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https://www.readbyqxmd.com/read/29044366/sustainable-food-systems-for-optimal-planetary-health
#1
Chelsey R Canavan, Ramadhani A Noor, Christopher D Golden, Calestous Juma, Wafaie Fawzi
Sustainable food systems are an important component of a planetary health strategy to reduce the threat of infectious disease, minimize environmental footprint and promote nutrition. Human population trends and dietary transition have led to growing demand for food and increasing production and consumption of meat, amid declining availability of arable land and water. The intensification of livestock production has serious environmental and infectious disease impacts. Land clearing for agriculture alters ecosystems, increases human-wildlife interactions and leads to disease proliferation...
June 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29040959/marantodes-pumilum-kacip-fatimah-enhances-in-vitro-glucose-uptake-in-3t3-l1-adipocyte-cells-and-reduces-pancreatic-complications-in-streptozotocin-nicotinamide-induced-male-diabetic-rats
#2
Siti Hajar Adam, Nelli Giribabu, Noor Mazuin Abu Bakar, Naguib Salleh
Marontades pumilum is claimed to have beneficial effects in the treatment of diabetes mellitus (DM), however the underlying mechanisms were not fully identified. In this study, we hypothesized that M. pumilum could help to enhance cellular glucose uptake and reduces pancreatic complications, which contributed towards its beneficial effects in DM. METHODS: Two parameters were measured (i) rate of glucose uptake by 3T3-L1 adipocyte cells in-vitro (ii) degree of pancreatic destruction in streptozotocin-nicotinamide induced male diabetic rats receiving M...
October 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29039619/evaluation-of-corrosion-behavior-in-artificial-saliva-of-2507-and-2205-duplex-stainless-steel-for-orthodontic-wires-before-and-after-heat-treatment
#3
Ali Sabea Hammood, Ahmed Faraj Noor, Mohammed Talib Alkhafagy
The present study investigates comparison between corrosion behavior of 2507 and 2205 DSS in artificial saliva for orthodontic wires. The heat treatment is necessary for 2507 and 2205 duplex stainless steel to remove or dissolve intermetallic phases, removed segregation and to relieve any residual thermal stress in DSS which may be formed during production processes. The corrosion behavior of a 2507 and 2205 DSS in artificial saliva was studied by SEM, HV test and potentiodynamic measurements. The results indicate that the corrosion resistance mainly depends on presence of secondary phases (sigma phase) and ferrite /austenite ratio, it's revealed that the corrosion resistance of 2507 DSS higher than 2205 DSS in artificial saliva at 37 °C...
October 17, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/29038806/kinetics-of-volatile-impurity-removal-from-silicon-by-electron-beam-melting-for-photovoltaic-applications
#4
Shuang Shi, Pengting Li, Jianxiong Meng, Dachuan Jiang, Yi Tan, H M Noor Ul Huda Khan Asghar
A full domain control model is established for impurity transportation in the liquid phase, gas-liquid interface and gas phase of silicon to analyze the dynamic mechanics of impurity removal. The results show that the overall mass transfer coefficient mainly depends on the temperature and the chamber pressure. Its value increases with the increase of temperature or the decrease of chamber pressure. Under the same melting condition, the order of the overall mass transfer coefficients for P, Al and Ca is kP > kAl > kCa, indicating that P is easier to remove by evaporation...
October 17, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29038699/the-correlation-of-social-support-with-mental-health-a-meta-analysis
#5
Tayebeh Fasihi Harandi, Maryam Mohammad Taghinasab, Tayebeh Dehghan Nayeri
BACKGROUND AND AIM: Social support is an important factor that can affect mental health. In recent decades, many studies have been done on the impact of social support on mental health. The purpose of the present study is to investigate the effect size of the relationship between social support and mental health in studies in Iran. METHODS: This meta-analysis was carried out in studies that were performed from 1996 through 2015. Databases included SID and Magiran, the comprehensive portal of human sciences, Noor specialized magazine databases, IRANDOC, Proquest, PubMed, Scopus, ERIC, Iranmedex and Google Scholar...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29036814/curcumin-ameliorates-neuroinflammation-neurodegeneration-and-memory-deficits-in-p25-transgenic-mouse-model-that-bears-hallmarks-of-alzheimer-s-disease
#6
Jeyapriya Raja Sundaram, Charlene Priscilla Poore, Noor Hazim Bin Sulaimee, Tej Pareek, Wei Fun Cheong, Markus R Wenk, Harish C Pant, Sally A Frautschy, Chian-Ming Low, Sashi Kesavapany
Several studies have indicated that neuroinflammation is indeed associated with neurodegenerative disease pathology. However, failures of recent clinical trials of anti-inflammatory agents in neurodegenerative disorders have emphasized the need to better understand the complexity of the neuroinflammatory process in order to unravel its link with neurodegeneration. Deregulation of Cyclin-dependent kinase 5 (Cdk5) activity by production of its hyperactivator p25 is involved in the formation of tau and amyloid pathology reminiscent of Alzheimer's disease (AD)...
