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Mike English

Beatrice I Amboko, Philip Ayieko, Morris Ogero, Thomas Julius, Grace Irimu, Mike English
BACKGROUND: Up to 90 % of the global burden of malaria morbidity and mortality occurs in sub-Saharan Africa and children under-five bear a disproportionately high malaria burden. Effective inpatient case management can reduce severe malaria mortality and morbidity, but there are few reports of how successfully international and national recommendations are adopted in management of inpatient childhood malaria. METHODS: A descriptive cross-sectional study of inpatient malaria case management practices was conducted using data collected over 24 months in five hospitals from high malaria risk areas participating in the Clinical Information Network (CIN) in Kenya...
October 18, 2016: Malaria Journal
Edwine W Barasa, Susan Cleary, Mike English, Sassy Molyneux
BACKGROUND: Priority setting and resource allocation in healthcare organizations often involves the balancing of competing interests and values in the context of hierarchical and politically complex settings with multiple interacting actor relationships. Despite this, few studies have examined the influence of actor and power dynamics on priority setting practices in healthcare organizations. This paper examines the influence of power relations among different actors on the implementation of priority setting and resource allocation processes in public hospitals in Kenya...
September 30, 2016: BMC Health Services Research
Edwine W Barasa, Susan Cleary, Sassy Molyneux, Mike English
This paper describes and evaluates the budgeting and planning processes in public hospitals in Kenya. We used a qualitative case study approach to examine these processes in two hospitals in Kenya. We collected data by in-depth interviews of national level policy makers, hospital managers, and frontline practitioners in the case study hospitals (n = 72), a review of documents, and non-participant observations within the hospitals over a 7 month period. We applied an evaluative framework that considers both consequentialist and proceduralist conditions as important to the quality of priority-setting processes...
September 26, 2016: Health Policy and Planning
Hilary Edgcombe, Chris Paton, Mike English
In this paper, we discuss the role of mobile technology in developing training tools for health workers, with particular reference to low-income countries (LICs). The global and technological context is outlined, followed by a summary of approaches to using and evaluating mobile technology for learning in healthcare. Finally, recommendations are made for those developing and using such tools, based on current literature and the authors' involvement in the field.
September 22, 2016: Archives of Disease in Childhood
Mike S Schäfer, Julia Metag, Jessica Feustle, Livia Herzog
Crowdfunding has emerged as an additional source for financing research in recent years. The study at hand identifies and tests explanatory factors influencing the success of scientific crowdfunding projects by drawing on news value theory, the "reputation signaling" approach, and economic theories of online payment. A standardized content analysis of 371 projects on English- and German-language platforms reveals that each theory provides factors influencing crowdfunding success. It shows that projects presented on science-only crowdfunding platforms have a higher success rate...
September 19, 2016: Public Understanding of Science
Dan Todkill, Helen E Hughes, Alex J Elliot, Roger A Morbey, Obaghe Edeghere, Sally Harcourt, Tom Hughes, Tina Endericks, Brian McCloskey, Mike Catchpole, Sue Ibbotson, Gillian Smith
: Introduction In preparation for the London 2012 Olympic Games, existing syndromic surveillance systems operating in England were expanded to include daily general practitioner (GP) out-of-hours (OOH) contacts and emergency department (ED) attendances at sentinel sites (the GP OOH and ED syndromic surveillance systems: GPOOHS and EDSSS). Hypothesis/Problem The further development of syndromic surveillance systems in time for the London 2012 Olympic Games provided a unique opportunity to investigate the impact of a large mass-gathering event on public health and health services as monitored in near real-time by syndromic surveillance of GP OOH contacts and ED attendances...
September 19, 2016: Prehospital and Disaster Medicine
Mike Friedman, Anne-Laure Bartier, Josh Lown, Christopher J Hopwood
Consumer behavior is driven, in part, by the degree to which goods and services appeal to underlying motives for agency and communion. The purpose of this research was to develop a brief individual differences measure of these motivations for use in behavioral research and theoretical and applied consumer psychology and marketing studies. We employed a bi-lingual scale development procedure to create the 10-item Agentic and Communal Consumer Motivation Inventory (ACCMI) in English and French. Two studies show that the ACCMI is language invariant, demonstrates convergent and discriminant validity with consumer, motivational, and interpersonal constructs, and predicts evaluations of products described in agentic and communal terms, respectively, in both languages...
