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Elena Pérez-Arellano, María Isabel Rodriguez-Garcia, Ana Belen Galera Rodenas, Emilio de la Morena-Madrigal
INTRODUCTION: The eradication of Helicobacter pylori infection represents a clinical challenge. OBJECTIVE: To evaluate the efficacy and safety of quadruple therapy with esomeprazole plus a 3-in-1 capsule containing bismuth subcitrate, metronidazole and tetracycline, plus probiotics in patients diagnosed with H. pylori infection in routine clinical practice. METHODS: A prospective, interventional, single-centre and open-label study in consecutive patients with a confirmed indication for eradication of H...
October 17, 2017: Gastroenterología y Hepatología
Irene Fernanández-Ruiz
No abstract text is available yet for this article.
October 20, 2017: Nature Reviews. Cardiology
Saeed Ghobadi, Shiva Faghih
AIM: We aimed to investigate the association of eating meals while television viewing (TVV) and screen-based behaviors with cardio metabolic risk factors (CRFs) among school-aged children in Shiraz. MATERIALS AND METHODS: This cross-sectional study was done on 409 primary school children (217 boys), aged 6-9 years. Physical activity, time spent on screen-based behaviors and frequency of eating meals while TVV were measured using a questionnaire. Anthropometric indices, fasting blood sugar (FBS), blood lipids, blood pressure (BP), dietary intakes and physical activity were assessed...
September 22, 2017: Diabetes & Metabolic Syndrome
Nadiyah Abdullah Al-Mountashiri, Amal Mohammad Al-Zhrani, Shereen Fawzy Hafez Ibrahim, Hyder Othman Mirghani
BACKGROUND: Medical nutritional therapy is an important aspect of diabetes care, there is an increasing awareness of breakfast skipping, late dinner and meal contents on diabetes control. AIM: To assess dietary habits, physical activity and diabetes perception among patients with type 2 diabetes. METHODS: This case-control study was conducted among patients with diabetes mellitus at the diabetes center in Tabuk City, Saudi Arabia during the period from March through June 2017...
September 2017: Electronic Physician
Andrea Helo, Sandrien van Ommen, Sebastian Pannasch, Lucile Danteny-Dordoigne, Pia Rämä
Conceptual representations of everyday scenes are built in interaction with visual environment and these representations guide our visual attention. Perceptual features and object-scene semantic consistency have been found to attract our attention during scene exploration. The present study examined how visual attention in 24-month-old toddlers is attracted by semantic violations and how perceptual features (i. e. saliency, centre distance, clutter and object size) and linguistic properties (i. e. object label frequency and label length) affect gaze distribution...
October 10, 2017: Infant Behavior & Development
Maulik R Patel, Kevinkumar A Kansagra, Devang P Parikh, Deven V Parmar, Hardik B Patel, Mayur M Soni, Uday S Patil, Harilal V Patel, Jaimik A Patel, Swagat S Gujarathi, Krupi V Parmar, Nuggehally R Srinivas
BACKGROUND AND OBJECTIVE: Peroxisome proliferator-activated receptors (PPARs) have recently become a focus of interest for their important roles in glucose and lipid metabolism. In humans, PPARα activation causes a decrease in plasma triglyceride (TG) levels, enhancement of high-density lipoprotein cholesterol (HDL-C) and simultaneous enhancement of very-low-density lipoprotein (VLDL) lipolysis, whereas PPARγ agonists act as insulin sensitizers and improve insulin resistance, which is very useful in patients with type 2 diabetes mellitus (T2DM)...
October 11, 2017: Clinical Drug Investigation
Prakash Deedwania, Tushar Acharya
No abstract text is available yet for this article.
October 10, 2017: Journal of the American College of Cardiology
Irina Uzhova, Valentín Fuster, Antonio Fernández-Ortiz, José M Ordovás, Javier Sanz, Leticia Fernández-Friera, Beatriz López-Melgar, José M Mendiguren, Borja Ibáñez, Héctor Bueno, José L Peñalvo
BACKGROUND: Daily habits, including the number and quality of eating occasions, are potential targets for primary prevention strategies with large health impacts. Skipping breakfast is considered a frequent and unhealthy habit associated with an increased cardiovascular (CV) risk. OBJECTIVES: The study sought to explore the association between different breakfast patterns and CV risk factors and the presence, distribution, and extension of subclinical atherosclerosis...