October 12, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29031235/homeobox-genes-and-tooth-development-understanding-the-biological-pathways-and-applications-in-regenerative-dental-science
#7
REVIEW
Anand Ramanathan, Thekkeparambil Chandrabose Srijaya, Prema Sukumaran, Rosnah Binti Zain, Noor Hayaty Abu Kasim
OBJECTIVES: Homeobox genes are a group of conserved class of transcription factors that function as key regulators during the embryonic developmental processes. They act as master regulator for developmental genes, which involves coordinated actions of various auto and cross-regulatory mechanisms. In this review, we summarize the expression pattern of homeobox genes in relation to the tooth development and various signaling pathways or molecules contributing to the specific actions of these genes in the regulation of odontogenesis...
October 4, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29031233/forensic-and-clinical-significance-of-serum-amylase-lipase-and-gamma-glutamyl-transferase-as-predictors-of-outcome-in-head-injured-patients
#8
Mona Mohamed Abo El-Noor, Naema Mahmoud ElHosary, Hytham Ibrahim Elatrozy, Hussein Mohamed Abou Elgheit, Ahmed Mohamed Elbelkasy, Ahmed Gamal Fath, Ghada Hamed El-Shafy
Head trauma is one of the leading causes of death and disability worldwide. Combined head lesions consist of more than one form of lesions. Biochemical markers of brain injury are used in determining the extent of brain injury and predicting its outcomes. The aim of this study was to investigate the forensic and clinical significance of serum amylase, lipase and gamma glutamyl transferase (GGT) as predictors of the outcome in head injured patients. PATIENTS AND METHODS: Sixty head injured patients were enrolled and subjected to personal history taking, general and local physical examination...
October 4, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29027248/ursodeoxycholic-acid-protects-cardiomyocytes-against-cobalt-chloride-induced-hypoxia-by-regulating-transcriptional-mediator-of-cells-stress-hypoxia-inducible-factor-1%C3%AE-and-p53-protein
#9
Anis Syamimi Mohamed, Noorul Izzati Hanafi, Siti Hamimah Sheikh Abdul Kadir, Julina Md Noor, Narimah Abdul Hamid Hasani, Sharaniza Ab Rahim, Rosfaiizah Siran
In hepatocytes, ursodeoxycholic acid (UDCA) activates cell signalling pathways such as p53, intracellular calcium ([Ca(2+) ]i ), and sphingosine-1-phosphate (S1P)-receptor via Gαi -coupled-receptor. Recently, UDCA has been shown to protect the heart against hypoxia-reoxygenation injury. However, it is not clear whether UDCA cardioprotection against hypoxia acts through a transcriptional mediator of cells stress, HIF-1α and p53. Therefore, in here, we aimed to investigate whether UDCA could protect cardiomyocytes (CMs) against hypoxia by regulating expression of HIF-1α, p53, [Ca(2+) ]i , and S1P-Gαi -coupled-receptor...
