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Sarah Schatschneider, Salah Abdelrazig, Laudina Safo, Anne Meint Henstra, Thomas Millat, Dong-Hyun Kim, Klaus Winzer, Nigel Peter Minton, David A Barrett
We have investigated the applicability of commercially available lyophilised Spirulina ( Arthrospira platensis), a microorganism uniformly labelled with13 C, as a readily accessible source of multiple13 C-labelled metabolites suitable as internal standards for quantitative determination of intracellular bacterial metabolites. Metabolites of interest were analysed by hydrophilic interaction liquid chromatography coupled with high resolution mass spectrometry. Multiple internal standards obtained from uniformly (U)-13 C-labelled extract from Spirulina were used to enable isotope dilution mass spectrometry (IDMS) for the identification and quantification of the intracellular metabolites...
March 13, 2018: Analytical Chemistry
Brianne A Altmann, Carmen Neumann, Susanne Velten, Frank Liebert, Daniel Mörlein
The effects on meat quality resulting from alternative dietary protein sources (Spirulina and Hermetia meal) in poultry diets are studied to determine the overall suitability of these ingredients considering state-of-the-art packaging practices-highly oxygenated modified atmosphere packaging (HiOx MAP). We monitored standard slaughterhouse parameters, such as live weight, carcass weight, dressed yield, and pH at 20 min and 24 h post mortem. In addition, we studied the effects that 3 and 7-day storage in HiOx MAP has on the overall product physico-chemical and sensory properties...
March 8, 2018: Foods (Basel, Switzerland)
Suelen Goettems Kuntzler, Ana Claudia Araujo de Almeida, Jorge Alberto Vieira Costa, Michele Greque de Morais
Polymer nanofibers produced by electrospinning are promising for use in food packaging because of their nanometric diameter, which provides a barrier to external conditions above the possible incorporation of the active compounds. The microalga Spirulina sp. LEB 18 synthesizes bioproducts, such as polyhydroxybutyrate (PHB), which is biodegradable and has similar mechanical and thermal properties to polymers of petrochemical origin. Moreover, phenolic compounds of microalgae have antibacterial, antifungal, and antioxidant activities, which is a differential for the development of packaging...
March 2, 2018: International Journal of Biological Macromolecules
Eun-Jeong Koh, Kui-Jin Kim, Jia Choi, Do-Hyung Kang, Boo-Yong Lee
Spirulina maxima is a blue-green micro alga that contains abundant amounts of proteins (60-70%), vitamins, chlorophyll a, and C-phycocyanin (C-PC). It has been shown to reduce oxidative stress, and prevent diabetes and non-alcoholic fatty liver disease. However, it is unclear whether Spirulina maxima 70% ethanol extract (SM70EE), chlorophyll a, and C-PC prevent Aβ1-42 -induced neurotoxicity in PC12 cells. The aim of this study was to investigate whether SM70EE, chlorophyll a, and C-PC prevent Aβ1-42 -induced cell death...
February 27, 2018: Neuroscience Letters
Kurt Appel, Eduardo Munoz, Carmen Navarrete, Cristina Cruz-Teno, Andreas Biller, Eva Thiemann
Immulina® , a high-molecular-weight polysaccharide extract from the cyanobacterium Arthrospira platensis ( Spirulina ) is a potent activator of innate immune cells. On the other hand, it is well documented that Spirulina exerts anti-inflammatory effects and showed promising effects with respect to the relief of allergic rhinitis symptoms. Taking into account these findings, we decided to elucidate whether Immulina® , and immunLoges® (a commercial available multicomponent nutraceutical with Immulina® as a main ingredient) beyond immune-enhancing effects, might also exert inhibitory effects in the induced allergic inflammatory response and on histamine release from RBL-2H3 mast cells...
February 26, 2018: Plants (Basel, Switzerland)
Lydia Ould Amara-Leffad, Houria Ramdane, Khaoula Nekhoul, Amira Ouznadji, Elhadj Ahmed Koceir
Spirulina platensis, is an alga rich in phycocyanin (potent antioxidant), is effective in regulating the balance of oxidative stress. The objective of this study is to observe the impact of ingestion of a highly oxidised vegetable oil, by rats of Wistar strain. Finally, we observe the effect of Spirulina used as an antioxidant treatment, on rats having ingested a diet rich in highly oxidised oil. Physiological, biochemical and histological studies have been carried out; the oxidative stress parameters evaluated and a dosing of Cytochrome P450 2E1 was finally carried out...
February 27, 2018: Archives of Physiology and Biochemistry
C Tuck, E Ly, A Bogatyrev, I Costetsou, P Gibson, J Barrett, J Muir
BACKGROUND: The low FODMAP (fermentable, oligo-, di-, mono-saccharides and polyols) diet is an effective strategy to improve symptoms of irritable bowel syndrome. However, combining the low FODMAP diet with another dietary restriction such as vegetarianism/veganism is challenging. Greater knowledge about the FODMAP composition of plant-based foods and food processing practices common to vegetarian/vegan eating patterns would assist in the implementation of the diet in this patient population...
