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https://www.readbyqxmd.com/read/28636628/effects-of-spirulina-on-the-functions-and-redox-status-of-auditory-system-in-senescence-accelerated-prone-8-mice
#1
Yin-Ching Chan, Juen-Haur Hwang
To our knowledge, the effects of Spirulina platensis water extract (SP) on hearing function have not yet been reported. This study investigated the effects of SP on the function and redox status of the auditory system. Auditory brainstem responses and redox status were compared between two groups of 3-month-old senescence-accelerated prone-8 (SAMP8) mice: the control group was fed a normal diet, and the experimental group was fed a normal diet with oral supplementation of SP for 6 weeks. Compared with the control group, the experimental group had significantly lower hearing thresholds according to auditory brainstem responses measured using click sounds and 8-kHz tone burst sound stimulation at the end of this study...
2017: PloS One
https://www.readbyqxmd.com/read/28632181/spirulina-protects-against-hepatic-inflammation-in-aging-an-effect-related-to-the-modulation-of-the-gut-microbiota
#2
Audrey M Neyrinck, Bernard Taminiau, Hannah Walgrave, Georges Daube, Patrice D Cani, Laure B Bindels, Nathalie M Delzenne
Aging predisposes to hepatic dysfunction and inflammation that can contribute to the development of non-alcoholic fatty liver disease. Spirulina, a cyanobacterium used as a food additive or food supplement, has been shown to impact immune function. We have tested the potential hepatoprotective effect of a Spirulina in aged mice and to determine whether these effects can be related to a modulation of the gut microbiota. Old mice have been fed a standard diet supplemented with or without 5% Spirulina for six weeks...
June 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28629290/functional-foods-how-functional-are-they-a-case-report-of-supplement-induced-psychosis
#3
Priyanka Yadav, Kyle Stigall, Hannah E Johnson, Abner O Rayapati, Nitin Chopra
There is rising evidence of patients' use of alternative and complementary medicine. The percentage of the U.S. population who used at least one dietary supplement increased from 42% in 1988-1994 to 53% in 2003-2006. We present a case of an Asian female in her 40s, with no previous psychiatric illness, who presented to the emergency room following a brief psychotic episode, during which she self-amputated the tips of her fingers, after using multivitamins and herbal supplements including ginseng, gui yuan rou (Chinese herb), astaxanthin, goji (Chinese fruit), selenium, saw palmetto, grape seed extract, citrus bioflavanoid, lutein (zeaxantin), resvexatrol, sun chlorella, spirulina powder, phytoceramides, phytoestrogen, glucosatrin, bromelain plus, and American bee pollen...
August 2016: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28624469/effects-of-protein-sources-on-growth-immunity-and-antioxidant-capacity-of-juvenile-pearl-oyster-pinctada-fucata-martensii
#4
Chuangye Yang, Ruijuan Hao, Yuewen Deng, Yongshan Liao, Qingheng Wang, Ruijiao Sun, Yu Jiao, Xiaodong Du
In this study, we formulated five diets, namely, P1, P2, P3, P4 and P5, with Chlorella sp. powder, Spirulina platensis powder, yeast powder, soybean meal and corn gluten, respectively, as major protein sources. A feeding experiment was designed to evaluate the effects of formulated diets on the growth performance, immunity and antioxidant and biomineralization capacity of juvenile pearl oyster (Pinctada fucata martensii). In the experiments, the five groups were separately fed with P1, P2, P3, P4 and P5 diets...
June 15, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28622709/spirulina-platensis-prevents-hyperglycemia-in-rats-by-modulating-gluconeogenesis-and-apoptosis-via-modification-of-oxidative-stress-and-mapk-pathways
#5
Kadry M Sadek, Mohamed A Lebda, Sherif M Nasr, Moustafa Shoukry
Spirulina platensis (SP) is a microalga with antioxidant, antidiabetic and anti-inflammatory properties. The present study explored the ability and potential mechanism(s) by which SP induced glucose lowering impact in diabetic rat model. Forty rats were allocated into four groups: control; streptozotocin (STZ)-induced diabetes (STZ, 45mg/kg b.w., intraperitoneally); SP (500mg/kg b.w., orally twice weekly for 2 months) and STZ-induced diabetes+SP group. In the STZ-induced diabetic rats, SP significantly decreased (P>0...
