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Jin Gu, He-Shui Shi, Ping Han, Jie Yu, Gui-Na Ma, Sheng Wu
This study sought to compare the image quality and radiation dose of coronary computed tomography angiography (CCTA) from prospectively triggered 128-slice CT (128-MSCT) versus dual-source 64-slice CT (DSCT). The study was approved by the Medical Ethics Committee at Tongji Medical College of Huazhong University of Science and Technology. Eighty consecutive patients with stable heart rates lower than 70 bpm were enrolled. Forty patients were scanned with 128-MSCT, and the other 40 patients were scanned with DSCT...
October 18, 2016: Scientific Reports
Clara Park, Tatjana Gruber-Rouh, Doris Leithner, Amelie Zierden, Mortiz H Albrecht, Julian L Wichmann, Boris Bodelle, Mohamed Elsabaie, Jan-Erik Scholtz, Moritz Kaup, Thomas J Vogl, Martin Beeres
BACKGROUND: Evaluation of latest generation automated attenuation-based tube potential selection (ATPS) impact on image quality and radiation dose in contrast-enhanced chest-abdomen-pelvis computed tomography examinations for gynaecologic cancer staging. METHODS: This IRB approved single-centre, observer-blinded retrospective study with a waiver for informed consent included a total of 100 patients with contrast-enhanced chest-abdomen-pelvis CT for gynaecologic cancer staging...
October 10, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
Zhanguo Sun, Wenjian Xu, Shuran Huang, Yueqin Chen, Xiang Guo, Zhitao Shi
BACKGROUND: Despite dual-source computed tomography (DSCT) technology has been performed well on adults or infants with heart disease, specific knowledge about children with congenital pulmonary valve stenosis (PS) remained to be established. OBJECTIVES: This original research aimed to establish a professional approach of DSCT performing technology on children and to assess the image quality performed by DSCT to establish a diagnostic evaluation for children with PS...
April 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
Stefanie Mangold, Julian L Wichmann, U Joseph Schoepf, Damiano Caruso, Christian Tesche, Daniel H Steinberg, Akos Varga-Szemes, Andrew C Stubenrauch, Richard R Bayer, Matthew Biancalana, Konstantin Nikolaou, Carlo N De Cecco
PURPOSE: To investigate diagnostic accuracy of 3(rd)-generation dual-source CT (DSCT) coronary angiography in obese and non-obese patients. METHODS: We retrospectively analyzed 76 patients who underwent coronary CT angiography (CCTA) and invasive coronary angiography. Prospectively ECG-triggered acquisition was performed with automated tube voltage selection (ATVS). Patients were dichotomized based on body mass index in groups A (<30 kg/m(2), n = 37) and B (≥30 kg/m(2), n = 39) and based on tube voltage in groups C (<120 kV, n = 46) and D (120 kV, n = 30)...
September 28, 2016: European Radiology
Arash Mahdavi, Ali Mohammadzadeh, Golsa Joodi, Mohammad Reza Tabatabaei, Farhad Sheikholeslami, Marzieh Motevalli
BACKGROUND: There are numerous studies that address the diagnostic value of dual-source computed tomography (DSCT) as an alternative to conventional coronary angiography (CCA). However, the benefit of application of DSCT in a real world clinical setting should be evaluated. OBJECTIVES: To determine the diagnostic accuracy of DSCT technique compared with CCA as the gold standard method in detection of coronary artery stenosis among symptomatic patients who are presented to a referral cardiovascular center during daily clinical practice...
April 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
Ci He, Peng Wang, Fei-Zhou Du, Jian-Wen Gu, Zhi-Gang Yang
OBJECTIVE: To evaluate the epidemiological and morphological characteristics of coronary plaque in diabetic patients with symptomatic coronary heart disease (CHD) by dual-source computed tomography (DSCT). MATERIALS AND METHODS: From June 2013 to December 2014, 267 consecutive patients with type 2 diabetes mellitus were examined by DSCT. Plaque type, distribution, as well as extent and obstructive characteristics were determined for each segment. RESULTS: A total of 225 patients were included in the final study...
September 14, 2016: Current Vascular Pharmacology
Houda Bahig, Jacques de Guise, Toni Vu, Carl Chartrand-Lefebvre, Danis Blais, Martin Lebeau, Nhu-Tram Nguyen, David Roberge
PURPOSE: The purpose of the study was to determine the extent of displacement of the pulmonary vein antrums resulting from the intrinsic motion of the heart using 4D cardiac dual-source computed tomography (DSCT). METHODS: Ten consecutive female patients were enrolled in this prospective planning study. In breath-hold, a contrast-injected cardiac 4-dimensional (4D) computed tomography (CT) synchronized to the electrocardiogram was obtained using a prospective sequential acquisition method including the extreme phases of systole and diastole...