2016: Frontiers in Psychology
(no author information available yet)
"Universal design provides a blueprint for maximum inclusion of all people" [7]. This statement is now nearly 20 years old. The present collection of papers from the 3rd International Conference on Universal Design (UD 2016) is testament to the fact that Universal Design is now benefitting from a climate that is more knowledgeable about, and possibly more accommodating of, individual differences between people. However, there are still many open issues, and much to be learnt from exchanging experiences between all stakeholders interested in Universal Design, be they policy makers, practitioners or researchers...
2016: Studies in Health Technology and Informatics
Alison M Cogan, Jeanine Blanchard, Susan L Garber, Cheryl Lp Vigen, Mike Carlson, Florence A Clark
OBJECTIVE: To investigate the efficacy of behavioral or educational interventions in preventing pressure ulcers in community-dwelling adults with spinal cord injury (SCI). DATA SOURCES: Cochrane, Clinical Trials, PubMed, and Web of Science were searched in June 2016. The search combined related terms for pressure ulcers, spinal cord injury, and behavioral intervention. Each database was searched from its inception with no restrictions on year of publication. REVIEW METHODS: Inclusion criteria required that articles were (a) published in a peer-reviewed journal in English, (b) evaluated a behavioral or educational intervention for pressure ulcer prevention, (c) included community-dwelling adult participants aged 18 years and older with SCI, (d) measured pressure ulcer occurrence, recurrence, or skin breakdown as an outcome, and (e) had a minimum of 10 participants...
July 20, 2016: Clinical Rehabilitation
Timothy Tuti, Michael Bitok, Lucas Malla, Chris Paton, Naomi Muinga, David Gathara, Susan Gachau, George Mbevi, Wycliffe Nyachiro, Morris Ogero, Thomas Julius, Grace Irimu, Mike English
In many low income countries health information systems are poorly equipped to provide detailed information on hospital care and outcomes. Information is thus rarely used to support practice improvement. We describe efforts to tackle this challenge and to foster learning concerning collection and use of information. This could improve hospital services in Kenya. We are developing a Clinical Information Network, a collaboration spanning 14 hospitals, policy makers and researchers with the goal of improving information available on the quality of inpatient paediatric care across common childhood illnesses in Kenya...
May 24, 2016: BMJ Global Health
Charles Opondo, Elizabeth Allen, Jim Todd, Mike English
BACKGROUND: Evaluating clinician compliance with recommended steps in clinical guidelines provides one measure of quality of process of care but can result in a multiplicity of indicators across illnesses, making it problematic to produce any summative picture of process quality, information that may be most useful to policy-makers and managers. OBJECTIVE: We set out to develop a clinically logical summative measure of the quality of care provided to children admitted to hospital in Kenya spanning the three diagnoses present in 60% or more of admissions that would provide a patient level measure of quality of care in the face of co-morbidity...
July 8, 2016: Tropical Medicine & International Health: TM & IH
Daiana D Becker-Santos, Kelsie L Thu, John C English, Larissa A Pikor, Victor D Martinez, May Zhang, Emily A Vucic, Margaret Ty Luk, Anita Carraro, Jagoda Korbelik, Daniela Piga, Nicolas M Lhomme, Mike J Tsay, John Yee, Calum E MacAulay, Stephen Lam, William W Lockwood, Wendy P Robinson, Igor Jurisica, Wan L Lam
Genes involved in fetal lung development are thought to play crucial roles in the malignant transformation of adult lung cells. Consequently, the study of lung tumour biology in the context of lung development has the potential to reveal key developmentally relevant genes that play critical roles in lung cancer initiation/progression. Here, we describe for the first time a comprehensive characterization of miRNA expression in human fetal lung tissue, with subsequent identification of 37 miRNAs in non-small cell lung cancer (NSCLC) that recapitulate their fetal expression patterns...
October 2016: Journal of Pathology
Elesban Kihuba, Adrian Gheorghe, Fiammetta Bozzani, Mike English, Ulla K Griffiths
BACKGROUND: Low- and middle-income countries need to sustain efficiency and equity in health financing on their way to universal health care coverage. However, systems meant to generate quality economic information are often deficient in such settings. We assessed the feasibility of streamlining cost accounting systems within the Kenyan health sector to illustrate the pragmatic challenges and opportunities. DESIGN: We reviewed policy documents, and conducted field observations and semi-structured interviews with key informants in the health sector...
