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https://www.readbyqxmd.com/read/29932981/prioritization-before-risk-assessment-the-viability-of-uncertain-data-on-food-contact-materials
#1
Eelco N Pieke, Kit Granby, Bruno Teste, Jørn Smedsgaard, Gilles Rivière
The shortage of data on non-intentionally added substances (NIAS) present in food contact material (FCM) limits the ability to ensure food safety. Recent strategies in analytical method development allow investigating NIAS by using chemical exploration; but this has not been sufficiently investigated in risk assessment context. Here, exploration is applied on two paperboard FCM samples followed by risk prioritization for chemicals that can potentially migrate to food. Concentration estimates from exploration are converted into a tentative exposure assessment, while predicted chemical structures are assessed using quantitative structure-activity relationships (QSAR) models for carcinogenicity, mutagenicity, and reproductive toxicity...
June 19, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29928765/interactions-with-8-anilinonaphthalene-1-sulfoniac-acid-ans-and-surface-hydrophobicity-of-black-gram-vigna-mungo-phaseolin
#2
Maithili Deshpande, S K Sathe
Surface hydrophobicity (SH) properties of the trimeric storage protein phaseolin (black gram phaseolin [BGP]) of black gram (Vigna mungo) were investigated using 8-anilinonaphthalene-1-sulfonate (ANS) as an extrinsic fluorescent probe. The emission maxima of fluorescence spectra of BGP:ANS complex were blue-shifted to 455 nm as compared to 515 nm for the free ANS. Saturation binding occurred at a dye-to-protein ratio of about 30:1. The quantum yield of the complex increased with increasing ionic strength. The Kd values were 1...
June 21, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29908862/simple-colorimetric-method-to-determine-the-in-vitro-antioxidant-activity-of-different-monoterpenes
#3
Nehuen Noacco, Boris Rodenak-Kladniew, Margarita García de Bravo, Guillermo R Castro, German A Islan
The development of simple, fast and reproducible techniques that provide information about the antioxidant activity (AA) of different compounds is essential to screen and discover new molecules with potential applications in the therapeutic, cosmetic, toxicological and food fields. Here, a novel and simple colorimetric method ("BCB assay") is proposed for measuring the AA of chemical compounds by protection of the reporter dye Brilliant Cresyl Blue (BCB) from loss of color due to oxidation by hypochlorite (a physiological oxidant)...
June 14, 2018: Analytical Biochemistry
https://www.readbyqxmd.com/read/29895346/simultaneous-extraction-and-determination-of-allura-red-e129-and-brilliant-blue-fcf-e133-in-foodstuffs-by-column-solid-phase-spectrophotometry
#4
Abdullah Taner Bişgin
Background: Allura Red (AR) and Brilliant Blue FCF (BB) are highly water-soluble synthetic food dyes used to color baked goods, beverages, candies, jellies, sausages, etc. Although AR and BB are not entirely toxic, they can lead to health problems in humans. Objective: The aim of the study was to develop a column solid-phase extraction (SPE) and preconcentration method based on the adsorption on a Diaion HP-20 polymeric resin for simultaneous spectrophotometric determination of AR and BB. Methods: The column SPE method was used, and the analytical parameters of the SPE method, such as pH, sample flow rate, sample volume, etc...
June 12, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29894959/selective-and-sensitive-spectrophotometric-method-to-determine-trace-amounts-of-copper-metal-ions-using-amaranth-food-dye
#5
Adham A El-Zomrawy
Copper is an essential element in some biological processes in organisms, so it was important to find ways to identify trace amounts of it. Minimal amounts of copper ions can be determined in aqueous solutions in the spectrophotometric method suggested in this study. The method depends on the reaction between Cu(II) and Amaranth dye at the pH 6.0. The gradual disappearance of Amaranth colour at 520 nm occurring with an increase of Cu(II) concentration from 0.13 up to 2.0 μg cm-3 . The molar absorptivity coefficient and Sandell's sensitivity of the complex are found to be 0...
