-IR) and UV-vis region spectra showed compatibility between agar, starch, and anthocyanin extracts...
March 1, 2017: Food Chemistry
Yuanyuan Bu, Bo Sun, Aimin Zhou, Xinxin Zhang, Testuo Takano, Shenkui Liu
BACKGROUND: Abiotic stresses are serious threats to plant growth, productivity and result in crop loss worldwide, reducing average yields of most major crops. Although abiotic stresses might elicit different plant responses, most induce the accumulation of reactive oxygen species (ROS) in plant cells leads to oxidative damage. L-ascorbic acid (AsA, vitamin C) is known as an antioxidant and H2O2-scavenger that defends plants against abiotic stresses. In addition, vitamin C is also an important component of human nutrition that has to be obtained from different foods...
October 7, 2016: BMC Biotechnology
Mohd Ishtikhar, Rahisuddin, Mohsin Vahid Khan, Rizwan Hasan Khan
Quaternary amine of diethylaminoethyl rosin ester (QRMAE), chemically synthesized by rosin modified biocompatible cationic surfactant, has various biological applications in the field of pharmacy as well as used as food product additive. Here, we report biophysical insights in to the interaction mechanism of thymoquinone (TQ), copper nanoparticles (Cu-NPs) and QRMAE with bovine serum albumin (BSA) individually and also in complexes forms to determine their competitive binding affinity. We have also studied the aggregation-inhibition effects of Cu-NPs and TQ individually, as well as in complexes form in the presence of QRMAE surfactant which is responsible for induction of amorphous aggregates in BSA within hours of incubation at 65°C and physiological pH...
September 28, 2016: International Journal of Biological Macromolecules
Poornachandra Papireddy Vinayaka, Sander van den Driesche, Roland Blank, Muhammad Waseem Tahir, Mathias Frodl, Walter Lang, Michael J Vellekoop
A new miniaturized sensor system with an internal optical reference for the detection of mold growth is presented. The sensor chip comprises a reaction chamber provided with a culture medium that promotes the growth of mold species from mold spores. The mold detection is performed by measuring impedance changes with integrated electrodes fabricated inside the reaction chamber. The impedance change in the culture medium is caused by shifts in the pH (i.e., from 5.5 to 8) as the mold grows. In order to determine the absolute pH value without the need for calibration, a methyl red indicator dye has been added to the culture medium...
2016: Sensors
Miriam Hernández-Zamora, Fernando Martínez-Jerónimo, Eliseo Cristiani-Urbina, Rosa Olivia Cañizares-Villanueva
Nearly 7 00000 tons of dyes are produced annually throughout the world. Azo dyes are widely used in the textile and paper industries due to their low cost and ease of application. Their extensive use results in large volumes of wastewater being discharged into aquatic ecosystems. Large volume discharges constitute a health risk since many of these dyes, such as Congo Red, are elaborated with benzidine, a known carcinogenic compound. Information regarding dye toxicity in aquatic ecosystems is limited. Therefore, the aim of the present study was to evaluate the effect of Congo Red on survival and reproduction of Ceriodaphnia dubia...
September 26, 2016: Ecotoxicology
Ana M Ferreira, Pedro D O Esteves, Isabel Boal-Palheiros, Ana B Pereiro, Luís Paulo N Rebelo, Mara G Freire
This work unveils the formation of novel aqueous biphasic systems (ABS) formed by perfluoroalkylsulfonate-based ionic liquids (ILs) and a large number of carbohydrates (monosaccharides, disaccharides and polyols) aiming at establishing more benign alternatives to the salts commonly used. The respective ternary phase diagrams were determined at 298 K. The aptitude of the carbohydrates to induce phase separation closely follows their hydration capability, while the length of the IL cation/anion fluorinated chain also plays a crucial role...
February 21, 2016: Green Chemistry: An International Journal and Green Chemistry Resource: GC
Naoki Ochi, Tetsuya Okuda, Hisashi Fujii
Two unknown dyes (purple and purplish-red) were detected by TLC in two pickled vegetable (sakura-zuke daikon) samples containing Acid Red 52 (AR) and New Coccine as food colorants. HPLC with diode-array detection and LC/MS analyses suggested that the purple dye is monobrominated AR and the purplish-red dye is its N-desethyl derivative, which would be generated mainly during sample preparation. For the identification of the purple dye, a reference compound was prepared by bromination of AR followed by isolation of the monobrominated AR, the structure of which was elucidated as 4'-brominated AR (4'BrAR) by LC/ToF-MS and (1)H-NMR spectroscopy...