2016: Global Health Action
Hana Mijovic, Jacob McKnight, Mike English
AIMS AND OBJECTIVES: To review systematically, qualitative literature covering the implementation of task shifting in sub-Saharan Africa to address the growing interest in interventions of this kind. This review aims to distil the key practical findings to both guide a specific project aiming to improve the quality of neonatal care in Kenya and to contribute to the broader literature. BACKGROUND: Task-shifting programmes aim to improve access to healthcare by delegating specific tasks from higher to lower skilled health workers...
August 2016: Journal of Clinical Nursing
Thomas Partridge, Ian Carluke, Kevin Emmerson, Paul Partington, Mike Reed
Patient reported outcome measures (PROMs) were introduced in 2009 to allow patient perspectives to potentially influence change and improvement. In collaboration with the national joint registry (NJR), PROMs data has been examined on a national basis to compare surgical factors in total knee replacement (TKR). Initial results demonstrated there were statistically significant differences in Oxford Knee Score (OKS) when using different brands of implant. Preservation of the infrapatella fatpad (IFP) has also been shown improve outcomes...
2016: BMJ Quality Improvement Reports
Kristin Black, Katherine Miller, Gavin Beck, Michael Moser
INTRODUCTION: The purpose of this study is to determine what information about donation after circulatory death (DCD) is available on the Internet and to document the common statements for and against DCD. METHODS: The search terms non-heart-beating donor, donation after cardiac death, DCD, deceased donor, organ donation, and organ harvesting were entered into the four most-accessed English-language Internet search engines. The top 10 webpages from each search (240 webpages) yielded 116 unique sites...
August 2016: Clinical Transplantation
Gary McLean, Elizabeth Murray, Rebecca Band, Keith R Moffat, Peter Hanlon, Anne Bruton, Mike Thomas, Lucy Yardley, Frances S Mair
BACKGROUND: To identify, summarise and synthesise the evidence for using interactive digital interventions to support patient self-management of asthma, and determine their impact. METHODS: Systematic review with meta-analysis. We searched MEDLINE, EMBASE, CINAHL, PsycINFO, ERIC, Cochrane Library, DoPHER, TROPHI, Social Science Citation Index and Science Citation Index. The selection criteria requirement was studies of adults (16 years and over) with asthma, interventions that were interactive digital interventions and the comparator was usual care...
2016: BMC Pulmonary Medicine
Cassie Aldridge, Julian Bion, Amunpreet Boyal, Yen-Fu Chen, Mike Clancy, Tim Evans, Alan Girling, Joanne Lord, Russell Mannion, Peter Rees, Chris Roseveare, Gavin Rudge, Jianxia Sun, Carolyn Tarrant, Mark Temple, Sam Watson, Richard Lilford
BACKGROUND: Increased mortality rates associated with weekend hospital admission (the so-called weekend effect) have been attributed to suboptimum staffing levels of specialist consultants. However, evidence for a causal association is elusive, and the magnitude of the weekend specialist deficit remains unquantified. This uncertainty could hamper efforts by national health systems to introduce 7 day health services. We aimed to examine preliminary associations between specialist intensity and weekend admission mortality across the English National Health Service...
July 9, 2016: Lancet
Malin Melin, Patricio Rivera, Maja Arendt, Ingegerd Elvers, Eva Murén, Ulla Gustafson, Mike Starkey, Kaja Sverdrup Borge, Frode Lingaas, Jens Häggström, Sara Saellström, Henrik Rönnberg, Kerstin Lindblad-Toh
Canine mammary tumours (CMT) are the most common neoplasia in unspayed female dogs. CMTs are suitable naturally occurring models for human breast cancer and share many characteristics, indicating that the genetic causes could also be shared. We have performed a genome-wide association study (GWAS) in English Springer Spaniel dogs and identified a genome-wide significant locus on chromosome 11 (praw = 5.6x10-7, pperm = 0.019). The most associated haplotype spans a 446 kb region overlapping the CDK5RAP2 gene...
May 2016: PLoS Genetics
Mike English, Grace Irimu, Ambrose Agweyu, David Gathara, Jacquie Oliwa, Philip Ayieko, Fred Were, Chris Paton, Sean Tunis, Christopher B Forrest
Mike English and colleagues argue that as efforts are made towards achieving universal health coverage it is also important to build capacity to develop regionally relevant evidence to improve healthcare.
April 2016: PLoS Medicine
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