February 23, 2018: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
Ekaterina Yu Afonina, Natalya A Tashlykova
The plankton community of sixteen saline lakes located on Onon-Torey plain (Northeastern Mongolia) during the filling phase and the raising of the water level was investigated in July 2011. Thirty-five taxa of phytoplankton and thirty-one species of zooplankton were found. For phytoplankton, blue-green algae ( Merismopedia elegans , Anabaenopsis elenkinii , Arthrospora fusiformis , Spirulina major , Lyngbya sp., Oscillatoria sp.) and green algae ( Monoraphidium minutum , Tetrastrum komarekii , Ankyra ocellata , Oocystis sp...
February 2018: Saudi Journal of Biological Sciences
Ki Mo Kim, Joo Young Lee, A-Rang Im, Sungwook Chae
Phycocyanin (Pc) is one of the active pigment constituents of Spirulina microalgae. It has been used for its potent antioxidant and anti-inflammatory properties. However, the protective effects of Pc against ultraviolet-B (UVB)-induced primary skin cells damage are still undefined. In the present study, we investigated whether Pc prevented UVB-induced apoptotic cell death in human dermal fibroblasts (HDF) and human epidermal keratinocytes (HEK). Pc induced the transcription of heme oxygenase-1 (HO-1). Furthermore, Pc treatments resulted in a marked increase in nuclear factor erythroid-derived 2 (NF-E2)-like 2 (Nrf-2) nuclear translocation...
February 22, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Artur Juszkiewicz, Piotr Basta, Elżbieta Petriczko, Bogusław Machaliński, Jerzy Trzeciak, Karolina Łuczkowska, Anna Skarpańska-Stejnborn
Background: The aim of this study was to analyze the response of selected components of the immune system in rowers to maximal physical exercise, and to verify if this response can be modulated by supplementation with spirulina (cyanobacterium Spirulina platensis ) . Method: The double-blind study included 19 members of the Polish Rowing Team. The subjects were randomly assigned to the supplemented group ( n  = 10), receiving 1500 mg of spirulina extract for 6 weeks, or to the placebo group ( n  = 9)...
2018: Journal of the International Society of Sports Nutrition
María José Fabra, Marta Martínez-Sanz, L G Gómez-Mascaraque, Rafael Gavara, Amparo López-Rubio
This work provides an in-depth analysis on how the addition of different microalgae species (Nannochloropsis, Spirulina and Scenedesmus) affected the structural and physicochemical properties of thermoplastic corn starch biocomposites. Structural characterization was conducted by combined SAXS/WAXS experiments and it was correlated with mechanical and barrier properties of the biocomposites. A water vapour permeability drop of ca. 54% was observed upon addition of the different microalgae species. The oxygen permeability and the mechanical properties of biocomposites containing Spirulina or Scenedesmus were not improved since the presence of microalgae hindered the re-arrangement and packing of the lamellar structure of starch polymeric chains, according to the SAXS results...
April 15, 2018: Carbohydrate Polymers
Jerine Peter Simon, Udhaya Lavinya Baskaran, Kadar Basha Shallauddin, Giridharan Ramalingam, Sabina Evan Prince
The aim of our study is to investigate the protective effect of Spirulina fusiformis against streptozotocin-induced diabetes in Wistar albino rats. Rats were divided into five groups: group I was normal control, group II was diabetic control (50 mg/kg b.w. of streptozotocin, i.p.), group III was Spirulina fusiformis (400 mg/kg b.w., p.o.) treated diabetic rats; group IV was Glibenclamide (0. 6 mg/kg b.w., p.o.) treated diabetic rats and group V was treated with Spirulina fusiformis (400 mg/kg b.w., p.o.) alone...
February 2018: 3 Biotech
H Furbeyre, J van Milgen, T Mener, M Gloaguen, E Labussière
Weaning of piglets is associated with important changes in gut structure and function resulting from stressful events such as separation from the sow, moving to a new facility and dietary transition from a liquid to a solid feed. This may result in post-weaning diarrhoea and a decrease in feed intake and growth. In humans, the cyanobacterium Spirulina platensis (SP) and the freshwater microalga Chlorella vulgaris (CV) are known for their beneficial health effects. This study aimed to determine the effects of early oral administration of Spirulina and Chlorella in piglets on mucosal architecture and cytokine expression in the intestine around weaning, and consequences on growth performance and diarrhoea incidence...