2016: Curēus
Thomas Henzler, Nils Vogler, Bettina Lange, Franz Dally, Mathias Meyer, Stefan O Schoenberg, Maliha Sadick
OBJECTIVES: To prospectively evaluate the diagnostic value and radiation dose of time-resolved CT-Angiography (4D-CTA) in pediatric patients with venous malformations using 3rd generation dual-source CT (DSCT) at 70 kVp tube voltage. METHODS: Between November 2014 and August 2015, seven children (2 male, 5 female; median age, 9 years; range 3-12 years) with suspected peripheral, non-cerebral, venous malformations were included in this feasibility study and underwent US, MRI and 4D-CTA...
2016: European Journal of Radiology Open
Lloyd M Felmly, Carlo N De Cecco, U Joseph Schoepf, Akos Varga-Szemes, Stefanie Mangold, Andrew D McQuiston, Sheldon E Litwin, Richard R Bayer, Thomas J Vogl, Julian L Wichmann
PURPOSE: To investigate feasibility, image quality and safety of low-tube-voltage, low-contrast-volume comprehensive cardiac and aortoiliac CT angiography (CTA) for planning transcatheter aortic valve replacement (TAVR). MATERIALS AND METHODS: Forty consecutive TAVR candidates prospectively underwent combined CTA of the aortic root and vascular access route (270 mgI/ml iodixanol). Patients were assigned to group A (second-generation dual-source CT [DSCT], 100 kV, 60 ml contrast, 4...
August 23, 2016: European Radiology
Sock Keow Tan, Chai Hong Yeong, Kwan Hoong Ng, Yang Faridah Abdul Aziz, Zhonghua Sun
OBJECTIVES: This study aimed to measure the absorbed doses in selected organs for prospectively ECG-triggered coronary computed tomography angiography (CCTA) using five different generations CT scanners in a female adult anthropomorphic phantom and to estimate the effective dose (HE). MATERIALS AND METHODS: Prospectively ECG-triggered CCTA was performed using five commercially available CT scanners: 64-detector-row single source CT (SSCT), 2 × 32-detector-row-dual source CT (DSCT), 2 × 64-detector-row DSCT and 320-detector-row SSCT scanners...
2016: PloS One
Stephanie Zesch, Stephanie Panzer, Wilfried Rosendahl, John W Nance, Stefan O Schönberg, Thomas Henzler
PURPOSE: The aim of this study was to systematically reinvestigate the first human mummy that was ever analyzed with X-ray imaging in 1896, using dual-source computed tomography (DSCT) in order to compare the earliest and latest imaging technologies, to estimate preservation, age at death, sex, anatomical variants, paleopathological findings, mummification, embalming and wrapping of the child mummy from ancient Egypt. Radiocarbon dating was used to determine the mummy's age and to specify the child's living period in the Egyptian chronology...
2016: European Journal of Radiology Open
Eftychia Demerouti, Athanassios Manginas, Emmanouil Petrou, Spyridoula Katsilouli, Panagiotis Karyofillis, George Athanassopoulos, George Karatasakis, Ioannis Iakovou, Konstantinos Mihas, Irene Mastorakou
INTRODUCTION: Left Main Compression Syndrome (LMCS) represents an entity described as the extrinsic compression of the left main coronary artery (LMCA) by a dilated pulmonary artery (PA) trunk. We examined the presence of LMCS in patients with pulmonary hypertension (PH) using dual-source computed tomography (DSCT), as a non-invasive diagnostic tool. METHODS: The following parameters were measured: PA trunk diameter (PAD), the distance between PAD and LMCA (LMPA) and the distance between PA and aorta (AoPA)...
2016: Open Cardiovascular Medicine Journal
Taewoong Um, Dong Hoon Lee, Joon-Won Kang, Eun Young Kim, Young Hee Yoon
Both diabetic retinopathy (DR) and coronary heart disease (CHD) are clinically significant in diabetic patients. We investigated the correlation between the severity of DR and the presence and severity of CHD among type 2 diabetic patients. A total of 175 patients who were examined at the DR clinic and underwent dual-source computed tomography (DSCT) angiography within 6 months were included. The degree of DR was graded as no DR, nonproliferative DR (NPDR), and proliferative DR (PDR). The severity of CHD and the numbers of significant stenotic coronary artery on DSCT angiography according to DR grade were assessed...
August 2016: Journal of Korean Medical Science
Henning D Popp, Mathias Meyer, Susanne Brendel, Wiltrud Prinzhorn, Nicole Naumann, Christel Weiss, Wolfgang Seifarth, Stefan O Schoenberg, Wolf-K Hofmann, Thomas Henzler, Alice Fabarius
PURPOSE: Computed tomography (CT) scans are an important source of ionizing irradiation (IR) in medicine that can induce a variety of DNA damage in human tissues. With technological improvements CT scans at reduced absorbed doses became feasible presumably lowering genotoxic side effects. MATERIALS AND METHODS: For measuring DNA damage we performed γH2AX foci microscopy in peripheral blood mononuclear cells (PBMC) after exposure to reduced and conventional absorbed radiation doses using 3rd generation dual-source CT (DSCT) technology...