June 4, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29882932/leveraging-engineering-of-indocyanine-green-encapsulated-polymeric-nanocomposites-for-biomedical-applications
#6
REVIEW
Ya-Hui Han, Ranjith Kumar Kankala, Shi-Bin Wang, Ai-Zheng Chen
In recent times, photo-induced therapeutics have attracted enormous interest from researchers due to such attractive properties as preferential localization, excellent tissue penetration, high therapeutic efficacy, and minimal invasiveness, among others. Numerous photosensitizers have been considered in combination with light to realize significant progress in therapeutics. Along this line, indocyanine green (ICG), a Food and Drug Administration (FDA)-approved near-infrared (NIR, >750 nm) fluorescent dye, has been utilized in various biomedical applications such as drug delivery, imaging, and diagnosis, due to its attractive physicochemical properties, high sensitivity, and better imaging view field...
May 24, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29874280/highly-structured-genetic-diversity-of-bixa-orellana-var-urucurana-the-wild-ancestor-of-annatto-in-brazilian-amazonia
#7
Gabriel Dequigiovanni, Santiago Linorio Ferreyra Ramos, Alessandro Alves-Pereira, Eliane Gomes Fabri, Doriane Picanço-Rodrigues, Charles Roland Clement, Paul Gepts, Elizabeth Ann Veasey
Annatto (Bixa orellana L.) is a tropical American crop, commercially valuable due to its application in the food and cosmetics industries as a natural dye. The wild ancestor of cultivated annatto is B. orellana var. urucurana. Although never cultivated, this variety occurs in open forests and anthropogenic landscapes, and is always associated with riparian environments. In this study, we evaluated the genetic diversity and structure of B. orellana var. urucurana populations in Brazilian Amazonia using 16 microsatellite loci...
2018: PloS One
https://www.readbyqxmd.com/read/29868350/clinically-applicable-perfluorocarbon-loaded-nanoparticles-for-in-vivo-photoacoustic-19-f-magnetic-resonance-and-fluorescent-imaging
#8
Edyta Swider, Khalid Daoudi, Alexander H J Staal, Olga Koshkina, N Koen van Riessen, Eric van Dinther, I Jolanda M de Vries, Chris L de Korte, Mangala Srinivas
Photoacoustic imaging (PAI) is an emerging biomedical imaging technique that is now coming to the clinic. It has a penetration depth of a few centimeters and generates useful endogenous contrast, particularly from melanin and oxy-/deoxyhemoglobin. Indocyanine green (ICG) is a Food and Drug Administration-approved contrast agents for human applications, which can be also used in PAI. It is a small molecule dye with limited applications due to its fast clearance, rapid protein binding, and bleaching effect. Methods: Here, we entrap ICG in a poly(lactic- co -glycolic acid) nanoparticles together with a perfluorocarbon (PFC) using single emulsion method...
2018: Nanotheranostics
https://www.readbyqxmd.com/read/29846845/associations-of-dietary-fat-with-risk-of-early-neoplasia-in-the-proximal-colon-in-a-population-based-case-control-study
#9
Allen Mo, Rong Wu, James P Grady, Matthew P Hanley, Margaret Toro, Helen Swede, Thomas J Devers, Terryl J Hartman, Daniel W Rosenberg
PURPOSE: Excess dietary fat consumption is strongly associated with the risk of colorectal cancer, but less is known about its role in the earliest stages of carcinogenesis, particularly within the proximal colon. In the following case-control study, we evaluated the relationship between the intake of dietary fats and the frequency of early proximal neoplasia [aberrant crypt foci (ACF) or polyps], detectable by high-definition colonoscopy with contrast dye-spray. METHODS: Average-risk screening individuals underwent a high-definition colonoscopy procedure as part of larger ongoing clinical study of precancerous lesions in the proximal colon...
May 30, 2018: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29843867/simultaneous-detection-of-yersinia-enterocolitica-and-listeria-monocytogenes-in-foodstuffs-by-capillary-electrophoresis-and-microchip-capillary-electrophoresis-laser-induced-fluorescence-detector
#10
Yongru Li, Hongwei Su, Yajia Lan
Background: Food safety is one of the most important public health problems in the world,and pathogenic bacterium is a major factor causing serious foodborne diseases. Objective: Two methods of duplex PCR combined with capillary electrophoresis laser-induced fluorescence detector (CE-LIF) and microchip capillary electrophoresis laser-induced fluorescence detector (MCE-LIF) have been developed for the simultaneous detection of Yersinia enterocolitica and Listeria monocytogenes in various foods. The specific conservative sequences of these two bacteria were amplified...
