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John Brownstein

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https://www.readbyqxmd.com/read/28389417/determinants-of-participants-follow-up-and-characterization-of-representativeness-in-flu-near-you-a-participatory-disease-surveillance-system
#1
Kristin Baltrusaitis, Mauricio Santillana, Adam W Crawley, Rumi Chunara, Mark Smolinski, John S Brownstein
BACKGROUND: Flu Near You (FNY) is an Internet-based participatory surveillance system in the United States and Canada that allows volunteers to report influenza-like symptoms using a brief weekly symptom report. OBJECTIVE: Our objective was to evaluate the representativeness of the FNY population compared with the general population of the United States, explore the demographic and behavioral characteristics associated with FNY's high-participation users, and summarize results from a user survey of a cohort of FNY participants...
April 7, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28346168/vaccine-compliance-and-the-2016-arkansas-mumps-outbreak
#2
Maimuna S Majumder, Colleen M Nguyen, Emily L Cohn, Yulin Hswen, Sumiko R Mekaru, John S Brownstein
No abstract text is available yet for this article.
April 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28166175/using-twitter-to-identify-and-respond-to-food-poisoning-the-food-safety-stl-project
#3
Jenine K Harris, Jared B Hawkins, Leila Nguyen, Elaine O Nsoesie, Gaurav Tuli, Raed Mansour, John S Brownstein
CONTEXT: Foodborne illness affects 1 in 4 US residents each year. Few of those sickened seek medical care or report the illness to public health authorities, complicating prevention efforts. Citizens who report illness identify food establishments with more serious and critical violations than found by regular inspections. New media sources, including online restaurant reviews and social media postings, have the potential to improve reporting. OBJECTIVE: We implemented a Web-based Dashboard (HealthMap Foodborne Dashboard) to identify and respond to tweets about food poisoning from St Louis City residents...
February 3, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28123858/social-media-as-a-sentinel-for-disease-surveillance-what-does-sociodemographic-status-have-to-do-with-it
#4
Elaine O Nsoesie, Luisa Flor, Jared Hawkins, Adyasha Maharana, Tobi Skotnes, Fatima Marinho, John S Brownstein
INTRODUCTION: Data from social media have been shown to have utility in augmenting traditional approaches to public health surveillance. Quantifying the representativeness of these data is needed for making accurate public health inferences. METHODS: We applied machine-learning methods to explore spatial and temporal dengue event reporting trends on Twitter relative to confirmed cases, and quantified associations with sociodemographic factors across three Brazilian states (São Paulo, Rio de Janeiro, and Minas Gerais) at the municipality level...
December 7, 2016: PLoS Currents
https://www.readbyqxmd.com/read/28102319/temporal-topic-modeling-to-assess-associations-between-news-trends-and-infectious-disease-outbreaks
#5
Saurav Ghosh, Prithwish Chakraborty, Elaine O Nsoesie, Emily Cohn, Sumiko R Mekaru, John S Brownstein, Naren Ramakrishnan
In retrospective assessments, internet news reports have been shown to capture early reports of unknown infectious disease transmission prior to official laboratory confirmation. In general, media interest and reporting peaks and wanes during the course of an outbreak. In this study, we quantify the extent to which media interest during infectious disease outbreaks is indicative of trends of reported incidence. We introduce an approach that uses supervised temporal topic models to transform large corpora of news articles into temporal topic trends...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28044249/evaluation-of-facebook-and-twitter-monitoring-to-detect-safety-signals-for-medical-products-an-analysis-of-recent-fda-safety-alerts
#6
Carrie E Pierce, Khaled Bouri, Carol Pamer, Scott Proestel, Harold W Rodriguez, Hoa Van Le, Clark C Freifeld, John S Brownstein, Mark Walderhaug, I Ralph Edwards, Nabarun Dasgupta
INTRODUCTION: The rapid expansion of the Internet and computing power in recent years has opened up the possibility of using social media for pharmacovigilance. While this general concept has been proposed by many, central questions remain as to whether social media can provide earlier warnings for rare and serious events than traditional signal detection from spontaneous report data. OBJECTIVE: Our objective was to examine whether specific product-adverse event pairs were reported via social media before being reported to the US FDA Adverse Event Reporting System (FAERS)...