2016: European Journal of Radiology Open
Yi-Shan Tsai, Yi-Sheng Liu, Yu-Hsiang Shih, Ming-Tsung Chuang, Yuh-Jyh Lin, Chyi-Her Lin, Yung-Chieh Lin
PURPOSE: This study aimed to validate standard deviations of lung densities obtained using high-pitch dual-source computed tomography (DSCT) densitometry as indices of bronchopulmonary dysplasia (BPD) severity in premature infants. METHODS: Data of preterm, late preterm group, and early term groups were evaluated. Mean and median standard deviations (SDmean, SDmedian) of CT lung density (CTLD) were calculated from CT images. RESULTS: SDmean of CTLD in infants with severe BPD was significantly higher than that of infants without BPD (198...
July 2016: Clinical Imaging
Wen-Guang Wang, Yong-Feng He, Yuan-Li Chen, Fu-Mei Zhao, Yan-Qiu Song, Hong Zhang, Yan-He Ma, Xin Guan, Wen-Ya Zhang, Xiao-Lin Chen, Chao Liu, Hong-Liang Cong
OBJECTIVE: To investigate the possible association between plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) and the incidence and severity of calcific aortic valve disease (CAVD). METHODS: This prospective, cross sectional study involved patients with and without (controls) aortic valve calcification diagnosed by transthoracic echocardiography and dual source computed tomography (DSCT) scan. Aortic valves calcification scores were calculated from DSCT scans and patients were graded: grade 1, no calcification; grade 2, mildly calcified; grade 3, moderately calcified; grade 4, heavily calcified...
August 2016: Journal of International Medical Research
Jingjing Hu, Xing Zhao
X-ray dual spectral CT (DSCT) scans the measured object with two different x-ray spectra, and the acquired rawdata can be used to perform the material decomposition of the object. Direct calibration methods allow a faster material decomposition for DSCT and can be separated in two groups: image-based and rawdata-based. The image-based method is an approximative method, and beam hardening artifacts remain in the resulting material-selective images. The rawdata-based method generally obtains better image quality than the image-based method, but this method requires geometrically consistent rawdata...
March 17, 2016: Journal of X-ray Science and Technology
Carlo N De Cecco, Giuseppe Muscogiuri, U Joseph Schoepf, Damiano Caruso, Julian L Wichmann, Paola M Cannaò, Christian Canstein, Stephen R Fuller, Lauren Snider, Akos Varga-Szemes, Andrew D Hardie
OBJECTIVES: To compare image quality and diagnostic accuracy for the detection of liver lesions of virtual unenhanced (VU) images based on third-generation dual-source dual- energy computed tomography (DECT) compared to conventional unenhanced (CU) images. METHODS: Thirty patients underwent triphasic abdominal CT consisting of single-energy CU (120kV, 147 ref.mAs) and dual-energy CT arterial and portal-venous phase acquisitions (100/Sn150kV, 180/90 ref.mAs). VU images were generated from arterial (AVU) and portal venous (PVU) phases...
July 2016: European Journal of Radiology
Jing Chen, Zhi-Gang Yang, Hua-Yan Xu, Ke Shi, Qi-Hua Long, Ying-Kun Guo
OBJECTIVES: To provide a road map of pulmonary vein (PV) and left atrial (LA) variants in patients with atrial fibrillation (AF) before catheter ablation procedure using cardiac CT. METHODS: Cardiac CT was performed in 1420 subjects for accurate anatomical information, including 710 patients with AF and 710 matched controls without AF. PV variants, PV ostia and spatial orientation, LA enlargement, and left atrial diverticulum (LAD) were measured, respectively. Differences between these two groups were also respectively compared...
May 26, 2016: European Radiology
Julian L Wichmann, Andrew D Hardie, U Joseph Schoepf, Lloyd M Felmly, Jonathan D Perry, Akos Varga-Szemes, Stefanie Mangold, Damiano Caruso, Christian Canstein, Thomas J Vogl, Carlo N De Cecco
OBJECTIVES: To compare single-energy (SECT) and dual-energy (DECT) abdominal CT examinations in matched patient cohorts regarding differences in radiation dose and image quality performed with second- and third-generation dual-source CT (DSCT). METHODS: We retrospectively analysed 200 patients (100 male, 100 female; mean age 61.2 ± 13.5 years, mean body mass index 27.5 ± 3.8 kg/m(2)) equally divided into four groups matched by gender and body mass index, who had undergone portal venous phase abdominal CT with second-generation (group A, 120-kV-SECT; group B, 80/140-kV-DECT) and third-generation DSCT (group C, 100-kV-SECT; group D, 90/150-kV-DECT)...
May 10, 2016: European Radiology
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