June 12, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28617537/spirulina-maxima-improves-insulin-sensitivity-lipid-profile-and-total-antioxidant-status-in-obese-patients-with-well-treated-hypertension-a-randomized-double-blind-placebo-controlled-study
#6
M Szulinska, M Gibas-Dorna, E Miller-Kasprzak, J Suliburska, A Miczke, M Walczak-Gałezewska, M Stelmach-Mardas, J Walkowiak, P Bogdanski
OBJECTIVE: Spirulina maxima consumption is known to be associated with enhanced cardiovascular and metabolic health. Human studies on this topic have recently been described in a few papers; however, potential protective cardiovascular properties of Spirulina in obese patients receiving standard pharmacological antihypertensive treatment remain to be elucidated. Putative beneficial cardiovascular effects of Spirulina supplementation in well treated, obesity-related hypertension were studied in a double-blind placebo-controlled trial...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28593820/spirulina-platensis-biomass-composition-is-influenced-by-the-light-availability-and-harvest-phase-in-raceway-ponds
#7
Francisco Gerhardt Magro, Ana Cláudia Margarites, Christian Oliveira Reinehr, Gabriel Crivellaro Gonçalves, Grazieli Rodigheri, Jorge Alberto Vieira Costa, Luciane Maria Colla
The behavior of cyanobacteria and its potential use for biofuel production in scale-up conditions is a topic of growing importance. The aim of our work is to study the effects of illumination, stirring, and different growth phases on the cultivation of the cyanobacteria Spirulina platensis in 10 L raceways. The cultivations were carried out in a greenhouse under measured, but not controlled, illumination and in agitated raceways with stirring speeds varying from 0.1 to 0.4 m s(-1), using culture media with nutrient depletion...
June 8, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28579523/efficacy-of-spirulina-platensis-diet-supplements-on-disease-resistance-and-immune-related-gene-expression-in-cyprinus-carpio-l-exposed-to-herbicide-atrazine
#8
Samah R Khalil, Rasha M Reda, Ashraf Awad
The present study evaluated the immunotoxicological effects of the herbicide atrazine (ATZ) at sub-lethal concentrations and the potential ameliorative influence of Spirulina platensis (SP) over a sub-chronic exposure period on Cyprinus carpio L., also known as common carp. Common carp was sampled after a 40-days exposure to ATZ (428 μg/L) and SP (1%), individually or in combination to assess the non-specific immune response, changes in mRNA expression of immune-related genes [lysozyme (LYZ), immunoglobulin M (IgM), and complement component 3 (C3)] in the spleen, and inflammatory cytokines (interleukins IL-1ß and IL-10) in the head kidney using real-time PCR...
June 1, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28554489/hepatoprotective-efficacy-of-spirulina-platensis-against-lead-induced-oxidative-stress-and-genotoxicity-in-catfish-clarias-gariepinus
#9
Alaa El-Din H Sayed, Yasser S El-Sayed, Ali H El-Far
Lead (Pb) is a toxic environmental pollutant that induces a broad range of biochemical and physiological hazards in living organisms. We investigated the possible hepatoprotective effects of Spirulina platensis (SP) in counteracting the Pb-induced oxidative damage. Ninety-six adult African catfish were allocated into four equal groups. The 1st group (control) fed basal diet while the 2nd group (Pb-treated) fed on basal diet and exposed to 1mg Pb(NO3)2/L. The 3rd and 4th groups fed SP-supplemented basal diets at levels of 0...
May 27, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28552036/in-vitro-evaluation-of-spirulina-platensis-extract-incorporated-skin-cream-with-its-wound-healing-and-antioxidant-activities
#10
Seda Gunes, Sedef Tamburaci, Meltem Conk Dalay, Ismet Deliloglu Gurhan
CONTEXT: Algae have gained importance in cosmeceutical product development due to their beneficial effects on skin health and therapeutical value with bioactive compounds. Spirulina platensis Parachas (Phormidiaceae) is renowned as a potential source of high-value chemicals and recently used in skincare products. OBJECTIVE: This study develops and evaluates skin creams incorporated with bioactive S. platensis extract. MATERIALS AND METHODS: Spirulina platensis was cultivated, the aqueous crude extract was prepared and in vitro cytotoxicity of S...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28531863/biodiesel-production-from-spirulina-microalgae-feedstock-using-direct-transesterification-near-supercritical-methanol-condition
#11
Hamed Mohamadzadeh Shirazi, Javad Karimi-Sabet, Cyrus Ghotbi
Microalgae as a candidate for production of biodiesel, possesses a hard cell wall that prevents intracellular lipids leaving out from the cells. Direct or in situ supercritical transesterification has the potential for destruction of microalgae hard cell wall and conversion of extracted lipids to biodiesel that consequently reduces the total energy consumption. Response surface methodology combined with central composite design was applied to investigate process parameters including: Temperature, Time, Methanol-to-dry algae, Hexane-to-dry algae, and Moisture content...