September 2016: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Katalin Solymosi, Beata Mysliwa-Kurdziel
Open tetrapyrroles termed phycobilins represent the major photosynthetic accessory pigments of several cyanobacteria and some eukaryotic algae such as the Glaucophyta, Cryptophyta and Rhodophyta. These pigments are covalently bound to so-called phycobiliproteins which are in general organized into phycobilisomes on the thylakoid membranes. In this work we first briefly describe the physico-chemical properties, biosynthesis, occurrence, in vivo localization and roles of the phycobilin pigments and the phycobiliproteins...
September 12, 2016: Mini Reviews in Medicinal Chemistry
Laura Espina, Diego García-Gonzalo, Rafael Pagán
In food preservation, the synergistic combination of different technologies aims to maximize the total lethality of the process and minimize the intensity of each hurdle. This is especially the case when at least one of the treatments can cause sublethal (reparable) injury in a great proportion of the population, so that sublethally injured cells can end up being entirely inactivated by the other hurdle(s). The selective medium plating technique (SMPT) is extensively used to enumerate bacterial sublethal injury after inimical treatments, being sodium chloride added to the recovery medium to detect damaged bacterial envelopes...
2016: Frontiers in Microbiology
Anton Korotkov, Alexander Andoralov, Vasiliy Amelin
The methodology for the identification and determination of 492 different toxicants from a single sample in food and feed by high-resolution quadrupole time-of-flight MS in combination with HPLC has been presented. The sample preparation is easy. The analytes are pesticides of different classes, including mycotoxins, veterinary drugs, and synthetic dyes. A scheme for the identification and determination of toxicants using the standard addition method has been given. The RSDs of the analytical results presented are ≤0...
September 2, 2016: Journal of AOAC International
Youngnam Kang, Hajime Sato, Mitsuru Saito, Dong Xu Yin, Sook Kyung Park, Seog Bae Oh, Yong Chul Bae, Hiroki Toyoda
Anandamide (AEA) and N-oleoylethanolamine (OEA) are produced in the intestine and brain during fasting and satiety, respectively. Subsequently, AEA facilitates food intake via activation of cannabinoid type-1 receptors (CB1Rs) while OEA decreases food intake via activation of peroxisome proliferator-activated receptor-α (PPARα) and/or G-protein-coupled receptor 119 (GPR119). Neuronal activity in the gastrointestinal region of the autonomic insula (GI-Au-I) that rostrally adjoins the gustatory insula (Gu-I) increases during fasting, enhancing appetite while umami and sweet taste sensations in Gu-I enhances appetite in GI-Au-I, strongly suggesting the presence of a neural interaction between the Gu-I and GI-Au-I which changes depending on the concentrations of AEA and OEA...
2016: Scientific Reports
Yahui Guo, Qingmin Chen, Yiting Qi, Yunfei Xie, He Qian, Weirong Yao, Renjun Pei
A novel ratiometric method with label-free and dual-wavelength signal outputs was developed for DNA detection by employing two kinds of structure-specific dyes that characterising interaction-responsive emission property. The ratiometric platform for the fluorescent detection of DNA was based on target-induced structural transformation from stem-loop structure incorporating split G-quadruplex (SISG) to doubule-strand DNA (dsDNA). The SISG conformation will be disrupted upon binding to the target DNA of perfect complementary sequence, resulting in fluorescence decrease at 610nm as NMM releases from SISG and fluorescence increase at 450nm as DAPI inserts into the dsDNA...
August 13, 2016: Biosensors & Bioelectronics
M Imran, Ammar B Yousaf, Xiao Zhou, Kuang Liang, Yi-Fan Jiang, An-Wu Xu
Oxygen-sensitive photoreversible intelligent ink capable of assessment with the human eye is an ongoing demand in the modern era. In the food industry, redox-dye-based oxygen indicator films have been proposed, but the leaching of dyes from the film that contaminates the food is one unsolved issue. On the other hand, it is also highly desirable to develop rewritable paper that significantly reduces the pressure on modern society for the production and consumption of paper. Herein, we have developed an oxygen-deficient TiO2 - x/methylene blue (MB) sol without relying on external sacrificial electron donors (SEDs) for photoreversible color switching...
September 6, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
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