May 29, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29843864/simultaneous-preconcentration-and-determination-of-brilliant-blue-and-sunset-yellow-in-foodstuffs-by-solid-phase-extraction-combined-uv-vis-spectrophotometry
#11
Abdullah Taner Bişgin
Background: Brilliant Blue and Sunset Yellow, two highly water-soluble synthetic food dyes, are the most popular food dyes used and consumed. Although they are not highly toxic, some health problems can be observed when excessive amounts of food products containing these dyes are consumed. Objectives: The aim of the study was to develop a simultaneous UV-Vis combined solid-phase extraction method, based on the adsorption onto Amberlite XAD-8 resin, for determination of Brilliant Blue and Sunset Yellow dyes...
May 29, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29808790/determination-of-aniline-4-aminoazobenzene-and-2-naphthol-in-the-color-additive-d-c-red-no-17-using-ultra-high-performance-liquid-chromatography
#12
H H Wendy Yang, Adrian Weisz
Specifications in the U.S. Code of Federal Regulations for the color additive D&C Red No. 17 (R17, ColourIndex No. 26100) limit the levels of the dye's intermediates, aniline (AN), 2-naphthol (β-naphthol, BN), and 4-aminoazobenzene (4AAB), to 0.2, 0.2, and 0.1%, respectively. The present work reports the development and application of an ultra-HPLC method for the quantitative determination of these impurities in R17. A 1.7 μm particle size C-18 column was used with 0.2 M ammonium acetate and acetonitrile as the eluents...
May 18, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29803072/green-synthesis-of-sno-2-quantum-dots-using-parkia-speciosa-hassk-pods-extract-for-the-evaluation-of-anti-oxidant-and-photocatalytic-properties
#13
Shamima Begum, Md Ahmaruzzaman
In the present study, microwave heating method was established for the biosynthesis of SnO2 Quantum dots (QDs) using Parkia speciosa Hassk pods extract. The as-synthesized quantum dots have been characterized by various techniques such as UV, XRD, EDX, TEM, HRTEM, SAED and FTIR spectroscopy. The biosynthesized SnO2 QDs was employed for the first time as an efficient photocatalyst for the degradation of a food dye, acid yellow 23 dye from aqueous phase under the UV254 light. Various parameters, such as the effect of catalyst dose, the initial concentration of acid yellow 23 dye (AY23), pH of the solution and irradiation time on the photodegradation process are also studied for efficient and better use of the synthesized SnO2 QDs as a catalyst...
May 1, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29800620/application-of-edible-paraffin-oil-for-cationic-dye-removal-from-water-using-emulsion-liquid-membrane
#14
Sina Zereshki, Parisa Daraei, Amin Shokri
Using an emulsion liquid membrane based on edible oils is investigated for removing cationic dyes from aqueous solutions. There is a great potential for using edible oils in food industry extraction processes. The parameters affecting the stability of the emulsion and the extraction rate were studied. These parameters were the emulsification time, the stirring speed, the surfactant concentration, the internal phase concentration, the feed phase concentration, the volume ratio of internal phase to organic phase and the treat ratio...
May 18, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29794221/aldehyde-dehydrogenase-3a1-activation-prevents-radiation-induced-xerostomia-by-protecting-salivary-stem-cells-from-toxic-aldehydes
#15
Julie P Saiki, Hongbin Cao, Lauren D Van Wassenhove, Vignesh Viswanathan, Joshua Bloomstein, Dhanya K Nambiar, Aaron J Mattingly, Dadi Jiang, Che-Hong Chen, Matthew C Stevens, Amanda L Simmons, Hyun Shin Park, Rie von Eyben, Eric T Kool, Davud Sirjani, Sarah M Knox, Quynh Thu Le, Daria Mochly-Rosen
Xerostomia (dry mouth) is the most common side effect of radiation therapy in patients with head and neck cancer and causes difficulty speaking and swallowing. Since aldehyde dehydrogenase 3A1 (ALDH3A1) is highly expressed in mouse salivary stem/progenitor cells (SSPCs), we sought to determine the role of ALDH3A1 in SSPCs using genetic loss-of-function and pharmacologic gain-of-function studies. Using DarkZone dye to measure intracellular aldehydes, we observed higher aldehyde accumulation in irradiated Aldh3a1 -/- adult murine salisphere cells and in situ in whole murine embryonic salivary glands enriched in SSPCs compared with wild-type glands...