September 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28499204/simultaneous-determination-of-nine-phytohormones-in-seaweed-and-algae-extracts-by-hplc-pda
#12
Bogusława Górka, Piotr P Wieczorek
An RP-HPLC-PDA method for the simultaneous analysis of 9 compounds deriving from the phytohormones class was developed and optimized, namely indoleacetic acid (IAA), indolebutyric acid (IBA), phenyleacetic acid (PAA), naphtyleacetic acid (NAA), trans-zeatin (TZ), kinetin (KA), isopentenyladenine (IA), 6-benzylaminopurine (6-BA) and abscisic acid (ABA). Validation of the method was performed on the SFE-CO2 extract made out of the mixture of Baltic algae. The regression coefficients for plant hormones were in the range from 0...
July 1, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28486198/mutation-of-spirulina-sp-by-nuclear-irradiation-to-improve-growth-rate-under-15-carbon-dioxide-in-flue-gas
#13
Jun Cheng, Hongxiang Lu, Xin He, Weijuan Yang, Junhu Zhou, Kefa Cen
Spirulina sp. was mutated by γ-rays from (60)Co nuclear irradiation to improve growth and CO2 fixation rate under 15vol.% CO2 (in flue gas from a power plant). Mutants with enhanced growth phenotype were obtained, with the best strain exhibiting 310% increment in biomass yield on day 4. The mutant was then domesticated with elevated CO2 concentration, and the biomass yield increased by 500% after domestication under 15vol.% CO2, with stable inheritance. Ultrastructure of Spirulina sp. shows that the fractal dimension of Spirulina cells decreased by 23% after mutation...
August 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28476990/higher-adsorption-capacity-of-spirulina-platensis-alga-for-cr-vi-ions-removal-parameter-optimisation-equilibrium-kinetic-and-thermodynamic-predictions
#14
Elumalai Gunasundari, Ponnusamy Senthil Kumar
This study discusses about the biosorption of Cr(VI) ion from aqueous solution using ultrasonic assisted Spirulina platensis (UASP). The prepared UASP biosorbent was characterised by Fourier transform infrared spectroscopy, X-ray diffraction, Brunauer-Emmet-Teller, scanning electron spectroscopy and energy dispersive X-ray and thermogravimetric analyses. The optimum condition for the maximum removal of Cr(VI) ions for an initial concentration of 50 mg/l by UASP was measured as: adsorbent dose of 1 g/l, pH of 3...
April 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28472600/glucomannan-or-glucomannan-plus-spirulina-enriched-squid-surimi-diets-reduce-histological-damage-to-liver-and-heart-in-zucker-fa-fa-rats-fed-a-cholesterol-enriched-and-non-cholesterol-enriched-atherogenic-diet
#15
Miguel Vázquez-Velasco, Laura González-Torres, Rosa A García-Fernández, María Teresa Méndez, Sara Bastida, Juana Benedí, María José González-Muñoz, Francisco J Sánchez-Muniz
Glucomannan-enriched squid surimi improves cholesterolemia and liver antioxidant status. The effect of squid surimi enriched with glucomannan or glucomannan plus spirulina on liver and heart structures and cell damage markers was tested in fa/fa rats fed highly saturated-hyper-energetic diets. Animals were fed 70% AIN-93M rodent diet plus six versions of 30% squid surimi for 7 weeks: control (C), glucomannan (G), and glucomannan plus spirulina (GS). The cholesterol-control (HC), cholesterol-glucomannan (HG), and cholesterol-glucomannan plus spirulina (HGS) groups were given similar diets that were enriched with 2% cholesterol and 0...
June 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28460930/jagua-blue-derived-from-genipa-americana-l-fruit-a-natural-alternative-to-commonly-used-blue-food-colorants
#16
J E Brauch, S P Zapata-Porras, M Buchweitz, J K Aschoff, R Carle
Due to consumers' increasing health awareness, food industry aims at replacing synthetic dyes by natural counterparts. The substitution of blue synthetic dyes is particularly challenging since current natural alternatives such as phycocyanin (Spirulina) suffer from poor stability. Jagua blue (produced from Genipa americana L. fruit) might represent a potential novel blue pigment source. However, only little is known about its color properties, and application in food systems. Therefore, the blue color and the stability of Jagua blue were assessed for the first time and compared to commonly used colorants, namely, Spirulina, brilliant blue FCF (Blue no...