February 15, 2018: Animal: An International Journal of Animal Bioscience
Cristiane Santos de Jesus, Lívia da Silva Uebel, Samantha Serra Costa, Andréa Lobo Miranda, Etiele Greque de Morais, Michele Greque de Morais, Jorge Alberto Vieira Costa, Itaciara Larroza Nunes, Ederlan de Souza Ferreira, Janice Izabel Druzian
This study evaluated whether outdoor cultivation of Spirulina sp. in different geographical locations affected its growth and biomass quality, with respect to the chemical composition, volatile compound and heavy metal content, and thermal stability. The positive effect of solar radiation and temperature on biomass productivity in Spirulina sp. cultivated in the northeast was directly related to its improved nutritional characteristics, which occurred with an increase in protein, phycocyanin, and polyunsaturated fatty acid (mainly γ-linolenic) content...
February 9, 2018: Bioresource Technology
Denise da Fontoura Prates, Elisângela Martha Radmann, Jessica Hartwig Duarte, Michele Greque de Morais, Jorge Alberto Vieira Costa
This study evaluated light emitting diodes (LEDs) as a light source in Spirulina sp. LEB 18 cultures in terms of growth parameters and biomass composition. Different photoperiods (partial and integral) and colors (blue, green, red and white) were assessed. Blue, green, red and white LEDs increased biomass productivity and maximum specific growth rate of such cultivations. The maximum biomass concentration (1.77 ± 0.02 g L -1 ) was obtained when red LEDs in integral light photoperiod were applied to cultivations...
January 31, 2018: Bioresource Technology
Emmanuel Manirafasha, Theophile Murwanashyaka, Theoneste Ndikubwimana, Nur Rashid Ahmed, Jingyi Liu, Yinghua Lu, Xianhai Zeng, Xueping Ling, Keju Jing
Arthrospira (Spirulina) platensis is known to have high-quality proteins content and phycocyanin as one of the major pigment constituents of the cells, and the most challenging problem associated with phycocyanin production in Arthrospira is to optimize its intracellular accumulation. The present study evaluated the metabolic stress conditions (by nutrient enrichment) of Arthrospira platensis FACHB-314 for boosting biomass growth and high content phycocyanin accumulation. Experimental results showed that 5 mM sodium glutamate and 7...
December 23, 2017: Bioresource Technology
Liangqian Jiang, Yujuan Wang, Guoxiang Liu, Huihui Liu, Feng Zhu, Huanhuan Ji, Bing Li
Background: Triple-negative breast cancer is a biological subtype of breast cancer, which is unresponsive to conventional chemotherapies and has a poor prognosis. C-Phycocyanin (C-PC), a marine natural purified from Spirulina platensis, has been investigated that has anti-cancer function. The mitogen activated protein kinase (MAPK) pathway plays a crucial role in the development and progression of cancer. Therefore, we would like to study the anti-cancer effects of C-phycocyanin in the treatment of triple-negative breast cancer, and explore the role of MAPK pathway in the anti-tumor effects of C-phycocyanin...
2018: Cancer Cell International
Zijian Liu, Xiang Fu, Wei Huang, Chunxia Li, Xinyan Wang, Bei Huang
Selenium-containing phycocyanin (Se-PC) has been proved to have many biological effects, including anti-inflammatory and antioxidant. In this study, we investigated the photodynamic therapy (PDT) effects of Se-PC against liver tumour in vitro and in vivo experiment. Our results demonstrated that the half lethal dose of Se-PC PDT on HepG2 cells was 100μg/ml PC containing 20% selenium. Se-PC location migration from lysosomes to mitochondria was time dependent. In in vivo experiments, the tumour inhibition rate was 75...
December 20, 2017: Journal of Photochemistry and Photobiology. B, Biology
Felix LewisOscar, Chari Nithya, Sulaiman Ali Alharbi, Naiyf S Alharbi, Nooruddin Thajuddin
Biofilm forming pathogenic bacteria showing resistance towards antimicrobial agents has increased the urge to find an alternative treatment strategy. Among the biofilm forming pathogenic bacteria, Pseudomonas aeruginosa is a well-recognised Gram negative biofilm former causing nosocomial infection and other disease among immunocompromised patients. The aim of the current study is to evaluate the antipathogenic potentials of S. platensis against P. aeruginosa. S. platensis methanolic extract (SME) inhibited the biofilm (89%), extracellular polymeric substances (EPS), cell surface hydrophobicity (CSH) (44%), pyocyanin, pyoveridin and swarming motility of P...
January 31, 2018: Microbial Pathogenesis
Fayza M Aly, Ahmed M Kotb, Seddik Hammad
Todays, bioactive compounds extracted from Spirulina platensis have been intensively studied for their therapeutical values. Therefore, in the present study, we aimed to evaluate the effects of S. platensis extract on DNA damage and chromosomal aberrations induced by cadmium in rats. Four groups of male albino rats (n = 7 rats) were used. The first group served as a control group and received distilled water. The second group was exposed intraperitoneally to cadmium chloride (CdCl2) (3.5 mg/kg body weight dissolved in 2 ml distilled water)...
February 3, 2018: Environmental Science and Pollution Research International
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