October 10, 2017: Journal of the American College of Cardiology
Akram Mehrabbeik, Seyed Saeed Mazloomy Mahmoodabad, Hassan Mozaffari Khosravi, Hossein Fallahzadeh
BACKGROUND AND AIM: Despite the importance of breakfast, especially for students, unfortunately, this meal is usually ignored in daily routine. The aim of this study was to identify determinants among female high school students of Yazd province based on the Pender Health Promotion Model. METHODS: This was a cross-sectional study conducted to examine 200 female high school students of Yazd, selected by cluster sampling method in 2016. A researcher-made questionnaire, based on Pender's Health Promotion Model, was used as a data collection tool...
August 2017: Electronic Physician
Mariangela da Silva Alves Batista, Lenise Mondini, Patrícia Constante Jaime
OBJECTIVE: to describe the experience in the municipality of Itapevi-SP, Brazil, within the framework of School Health Program and school meals related to overweight prevention. METHODS: this cross-sectional study comprised 21 public schools of the first cycle of Primary School who adhered to the School Health Program; the diagnoses, based on 2014 data, included the students' nutritional status, qualitative analysis of school meals, and inclusion of themes related to nutrition and physical activities in curricular and extracurricular activities...
July 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
Hazel Hunt, Kirsteen Donaldson, Mark Strem, Vanessa Zann, Pui Leung, Suzanne Sweet, Alyson Connor, Dan Combs, Joseph Belanoff
CORT125134 is an orally active, high-affinity, selective antagonist of the glucocorticoid receptor that is being developed for indications that may benefit from the modulation of cortisol activity. This first-in-human study was conducted to evaluate the dose-related safety, tolerability, pharmacokinetics and pharmacological effects of CORT125134 and its active metabolite CORT125201. Eighty-one healthy male or female subjects received a single dose of 5 to 500 mg CORT125134 or matching placebo across 9 cohorts; 1 cohort received 150 mg CORT125134 after a high-fat breakfast; and 46 subjects received 50 to 500 mg CORT125134 or matching placebo once daily for up to 14 days across 4 cohorts...
October 2, 2017: Clinical Pharmacology in Drug Development
Cathy K Gelotte, Brenda A Zimmerman, Gary A Thompson
Diphenhydramine pharmacokinetics were characterized following a single oral dose in children aged 2 to 17 years using a weight- and age-based dosing schedule with more tiers than the current age-based dosing schedule recommended by the nonprescription drug monograph. This study was conducted in 42 subjects, aged 2 to 17 years. Doses were based on a weight-age dosing schedule, ranging from 6.25 to 50 mg. An oral dose was administered with water about 2 hours after a light breakfast. Plasma samples were obtained up to 48 hours after dosing and analyzed for diphenhydramine...
October 2, 2017: Clinical Pharmacology in Drug Development
Andrea Poscia, Adele Anna Teleman, Elena Azzolini, Chiara de Waure, Davide Maged, Andrea Virdis, Walter Ricciardi, Maria Luisa Di Pietro
OBJECTIVE: To analyze breakfast consumption, regularity of meals, fruit and vegetable consumption in the Italian university student population on a national level. DESIGN: Descriptive analysis evaluating data taken from the Sportello Salute Giovani (SSG) questionnaire. PARTICIPANTS: 12 000 university students who self-administered a confidential survey. 8292 questionnaires were analyzed. VARIABLES MEASURED: Age; sex; self-reported economic status; BMI; number of breakfast and portions of vegetables and portions of fruit usually consumed per week; number of eating episodes per day; intended weight loss...
July 2017: Annali Dell'Istituto Superiore di Sanità
Mahdieh Kamalpour, Hamid Ghalandari, Javad Nasrollahzadeh
The purpose of this study was to compare effects of a moderate carbohydrate diet supplemented with psyllium with those of a lower carbohydrate diet supplemented with placebo powder on glycemic control in patients with type 2 diabetes (T2D). In an open randomized controlled trial, 37 patients with T2D with body mass index (BMI) 25-35 kg/m2 received either a low-energy, moderate carbohydrate diet plus 7 grams of psyllium powder (MoCyllium group) or a low-energy, lower carbohydrate diet plus placebo powder (LoCarb group) for 2 weeks...
