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Mike English

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https://www.readbyqxmd.com/read/29651981/lamotrigine-for-people-with-borderline-personality-disorder-a-rct
#1
Mike J Crawford, Rahil Sanatinia, Barbara Barrett, Gillian Cunningham, Oliver Dale, Poushali Ganguli, Geoff Lawrence-Smith, Verity C Leeson, Fenella Lemonsky, Georgia Lykomitrou-Matthews, Alan Montgomery, Richard Morriss, Jasna Munjiza, Carol Paton, Iwona Skorodzien, Vineet Singh, Wei Tan, Peter Tyrer, Joseph G Reilly
BACKGROUND: No drug treatments are currently licensed for the treatment of borderline personality disorder (BPD). Despite this, people with this condition are frequently prescribed psychotropic medications and often with considerable polypharmacy. Preliminary studies have indicated that mood stabilisers may be of benefit to people with BPD. OBJECTIVE: To examine the clinical effectiveness and cost-effectiveness of lamotrigine for people with BPD. DESIGN: A two-arm, double-blind, placebo-controlled individually randomised trial of lamotrigine versus placebo...
April 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29616146/expectations-for-nursing-care-in-newborn-units-in-kenya-moving-from-implicit-to-explicit-standards
#2
REVIEW
Georgina A V Murphy, Gregory B Omondi, David Gathara, Nancy Abuya, Jacintah Mwachiro, Rose Kuria, Edna Tallam-Kimaiyo, Mike English
Neonatal mortality currently accounts for 45% of all child mortality in Kenya, standing at 22 per 1000 live births. Access to basic but high quality inpatient neonatal services for small and sick newborns will be key in reducing neonatal mortality. Neonatal inpatient care is reliant on nursing care, yet explicit nursing standards for such care do not currently exist in Kenya. We reviewed the Nursing Council of Kenya 'Manual of Clinical Procedures' to identify tasks relevant for the care of inpatient neonates...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29526390/promoting-men-s-knowledge-of-cancer-risk-reduction-a-systematic-review-of-interventions
#3
REVIEW
Mary Reidy, Mohamad M Saab, Josephine Hegarty, Christian Von Wagner, Mairin O'Mahony, Mike Murphy, Frances J Drummond
OBJECTIVE: To critically appraise and discuss evidence from interventions designed to increase men's knowledge about cancer risk reduction. METHODS: A systematic review was conducted. Six electronic databases were searched for interventions published between January 1st 2006 and May 30th 2016 in English. Studies were included if they used an experimental design, included adult males (≥18 years), and had a primary focus on the acquisition and utilisation of information on cancer risk reduction...
March 3, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29514814/approaching-quality-improvement-at-scale-a-learning-health-system-approach-in-kenya
#4
Grace Irimu, Morris Ogero, George Mbevi, Ambrose Agweyu, Samuel Akech, Thomas Julius, Rachel Nyamai, David Githang'a, Philip Ayieko, Mike English
No abstract text is available yet for this article.
March 7, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29497504/an-observational-study-of-monitoring-of-vital-signs-in-children-admitted-to-kenyan-hospitals-an-insight-into-the-quality-of-nursing-care
#5
Morris Ogero, Philip Ayieko, Boniface Makone, Thomas Julius, Lucas Malla, Jacquie Oliwa, Grace Irimu, Mike English
Background: Measurement and correct interpretation of vital signs is part of routine clinical care. Repeated measurement enhances early recognition of deterioration, may help prevent morbidity and mortality and is a standard of care in most countries. Objective: To examine documentation of vital signs by clinicians for admissions to paediatric wards in Kenyan hospitals, to describe monitoring frequency by nurses and explore factors influencing frequency. Methods: Vital signs information (temperature, respiratory and pulse rate) for the first 48 hours of admission was collected from case records of children admitted with non-surgical conditions to 13 Kenyan county hospitals between September 2013 and April 2016...