April 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28017559/spread-of-yellow-fever-virus-outbreak-in-angola-and-the-democratic-republic-of-the-congo-2015-16-a-modelling-study
#7
Moritz U G Kraemer, Nuno R Faria, Robert C Reiner, Nick Golding, Birgit Nikolay, Stephanie Stasse, Michael A Johansson, Henrik Salje, Ousmane Faye, G R William Wint, Matthias Niedrig, Freya M Shearer, Sarah C Hill, Robin N Thompson, Donal Bisanzio, Nuno Taveira, Heinrich H Nax, Bary S R Pradelski, Elaine O Nsoesie, Nicholas R Murphy, Isaac I Bogoch, Kamran Khan, John S Brownstein, Andrew J Tatem, Tulio de Oliveira, David L Smith, Amadou A Sall, Oliver G Pybus, Simon I Hay, Simon Cauchemez
BACKGROUND: Since late 2015, an epidemic of yellow fever has caused more than 7334 suspected cases in Angola and the Democratic Republic of the Congo, including 393 deaths. We sought to understand the spatial spread of this outbreak to optimise the use of the limited available vaccine stock. METHODS: We jointly analysed datasets describing the epidemic of yellow fever, vector suitability, human demography, and mobility in central Africa to understand and predict the spread of yellow fever virus...
March 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28012555/corrigendum-to-surface-water-areas-significantly-impacted-2014-dengue-outbreaks-in-guangzhou-china-environ-res-150-2016-299-305
#8
Huaiyu Tian, Shanqian Huang, Sen Zhou, Peng Bi, Zhicong Yang, Xiujun Li, Lifan Chen, Bernard Cazelles, Jing Yang, Lei Luo, Qinlong Jing, Wenping Yuan, Yao Pei, Zhe Sun, Tianxiang Yue, Mei-PoK Wan, Qiyong Liu, Ming Wang, Shilu Tong, John S Brownstein, Bing Xu
No abstract text is available yet for this article.
April 2017: Environmental Research
https://www.readbyqxmd.com/read/27817958/media-content-about-vaccines-in-the-united-states-and-canada-2012-2014-an-analysis-using-data-from-the-vaccine-sentimeter
#9
Guido Antonio Powell, Kate Zinszer, Aman Verma, Chi Bahk, Lawrence Madoff, John Brownstein, David Buckeridge
BACKGROUND: A system for monitoring vaccine-related media content was previously developed and studied from an international perspective. This monitoring approach could also have value at a regional level, but it has yet to be evaluated at this scale. We examined regional patterns of vaccine-related media topics and sentiment in the US and Canada. METHODS: We extracted vaccine-relevant US and Canadian online media reports between June 2012 and October 2014 from the Vaccine Sentimeter, a HealthMap-based automated media monitoring system for news aggregators and blogs...
December 7, 2016: Vaccine
https://www.readbyqxmd.com/read/27759033/the-growth-of-the-central-region-by-acquisition-of-counterrotating-gas-in-star-forming-galaxies
#10
Yan-Mei Chen, Yong Shi, Christy A Tremonti, Matt Bershady, Michael Merrifield, Eric Emsellem, Yi-Fei Jin, Song Huang, Hai Fu, David A Wake, Kevin Bundy, David Stark, Lihwai Lin, Maria Argudo-Fernandez, Thaisa Storchi Bergmann, Dmitry Bizyaev, Joel Brownstein, Martin Bureau, John Chisholm, Niv Drory, Qi Guo, Lei Hao, Jian Hu, Cheng Li, Ran Li, Alexandre Roman Lopes, Kai-Ke Pan, Rogemar A Riffel, Daniel Thomas, Lan Wang, Kyle Westfall, Ren-Bin Yan
Galaxies grow through both internal and external processes. In about 10% of nearby red galaxies with little star formation, gas and stars are counter-rotating, demonstrating the importance of external gas acquisition in these galaxies. However, systematic studies of such phenomena in blue, star-forming galaxies are rare, leaving uncertain the role of external gas acquisition in driving evolution of blue galaxies. Here, based on new measurements with integral field spectroscopy of a large representative galaxy sample, we find an appreciable fraction of counter-rotators among blue galaxies (9 out of 489 galaxies)...