May 24, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29786840/spray-drying-of-milk-blackberry-pulp-mixture-effect-of-carrier-agent-on-the-physical-properties-of-powder-water-sorption-and-glass-transition-temperature
#16
Matheus Boeira Braga, Sandra Cristina Dos Santos Rocha, Miriam Dupas Hubinger
Spray dryer was used to produce particles from a milk-blackberry pulp mixture (25%:75% (w/w)). Maltodextrin 10DE and 20DE and gum Arabic were used as adjuvants in order to improve powder quality. The particles were analyzed with emphasis on physical and physicochemical characteristics: moisture content, bulk density, particle size, morphology, water activity, anthocyanins retention, anthocyanins content, hygroscopicity, solubility, water sorption, and glass transition temperature. The best results were obtained for the paste composition of 25% concentrated milk-70% blackberry pulp-5% gum Arabic, yielding high anthocyanins retention (>87...
May 22, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29785517/optimization-and-enhancement-of-textile-reactive-remazol-black-b-decolorization-and-detoxification-by-environmentally-isolated-ph-tolerant-pseudomonas-aeruginosa-ky284155
#17
Rasha A Hashem, Reham Samir, Tamer M Essam, Amal E Ali, Magdy A Amin
Azo dyes are complex derivatives of diazene used in food and textile manufacture. They are highly recalcitrant compounds, and account for severe environmental and health problems. Different strains of Pseudomonas species were isolated from textile wastewater effluents. The bioconversion of Remazol black B (a commonly used water soluble dye) by Pseudomonas aeruginosa was observed in static conditions. The bio-decolorization process was optimized by a multi factorial Plackett-Burman experimental design. Decolorization of 200 mg L-1 reached 100% in 32 h...
May 21, 2018: AMB Express
https://www.readbyqxmd.com/read/29782142/projection-based-3d-printing-of-cell-patterning-scaffolds-with-multi-scale-channels
#18
Dai Xue, Yancheng Wang, Jiaxin Zhang, Deqing Mei, Yue Wang, Shaochen Chen
To fully actualize artificial, cell-laden biological models in tissue engineering, such as 3D organoids and organs-on-a-chip systems, cells need to be patterned such that they can precisely mimic natural microenvironments in vitro. Despite increasing interest in this area, patterning cells at multiscales (~10 μm - 10 mm) remains a significant challenge in bioengineering. Here we report a projection-based 3D printing system that achieves rapid and high-resolution fabrication of hydrogel scaffolds featuring intricate channels for multi-scale cell patterning...
May 21, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29780521/translating-molecular-detections-into-a-simple-temperature-test-using-a-target-responsive-smart-thermometer
#19
Jingjing Zhang, Hang Xing, Yi Lu
While it has been well recognized that affordable and pocket-size devices play a major role in environmental monitoring, food safety and medical diagnostics, it often takes a tremendous amount of resources to develop such devices. Devices that have been developed are often dedicated devices that can detect only one or a few targets. To overcome these limitations, we herein report a novel target-responsive smart thermometer for translating molecular detection into a temperature test. The sensor system consists of a functional DNA-phospholipase A2 (PLA2 ) enzyme conjugate, a liposome-encapsulated NIR dye, and a thermometer interfaced with a NIR-laser device...
April 28, 2018: Chemical Science
https://www.readbyqxmd.com/read/29776453/dye-residue-analysis-in-raw-and-processed-aquaculture-products-matrix-extension-of-aoac-international-official-method-%C3%A2-2012-25
#20
Wendy C Andersen, Christine R Casey, Tara J Nickel, Susan L Young, Sherri B Turnipseed
Background : Triphenylmethane dyes and metabolites are known or suspected mutagens and areprohibited in animals intended for human consumption. Despite toxicity, triphenylmethane dyes are used illegally as inexpensive treatments for fungal and parasite infections in aquatic animals. Objective: AOAC INTERNTIONAL Official Method ℠ 2012.25 for the LC-MS/MS determination of malachite green, crystal violet, brilliant green, and metabolites leucomalachite green and leucocrystal violet in seafood products was previously validated for finfish (trout, salmon, catfish, and tilapia) and shrimp, but had not been fully validated for other types of aquacultured products such as eel, molluscan shellfish, or frog or for processed seafoods...
May 18, 2018: Journal of AOAC International
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