June 2018: Journal of Global Health
https://www.readbyqxmd.com/read/29495961/hospital-mortality-a-neglected-but-rich-source-of-information-supporting-the-transition-to-higher-quality-health-systems-in-low-and-middle-income-countries
#6
Mike English, Paul Mwaniki, Thomas Julius, Mercy Chepkirui, David Gathara, Paul O Ouma, Peter Cherutich, Emelda A Okiro, Robert W Snow
BACKGROUND: There is increasing focus on the strength of primary health care systems in low and middle-income countries (LMIC). There are important roles for higher quality district hospital care within these systems. These hospitals are also sources of information of considerable importance to health systems, but this role, as with the wider roles of district hospitals, has been neglected. KEY MESSAGES: As we make efforts to develop higher quality health systems in LMIC we highlight the critical importance of district hospitals focusing here on how data on hospital mortality offers value: i) in understanding disease burden; ii) as part of surveillance and impact monitoring; iii) as an entry point to exploring system failures; and iv) as a lens to examine variability in health system performance and possibly as a measure of health system quality in its own right...
March 1, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29490058/potential-for-reducing-inappropriate-antibiotic-prescribing-in-english-primary-care
#7
Timo Smieszek, Koen B Pouwels, F Christiaan K Dolk, David R M Smith, Susan Hopkins, Mike Sharland, Alastair D Hay, Michael V Moore, Julie V Robotham
Objectives: To identify and quantify inappropriate systemic antibiotic prescribing in primary care in England, and ultimately to determine the potential for reduction in prescribing of antibiotics. Methods: Primary care data from 2013-15 recorded in The Health Improvement Network (THIN) database were used. Potentially inappropriate prescribing events in the database were identified by: (i) comparing prescribing events against treatment guidelines; (ii) comparing actual proportions of consultations resulting in prescription for a set of conditions with the ideal proportions derived from expert opinion; and (iii) identifying high prescribers and their number of prescriptions above an age- and body-system-specific benchmark...
February 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29453812/cognitive-outcomes-in-children-and-adolescents-born-very-preterm-a-meta-analysis
#8
REVIEW
Christopher R Brydges, Jasmin K Landes, Corinne L Reid, Catherine Campbell, Noel French, Mike Anderson
AIM: To estimate the association between very preterm birth (<32wks' gestation) and intelligence, executive functioning, and processing speed throughout childhood and adolescence, and to examine the effects of gestational age, birthweight, and age at assessment. METHOD: Studies were included if children were born at earlier than 32 weeks' gestation, aged 4 to 17 years, had an age-matched term control group, and if the studies used standardized measures, were published in an English-language peer-reviewed journal, and placed no restrictions on participants based on task performance...
February 17, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29447483/the-art-of-recovery-outcomes-from-participatory-arts-activities-for-people-using-mental-health-services
#9
Theodore Stickley, Nicola Wright, Mike Slade
BACKGROUND: There is a growing evidence base for the use of participatory arts for the purposes of health promotion. In recent years, recovery approaches in mental healthcare have become commonplace in English speaking countries amongst others. There are few studies that bring together these two fields of practice. AIMS: The two aims of this study were (a) to investigate the validity of the CHIME framework for characterising the experience of Participatory Arts and (b) to use the CHIME framework to investigate the relationship between participatory arts and mental health recovery...
February 15, 2018: Journal of Mental Health
https://www.readbyqxmd.com/read/29440153/does-assistive-technology-contribute-to-social-inclusion-for-people-with-intellectual-disability-a-systematic-review-protocol
#10
John Owuor, Fiona Larkan, Bonnix Kayabu, Geraldine Fitzgerald, Greg Sheaf, John Dinsmore, Roy McConkey, Mike Clarke, Malcolm MacLachlan
INTRODUCTION: The aim of this review is to answer the following question: Does assistive technology contribute to social inclusion for people with intellectual disability? Previous research on assistive technology has focused on socioeconomic impacts such as education, employment and access to healthcare by people with intellectual disability. There is a need to consolidate evidence on the interaction between intellectual disability, assistive technology, community living and social inclusion...