October 12, 2017: Cell Biochemistry and Function
https://www.readbyqxmd.com/read/29026740/diabetes-and-ramadan-a-concise-and-practical-update
#10
REVIEW
Mohamed H Ahmed, Nazik Elmalaika Husain, Wadie M Elmadhoun, Sufian K Noor, Abbas A Khalil, Ahmed O Almobarak
Despite the fact that the month of Ramadan includes 29-30 days and the duration of fasting for each day can last for between 12 and 16 h, it was estimated that a large number of individuals with diabetes do fast during Ramadan. In light of recent advancement of new pharmacological agents, drugs such as vildagliptin, sitagliptin, and liraglutide were found to be safe to use during this month of fasting. These therapeutic agents can also be used in combination with metformin. The use of sulfonylureas, in most of the recent guidelines about diabetes and Ramadan, seems not to gain much support due to the risk of hypoglycemia...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29024998/response-to-serious-danger-signals-response-to-the-effect-of-neonatal-vitamin-a-supplementation-on-morbidity-and-mortality-at-12%C3%A2-months-a-randomized-trial
#11
Emily R Smith, Alfa Muhihi, Salum Mshamu, Christopher R Sudfeld, Ramadhani Abdallah Noor, Donna Spiegelman, Roger L Shapiro, Honorati Masanja, Wafaie Fawzi
No abstract text is available yet for this article.
September 7, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29024296/evolving-accelerated-amidation-by-spytag-spycatcher-to-analyze-membrane-dynamics
#12
Anthony Howard Keeble, Anusuya Banerjee, Samuel C Reddington, Matteo Paolo Ferla, Mark Howarth, Irsyad Noor Abadi Khairil Anuar
SpyTag is a peptide that forms a spontaneous amide bond with its protein partner SpyCatcher. This protein superglue is a broadly useful tool for molecular assembly, locking together biological building blocks efficiently and irreversibly in diverse architectures. We initially developed SpyTag and SpyCatcher by rational design, through splitting a domain from a Gram-positive bacterial adhesin. Here we establish a phage display platform able to select for specific amidation, achieving an order of magnitude acceleration for interaction of the SpyTag002 variant with the SpyCatcher002 variant...
October 10, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29023266/novel-zbtb24-mutation-associated-with-immunodeficiency-centromere-instability-and-facial-anomalies-type-2-syndrome-identified-in-a-patient-with-very-early-onset-inflammatory-bowel-disease
#13
Máire A Conrad, Noor Dawany, Kathleen E Sullivan, Marcella Devoto, Judith R Kelsen
BACKGROUND: Very early onset inflammatory bowel disease, diagnosed in children ≤5 years old, can be the initial presentation of some primary immunodeficiencies. METHODS: In this study, we describe a 17-month-old boy with recurrent infections, growth failure, facial anomalies, and inflammatory bowel disease. Immune evaluation, whole-exome sequencing, karyotyping, and methylation array were performed to evaluate the child's constellation of symptoms and examination findings...
October 11, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29023076/flavonoid-production-growth-and-differentiation-of-stelechocarpus-burahol-bl-hook-f-and-th-cell-suspension-culture
#14
Noor Aini Habibah, Sukarti Moeljopawiro, Kumala Dewi, Ari Indrianto
BACKGROUND AND OBJECTIVE: Stelechocarpus burahol is a plant containing flavonoid compounds that have the potential for use as an antihyperuricemic for gout medication. This study was performed to assess flavonoid production, growth and cell differentiation of S. burahol in cell suspension culture. METHODOLOGY: Mesocarp was planted in Murashige and Skoog (MS) medium supplemented with 7.5 mg L-1 picloram for the induction of callus. Non-embryonic callus obtained was used in the formation of cell suspension cultures...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/29022837/critical-parameters-for-particle-based-pulmonary-delivery-of-chemotherapeutics
#15
Ali Dabbagh, Noor Hayaty Abu Kasim, Chai Hong Yeong, Tin Wui Wong, Noorsaadah Abdul Rahman
Targeted delivery of chemotherapeutics through the respiratory system is a potential approach to improve drug accumulation in the lung tumor, while decreasing their negative side effects. However, elimination by the pulmonary clearance mechanisms, including the mucociliary transport system, and ingestion by the alveolar macrophages, rapid absorption into the blood, enzymatic degradation, and low control over the deposition rate and location remain the main complications for achieving an effective pulmonary drug delivery...