October 19, 2016: Nature Communications
https://www.readbyqxmd.com/read/27684332/yellow-fever-vaccination-coverage-heterogeneities-in-luanda-province-angola
#11
Maimuna S Majumder, Colleen M Nguyen, Sumiko R Mekaru, John S Brownstein
No abstract text is available yet for this article.
September 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27665707/evaluating-the-performance-of-infectious-disease-forecasts-a-comparison-of-climate-driven-and-seasonal-dengue-forecasts-for-mexico
#12
Michael A Johansson, Nicholas G Reich, Aditi Hota, John S Brownstein, Mauricio Santillana
Dengue viruses, which infect millions of people per year worldwide, cause large epidemics that strain healthcare systems. Despite diverse efforts to develop forecasting tools including autoregressive time series, climate-driven statistical, and mechanistic biological models, little work has been done to understand the contribution of different components to improved prediction. We developed a framework to assess and compare dengue forecasts produced from different types of models and evaluated the performance of seasonal autoregressive models with and without climate variables for forecasting dengue incidence in Mexico...
September 26, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27649306/global-capacity-for-emerging-infectious-disease-detection-1996-2014
#13
Sheryl A Kluberg, Sumiko R Mekaru, David J McIver, Lawrence C Madoff, Adam W Crawley, Mark S Smolinski, John S Brownstein
The speed with which disease outbreaks are recognized is critical for establishing effective control efforts. We evaluate global improvements in the timeliness of outbreak discovery and communication during 2010-2014 as a follow-up to a 2010 report. For all outbreaks reported by the World Health Organization's Disease Outbreak News, we estimate the number of days from first symptoms until outbreak discovery and until first public communication. We report median discovery and communication delays overall, by region, and by Human Development Index (HDI) quartile...
October 2016: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27618573/reconstruction-of-zika-virus-introduction-in-brazil
#14
Kate Zinszer, Kathryn Morrison, John S Brownstein, Fatima Marinho, Alexandre F Santos, Elaine O Nsoesie
We estimated the speed of Zika virus introduction in Brazil by using confirmed cases at the municipal level. Our models indicate a southward pattern of introduction starting from the northeastern coast and a pattern of movement toward the western border with an average speed of spread of 42 km/day or 15,367 km/year.
January 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27593584/potential-for-zika-virus-introduction-and-transmission-in-resource-limited-countries-in-africa-and-the-asia-pacific-region-a-modelling-study
#15
Isaac I Bogoch, Oliver J Brady, Moritz U G Kraemer, Matthew German, Maria I Creatore, Shannon Brent, Alexander G Watts, Simon I Hay, Manisha A Kulkarni, John S Brownstein, Kamran Khan
BACKGROUND: As the epidemic of Zika virus expands in the Americas, countries across Africa and the Asia-Pacific region are becoming increasingly susceptible to the importation and possible local spread of the virus. To support public health readiness, we aim to identify regions and times where the potential health, economic, and social effects from Zika virus are greatest, focusing on resource-limited countries in Africa and the Asia-Pacific region. METHODS: Our model combined transportation network analysis, ecological modelling of mosquito occurrences, and vector competence for flavivirus transmission, using data from the International Air Transport Association, entomological observations from Zika's primary vector species, and climate conditions using WorldClim...