February 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29431016/assessment-and-management-of-constipation-for-patients-receiving-palliative-care-in-specialist-palliative-care-settings-a-systematic-review-of-the-literature
#11
Deborah Hl Muldrew, Felicity Hasson, Emma Carduff, Mike Clarke, Jo Coast, Anne Finucane, Lisa Graham, Philip Larkin, Noleen K McCorry, Paul Slater, Max Watson, Eileen Wright, Sonja McIlfatrick
BACKGROUND: Constipation is an important issue for patients receiving palliative care within specialist palliative care settings. Questions and ambiguity, however, persist about international best practice and management. AIM: To synthesise the current evidence base on the assessment and management of constipation for palliative care patients within a specialist palliative care setting. DESIGN: This is a systematic review. DATA SOURCES: MEDLINE, Embase, CINAHL, Scopus and Cochrane databases were systematically searched in April 2017 for empirical studies, written in English, on the assessment and management of constipation in specialist palliative care settings, published between 2007 and 2017...
February 1, 2018: Palliative Medicine
https://www.readbyqxmd.com/read/29419624/intermittent-fasting-interventions-for-treatment-of-overweight-and-obesity-in-adults-a-systematic-review-and-meta-analysis
#12
Leanne Harris, Sharon Hamilton, Liane B Azevedo, Joan Olajide, Caroline De Brún, Gillian Waller, Vicki Whittaker, Tracey Sharp, Mike Lean, Catherine Hankey, Louisa Ells
OBJECTIVE: To examine the effectiveness of intermittent energy restriction in the treatment for overweight and obesity in adults, when compared to usual care treatment or no treatment. INTRODUCTION: Intermittent energy restriction encompasses dietary approaches including intermittent fasting, alternate day fasting, and fasting for two days per week. Despite the recent popularity of intermittent energy restriction and associated weight loss claims, the supporting evidence base is limited...
February 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29396220/access-to-emergency-hospital-care-provided-by-the-public-sector-in-sub-saharan-africa-in-2015-a-geocoded-inventory-and-spatial-analysis
#13
Paul O Ouma, Joseph Maina, Pamela N Thuranira, Peter M Macharia, Victor A Alegana, Mike English, Emelda A Okiro, Robert W Snow
BACKGROUND: Timely access to emergency care can substantially reduce mortality. International benchmarks for access to emergency hospital care have been established to guide ambitions for universal health care by 2030. However, no Pan-African database of where hospitals are located exists; therefore, we aimed to complete a geocoded inventory of hospital services in Africa in relation to how populations might access these services in 2015, with focus on women of child bearing age. METHODS: We assembled a geocoded inventory of public hospitals across 48 countries and islands of sub-Saharan Africa, including Zanzibar, using data from various sources...
January 25, 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29389541/association-of-the-paediatric-admission-quality-of-care-score-with-mortality-in-kenyan-hospitals-a-validation-study
#14
Charles Opondo, Elizabeth Allen, Jim Todd, Mike English
BACKGROUND: Measuring the quality of hospital admission care is essential to ensure that standards of practice are met and continuously improved to reduce morbidity and mortality associated with the illnesses most responsible for inpatient deaths. The Paediatric Admission Quality of Care (PAQC) score is a tool for measuring adherence to guidelines for children admitted with acute illnesses in a low-income setting. We aimed to explore the external and criterion-related validity of the PAQC score by investigating its association with mortality using data drawn from a diverse sample of Kenyan hospitals...
February 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29370845/quality-improvement-initiatives-for-hospitalised-small-and-sick-newborns-in-low-and-middle-income-countries-a-systematic-review
#15
REVIEW
Nabila Zaka, Emma C Alexander, Logan Manikam, Irena C F Norman, Melika Akhbari, Sarah Moxon, Pavani Kalluri Ram, Georgina Murphy, Mike English, Susan Niermeyer, Luwei Pearson
BACKGROUND: An estimated 2.6 million newborns died in 2016; over 98.5% of deaths occurred in low- and middle-income countries (LMICs). Neonates born preterm and small for gestational age are particularly at risk given the high incidence of infectious complications, cardiopulmonary, and neurodevelopmental disorders in this group. Quality improvement (QI) initiatives can reduce the burden of mortality and morbidity for hospitalised newborns in these settings. We undertook a systematic review to synthesise evidence from LMICs on QI approaches used, outcome measures employed to estimate effects, and the nature of implementation challenges...