November 2016: Food Research International
https://www.readbyqxmd.com/read/28441036/application-of-arthrospira-spirulina-platensis-biomass-for-silver-removal-from-aqueous-solutions
#17
Inga Zinicovscaia, Liliana Cepoi, Tatiana Chiriac, Tatiana Mitina, Dmitrii Grozdov, Nikita Yushin, Otilia Culicov
The cyanobacterium Arthrospira (Spirulina) platensis was used to study the process of silver biosorption. Effects of various parameters such as contact time, dosage of biosorbent, initial pH, temperature, and initial concentration of Ag(I) were investigated for a batch adsorption system. The optimal biosorption conditions were determined as pH 5.0, biosorbent dosage of 0.4 g, and initial silver concentration of 30 mg/L. Equilibrium adsorption data were analyzed by the Langmuir and Freundlich models - however, the Freundlich model provided a better fit with the experimental data...
April 25, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28431534/the-effects-of-spirulina-platensis-on-anthropometric-indices-appetite-lipid-profile-and-serum-vascular-endothelial-growth-factor-vegf-in-obese-individuals-a-randomized-double-blinded-placebo-controlled-trial
#18
Reihaneh Zeinalian, Mahdieh Abbasalizad Farhangi, Atefeh Shariat, Maryam Saghafi-Asl
BACKGROUND: In recent years, a great attention has been focused on Spirulina platensis as a source of potential valuable nutrients for prevention and treatment of chronic diseases. The objectives of the current study were to determine the effects of Spirulina platensis on anthropometric parameters, serum lipids, appetite and serum Vascular Endothelial Growth Factor (VEGF) in obese individuals. METHODS: In the current study sixty four obese individuals aged 20-50 years were enrolled and randomly allocated into two groups of intervention and placebo...
April 21, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28393188/a-heptameric-peptide-purified-from-spirulina%C3%A2-sp-gastrointestinal-hydrolysate-inhibits-angiotensin-i-converting-enzyme-and-angiotensin%C3%A2-ii-induced-vascular-dysfunction-in-human-endothelial-cells
#19
Seong-Yeong Heo, Seok-Chun Ko, Chang Su Kim, Gun-Woo Oh, Bomi Ryu, Zhong-Ji Qian, Geunhyung Kim, Won Sun Park, Il-Whan Choi, Thi Tuong Vy Phan, Soo-Jin Heo, Do-Hyung Kang, Myunggi Yi, Won-Kyo Jung
In this study, a marine microalga Spirulina sp.-derived protein was hydrolyzed using gastrointestinal enzymes to produce an angiotensin I (Ang I)-converting enzyme (ACE) inhibitory peptide. Following consecutive purification, the potent ACE inhibitory peptide was composed of 7 amino acids, Thr-Met‑Glu‑Pro‑Gly‑Lys-Pro (molecular weight, 759 Da). Analysis using the Lineweaver-Burk plot and molecular modeling suggested that the purified peptide acted as a mixed non-competitive inhibitor of ACE...
May 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28387444/comparative-modulation-of-levels-of-oxidative-stress-in-the-liver-of-anti-tuberculosis-drug-treated-wistar-rats-by-vitamin-b12-beta-carotene-and-spirulina-fusiformis-role-of-nf-kb-inos-il-6-and-il-10
#20
Sherry Joseph Martin, Evan Prince Sabina
PURPOSE: Isoniazid (INH) and Rifampicin (RIF) are known hepatotoxic agents. We compared the efficacy of Spirulina fusiformis and its active components vitamin B12 and beta-carotene in attenuating INH & RIF induced hepatotoxicity. We also tried to elucidate the inflammatory mechanism behind anti-tuberculosis drug induced hepatotoxicity. METHODS: INH & RIF were administered to Wistar albino rats for 28 days to induce hepatotoxicity. Spirulina fusiformis, vitamin B12 and beta-carotene were co-administered with INH & RIF and their hepatoprotective, antioxidant and immunomodulatory roles were studied through blood and liver analysis...
April 7, 2017: Journal of Cellular Biochemistry
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