September 28, 2017: Journal of Dietary Supplements
Elangbam Lamalakshmi Devi, Firoz Hossain, Vignesh Muthusamy, Rashmi Chhabra, Rajkumar Uttamrao Zunjare, Aanchal Baveja, Sunil Kumar Jaiswal, Rajat Goswami, Sweta Dosad
Waxy corn possesses 95-100% amylopectin, compared to 70-75% in normal maize, owing to mutation in Wx gene encoding a granule-bound starch synthase I. Amylopectin is used as an ingredient in textile, adhesive and paper industries. Further, waxy green cob is popular as breakfast item in South Asia and an important constituent of diet in north-eastern states of India as well. We developed a series of waxy inbreds from diverse exotic sources and through introgression breeding. To characterize and unravel the genetic relationships, 24 diverse waxy inbreds were analysed using 77 SSRs distributed throughout the genome...
October 2017: 3 Biotech
Marinos Fysekidis, Emmanuel Cosson, Karim Takbou, Angela Sutton, Nathalie Charnaux, Isabella Banu, Eric Vicaut, Paul Valensi
BACKGROUND: A single insulin injection was shown to improve microcirculatory blood flow. Our aim was to examine the effects of 4weeks of insulin therapy by three randomly assigned insulin analog regimens (Detemir, Aspart, and their combination) on cutaneous blood flow (CBF) and microcirculatory endothelial function as an add-on to metformin in type 2 diabetic patients poorly controlled on oral antidiabetic treatment. METHODS: Fourty-two type 2 diabetic patients with no history of cardiovascular disease in secondary failure to oral antidiabetic agents had CBF measurements before and after acetylcholine (Ach) iontophoretic administration...
September 24, 2017: Microvascular Research
Stephen A Mears, Kathryn Dickinson, Kurt Bergin-Taylor, Reagan Dee, Jack Kay, Lewis J James
PURPOSE: To examine the effect on short duration, high intensity cycling time trial performance when a semi-solid breakfast containing carbohydrate or a taste and texture matched placebo is ingested 90 minutes pre-exercise compared to a water control. METHODS: Thirteen well trained cyclists (25 ± 8 years, 71.1 ± 5.9 kg, 1.76 ± 0.04 m, 383 ± 46 Wmax, VO2peak 4.42 ± 0.53 L·min(-1)) performed three experimental trials examining breakfast ingestion 90 minutes before a 10 minute steady state cycle (60% Wmax) and a ~20 minute time trial (to complete a workload target of 376 ± 36 kJ)...
September 27, 2017: International Journal of Sports Physiology and Performance
Sajani Raman, Sara Guerrero-Duby, Jennifer L McCullough, Miraides Brown, Sarah Ostrowski-Delahanty, Diane Langkamp, John C Duby
This cross-sectional study assessed associations between social-emotional development in young children and their number of daily routines involving an electronic screen. We hypothesized children with poor social-emotional development have a significant portion of daily routines occurring with a screen. Two hundred and ten female caregivers of typically developing children 12 to 36 months old completed the Ages and Stages Questionnaire: Social-Emotional (ASQ: SE) and a media diary. Caregivers completed the diary for 1 day around 10 daily routines (Waking Up, Diapering/Toileting, Dressing, Breakfast, Lunch, Naptime, Playtime, Dinner, Bath, and Bedtime)...
November 2017: Clinical Pediatrics
Magdalena Zalewska, Elżbieta Maciorkowska
INTRODUCTION: A balanced diet is at the heart of healthy growth and development of children and youth, whereas inappropriate eating habits considerably influence the incidence of disorders connected with nutrition, including overweight and obesity. This paper aims at studying nutritional factors of 18-year-old secondary school youth in the urban environment and their effect on the incidence of overweight and obesity. MATERIALS AND METHODS: The survey was conducted among 1,999 secondary school students chosen at random...
2017: PeerJ
Nicole Larson, Qi Wang, Katherine Grannon, Susan Wei, Marilyn S Nanney, Caitlin Caspi
OBJECTIVE: Evaluate the impact of a grab-and-go component embedded within a larger intervention designed to promote School Breakfast Program (SBP) participation. DESIGN: Secondary data analysis. SETTING: Rural Minnesota high schools. PARTICIPANTS: Eight schools were enrolled in the grab-and-go only intervention component. An at-risk sample of students (n = 364) who reported eating breakfast ≤3 d/wk at baseline was enrolled at these schools...
September 23, 2017: Journal of Nutrition Education and Behavior
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