November 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27457472/environment-wide-association-study-of-blood-pressure-in-the-national-health-and-nutrition-examination-survey-1999-2012
#16
Denise P McGinnis, John S Brownstein, Chirag J Patel
Identifying environmental exposures associated with blood pressure is a priority. Recently, we proposed the environment-wide association study to search for and replicate environmental factors associated with phenotypes. We conducted the environment-wide association study (EWAS) using the National Health and Nutrition Examination Surveys (1999-2012) which evaluated a total of 71,916 participants to prioritize environmental factors associated with systolic and diastolic blood pressure. We searched for factors on participants from survey years 1999-2006 and tentatively replicated findings in participants from years 2007-2012...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27443670/genetic-evidence-for-avian-influenza-h5n1-viral-transmission-along-the-black-sea-mediterranean-flyway
#17
Sen Zhou, Huaiyu Tian, Xiaoxu Wu, Bo Xu, Jing Yang, Karen Kie Yan Chan, Shanqian Huang, Lu Dong, John Brownstein, Bing Xu
The current epidemic of highly pathogenic avian influenza H5N1 virus is considered to pose a significant threat to the health of wild and domestic avian species, and even to human beings. The Black Sea-Mediterranean Flyway is one of the most important epidemic areas of H5N1. However, the epidemic along this flyway has not been fully explored. To better understand the role of hosts in the spread and evolution of H5N1 virus along the flyway, a phylogeographic study was conducted using haemagglutinin (HA) gene sequences obtained during 2005-2013...
September 2016: Journal of General Virology
https://www.readbyqxmd.com/read/27415615/disease-surveillance-on-complex-social-networks
#18
Jose L Herrera, Ravi Srinivasan, John S Brownstein, Alison P Galvani, Lauren Ancel Meyers
As infectious disease surveillance systems expand to include digital, crowd-sourced, and social network data, public health agencies are gaining unprecedented access to high-resolution data and have an opportunity to selectively monitor informative individuals. Contact networks, which are the webs of interaction through which diseases spread, determine whether and when individuals become infected, and thus who might serve as early and accurate surveillance sensors. Here, we evaluate three strategies for selecting sensors-sampling the most connected, random, and friends of random individuals-in three complex social networks-a simple scale-free network, an empirical Venezuelan college student network, and an empirical Montreal wireless hotspot usage network...
July 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27357212/analysis-of-primary-visual-cortex-in-dementia-with-lewy-bodies-indicates-gabaergic-involvement-associated-with-recurrent-complex-visual-hallucinations
#19
Ahmad A Khundakar, Peter S Hanson, Daniel Erskine, Nichola Z Lax, Joseph Roscamp, Evangelia Karyka, Eliona Tsefou, Preeti Singh, Simon J Cockell, Andrew Gribben, Lynne Ramsay, Peter G Blain, Urs P Mosimann, Deborah J Lett, Matthias Elstner, Douglass M Turnbull, Charles C Xiang, Michael J Brownstein, John T O'Brien, John-Paul Taylor, Johannes Attems, Alan J Thomas, Ian G McKeith, Christopher M Morris
Dementia with Lewy bodies (DLB) patients frequently experience well formed recurrent complex visual hallucinations (RCVH). This is associated with reduced blood flow or hypometabolism on imaging of the primary visual cortex. To understand these associations in DLB we used pathological and biochemical analysis of the primary visual cortex to identify changes that could underpin RCVH. Alpha-synuclein or neurofibrillary tangle pathology in primary visual cortex was essentially absent. Neurone density or volume within the primary visual cortex in DLB was also unchanged using unbiased stereology...
June 30, 2016: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/27336234/surface-water-areas-significantly-impacted-2014-dengue-outbreaks-in-guangzhou-china
#20
Huaiyu Tian, Shanqian Huang, Sen Zhou, Peng Bi, Zhicong Yang, Xiujun Li, Lifan Chen, Bernard Cazelles, Jing Yang, Lei Luo, Qinlong Jing, Wenping Yuan, Yao Pei, Zhe Sun, Tianxiang Yue, Mei-Po Kwan, Qiyong Liu, Ming Wang, Shilu Tong, John S Brownstein, Bing Xu
Dengue transmission in urban areas is strongly influenced by a range of biological and environmental factors, yet the key drivers still need further exploration. To better understand mechanisms of environment-mosquito-urban dengue transmission, we propose an empirical model parameterized and cross-validated from a unique dataset including viral gene sequences, vector dynamics and human dengue cases in Guangzhou, China, together with a 36-year urban environmental change maps investigated by spatiotemporal satellite image fusion...
October 2016: Environmental Research
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