January 25, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29329448/the-prevalence-and-management-of-dehydration-amongst-neonatal-admissions-to-general-paediatric-wards-in-kenya-a-clinical-audit
#16
Samuel Akech, Beatrice Rotich, Mercy Chepkirui, Philip Ayieko, Grace Irimu, Mike English
An audit of randomly selected case records of 810 patients admitted to 13 hospitals between December 2015 and November 2016 was done. Prevalence of dehydration was 19.7% (2293 of 11 636) [95% CI: 17.1-22.6%], range across hospitals was 9.4% to 27.0%. Most cases with dehydration were clinically diagnosed (82 of 153; 53.6%), followed by excessive weight loss (54 of 153; 35.3%) and abnormal urea/electrolytes/creatinine (23 of 153; 15.0%). Documentation of fluids prescribed was poor but, where data were available, Ringers lactate (30 of 153; 19...
January 9, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29241618/appropriateness-of-clinical-severity-classification-of-new-who-childhood-pneumonia-guidance-a-multi-hospital-retrospective-cohort-study
#17
MULTICENTER STUDY
Ambrose Agweyu, Richard J Lilford, Mike English
BACKGROUND: Management of pneumonia in many low-income and middle-income countries is based on WHO guidelines that classify children according to clinical signs that define thresholds of risk. We aimed to establish whether some children categorised as eligible for outpatient treatment might have a risk of death warranting their treatment in hospital. METHODS: We did a retrospective cohort study of children aged 2-59 months admitted to one of 14 hospitals in Kenya with pneumonia between March 1, 2014, and Feb 29, 2016, before revised WHO pneumonia guidelines were adopted in the country...
January 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29229656/informing-future-research-for-carriage-of-multiresistant-gram-negative-bacteria-problems-with-recruiting-to-an-english-stool-sample-community-prevalence-study
#18
Donna M Lecky, Deborah Nakiboneka-Ssenabulya, Tom Nichols, Peter Hawkey, Kim Turner, Keun-Taik Chung, Mike Thomas, Helen Lucy Thomas, Li Xu McCrae, Sahida Shabir, Susan Manzoor, Adela Alvarez-Buylla, Steve Smith, Cliodna McNulty
OBJECTIVES: This study aims to highlight problems with recruiting to an English stool sample community prevalence study. It was part of a larger cross-sectional research to determine the risk factors for the presence of extended-spectrum beta-lactamase and carbapenemase-producing coliforms in stool samples of the asymptomatic general English population. SETTING: Four National Health Service primary care trusts (PCTs) of England representing a different section of the population of England: Newham PCT; Heart of Birmingham Teaching PCT; Shropshire County PCT; and Southampton City PCT...
December 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/29212522/a-systematic-review-of-neonatal-treatment-intensity-scores-and-their-potential-application-in-low-resource-setting-hospitals-for-predicting-mortality-morbidity-and-estimating-resource-use
#19
Jalemba Aluvaala, Gary S Collins, Michuki Maina, James A Berkley, Mike English
BACKGROUND: Treatment intensity scores can predict mortality and estimate resource use. They may therefore be of interest for essential neonatal care in low resource settings where neonatal mortality remains high. We sought to systematically review neonatal treatment intensity scores to (1) assess the level of evidence on predictive performance in predicting clinical outcomes and estimating resource utilisation and (2) assess the applicability of the identified models to decision making for neonatal care in low resource settings...
December 7, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29207988/correction-to-an-exploration-of-mortality-risk-factors-in-non-severe-pneumonia-in-children-using-clinical-data-from-kenya
#20
Timothy Tuti, Ambrose Agweyu, Paul Mwaniki, Niels Peek, Mike English
The original article contains an omission in the Acknowledgements sub-section of the Declarations.
December 5, 2017: BMC Medicine
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