October 12, 2017: Journal of Aerosol Medicine and Pulmonary Drug Delivery
https://www.readbyqxmd.com/read/29022146/cupriavidus-malaysiensis-sp-nov-a-novel-poly-3-hydroxybutyrate-co-4-hydroxybutyrate-accumulating-bacterium-isolated-from-the-malaysian-environment
#16
Hema Ramachandran, Nur Asilla Hani Shafie, Kumar Sudesh, Mohamad Noor Azizan, Mohamad Isa Abdul Majid, Al-Ashraf Abdullah Amirul
Bacterial classification on the basis of a polyphasic approach was conducted on three poly(3 hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] accumulating bacterial strains that were isolated from samples collected from Malaysian environments; Kulim Lake, Sg. Pinang river and Sg. Manik paddy field. The Gram-negative, rod-shaped, motile, non-sporulating and non-fermenting bacteria were shown to belong to the genus Cupriavidus of the Betaproteobacteria on the basis of their 16S rRNA gene sequence analyses...
October 11, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29019978/the-prevalence-of-plasmodium-falciparum-in-sub-saharan-africa-since-1900
#17
Robert W Snow, Benn Sartorius, David Kyalo, Joseph Maina, Punam Amratia, Clara W Mundia, Philip Bejon, Abdisalan M Noor
Malaria transmission is influenced by climate, land use and deliberate interventions. Recent declines have been observed in malaria transmission. Here we show that the African continent has witnessed a long-term decline in the prevalence of Plasmodium falciparum from 40% prevalence in the period 1900-1929 to 24% prevalence in the period 2010-2015, a trend that has been interrupted by periods of rapidly increasing or decreasing transmission. The cycles and trend over the past 115 years are inconsistent with explanations in terms of climate or deliberate intervention alone...
October 11, 2017: Nature
https://www.readbyqxmd.com/read/29016635/hiv-human-herpesvirus-co-infections-impact-on-tryptophan-kynurenine-pathway-and-immune-reconstitution
#18
Siew Hwei Yap, Noor Kamila Abdullah, Megan McStea, Kozo Takayama, Meng Li Chong, Elisa Crisci, Marie Larsson, Iskandar Azwa, Adeeba Kamarulzaman, Kok Hoong Leong, Yin Ling Woo, Reena Rajasuriar
BACKGROUND: Co-infections with human herpesvirus (HHV) have been associated with residual chronic inflammation in antiretroviral (ART)-treated human immunodeficiency virus (HIV)-infected individuals. However, the role of HHV in modulating the tryptophan-kynurenine pathway and clinical outcomes in HIV-infected individuals is poorly understood. Thus, we investigated the seroprevalence of four common HHVs among treated HIV-infected participants and their impact on kynurenine/tryptophan (K/T) ratio and long-term CD4 T-cell recovery in HIV/HHV co-infected participants...
2017: PloS One
https://www.readbyqxmd.com/read/28993736/pathogenic-mechanisms-of-bicuspid-aortic-valve-aortopathy
#19
REVIEW
Noor M Yassine, Jasmine T Shahram, Simon C Body
Bicuspid aortic valve (BAV) is the most common congenital valvular defect and is associated with ascending aortic dilation (AAD) in a quarter of patients. AAD has been ascribed both to the hemodynamic consequences of normally functioning and abnormal BAV morphology, and to the effect of rare and common genetic variation upon function of the ascending aortic media. AAD manifests in two overall and sometimes overlapping phenotypes: that of aortic root aneurysm, similar to the AAD of Marfan syndrome; and that of tubular AAD, similar to the AAD seen with tricuspid aortic valves (TAVs)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28993680/rheumatoid-arthritis-and-risk-for-alzheimer-s-disease-a-systematic-review-and-meta-analysis-and-a-mendelian-randomization-study
#20
Stefania Policicchio, Aminah Noor Ahmad, John Francis Powell, Petroula Proitsi
Rheumatoid arthritis (RA) patients have been observed to be at a lower risk of developing Alzheimer's Disease (AD). Clinical trials have showed no relationship between nonsteroidal anti-inflammatory drug (NSAID) use and AD. The aim of this study was to establish if there is a causal link between RA and AD. A systematic literature review on RA incidence and its link to AD was carried out according to the PRISMA guidelines. Eight case-control and two population-based studies were included in a random effects meta-analysis...
October 9, 2017: Scientific Reports
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